[Objectives]To optimize the processing technology for roasted licorice with water.[Methods]Through the orthogonal experimental design,taking the water added,moistening time,frying temperature and frying time as the fa...[Objectives]To optimize the processing technology for roasted licorice with water.[Methods]Through the orthogonal experimental design,taking the water added,moistening time,frying temperature and frying time as the factors,and the content of glycyrrhizin and glycyrrhizic acid as the evaluation index,the processing technology for roasted licorice with water was optimized.[Results]The best processing technology of licorice was as follows:Pure licorice slices were mixed with water and moistened for 3 h,and then fried at 160℃for 6 min.20 kg of water was added to every 100 kg of licorice.[Conclusions]The best processing technology for roasted licorice with water was established,laying a foundation for the research and application of roasted licorice with water and its preparation.展开更多
Objective: To observe the alteration of QT dispersion(QTd) and QTc dispersion(QTcd) in hemodialysis patients after oral administration of Zhigancao Decoction(炙甘草汤,Roasted Licorice Decoction,RLD).Methods: T...Objective: To observe the alteration of QT dispersion(QTd) and QTc dispersion(QTcd) in hemodialysis patients after oral administration of Zhigancao Decoction(炙甘草汤,Roasted Licorice Decoction,RLD).Methods: To investigate the alteration of QTd and QTcd in 68 routine hemodialysis patients before and after hemodialysis with 12-lead electrocardiogram(ECG) after orally administrated RLD for 4 weeks.Blood was also taken for measurement of plasma electrolytes,liver function,renal function,hemoglobin(Hgb) and hematocrit(HCT).Results: After hemodialysis,QTd and QTcd were prolonged evidently; the difference was significant between before and after hemodialysis(P〈0.05).After RLD orally administrated for 4 weeks,QTd and QTcd only slightly increased after dialysis compared with pre-dialysis(P〉0.05).The QTd and QTcd of the post-therapy-post-dialysis decreased significantly compared with the pre-therapy-post-dialysis(P〈0.05).There were no other significant changes in other variables(post-therapy-pre-dialysis vs.pre-therapy-pre-dialysis,or post-therapy-post-dialysis vs.pre-therapy-post-dialysis; P〉0.05).After therapy,the number of patients with supraventricular arrhythmia,occasional ventricular premature beat and multiple ventricular premature beat were decreased from 15 to 4,10 to 2 and 7 to 1,respectively.Conclusion: RLD therapy not only lowered the increased QTd and QTcd after hemodialysis,but also displayed a safety profile.展开更多
文摘[Objectives]To optimize the processing technology for roasted licorice with water.[Methods]Through the orthogonal experimental design,taking the water added,moistening time,frying temperature and frying time as the factors,and the content of glycyrrhizin and glycyrrhizic acid as the evaluation index,the processing technology for roasted licorice with water was optimized.[Results]The best processing technology of licorice was as follows:Pure licorice slices were mixed with water and moistened for 3 h,and then fried at 160℃for 6 min.20 kg of water was added to every 100 kg of licorice.[Conclusions]The best processing technology for roasted licorice with water was established,laying a foundation for the research and application of roasted licorice with water and its preparation.
基金Supported by the National Natural Science Foundation of China(No.81374039)
文摘Objective: To observe the alteration of QT dispersion(QTd) and QTc dispersion(QTcd) in hemodialysis patients after oral administration of Zhigancao Decoction(炙甘草汤,Roasted Licorice Decoction,RLD).Methods: To investigate the alteration of QTd and QTcd in 68 routine hemodialysis patients before and after hemodialysis with 12-lead electrocardiogram(ECG) after orally administrated RLD for 4 weeks.Blood was also taken for measurement of plasma electrolytes,liver function,renal function,hemoglobin(Hgb) and hematocrit(HCT).Results: After hemodialysis,QTd and QTcd were prolonged evidently; the difference was significant between before and after hemodialysis(P〈0.05).After RLD orally administrated for 4 weeks,QTd and QTcd only slightly increased after dialysis compared with pre-dialysis(P〉0.05).The QTd and QTcd of the post-therapy-post-dialysis decreased significantly compared with the pre-therapy-post-dialysis(P〈0.05).There were no other significant changes in other variables(post-therapy-pre-dialysis vs.pre-therapy-pre-dialysis,or post-therapy-post-dialysis vs.pre-therapy-post-dialysis; P〉0.05).After therapy,the number of patients with supraventricular arrhythmia,occasional ventricular premature beat and multiple ventricular premature beat were decreased from 15 to 4,10 to 2 and 7 to 1,respectively.Conclusion: RLD therapy not only lowered the increased QTd and QTcd after hemodialysis,but also displayed a safety profile.