Background: The robustness is a measurement of an analytical chemical method and its ability to contain unaffected by little with deliberate variation of analytical chemical method parameters. The analytical chemical ...Background: The robustness is a measurement of an analytical chemical method and its ability to contain unaffected by little with deliberate variation of analytical chemical method parameters. The analytical chemical method variation parameters are based on pH variability of buffer solution of mobile phase, organic ratio composition changes, stationary phase (column) manufacture, brand name and lot number variation;flow rate variation and temperature variation of chromatographic system. The analytical chemical method for assay of Atropine Sulfate conducted for robustness evaluation. The typical variation considered for mobile phase organic ratio change, change of pH, change of temperature, change of flow rate, change of column etc. Purpose: The aim of this study is to develop a cost effective, short run time and robust analytical chemical method for the assay quantification of Atropine in Pharmaceutical Ophthalmic Solution. This will help to make analytical decisions quickly for research and development scientists as well as will help with quality control product release for patient consumption. This analytical method will help to meet the market demand through quick quality control test of Atropine Ophthalmic Solution and it is very easy for maintaining (GDP) good documentation practices within the shortest period of time. Method: HPLC method has been selected for developing superior method to Compendial method. Both the compendial HPLC method and developed HPLC method was run into the same HPLC system to prove the superiority of developed method. Sensitivity, precision, reproducibility, accuracy parameters were considered for superiority of method. Mobile phase ratio change, pH of buffer solution, change of stationary phase temperature, change of flow rate and change of column were taken into consideration for robustness study of the developed method. Results: The limit of quantitation (LOQ) of developed method was much low than the compendial method. The % RSD for the six sample assay of developed method was 0.4% where the % RSD of the compendial method was 1.2%. The reproducibility between two analysts was 100.4% for developed method on the contrary the compendial method was 98.4%.展开更多
Hidden capacity,concealment,security,and robustness are essential indicators of hiding algorithms.Currently,hiding algorithms tend to focus on algorithmic capacity,concealment,and security but often overlook the robus...Hidden capacity,concealment,security,and robustness are essential indicators of hiding algorithms.Currently,hiding algorithms tend to focus on algorithmic capacity,concealment,and security but often overlook the robustness of the algorithms.In practical applications,the container can suffer from damage caused by noise,cropping,and other attacks during transmission,resulting in challenging or even impossible complete recovery of the secret image.An image hiding algorithm based on dynamic region attention in the multi-scale wavelet domain is proposed to address this issue and enhance the robustness of hiding algorithms.In this proposed algorithm,a secret image of size 256×256 is first decomposed using an eight-level Haar wavelet transform.The wavelet transform generates one coefficient in the approximation component and twenty-four detail bands,which are then embedded into the carrier image via a hiding network.During the recovery process,the container image is divided into four non-overlapping parts,each employed to reconstruct a low-resolution secret image.These lowresolution secret images are combined using densemodules to obtain a high-quality secret image.The experimental results showed that even under destructive attacks on the container image,the proposed algorithm is successful in recovering a high-quality secret image,indicating that the algorithm exhibits a high degree of robustness against various attacks.The proposed algorithm effectively addresses the robustness issue by incorporating both spatial and channel attention mechanisms in the multi-scale wavelet domain,making it suitable for practical applications.In conclusion,the image hiding algorithm introduced in this study offers significant improvements in robustness compared to existing algorithms.Its ability to recover high-quality secret images even in the presence of destructive attacksmakes it an attractive option for various applications.Further research and experimentation can explore the algorithm’s performance under different scenarios and expand its potential applications.展开更多
With the widespread use of machine learning(ML)technology,the operational efficiency and responsiveness of power grids have been significantly enhanced,allowing smart grids to achieve high levels of automation and int...With the widespread use of machine learning(ML)technology,the operational efficiency and responsiveness of power grids have been significantly enhanced,allowing smart grids to achieve high levels of automation and intelligence.However,tree ensemble models commonly used in smart grids are vulnerable to adversarial attacks,making it urgent to enhance their robustness.To address this,we propose a robustness enhancement method that incorporates physical constraints into the node-splitting decisions of tree ensembles.Our algorithm improves robustness by developing a dataset of adversarial examples that comply with physical laws,ensuring training data accurately reflects possible attack scenarios while adhering to physical rules.In our experiments,the proposed method increased robustness against adversarial attacks by 100%when applied to real grid data under physical constraints.These results highlight the advantages of our method in maintaining efficient and secure operation of smart grids under adversarial conditions.展开更多
Utilizing machine learning techniques for data-driven diagnosis of high temperature PEM fuel cells is beneficial and meaningful to the system durability. Nevertheless, ensuring the robustness of diagnosis remains a cr...Utilizing machine learning techniques for data-driven diagnosis of high temperature PEM fuel cells is beneficial and meaningful to the system durability. Nevertheless, ensuring the robustness of diagnosis remains a critical and challenging task in real application. To enhance the robustness of diagnosis and achieve a more thorough evaluation of diagnostic performance, a robust diagnostic procedure based on electrochemical impedance spectroscopy (EIS) and a new method for evaluation of the diagnosis robustness was proposed and investigated in this work. To improve the diagnosis robustness: (1) the degradation mechanism of different faults in the high temperature PEM fuel cell was first analyzed via the distribution of relaxation time of EIS to determine the equivalent circuit model (ECM) with better interpretability, simplicity and accuracy;(2) the feature extraction was implemented on the identified parameters of the ECM and extra attention was paid to distinguishing between the long-term normal degradation and other faults;(3) a Siamese Network was adopted to get features with higher robustness in a new embedding. The diagnosis was conducted using 6 classic classification algorithms—support vector machine (SVM), K-nearest neighbor (KNN), logistic regression (LR), decision tree (DT), random forest (RF), and Naive Bayes employing a dataset comprising a total of 1935 collected EIS. To evaluate the robustness of trained models: (1) different levels of errors were added to the features for performance evaluation;(2) a robustness coefficient (Roubust_C) was defined for a quantified and explicit evaluation of the diagnosis robustness. The diagnostic models employing the proposed feature extraction method can not only achieve the higher performance of around 100% but also higher robustness for diagnosis models. Despite the initial performance being similar, the KNN demonstrated a superior robustness after feature selection and re-embedding by triplet-loss method, which suggests the necessity of robustness evaluation for the machine learning models and the effectiveness of the defined robustness coefficient. This work hopes to give new insights to the robust diagnosis of high temperature PEM fuel cells and more comprehensive performance evaluation of the data-driven method for diagnostic application.展开更多
利用电磁阻尼单元代替经典调谐质量阻尼器中的黏性阻尼单元,形成一种具有结构减振功能的新型电磁谐振式调谐质量阻尼器(electromagnetic shunt tuned mass damper,EMS-TMD)。为进一步提升阻尼器的减振性能和鲁棒性,设计了双重电磁谐振...利用电磁阻尼单元代替经典调谐质量阻尼器中的黏性阻尼单元,形成一种具有结构减振功能的新型电磁谐振式调谐质量阻尼器(electromagnetic shunt tuned mass damper,EMS-TMD)。为进一步提升阻尼器的减振性能和鲁棒性,设计了双重电磁谐振式调谐质量阻尼器(DEMS-TMD)减振方案。依据达朗伯定理,建立地震作用下DEMS-TMD与单自由度结构耦合振动系统的动力学模型。利用蒙特卡洛-模式搜索法数值优化方法,以主结构位移的动力放大系数最大值最小为目标函数,优化得到DEMS-TMD的结构频率比、电子频率比、电磁阻尼比和机电耦合系数的最优参数,为减振参数设计提供理论指导。通过频域和时域两种方法仿真分析了DEMSTMD对结构的减振性能。结果表明:在频域分析中,DEMS-TMD的主结构位移峰值和频响面积均优于传统并联双调谐质量阻尼器(double tuned mass damper,DTMD);在时域分析中,DEMS-TMD对结构位移、加速度峰值和均方根的减振性能均优于传统DTMD,有效地提高了对结构的减振效果。展开更多
文摘Background: The robustness is a measurement of an analytical chemical method and its ability to contain unaffected by little with deliberate variation of analytical chemical method parameters. The analytical chemical method variation parameters are based on pH variability of buffer solution of mobile phase, organic ratio composition changes, stationary phase (column) manufacture, brand name and lot number variation;flow rate variation and temperature variation of chromatographic system. The analytical chemical method for assay of Atropine Sulfate conducted for robustness evaluation. The typical variation considered for mobile phase organic ratio change, change of pH, change of temperature, change of flow rate, change of column etc. Purpose: The aim of this study is to develop a cost effective, short run time and robust analytical chemical method for the assay quantification of Atropine in Pharmaceutical Ophthalmic Solution. This will help to make analytical decisions quickly for research and development scientists as well as will help with quality control product release for patient consumption. This analytical method will help to meet the market demand through quick quality control test of Atropine Ophthalmic Solution and it is very easy for maintaining (GDP) good documentation practices within the shortest period of time. Method: HPLC method has been selected for developing superior method to Compendial method. Both the compendial HPLC method and developed HPLC method was run into the same HPLC system to prove the superiority of developed method. Sensitivity, precision, reproducibility, accuracy parameters were considered for superiority of method. Mobile phase ratio change, pH of buffer solution, change of stationary phase temperature, change of flow rate and change of column were taken into consideration for robustness study of the developed method. Results: The limit of quantitation (LOQ) of developed method was much low than the compendial method. The % RSD for the six sample assay of developed method was 0.4% where the % RSD of the compendial method was 1.2%. The reproducibility between two analysts was 100.4% for developed method on the contrary the compendial method was 98.4%.
基金partly supported by the National Natural Science Foundation of China(Jianhua Wu,Grant No.62041106).
文摘Hidden capacity,concealment,security,and robustness are essential indicators of hiding algorithms.Currently,hiding algorithms tend to focus on algorithmic capacity,concealment,and security but often overlook the robustness of the algorithms.In practical applications,the container can suffer from damage caused by noise,cropping,and other attacks during transmission,resulting in challenging or even impossible complete recovery of the secret image.An image hiding algorithm based on dynamic region attention in the multi-scale wavelet domain is proposed to address this issue and enhance the robustness of hiding algorithms.In this proposed algorithm,a secret image of size 256×256 is first decomposed using an eight-level Haar wavelet transform.The wavelet transform generates one coefficient in the approximation component and twenty-four detail bands,which are then embedded into the carrier image via a hiding network.During the recovery process,the container image is divided into four non-overlapping parts,each employed to reconstruct a low-resolution secret image.These lowresolution secret images are combined using densemodules to obtain a high-quality secret image.The experimental results showed that even under destructive attacks on the container image,the proposed algorithm is successful in recovering a high-quality secret image,indicating that the algorithm exhibits a high degree of robustness against various attacks.The proposed algorithm effectively addresses the robustness issue by incorporating both spatial and channel attention mechanisms in the multi-scale wavelet domain,making it suitable for practical applications.In conclusion,the image hiding algorithm introduced in this study offers significant improvements in robustness compared to existing algorithms.Its ability to recover high-quality secret images even in the presence of destructive attacksmakes it an attractive option for various applications.Further research and experimentation can explore the algorithm’s performance under different scenarios and expand its potential applications.
基金This work was supported by Natural Science Foundation of China(Nos.62303126,62362008,62066006,authors Zhenyong Zhang and Bin Hu,https://www.nsfc.gov.cn/,accessed on 25 July 2024)Guizhou Provincial Science and Technology Projects(No.ZK[2022]149,author Zhenyong Zhang,https://kjt.guizhou.gov.cn/,accessed on 25 July 2024)+1 种基金Guizhou Provincial Research Project(Youth)forUniversities(No.[2022]104,author Zhenyong Zhang,https://jyt.guizhou.gov.cn/,accessed on 25 July 2024)GZU Cultivation Project of NSFC(No.[2020]80,author Zhenyong Zhang,https://www.gzu.edu.cn/,accessed on 25 July 2024).
文摘With the widespread use of machine learning(ML)technology,the operational efficiency and responsiveness of power grids have been significantly enhanced,allowing smart grids to achieve high levels of automation and intelligence.However,tree ensemble models commonly used in smart grids are vulnerable to adversarial attacks,making it urgent to enhance their robustness.To address this,we propose a robustness enhancement method that incorporates physical constraints into the node-splitting decisions of tree ensembles.Our algorithm improves robustness by developing a dataset of adversarial examples that comply with physical laws,ensuring training data accurately reflects possible attack scenarios while adhering to physical rules.In our experiments,the proposed method increased robustness against adversarial attacks by 100%when applied to real grid data under physical constraints.These results highlight the advantages of our method in maintaining efficient and secure operation of smart grids under adversarial conditions.
基金supported by the Chinese Scholarship Council(Nos.202208320055 and 202108320111)the support from the energy department of Aalborg University was acknowledged.
文摘Utilizing machine learning techniques for data-driven diagnosis of high temperature PEM fuel cells is beneficial and meaningful to the system durability. Nevertheless, ensuring the robustness of diagnosis remains a critical and challenging task in real application. To enhance the robustness of diagnosis and achieve a more thorough evaluation of diagnostic performance, a robust diagnostic procedure based on electrochemical impedance spectroscopy (EIS) and a new method for evaluation of the diagnosis robustness was proposed and investigated in this work. To improve the diagnosis robustness: (1) the degradation mechanism of different faults in the high temperature PEM fuel cell was first analyzed via the distribution of relaxation time of EIS to determine the equivalent circuit model (ECM) with better interpretability, simplicity and accuracy;(2) the feature extraction was implemented on the identified parameters of the ECM and extra attention was paid to distinguishing between the long-term normal degradation and other faults;(3) a Siamese Network was adopted to get features with higher robustness in a new embedding. The diagnosis was conducted using 6 classic classification algorithms—support vector machine (SVM), K-nearest neighbor (KNN), logistic regression (LR), decision tree (DT), random forest (RF), and Naive Bayes employing a dataset comprising a total of 1935 collected EIS. To evaluate the robustness of trained models: (1) different levels of errors were added to the features for performance evaluation;(2) a robustness coefficient (Roubust_C) was defined for a quantified and explicit evaluation of the diagnosis robustness. The diagnostic models employing the proposed feature extraction method can not only achieve the higher performance of around 100% but also higher robustness for diagnosis models. Despite the initial performance being similar, the KNN demonstrated a superior robustness after feature selection and re-embedding by triplet-loss method, which suggests the necessity of robustness evaluation for the machine learning models and the effectiveness of the defined robustness coefficient. This work hopes to give new insights to the robust diagnosis of high temperature PEM fuel cells and more comprehensive performance evaluation of the data-driven method for diagnostic application.
文摘利用电磁阻尼单元代替经典调谐质量阻尼器中的黏性阻尼单元,形成一种具有结构减振功能的新型电磁谐振式调谐质量阻尼器(electromagnetic shunt tuned mass damper,EMS-TMD)。为进一步提升阻尼器的减振性能和鲁棒性,设计了双重电磁谐振式调谐质量阻尼器(DEMS-TMD)减振方案。依据达朗伯定理,建立地震作用下DEMS-TMD与单自由度结构耦合振动系统的动力学模型。利用蒙特卡洛-模式搜索法数值优化方法,以主结构位移的动力放大系数最大值最小为目标函数,优化得到DEMS-TMD的结构频率比、电子频率比、电磁阻尼比和机电耦合系数的最优参数,为减振参数设计提供理论指导。通过频域和时域两种方法仿真分析了DEMSTMD对结构的减振性能。结果表明:在频域分析中,DEMS-TMD的主结构位移峰值和频响面积均优于传统并联双调谐质量阻尼器(double tuned mass damper,DTMD);在时域分析中,DEMS-TMD对结构位移、加速度峰值和均方根的减振性能均优于传统DTMD,有效地提高了对结构的减振效果。
