Two new dimeric diterpenes, birhodomolleins D （1） and E （2）, were characterized from the fruits of Rhododendron pumilum. Their structures featured two grayanane diterpenes dimerized through an oxygen bridge locati...Two new dimeric diterpenes, birhodomolleins D （1） and E （2）, were characterized from the fruits of Rhododendron pumilum. Their structures featured two grayanane diterpenes dimerized through an oxygen bridge locating at C-3 and C-2＇. They are the first examples of dimeric grayanane diterpenes with a 3-O-2＇ linkage from the Ericaceae family. Their structures were elucidated on the basis of comprehensive analysis of spectroscopic data.展开更多
基金the financial support of the National Science & Technology Major Project“Key New Drug Creation and Manufacturing Program”(No.2015ZX09103002)the National Natural Science Fundation of China(No.81673327)the grants from the Key Laboratory of Drug Research, Shanghai Institute of Materia Medica(No. SIMM1501ZZ-03)
文摘Two new dimeric diterpenes, birhodomolleins D （1） and E （2）, were characterized from the fruits of Rhododendron pumilum. Their structures featured two grayanane diterpenes dimerized through an oxygen bridge locating at C-3 and C-2＇. They are the first examples of dimeric grayanane diterpenes with a 3-O-2＇ linkage from the Ericaceae family. Their structures were elucidated on the basis of comprehensive analysis of spectroscopic data.
