Objective:To investigate detection and significance of IgG anti-G in serum and erythrocyte irradiation fluid of patients with Rh hemolytic disease of newborn.Methods:It was sensitized with O ccDee (Ccdee) standard ery...Objective:To investigate detection and significance of IgG anti-G in serum and erythrocyte irradiation fluid of patients with Rh hemolytic disease of newborn.Methods:It was sensitized with O ccDee (Ccdee) standard erythrocyte that the serum and the irradiation fluid contained anti-D or/and anti-C identified with spectra cello. The sensitized erythrocyte was irradiated by indirect coomb test was used to identify IgG anti-G of the irradiation fluid with O Ccdee (ccDee).Results:There were anti-G in 3 patients’ serum or/and irradiation fluid and gravidas’ serum of 11 patients with Rh hemolytic disease and gravidas’o. And gravidas’ Rh blood group were all ccdee.Conclusion:Anti-G can occur in newborn when gravida’s Rh blood group is ccdee. It must be paid attention to that anti-G could intensify patients haemolysis in clinic blood transfusion.展开更多
新生儿溶血病（hemolytic disease of the newborn）是指母、婴血型不合引起的新生儿同种免疫性溶血性疾病。临床上以ABO血型不合引起的新生儿溶血病最常见,其次为RH血型系统,后者又以RHD血型不合引起的新生儿溶血病常见,而非抗D抗体引...新生儿溶血病（hemolytic disease of the newborn）是指母、婴血型不合引起的新生儿同种免疫性溶血性疾病。临床上以ABO血型不合引起的新生儿溶血病最常见,其次为RH血型系统,后者又以RHD血型不合引起的新生儿溶血病常见,而非抗D抗体引起的新生儿溶血病报道较少[1-3]。本文报道我院收治的2例非抗D抗体引起的新生儿RH溶血病,提高临床医师对本病在预防及治疗方面的认识。展开更多
目的分析严重Rh溶血病并发持续肺动脉高压(persistent pulmonary hypertension of newborn,PPHN)、肺出血的原因,以便早期诊断及治疗,降低病死率。方法回顾性分析严重Rh溶血病患儿并发PPHN、肺出血的临床病历资料,并对病因、发病机制进...目的分析严重Rh溶血病并发持续肺动脉高压(persistent pulmonary hypertension of newborn,PPHN)、肺出血的原因,以便早期诊断及治疗,降低病死率。方法回顾性分析严重Rh溶血病患儿并发PPHN、肺出血的临床病历资料,并对病因、发病机制进行文献复习。结果严重Rh溶血病、极重度贫血可以合并PPHN、肺出血,经一氧化氮吸入、高频通气及支持对症治疗好转。结论新生儿严重溶血病出现低氧性呼吸衰竭要注意PPHN,治疗过程中呼吸支持联合NO治疗是成功的保证,同时注意液体管理、心肺功能监测及血凝监测。早期诊断、综合治疗是提高生存率的关键。展开更多
文摘Objective:To investigate detection and significance of IgG anti-G in serum and erythrocyte irradiation fluid of patients with Rh hemolytic disease of newborn.Methods:It was sensitized with O ccDee (Ccdee) standard erythrocyte that the serum and the irradiation fluid contained anti-D or/and anti-C identified with spectra cello. The sensitized erythrocyte was irradiated by indirect coomb test was used to identify IgG anti-G of the irradiation fluid with O Ccdee (ccDee).Results:There were anti-G in 3 patients’ serum or/and irradiation fluid and gravidas’ serum of 11 patients with Rh hemolytic disease and gravidas’o. And gravidas’ Rh blood group were all ccdee.Conclusion:Anti-G can occur in newborn when gravida’s Rh blood group is ccdee. It must be paid attention to that anti-G could intensify patients haemolysis in clinic blood transfusion.
文摘新生儿溶血病（hemolytic disease of the newborn）是指母、婴血型不合引起的新生儿同种免疫性溶血性疾病。临床上以ABO血型不合引起的新生儿溶血病最常见,其次为RH血型系统,后者又以RHD血型不合引起的新生儿溶血病常见,而非抗D抗体引起的新生儿溶血病报道较少[1-3]。本文报道我院收治的2例非抗D抗体引起的新生儿RH溶血病,提高临床医师对本病在预防及治疗方面的认识。
文摘目的分析严重Rh溶血病并发持续肺动脉高压(persistent pulmonary hypertension of newborn,PPHN)、肺出血的原因,以便早期诊断及治疗,降低病死率。方法回顾性分析严重Rh溶血病患儿并发PPHN、肺出血的临床病历资料,并对病因、发病机制进行文献复习。结果严重Rh溶血病、极重度贫血可以合并PPHN、肺出血,经一氧化氮吸入、高频通气及支持对症治疗好转。结论新生儿严重溶血病出现低氧性呼吸衰竭要注意PPHN,治疗过程中呼吸支持联合NO治疗是成功的保证,同时注意液体管理、心肺功能监测及血凝监测。早期诊断、综合治疗是提高生存率的关键。
