In a recent issue ot World Journal of Gastroenterology, Demeter et al., reported that in patients having both gastro-esophageal reflux disease （GERD） and obstructive sleep apnea （OSA）, there was a positive correla...In a recent issue ot World Journal of Gastroenterology, Demeter et al., reported that in patients having both gastro-esophageal reflux disease （GERD） and obstructive sleep apnea （OSA）, there was a positive correlation between endoscopic findings of GERD and the number of apneas and hypopneas per hour, namely apnea hypopnea index. They proposed that the severity of OSA and GERD are parallel to each other. The study of Demeter and colleagues is very important, not only for assessing reflux-induced esophageal damage in OSA,展开更多
Objective To study the clinical characteristics of obstructive sleep apnea syndrome (OSAS) induced acute respiratory failure. Methods The clinical and laboratory character,isties of 9 patients were reviewed. Results 9...Objective To study the clinical characteristics of obstructive sleep apnea syndrome (OSAS) induced acute respiratory failure. Methods The clinical and laboratory character,isties of 9 patients were reviewed. Results 9 patients (8 females, 1 male) presented with obesity and mental disturbance, with a BMI heing 44. 97 kg/m2, (45. 25 kg/m2 in the female). The mean age of the group wes 67. 89 years (61 ~ 74 years). All had respiratory acidosis (mean pH 7. 17), hypercapnia (mean PaCO2 94. 10mmHg) (63. 97 ~ 143. 18mmHg), and hypoxemia (mean PaO2 39mmHg ) (29. 03 ~ 44. 03mmHg). During periods of clinical stability all but 2 had awaken hypercapnia (mean PaCO2 46. 73mmHg) (38. 25 ~ 54. 68mmHg). Four of the 9 patients had pulmonary function test showing FEV1 > 70%. Conclusion OSAS induced acute respiratory fail- ure has a sudden onset and curious presentations and can be reversed with early and proper treatment. The seventy of abnormal pulmonary function wes less than what could be expeted to cause respiratory.atory failure.展开更多
文摘In a recent issue ot World Journal of Gastroenterology, Demeter et al., reported that in patients having both gastro-esophageal reflux disease （GERD） and obstructive sleep apnea （OSA）, there was a positive correlation between endoscopic findings of GERD and the number of apneas and hypopneas per hour, namely apnea hypopnea index. They proposed that the severity of OSA and GERD are parallel to each other. The study of Demeter and colleagues is very important, not only for assessing reflux-induced esophageal damage in OSA,
文摘Objective To study the clinical characteristics of obstructive sleep apnea syndrome (OSAS) induced acute respiratory failure. Methods The clinical and laboratory character,isties of 9 patients were reviewed. Results 9 patients (8 females, 1 male) presented with obesity and mental disturbance, with a BMI heing 44. 97 kg/m2, (45. 25 kg/m2 in the female). The mean age of the group wes 67. 89 years (61 ~ 74 years). All had respiratory acidosis (mean pH 7. 17), hypercapnia (mean PaCO2 94. 10mmHg) (63. 97 ~ 143. 18mmHg), and hypoxemia (mean PaO2 39mmHg ) (29. 03 ~ 44. 03mmHg). During periods of clinical stability all but 2 had awaken hypercapnia (mean PaCO2 46. 73mmHg) (38. 25 ~ 54. 68mmHg). Four of the 9 patients had pulmonary function test showing FEV1 > 70%. Conclusion OSAS induced acute respiratory fail- ure has a sudden onset and curious presentations and can be reversed with early and proper treatment. The seventy of abnormal pulmonary function wes less than what could be expeted to cause respiratory.atory failure.
