Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Assoc...Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Association functional class. There is no consensus on the optimal surgical technique for this condition, including on whether to perform the procedure on a beating or an arrested heart and whether to perform valve repair or replacement. Methods: We analyzed four case series between 2015 and 2022 in which patients with secondary tricuspid regurgitation (TR) underwent valve repair on a beating heart and right atrial plication for a dilated right atrium. The TRI-SCORE was calculated for each patient. Results: All patients experienced a favorable postoperative course with significant improvements in heart failure symptoms. TR was markedly reduced;however, in one patient with concomitant mitral regurgitation (MR) and a high TRI-SCORE, MR worsened postoperatively. This patient later died from unknown causes due to multiple comorbidities in the late phase. Conclusions: Tricuspid valve repair on a beating heart was effective for improving the cardiac function, and the TRI-SCORE proved useful as a preoperative risk assessment tool. The underlying mechanism by which TR exacerbates MR requires further investigation.展开更多
Objective Assessment of right ventricular function in patients with atrial septal defect (ASD) is difficult. The Doppler myocardial performance index (MPI) may provide a method of assessing function in these patients....Objective Assessment of right ventricular function in patients with atrial septal defect (ASD) is difficult. The Doppler myocardial performance index (MPI) may provide a method of assessing function in these patients. The purposes of this study were to evaluate the right ventricular function and its changes in patients with ASD after transcatheter closure of ASD. Methods MPI, defined as the sum of isovolumic relaxation time and isovolumic contraction time derived by ejection time, was measured from tricuspid inflow and right ventricular outflow;Doppler velocity profiles recorded during routine echocardiography.Twenty nine patients (13 men, 16 women;mean age 25.28±12.69, range 6 to 57 years) were diagnosed to secundum ASD [the stretched diameters of ASD were from 9 To 36 (24.91±7.98) mm], and had a successfully placed Amplatzer septal occluder (ASO) (the sizes of ASO were from 11 to 40 mm );there were 81 sex-matched, age-matched healthy people (control group 41men, 40 women;mean age 29.02 ± 14.22, range 4 to 45 years ). MPI was measured again on 3 days and 1 month after closure of ASD. Change in the study group was assessed and compared to the control subjects with structurally normal hearts. A complete 2-dimensional and Doppler echocardiographic examination was performed in all study groups. Results 1) The isovolumic relaxation and isovolumic contraction times [respectively(77.59 ± 14.39)ms vs (60.93 ±12.94)ms, P<0.0001;(28.28 ±10.88)ms vs (23.64 ±9.01)ms, P=0.027] were prolonged, and ejection time [(260.65 ±21.86 )ms vs (271.85 ± 21.92)ms, P=0.033] was shortened in patients with ASD compared with that in control subjects, resulting in a marked increase in the MPI(0.40 ± 0.07 vs 0.31 ± 0.05, P<0.0001) from normal values;2) by Pearson's correlations, the MPI had no correlation with heart rate and blood pressure in control subjects and patients with ASD, but it correlated positively with age in patients with ASD;3) by Pearson's correlations, the MPI correlated positively with the diameter of ASD and pulmonary artery pressure;4) after transcatheter closure of ASD, the MPI decreased markedly. Conclusions 1) MPI is a conceptually new, simple, and reproducible Doppler index in patients with ASD;2) MPI is free from the effect of age, heart rate and blood pressure;(3) MPI appears to be relatively dependent on changes in the diameter of ASD and pulmonary artery pressure;4) the right ventricular function was improved after transcatheter closure of ASD.(J Geriatr Cardiol 2007;4:220-224.)展开更多
目的探讨多模态超声心动图对肺动脉高压患者右心功能的诊断效能。方法选取2022年1月至2023年8月于金华市中心医院就诊的80例肺动脉高压患者纳入观察组,根据患者的肺动脉收缩压将其分为轻度组[40~50mmHg(1mmHg=0.133kPa),36例]、中度组(5...目的探讨多模态超声心动图对肺动脉高压患者右心功能的诊断效能。方法选取2022年1月至2023年8月于金华市中心医院就诊的80例肺动脉高压患者纳入观察组,根据患者的肺动脉收缩压将其分为轻度组[40~50mmHg(1mmHg=0.133kPa),36例]、中度组(51~70mmHg,20例)和重度组(>70mmHg,24例);选取同期健康体检者80名纳入对照组,所有受试者均进行多模态超声心动图检测,对比其超声检查相关数据,评估多模态超声心动图对肺动脉高压患者右室收缩功能的诊断效能。结果观察组患者的右室舒张末期容积(right ventricular end diastolic volume,RVEDV)、右室收缩末期容积(right ventricular end systolic volume,RVESV)、右室整体无效做功(right ventricular global waste work,RVGWW)均显著高于对照组,右室每搏输出量(right ventricular stroke volume,RVSV)、右室射血分数(right ventrical ejection fraction,RVEF)、三尖瓣环收缩期位移(tricuspid annular plane systolic excusion,TAPSE)、整体纵向应变(global longitudinal strain,GLS)、右室整体做功效率(right ventricular global work efficiency,RVGWE)、右室整体做功指数(right ventricular global work index,RVGWI)、右室整体有效做功(right ventricular global constructive work,RVGCW)均显著低于对照组(P<0.05)。重度组患者的RVEDV、RVESV及RVGWW均显著高于中度组、轻度组,RVSV、RVEF、RVGWE、RVGWI、RVGCW均显著低于中度组、轻度组(P<0.05)。TAPSE、GLS、RVSV、RVEF、RVGWI五项联合诊断肺动脉高压患者右心功能的曲线下面积为0.911,敏感度为92.23%,特异性为96.45%。结论多模态超声心动图能有效评价肺动脉高压患者的右室收缩功能,值得临床推广应用。展开更多
Background： To determine the influence of right ventricular function in patients with constrictive pericarditis （CP） undergoing surgery and to compare the outcomes of patients who received surgery with those manage...Background： To determine the influence of right ventricular function in patients with constrictive pericarditis （CP） undergoing surgery and to compare the outcomes of patients who received surgery with those managed medically. Methods： Patients with the diagnosis of CP and healthy volunteers were recruited from January 2006 to November 2011. Patients with CP chose to either receive pericardiectomy or medical management. Echocardiographic measurements were performed to evaluate heart function, and survival was recorded. Results： A total of 58 patients with CP （36 received pericardiectomy, 22 managed medically）, and 43 healthy volunteers were included. CP patients who received surgery had a higher survival rate than those managed medically （P = 0.003）, and higher st, rvival was also seen in the subgroup of CP patients with severely impaired right systolic function. Albumin level, left ventricular end-diastolic dimension, and tricuspid regurgitation velocity were associated with survival in CP patients who received surgery. Conclusions： Preoperative right heart function does not affect surgical outcomes. Patients with severely impaired preoperative right systolic function obtain a greater survival advantage with surgery than with medical treatment.展开更多
文摘Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Association functional class. There is no consensus on the optimal surgical technique for this condition, including on whether to perform the procedure on a beating or an arrested heart and whether to perform valve repair or replacement. Methods: We analyzed four case series between 2015 and 2022 in which patients with secondary tricuspid regurgitation (TR) underwent valve repair on a beating heart and right atrial plication for a dilated right atrium. The TRI-SCORE was calculated for each patient. Results: All patients experienced a favorable postoperative course with significant improvements in heart failure symptoms. TR was markedly reduced;however, in one patient with concomitant mitral regurgitation (MR) and a high TRI-SCORE, MR worsened postoperatively. This patient later died from unknown causes due to multiple comorbidities in the late phase. Conclusions: Tricuspid valve repair on a beating heart was effective for improving the cardiac function, and the TRI-SCORE proved useful as a preoperative risk assessment tool. The underlying mechanism by which TR exacerbates MR requires further investigation.
文摘Objective Assessment of right ventricular function in patients with atrial septal defect (ASD) is difficult. The Doppler myocardial performance index (MPI) may provide a method of assessing function in these patients. The purposes of this study were to evaluate the right ventricular function and its changes in patients with ASD after transcatheter closure of ASD. Methods MPI, defined as the sum of isovolumic relaxation time and isovolumic contraction time derived by ejection time, was measured from tricuspid inflow and right ventricular outflow;Doppler velocity profiles recorded during routine echocardiography.Twenty nine patients (13 men, 16 women;mean age 25.28±12.69, range 6 to 57 years) were diagnosed to secundum ASD [the stretched diameters of ASD were from 9 To 36 (24.91±7.98) mm], and had a successfully placed Amplatzer septal occluder (ASO) (the sizes of ASO were from 11 to 40 mm );there were 81 sex-matched, age-matched healthy people (control group 41men, 40 women;mean age 29.02 ± 14.22, range 4 to 45 years ). MPI was measured again on 3 days and 1 month after closure of ASD. Change in the study group was assessed and compared to the control subjects with structurally normal hearts. A complete 2-dimensional and Doppler echocardiographic examination was performed in all study groups. Results 1) The isovolumic relaxation and isovolumic contraction times [respectively(77.59 ± 14.39)ms vs (60.93 ±12.94)ms, P<0.0001;(28.28 ±10.88)ms vs (23.64 ±9.01)ms, P=0.027] were prolonged, and ejection time [(260.65 ±21.86 )ms vs (271.85 ± 21.92)ms, P=0.033] was shortened in patients with ASD compared with that in control subjects, resulting in a marked increase in the MPI(0.40 ± 0.07 vs 0.31 ± 0.05, P<0.0001) from normal values;2) by Pearson's correlations, the MPI had no correlation with heart rate and blood pressure in control subjects and patients with ASD, but it correlated positively with age in patients with ASD;3) by Pearson's correlations, the MPI correlated positively with the diameter of ASD and pulmonary artery pressure;4) after transcatheter closure of ASD, the MPI decreased markedly. Conclusions 1) MPI is a conceptually new, simple, and reproducible Doppler index in patients with ASD;2) MPI is free from the effect of age, heart rate and blood pressure;(3) MPI appears to be relatively dependent on changes in the diameter of ASD and pulmonary artery pressure;4) the right ventricular function was improved after transcatheter closure of ASD.(J Geriatr Cardiol 2007;4:220-224.)
文摘目的探讨多模态超声心动图对肺动脉高压患者右心功能的诊断效能。方法选取2022年1月至2023年8月于金华市中心医院就诊的80例肺动脉高压患者纳入观察组,根据患者的肺动脉收缩压将其分为轻度组[40~50mmHg(1mmHg=0.133kPa),36例]、中度组(51~70mmHg,20例)和重度组(>70mmHg,24例);选取同期健康体检者80名纳入对照组,所有受试者均进行多模态超声心动图检测,对比其超声检查相关数据,评估多模态超声心动图对肺动脉高压患者右室收缩功能的诊断效能。结果观察组患者的右室舒张末期容积(right ventricular end diastolic volume,RVEDV)、右室收缩末期容积(right ventricular end systolic volume,RVESV)、右室整体无效做功(right ventricular global waste work,RVGWW)均显著高于对照组,右室每搏输出量(right ventricular stroke volume,RVSV)、右室射血分数(right ventrical ejection fraction,RVEF)、三尖瓣环收缩期位移(tricuspid annular plane systolic excusion,TAPSE)、整体纵向应变(global longitudinal strain,GLS)、右室整体做功效率(right ventricular global work efficiency,RVGWE)、右室整体做功指数(right ventricular global work index,RVGWI)、右室整体有效做功(right ventricular global constructive work,RVGCW)均显著低于对照组(P<0.05)。重度组患者的RVEDV、RVESV及RVGWW均显著高于中度组、轻度组,RVSV、RVEF、RVGWE、RVGWI、RVGCW均显著低于中度组、轻度组(P<0.05)。TAPSE、GLS、RVSV、RVEF、RVGWI五项联合诊断肺动脉高压患者右心功能的曲线下面积为0.911,敏感度为92.23%,特异性为96.45%。结论多模态超声心动图能有效评价肺动脉高压患者的右室收缩功能,值得临床推广应用。
文摘Background： To determine the influence of right ventricular function in patients with constrictive pericarditis （CP） undergoing surgery and to compare the outcomes of patients who received surgery with those managed medically. Methods： Patients with the diagnosis of CP and healthy volunteers were recruited from January 2006 to November 2011. Patients with CP chose to either receive pericardiectomy or medical management. Echocardiographic measurements were performed to evaluate heart function, and survival was recorded. Results： A total of 58 patients with CP （36 received pericardiectomy, 22 managed medically）, and 43 healthy volunteers were included. CP patients who received surgery had a higher survival rate than those managed medically （P = 0.003）, and higher st, rvival was also seen in the subgroup of CP patients with severely impaired right systolic function. Albumin level, left ventricular end-diastolic dimension, and tricuspid regurgitation velocity were associated with survival in CP patients who received surgery. Conclusions： Preoperative right heart function does not affect surgical outcomes. Patients with severely impaired preoperative right systolic function obtain a greater survival advantage with surgery than with medical treatment.
