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顽固性高血压新疗法:激活动脉压力感受性反射 被引量:2
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作者 张丽丽 程磊 +1 位作者 苏定冯 刘爱军 《中国药理学通报》 CAS CSCD 北大核心 2013年第7期889-892,共4页
顽固性高血压约占高血压患病总人群的20%~30%,是影响公众健康的一大难题。压力感受性反射激活疗法(BAT)通过电刺激颈动脉窦压力感受器激活压力感受性反射,可明显降低血压、心率等。据此,美国CVRx研发出"Rheos",植入到颈动脉... 顽固性高血压约占高血压患病总人群的20%~30%,是影响公众健康的一大难题。压力感受性反射激活疗法(BAT)通过电刺激颈动脉窦压力感受器激活压力感受性反射,可明显降低血压、心率等。据此,美国CVRx研发出"Rheos",植入到颈动脉窦附近,可以慢性激活压力感受性反射,用于治疗顽固性高血压和重症心衰。其治疗机制可总结为:通过抑制交感神经和兴奋迷走神经,减少肾素的分泌,缓慢地增加肾脏的排泄功能,同时降低心率,扩张血管减少外周阻力,进而降低了动脉压同时促进钠平衡。 展开更多
关键词 顽固性高血压 压力感受性反射 压力感受性反射激 活疗法 rheos 机制
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Grain Size Control of Semisolid A356 Alloy Manufactured by Electromagnetic Stirring 被引量:23
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作者 P.K.Seo C.G.Kang 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2005年第2期219-225,共7页
To investigate the possibility of substituting the mechanical stirring system with electromagnetic stirring (EMS) system for aluminum rheo die-casting, the EMS under the different stirring cooling conditions was carri... To investigate the possibility of substituting the mechanical stirring system with electromagnetic stirring (EMS) system for aluminum rheo die-casting, the EMS under the different stirring cooling conditions was carried out. It was found that in the early period of solidification, the dendrite breakages led to a fine primary phase. When dendrites grew coarsely, the effect of ripening on grain size overwhelmed that of dendrite breakage. It was also found that the high cooling rate favored large nucleation rate, and led to a fine primary phase. But high cooling rate also made the growth rate of the dendrite arm, which prevented the dendrite arm from being sheared off. Therefore there were a suitable stirring time and suitable cooling rate to obtain the best rheo die-casting structure. Qualified semisolid A356 aluminum alloy was successfully manufactured with short time EMS. 展开更多
关键词 Semisolid metal process Electromagnetic stirring Rheo die-casting Grain size control
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