Study on Horizontal Relative Diffusion in theTroposphere and Lower Stratosphere

The behaviour of relative diffusion theory and Gifford’s random-force theory for long-range atmospheric diffusion is examined. When a puff scale is smaller than the Lagrangian length scale, √2KTL, an accelerative relative diffusion region exists, i.e., σy∝ t 3/2. While the puff diffusion enters a two-dimensional turbulence region, in which the diffusion scale is larger than 500 km, or time scale is larger than 1 day, divergence and convergence are main cause of horizontal diffusion. Between the two above-mentioned regimes, diffusion deviation is given by σy = √2KT. The large-scale horizontal relative diffusion parameters were obtained by analyzing the data of radioactive cloud width collected in air nuclear tests. Key words Tropospheric and lower stratospheric diffusion - Relative diffusion - Large scale turbulence - Nuclear explosion clouds This work is sponsored by the National Natural Science Foundation of China under Grant No. 49505064.The author would like to thank Prof. Chen Jiayi Department of Geophysics of Peking University and Dr. Cai Xiaoming School of Geography and Environmental Sciences of Birmingham University for their helpful discussions.

Consistency between magnetic resonance diffusion-weighted images and pathological findings in a hyperacute cerebral infarction rabbit model

BACKGROUND： Because magnetic resonance diffusion-weighted imaging is sensitive to water molecule movement, it has particular advantages for early diagnosis of cerebral infarction. However, the relationship between apparent diffusion coefficient changes with ischemia time, particularly relative apparent diffusion coefficient and tissue pathological changes remains controversial. OBJECTIVE： To explore the correlation between apparent diffusion coefficient changes and pathologic changes in hyperacute cerebral infarction. DESIGN, TIME AND SETTING： A randomized, controlled, animal experiment of neuroimaging. The study was performed at the Laboratory of Radiology Department, Longgang Central Hospital of Shenzhen from October 2007 to October 2008. MATERIALS： Magnetic resonance scanner was purchased from Philips Medical Systems, Best, the Netherlands. METHODS： A total of 42 healthy, adult, New Zealand rabbits were randomly assigned into sham-operation, ischemia 0.5-, 1-, 2-, 3-, 4-, and 6-hour groups, with six animals in each group. Local cerebral ischemia model was established by right middle cerebral artery occlusion, and cranial MRI scanning and pathologic observation were performed, respectively, at 0.5, 1,2, 3, 4, and 6 hours following ischemia. The middle cerebral artery of sham-operation group was only exposed, but not occluded. Images at the above-mentioned time points were also collected. MAIN OUTCOME MEASURES： Apparent diffusion coefficient and relative apparent diffusion coefficient values of abnormal signal on diffusion-weighted imaging were calculated and compared with pathological changes in the ischemic region. RESULTS： No abnormal diffusion-weighted imaging signals or pathological changes were observed in the sham-operation group. Abnormal signal intensity on diffusion-weighted imaging was first observed in the 0.5-hour group. Apparent diffusion coefficient and relative apparent diffusion coefficient values decreased in all middle cerebral artery occlusion rabbits and reached lowest levels at 3 hours, followed by a gradual increase. The right ischemic basal ganglia region with high signal intensity on diffusion-weighted imaging extended with increasing time of occlusion, and the pathologic outcome corresponded with MRI changes. CONCLUSION： Relative apparent diffusion coefficient values changed regularly with ischemia time and displayed good correspondence to pathological manifestations.

A Fiber Tractography Study of Social-Emotional Related Fiber Tracts in Children and Adolescents with Autism Spectrum Disorder

The symptoms of autism spectrum disorder（ASD） have been hypothesized to be caused by changes in brain connectivity. From the clinical perspective, the‘‘disconnectivity＇＇ hypothesis has been used to explain characteristic impairments in ‘‘socio-emotional＇＇ function.Therefore, in this study we compared the facial emotional recognition（FER） feature and the integrity of socialemotional-related white-matter tracts between children and adolescents with high-functioning ASD（HFA） and their typically developing（TD） counterparts. The correlation between the two factors was explored to find out if impairment of the white-matter tracts is the neural basis of social-emotional disorders. Compared with the TD group,FER was significantly impaired and the fractional anisotropy value of the right cingulate fasciculus was increased in the HFA group（P ／ 0.01）. In conclusion, the FER function of children and adolescents with HFA was impaired and the microstructure of the cingulate fasciculus had abnormalities.

Relation between sound transfer function from diffuse sound field to the eardrum and temporary threshold shift

Twelve volunteers with normal hearing (9 males and 3 females) participated in this work The sound transfer functions (STFS) from diffuse sound field to the subject's eardrums were measured and correlated to the temporary threshold shift (TTS) due to fiffuse-exposure.A probe tube with a miniature microphone was used for STF measurements in which successive 1/3 oct bandwidth random noise with central frequency from 0.25 kKz to 8 kHz were used. The subjects were divided into two groups, with the STF maxima at 2 kHz and 4 kHz respectively Pre- and post- exposure sweep Bekesy audiograms were recorded and the temporary thresh old shift calctilated as the difference between the two. Frequency of the maximum TTS was correlated to that of the maximum STF. The average TTS was very small or zero at frequen cies below the band noise exposure , but was noticeable even at the highest measured frequency (8 kHz) for beyond the noise band. Also individual differences in STF were found at frequencies between 2 kHz and 4 kHz