Rh(III)‐catalyzed C–H activation of N‐protected anilines and chemo‐divergent couplings with acroleins/enones have been realized for synthesis of three classes of heterocycles.The oxidative coupling of N‐pyridylan...Rh(III)‐catalyzed C–H activation of N‐protected anilines and chemo‐divergent couplings with acroleins/enones have been realized for synthesis of three classes of heterocycles.The oxidative coupling of N‐pyridylaniline afforded dihydroquinolones with the acrolein being a major hydrogen acceptor.When the directing group was replaced by pyrimidyl in the same system,redox‐neutral coupling occurred to afford hemiaminal ethers.Oxidative annulation of N‐pyridylanilines with enones using AgBF4 oxidant afforded atropisomeric quinolinium salts.展开更多
基金supported by the National Nature Science Foundation of China(21525208,21472186)the fund for new technology of methanol conversion of Dalian Institute of Chemical Physics(Chinese Academy of Sciences)~~
文摘Rh(III)‐catalyzed C–H activation of N‐protected anilines and chemo‐divergent couplings with acroleins/enones have been realized for synthesis of three classes of heterocycles.The oxidative coupling of N‐pyridylaniline afforded dihydroquinolones with the acrolein being a major hydrogen acceptor.When the directing group was replaced by pyrimidyl in the same system,redox‐neutral coupling occurred to afford hemiaminal ethers.Oxidative annulation of N‐pyridylanilines with enones using AgBF4 oxidant afforded atropisomeric quinolinium salts.
