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DOX-CONJUGATED HIGH-QUALITY AgZnInS QDs FOR REVERSAL OF MULTIDRUG RESISTANCE
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作者 LINGZHI QU DAWEI DENG +1 位作者 JIE WANG YUEQING GU 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2014年第1期33-39,共7页
The synthesis of water-soluble quantum dots(QDs)has recently received extensive attention dueto noninvasive detection of biological information in living subjects.In this paper,high-qualitywater-soluble(cadmium-free)q... The synthesis of water-soluble quantum dots(QDs)has recently received extensive attention dueto noninvasive detection of biological information in living subjects.In this paper,high-qualitywater-soluble(cadmium-free)quaternary AgZnlnS QDs have been successfully synthesized usinga green synthetic route.The as-prepared QDs exhibit tunable photoluminescence(PL)emissionbetween 521 and 658 nm.Secondly,multidrug resistance(MDR)is a major impedinent to theeffective cancer chemot herapy,DOx,a widely used antit umor drug was modified on the surfaceof the QDs in this study.It,therefore,ignificantly enhanced the cytotoxicity of DX to MDRcancer cells as the QDs could bring the DoX to nucleus. 展开更多
关键词 AgZnlnS QDs DOXORUBICIN multidrug resist ance(MDR).
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