Background:To explore the clinical effect of external application of ShouNian Powder combined with acupuncture at Zhitong acupoint in the treatment of intercostobrachial nerve syndrome(ICBNs)after breast cancer operat...Background:To explore the clinical effect of external application of ShouNian Powder combined with acupuncture at Zhitong acupoint in the treatment of intercostobrachial nerve syndrome(ICBNs)after breast cancer operation.Methods:A total of 80 patients with ICBNs who underwent modified radical mastectomy in our hospital from July 2014 to July 2016 were collected and divided into control group and study group according to the different treatment methods of ICBNs.40 patients in the control group were treated with symptomatic analgesia and 40 patients in the study group were treated with external application of ShouNian Powder combined with acupuncture at Zhitong acupoint to compare and analyze the pain relief,quality of life and analgesic recurrence rate of ICBNs between the two groups.Results:Compared with the control group,the pain relief rate of ICBNs in the study group was higher.The patient satisfaction and long-term quality of life in the study group were better than those in the control group.However,there was no significant difference in postoperative pain recurrence rate.Conclusion:External application of ShouNian Powder combined with acupuncture at Zhitong acupoint can effectively relieve pain and improve quality of life for patients with ICBNs after breast cancer operation,which has a certain popularizing significance in clinical practice.展开更多
Objective: To evaluate the clinical effect of Liqi Kuanxiong Huoxue method (宽胸活血,LKH, traditional Chinese medicine, TCM therapeutic method for regulating qi, relieving chest stuffiness and promoting blood circul...Objective: To evaluate the clinical effect of Liqi Kuanxiong Huoxue method (宽胸活血,LKH, traditional Chinese medicine, TCM therapeutic method for regulating qi, relieving chest stuffiness and promoting blood circulation) in treating patients with cardiac syndrome X (CSX). Methods: The prospective, non-randomized controlled study was conducted on 51 selected patients with CSX, who were non-randomly assigned to 2 groups, the treated group treated with LKH in addition to the conventional treatment (32 patients), and the control group treated with conventional treatment (19 patients) like nitrate, diltiazem hydrochloride, etc. The treatment course was 14 days. The changes of such symptoms as angina pectoris, TCM syndrome and indexes of treadmill exercise test before and after treatment were observed. Results: After treatment, such symptoms as chest pain and stuffy feeling and palpitation in the treated group were improved more than those in the control group (P〈0.05); the total effective rate on angina pectoris and TCM syndrome in the treated group was better than that in the control group (P〈0.05). The treadmill exercise test showed that the maximal metabolic equivalent (Max MET), the time of angina onset and ST segment depression by 0.1 mV were obviously improved after treatment in both groups, but the improvement in the treated group was better than that in the control group respectively (P〈0.05). Conclusion: The LKH method could reduce the frequency of angina attacks and improve the clinical condition of patients with CSX.展开更多
程序性死亡受体1(programmed cell death protein 1,PD-1)抑制剂能够恢复免疫T细胞的活性,从而识别并清除肿瘤细胞,目前已被广泛应用于晚期肺癌患者的治疗。然而PD-1抑制剂也会耐药,导致肿瘤恶化进展。中医治疗肺癌方面,益气扶正化痰法...程序性死亡受体1(programmed cell death protein 1,PD-1)抑制剂能够恢复免疫T细胞的活性,从而识别并清除肿瘤细胞,目前已被广泛应用于晚期肺癌患者的治疗。然而PD-1抑制剂也会耐药,导致肿瘤恶化进展。中医治疗肺癌方面,益气扶正化痰法是主要治法之一,临床应用广泛。本文介绍中医药联合PD-1免疫抑制剂治疗晚期肺癌1例,并探讨少阳证与PD-1免疫抑制的关系。前期中医以益气扶正,化痰抑瘤为治法,中西结合治疗获得近1年的肿瘤稳定后恶化进展,考虑PD-1免疫药物耐药。后改从少阳论治,以化痰解郁抑瘤为法,予经方半夏厚朴汤合葶苈大枣泻肺汤加减辨治2月后,复查肿瘤明显缩小、胸腔积液基本消失,获得良效。展开更多
文摘Background:To explore the clinical effect of external application of ShouNian Powder combined with acupuncture at Zhitong acupoint in the treatment of intercostobrachial nerve syndrome(ICBNs)after breast cancer operation.Methods:A total of 80 patients with ICBNs who underwent modified radical mastectomy in our hospital from July 2014 to July 2016 were collected and divided into control group and study group according to the different treatment methods of ICBNs.40 patients in the control group were treated with symptomatic analgesia and 40 patients in the study group were treated with external application of ShouNian Powder combined with acupuncture at Zhitong acupoint to compare and analyze the pain relief,quality of life and analgesic recurrence rate of ICBNs between the two groups.Results:Compared with the control group,the pain relief rate of ICBNs in the study group was higher.The patient satisfaction and long-term quality of life in the study group were better than those in the control group.However,there was no significant difference in postoperative pain recurrence rate.Conclusion:External application of ShouNian Powder combined with acupuncture at Zhitong acupoint can effectively relieve pain and improve quality of life for patients with ICBNs after breast cancer operation,which has a certain popularizing significance in clinical practice.
基金Priority Project of Tianjin Science Technical Commission (No. 05YFGDSF02200)Yan De-xin Foundation Project (No. 05-012)
文摘Objective: To evaluate the clinical effect of Liqi Kuanxiong Huoxue method (宽胸活血,LKH, traditional Chinese medicine, TCM therapeutic method for regulating qi, relieving chest stuffiness and promoting blood circulation) in treating patients with cardiac syndrome X (CSX). Methods: The prospective, non-randomized controlled study was conducted on 51 selected patients with CSX, who were non-randomly assigned to 2 groups, the treated group treated with LKH in addition to the conventional treatment (32 patients), and the control group treated with conventional treatment (19 patients) like nitrate, diltiazem hydrochloride, etc. The treatment course was 14 days. The changes of such symptoms as angina pectoris, TCM syndrome and indexes of treadmill exercise test before and after treatment were observed. Results: After treatment, such symptoms as chest pain and stuffy feeling and palpitation in the treated group were improved more than those in the control group (P〈0.05); the total effective rate on angina pectoris and TCM syndrome in the treated group was better than that in the control group (P〈0.05). The treadmill exercise test showed that the maximal metabolic equivalent (Max MET), the time of angina onset and ST segment depression by 0.1 mV were obviously improved after treatment in both groups, but the improvement in the treated group was better than that in the control group respectively (P〈0.05). Conclusion: The LKH method could reduce the frequency of angina attacks and improve the clinical condition of patients with CSX.
文摘程序性死亡受体1(programmed cell death protein 1,PD-1)抑制剂能够恢复免疫T细胞的活性,从而识别并清除肿瘤细胞,目前已被广泛应用于晚期肺癌患者的治疗。然而PD-1抑制剂也会耐药,导致肿瘤恶化进展。中医治疗肺癌方面,益气扶正化痰法是主要治法之一,临床应用广泛。本文介绍中医药联合PD-1免疫抑制剂治疗晚期肺癌1例,并探讨少阳证与PD-1免疫抑制的关系。前期中医以益气扶正,化痰抑瘤为治法,中西结合治疗获得近1年的肿瘤稳定后恶化进展,考虑PD-1免疫药物耐药。后改从少阳论治,以化痰解郁抑瘤为法,予经方半夏厚朴汤合葶苈大枣泻肺汤加减辨治2月后,复查肿瘤明显缩小、胸腔积液基本消失,获得良效。