Objective:To investigate the correlation of abdominal aorta CT value,renal artery CT value and renal cortex thickness with renal cortex CT value on contrast enhanced 64-slice CT images.Methods:96patients(50 men and 46...Objective:To investigate the correlation of abdominal aorta CT value,renal artery CT value and renal cortex thickness with renal cortex CT value on contrast enhanced 64-slice CT images.Methods:96patients(50 men and 46women;16~74years)with normal kidney function,which was confirmed by kidney function test were enrolled in this study,including bilateral kidneys of 92cases and unilateral kidney of 4cases(total of 188kidneys;92left,96right).After intravenous(IV)injection of contrast agent the kidneys of the selected patients were scanned by MDCT.The scans were performed in arterial,venous and 3min delayed phases.All statistical analyses were performed by using IBM SPSS 20.0.Graphs were generated using Graph Pad Prism 5software.Quantitative data were presented as mean±standard deviation,while qualitative data were presented as frequency(%).P<0.05was considered to be statistically significant.Results:The mean renal cortex thickness was(5.19±0.81)mm in all kidneys.In the arterial phase,a statistically significant positive correlation between renal cortex CT values and abdominal aortic CT values was showed(r=0.584;P<0.001).A statistically significant positive correlation between renal cortex CT values and renal cortex thickness was demonstrated(r=0.533,P<0.0001).Likewise,there was a positive correlation between renal cortex CT value and renal artery CT values(r=0.43,P<0.001).Conclusion:It is a promising approach to assess the individual kidney function by measuring abdominal aorta CT value,renal artery CT value,renal cortex CT value and renal cortex thickness using contrast MDCT.展开更多
目的:评价实时谐波超声造影技术定量分析正常人肾脏灌注的可行性。材料和方法:采用PHILIPS I-U-22超声仪器对45例正常人进行双肾实时超声造影,超声对比剂为SonoVue,每侧肾脏使用剂量为1ml。每次原始数据经过Qlab灌注定量分析软件处理。...目的:评价实时谐波超声造影技术定量分析正常人肾脏灌注的可行性。材料和方法:采用PHILIPS I-U-22超声仪器对45例正常人进行双肾实时超声造影,超声对比剂为SonoVue,每侧肾脏使用剂量为1ml。每次原始数据经过Qlab灌注定量分析软件处理。比较双肾皮质超声灌注的差异,并用TIC曲线对肾脏皮质设置不同感兴趣区域(region of interest,ROI)进行定量灌注参数对比分析。结果:实时超声造影能清晰显示肾脏皮质灌注的过程。左肾与右肾皮质同一灌注参数无显著性差异,不同ROI测得的达峰时间、曲线下降支斜率之间无显著性差异,而曲线下面积、达峰强度绝对值、曲线上升支斜率之间有显著性差异。结论:实时谐波超声造影技术能定量分析肾脏皮质血流灌注的特点,不同的ROI在同一灌注参数的测量上具有一致性。展开更多
目的探讨梗阻性黄疸大鼠肾皮质血液灌流量的变化及丹参的治疗作用。方法将SD大鼠分为假手术组(A组),胆总管结扎组(B组),丹参干预组(C组),每组分3,7,10 d 3个时相,每个时相8只。应用LISCA激光多普勒组织灌流图像仪以及血液灌流图像分析...目的探讨梗阻性黄疸大鼠肾皮质血液灌流量的变化及丹参的治疗作用。方法将SD大鼠分为假手术组(A组),胆总管结扎组(B组),丹参干预组(C组),每组分3,7,10 d 3个时相,每个时相8只。应用LISCA激光多普勒组织灌流图像仪以及血液灌流图像分析系统观测各组相应时相肾皮质血液灌流量的变化。检测血尿素氮(BUN),肌酐(Cr)水平。结果B组与A组比较各时相肾皮质血液灌流值减小,并随时间延长减小更加明显(P<0.05)。7,10 d组血BUN,Cr水平升高(P<0.05)。C组与B组比较各时相肾皮质血液灌流值增大(P<0.05),10 d组血BUN,Cr水平下降(P<0.05)。结论梗阻性黄疸可以导致大鼠肾皮质血液灌流量减少;丹参注射液能够增加肾皮质血液灌流量。展开更多
文摘Objective:To investigate the correlation of abdominal aorta CT value,renal artery CT value and renal cortex thickness with renal cortex CT value on contrast enhanced 64-slice CT images.Methods:96patients(50 men and 46women;16~74years)with normal kidney function,which was confirmed by kidney function test were enrolled in this study,including bilateral kidneys of 92cases and unilateral kidney of 4cases(total of 188kidneys;92left,96right).After intravenous(IV)injection of contrast agent the kidneys of the selected patients were scanned by MDCT.The scans were performed in arterial,venous and 3min delayed phases.All statistical analyses were performed by using IBM SPSS 20.0.Graphs were generated using Graph Pad Prism 5software.Quantitative data were presented as mean±standard deviation,while qualitative data were presented as frequency(%).P<0.05was considered to be statistically significant.Results:The mean renal cortex thickness was(5.19±0.81)mm in all kidneys.In the arterial phase,a statistically significant positive correlation between renal cortex CT values and abdominal aortic CT values was showed(r=0.584;P<0.001).A statistically significant positive correlation between renal cortex CT values and renal cortex thickness was demonstrated(r=0.533,P<0.0001).Likewise,there was a positive correlation between renal cortex CT value and renal artery CT values(r=0.43,P<0.001).Conclusion:It is a promising approach to assess the individual kidney function by measuring abdominal aorta CT value,renal artery CT value,renal cortex CT value and renal cortex thickness using contrast MDCT.
文摘目的:评价实时谐波超声造影技术定量分析正常人肾脏灌注的可行性。材料和方法:采用PHILIPS I-U-22超声仪器对45例正常人进行双肾实时超声造影,超声对比剂为SonoVue,每侧肾脏使用剂量为1ml。每次原始数据经过Qlab灌注定量分析软件处理。比较双肾皮质超声灌注的差异,并用TIC曲线对肾脏皮质设置不同感兴趣区域(region of interest,ROI)进行定量灌注参数对比分析。结果:实时超声造影能清晰显示肾脏皮质灌注的过程。左肾与右肾皮质同一灌注参数无显著性差异,不同ROI测得的达峰时间、曲线下降支斜率之间无显著性差异,而曲线下面积、达峰强度绝对值、曲线上升支斜率之间有显著性差异。结论:实时谐波超声造影技术能定量分析肾脏皮质血流灌注的特点,不同的ROI在同一灌注参数的测量上具有一致性。
文摘目的探讨梗阻性黄疸大鼠肾皮质血液灌流量的变化及丹参的治疗作用。方法将SD大鼠分为假手术组(A组),胆总管结扎组(B组),丹参干预组(C组),每组分3,7,10 d 3个时相,每个时相8只。应用LISCA激光多普勒组织灌流图像仪以及血液灌流图像分析系统观测各组相应时相肾皮质血液灌流量的变化。检测血尿素氮(BUN),肌酐(Cr)水平。结果B组与A组比较各时相肾皮质血液灌流值减小,并随时间延长减小更加明显(P<0.05)。7,10 d组血BUN,Cr水平升高(P<0.05)。C组与B组比较各时相肾皮质血液灌流值增大(P<0.05),10 d组血BUN,Cr水平下降(P<0.05)。结论梗阻性黄疸可以导致大鼠肾皮质血液灌流量减少;丹参注射液能够增加肾皮质血液灌流量。