BACKGROUND The global burden of hepatitis D virus(HDV)infection represents a major medical challenge and a public health crisis worldwide.However,there is a lack of accurate data on the epidemiology and risk factors f...BACKGROUND The global burden of hepatitis D virus(HDV)infection represents a major medical challenge and a public health crisis worldwide.However,there is a lack of accurate data on the epidemiology and risk factors for HDV.Hepatitis B virus(HBV)and HDV coinfection causes the most severe form of viral hepatitis,leading to a higher cumulative incidence of liver-related events compared with HBV monoinfection,including the need for liver transplantation and death.AIM To investigate the epidemiology,natural history,risk factors and clinical management of HBV and HDV coinfection in Romanian patients.METHODS This prospective study was conducted between January and July 2022 in six tertiary gastroenterology and hepatology referral centres in Romania.All consecutive adults admitted for any gastroenterology diagnosis who were HBV-positive were enrolled.Patients with acute hepatitis or incomplete data were excluded.Of the 25390 individuals who presented with any type of gastroenterology diagnosis during the study period,963 met the inclusion criteria.Testing for anti-HDV antibodies and HDV RNA was performed for all participants.Demographic and risk factor data were collected by investigators using medical charts and patient questionnaires.All data were stored in an anonymized online database during the study.RESULTS The prevalence of HBV was 3.8%;among these patients,the prevalence of HBV/HDV coinfection was 33.1%.The median age of the study population was 54.0 years,and it consisted of 55.1%men.A higher prevalence of HBV/HDV coinfection was observed in patients 50–69 years old.Patients with HBV/HDV coinfection were significantly older than those with HBV monoinfection(P=0.03).Multivariate multiple regression analysis identified female gender(P=0.0006),imprisonment(P<0.0001),older age at diagnosis(P=0.01)and sexual contact with persons with known viral hepatitis(P=0.0003)as significant risk factors for HDV.CONCLUSION This study shows that HDV infection among those with HBV remains endemic in Romania and updates our understanding of HDV epidemiology and associated risk factors.It emphasizes the need for systematic screening for HDV infection and collaborative initiatives for controlling and preventing HBV and HDV infection.展开更多
Romania’s innovation revolution has led to a thriving startup ecosystem, with UiPath’s unicorn journey as a standout success. The country’s focus on software development has positioned it as a leading destination f...Romania’s innovation revolution has led to a thriving startup ecosystem, with UiPath’s unicorn journey as a standout success. The country’s focus on software development has positioned it as a leading destination for outsourcing, driving economic growth, and creating job opportunities. Accelerator programs and funding initiatives have further fueled the startup ecosystem’s growth, providing support and resources for aspiring entrepreneurs. With a skilled workforce, favorable cost-to-quality ratio, and geographic advantages, Romania has become a hub for innovation and technology. The software development sector’s impact on the national economy is evident, contributing to GDP growth, export revenues, and attracting foreign direct investment.展开更多
AIM:To describe the relationship between vitamin D levels and inflammatory bowel disease(IBD)characteristics in northeastern Romanian patients.METHODS:This was a prospective study of 47 consecutive IBD patients admitt...AIM:To describe the relationship between vitamin D levels and inflammatory bowel disease(IBD)characteristics in northeastern Romanian patients.METHODS:This was a prospective study of 47 consecutive IBD patients admitted to The Institute of Gastroenterology and Hepatology in Iasi,Romania between March 2011 and June 2012.The diagnosis of IBD was established based on endoscopic,histologic and radiologic findings.Demographic data,disease characteristics,ongoing treatments and biological parameters of patients(including markers of inflammation:C-reactive protein level,fibrinogen level,and erythrocyte sedimentation rate)were recorded.Serum vitamin D levels were measured and compared with age-and sexmatched healthy volunteers from the same geographic area.Vitamin D levels were defined as sufficient(>30ng/mL),insufficient(20-30 ng/mL),or severely defi-cient(<20 ng/mL).RESULTS:Thirty-three of the IBD patients included in this study had ulcerative colitis(UC)and 14 had Crohn’s disease(CD).Only 24%of the UC patients and 21%of the CD patients had sufficient vitamin D levels.The vitamin D levels were significantly lower in the CD patients with moderate to severe disease activity compared to the CD patients in remission or with mild disease activity(16±6 ng/mL vs 26±7 ng/mL;16±6 ng/mL vs 31±9 ng/mL,respectively,P<0.05).Vitamin D levels in the UC patients were not influenced by disease activity and no correlation was observed with the inflammation markers tested(C-reactive protein,fibrinogen,and erythrocyte sedimentation rate).No association was observed between vitamin D levels and smoking status or ongoing medication(5ASA,steroids,and anti-TNFα).Newly diagnosed IBD patients had lower vitamin D levels than patients with established cases,though these differences were not significant(UC:22±9 ng/mL vs 26±12 ng/mL;CD:18±6 ng/mL vs 27±11 ng/mL,respectively).Although no association was found between the season during which the visit was scheduled and vitamin D levels,the UC patients assessed during the winter tended to have lower levels than those assessed during the summer(22±9 ng/mL vs 28±13 ng/mL,respectively).CONCLUSION:Vitamin D levels are significantly reduced in IBD patients in northeastern Romania,with the lowest levels occurring in CD patients with moderate to severe disease activity.展开更多
Malaria is a major problem for European travelers to endemic regions.In Romania during 1980-2007 approximately 20 imported cases were detected annually.The aim of our short communication is to present 2 interesting ca...Malaria is a major problem for European travelers to endemic regions.In Romania during 1980-2007 approximately 20 imported cases were detected annually.The aim of our short communication is to present 2 interesting cases of imported malaria detected in Western Romania.The first patienl was a 20-year female who traveled to India and acquired an infection with Plasmodium vivax(P.vivax).The second patient,a 60-year female,contracted an infection with Plasmodium falciparum(P.falciparum) during a trip to Ghana:the evolution of the disease was severe with many complications and the patient finally died.The cases presented revealed the difficulties in establishing a correct diagnosis of malaria in a non-endemic country, consequences of an incomplete taken anamnesis.Travel history should always represent a mandatory part of a well conducted investigation.At the same time,we must underline the importance of a correct and complete prophylaxis prior to every departure to tropical countries.展开更多
Romania is one of the European countries most frequently affected by natural hazards due to its position within the alpine orogenic system and against the main atmospheric pressure centres.Hence the impact of exogenou...Romania is one of the European countries most frequently affected by natural hazards due to its position within the alpine orogenic system and against the main atmospheric pressure centres.Hence the impact of exogenous factors that trigger strong earthquakes with several epicentres, and of exogenous or climate-driven factors with extreme climatic phenomena causing frequent floods, mass movements, soil erosion, droughts, hailstorms and strong winds. This paper deals mainly with natural disasters cased by the variability of climatic conditions (mostly by precipitations) in the years 1996 and 1997, their temporal and spatial distributions and the way they affected human life. In point of rainfall distribution and the ensuing natural hazards, the mentioned period shows two distinct intervals: December, 1996-March 1997 (mass movements) and June-August, 1997 (floods, hailstorm,Strong wind,landslides, soil erosion).展开更多
ZTE, a leading global provide of telecommunications equipment and network sulutions, announced on May 29, 2008 that it has been selected by Zapp, Romania’s fourth largest mobile operator, to roll-out a WCDMA/HSDPA co...ZTE, a leading global provide of telecommunications equipment and network sulutions, announced on May 29, 2008 that it has been selected by Zapp, Romania’s fourth largest mobile operator, to roll-out a WCDMA/HSDPA commercial network. This deal reinforces ZTE position in Europe. Zapp plans on launching its 3G commercial services in early autumn 2008 and the network should be completed by 2011.展开更多
September in golden autumn symbolizes harvest and hope.At the invitation of the New Silk Road Institute,Prague of the Czech Republic,Institute for Foreign Affairs and Trade of Hungary and Romania China Chamber of Comm...September in golden autumn symbolizes harvest and hope.At the invitation of the New Silk Road Institute,Prague of the Czech Republic,Institute for Foreign Affairs and Trade of Hungary and Romania China Chamber of Commerce and Industry,Mme.展开更多
On September 23,2019,the Silk Road Community Building Initiative was launched as part of the joint efforts by China and Romania to build the Belt and Road."The Belt and Road is an ambitious initiative that will b...On September 23,2019,the Silk Road Community Building Initiative was launched as part of the joint efforts by China and Romania to build the Belt and Road."The Belt and Road is an ambitious initiative that will bring prosperity to the world and a new economic impetus in Romania,"said Minister of Economy Nicolae Badalau at the launching ceremony held in the historical Ghica Palace in downtown Bucharest.He also voiced support for the ensuing cooperation at the local level.展开更多
Distinguished former Prime Minister Mr.Peter Roman,Distinguished Minister Mr.Niculae Badalau,Distinguished Mr.&Mrs.Bartha,Ladies and gentlemen,dear friends,It’s my great delight to attend the launching ceremony o...Distinguished former Prime Minister Mr.Peter Roman,Distinguished Minister Mr.Niculae Badalau,Distinguished Mr.&Mrs.Bartha,Ladies and gentlemen,dear friends,It’s my great delight to attend the launching ceremony of the Silk Road Community Building Initiative in Romania,which is a major event to enhance the mutual understanding and trust,promote people-to-people connectivity as well as consolidate the foundation of the Belt and Road cooperation between China and Romania.展开更多
Given the institutional similarities between Romania and China in history,its experience in the field of foreign language education reform in colleges and universities can be used for reference in the reform of foreig...Given the institutional similarities between Romania and China in history,its experience in the field of foreign language education reform in colleges and universities can be used for reference in the reform of foreign language teaching of higher education in China.With the help of Citespace,this paper presents a visual statistical analysis of 47 SSCI international journal articles on foreign language reform in Romanian universities and gives some suggestions on foreign language education reform in Chinese universities from four aspects:teaching environment,content,technology and cooperation.展开更多
文摘BACKGROUND The global burden of hepatitis D virus(HDV)infection represents a major medical challenge and a public health crisis worldwide.However,there is a lack of accurate data on the epidemiology and risk factors for HDV.Hepatitis B virus(HBV)and HDV coinfection causes the most severe form of viral hepatitis,leading to a higher cumulative incidence of liver-related events compared with HBV monoinfection,including the need for liver transplantation and death.AIM To investigate the epidemiology,natural history,risk factors and clinical management of HBV and HDV coinfection in Romanian patients.METHODS This prospective study was conducted between January and July 2022 in six tertiary gastroenterology and hepatology referral centres in Romania.All consecutive adults admitted for any gastroenterology diagnosis who were HBV-positive were enrolled.Patients with acute hepatitis or incomplete data were excluded.Of the 25390 individuals who presented with any type of gastroenterology diagnosis during the study period,963 met the inclusion criteria.Testing for anti-HDV antibodies and HDV RNA was performed for all participants.Demographic and risk factor data were collected by investigators using medical charts and patient questionnaires.All data were stored in an anonymized online database during the study.RESULTS The prevalence of HBV was 3.8%;among these patients,the prevalence of HBV/HDV coinfection was 33.1%.The median age of the study population was 54.0 years,and it consisted of 55.1%men.A higher prevalence of HBV/HDV coinfection was observed in patients 50–69 years old.Patients with HBV/HDV coinfection were significantly older than those with HBV monoinfection(P=0.03).Multivariate multiple regression analysis identified female gender(P=0.0006),imprisonment(P<0.0001),older age at diagnosis(P=0.01)and sexual contact with persons with known viral hepatitis(P=0.0003)as significant risk factors for HDV.CONCLUSION This study shows that HDV infection among those with HBV remains endemic in Romania and updates our understanding of HDV epidemiology and associated risk factors.It emphasizes the need for systematic screening for HDV infection and collaborative initiatives for controlling and preventing HBV and HDV infection.
文摘Romania’s innovation revolution has led to a thriving startup ecosystem, with UiPath’s unicorn journey as a standout success. The country’s focus on software development has positioned it as a leading destination for outsourcing, driving economic growth, and creating job opportunities. Accelerator programs and funding initiatives have further fueled the startup ecosystem’s growth, providing support and resources for aspiring entrepreneurs. With a skilled workforce, favorable cost-to-quality ratio, and geographic advantages, Romania has become a hub for innovation and technology. The software development sector’s impact on the national economy is evident, contributing to GDP growth, export revenues, and attracting foreign direct investment.
基金Supported by A Grant from the Managing Authority of the Sectorial Operational Program for Human Resources Development,POSDRU 107/1.5/S/78702
文摘AIM:To describe the relationship between vitamin D levels and inflammatory bowel disease(IBD)characteristics in northeastern Romanian patients.METHODS:This was a prospective study of 47 consecutive IBD patients admitted to The Institute of Gastroenterology and Hepatology in Iasi,Romania between March 2011 and June 2012.The diagnosis of IBD was established based on endoscopic,histologic and radiologic findings.Demographic data,disease characteristics,ongoing treatments and biological parameters of patients(including markers of inflammation:C-reactive protein level,fibrinogen level,and erythrocyte sedimentation rate)were recorded.Serum vitamin D levels were measured and compared with age-and sexmatched healthy volunteers from the same geographic area.Vitamin D levels were defined as sufficient(>30ng/mL),insufficient(20-30 ng/mL),or severely defi-cient(<20 ng/mL).RESULTS:Thirty-three of the IBD patients included in this study had ulcerative colitis(UC)and 14 had Crohn’s disease(CD).Only 24%of the UC patients and 21%of the CD patients had sufficient vitamin D levels.The vitamin D levels were significantly lower in the CD patients with moderate to severe disease activity compared to the CD patients in remission or with mild disease activity(16±6 ng/mL vs 26±7 ng/mL;16±6 ng/mL vs 31±9 ng/mL,respectively,P<0.05).Vitamin D levels in the UC patients were not influenced by disease activity and no correlation was observed with the inflammation markers tested(C-reactive protein,fibrinogen,and erythrocyte sedimentation rate).No association was observed between vitamin D levels and smoking status or ongoing medication(5ASA,steroids,and anti-TNFα).Newly diagnosed IBD patients had lower vitamin D levels than patients with established cases,though these differences were not significant(UC:22±9 ng/mL vs 26±12 ng/mL;CD:18±6 ng/mL vs 27±11 ng/mL,respectively).Although no association was found between the season during which the visit was scheduled and vitamin D levels,the UC patients assessed during the winter tended to have lower levels than those assessed during the summer(22±9 ng/mL vs 28±13 ng/mL,respectively).CONCLUSION:Vitamin D levels are significantly reduced in IBD patients in northeastern Romania,with the lowest levels occurring in CD patients with moderate to severe disease activity.
文摘Malaria is a major problem for European travelers to endemic regions.In Romania during 1980-2007 approximately 20 imported cases were detected annually.The aim of our short communication is to present 2 interesting cases of imported malaria detected in Western Romania.The first patienl was a 20-year female who traveled to India and acquired an infection with Plasmodium vivax(P.vivax).The second patient,a 60-year female,contracted an infection with Plasmodium falciparum(P.falciparum) during a trip to Ghana:the evolution of the disease was severe with many complications and the patient finally died.The cases presented revealed the difficulties in establishing a correct diagnosis of malaria in a non-endemic country, consequences of an incomplete taken anamnesis.Travel history should always represent a mandatory part of a well conducted investigation.At the same time,we must underline the importance of a correct and complete prophylaxis prior to every departure to tropical countries.
文摘Romania is one of the European countries most frequently affected by natural hazards due to its position within the alpine orogenic system and against the main atmospheric pressure centres.Hence the impact of exogenous factors that trigger strong earthquakes with several epicentres, and of exogenous or climate-driven factors with extreme climatic phenomena causing frequent floods, mass movements, soil erosion, droughts, hailstorms and strong winds. This paper deals mainly with natural disasters cased by the variability of climatic conditions (mostly by precipitations) in the years 1996 and 1997, their temporal and spatial distributions and the way they affected human life. In point of rainfall distribution and the ensuing natural hazards, the mentioned period shows two distinct intervals: December, 1996-March 1997 (mass movements) and June-August, 1997 (floods, hailstorm,Strong wind,landslides, soil erosion).
文摘ZTE, a leading global provide of telecommunications equipment and network sulutions, announced on May 29, 2008 that it has been selected by Zapp, Romania’s fourth largest mobile operator, to roll-out a WCDMA/HSDPA commercial network. This deal reinforces ZTE position in Europe. Zapp plans on launching its 3G commercial services in early autumn 2008 and the network should be completed by 2011.
文摘September in golden autumn symbolizes harvest and hope.At the invitation of the New Silk Road Institute,Prague of the Czech Republic,Institute for Foreign Affairs and Trade of Hungary and Romania China Chamber of Commerce and Industry,Mme.
文摘On September 23,2019,the Silk Road Community Building Initiative was launched as part of the joint efforts by China and Romania to build the Belt and Road."The Belt and Road is an ambitious initiative that will bring prosperity to the world and a new economic impetus in Romania,"said Minister of Economy Nicolae Badalau at the launching ceremony held in the historical Ghica Palace in downtown Bucharest.He also voiced support for the ensuing cooperation at the local level.
文摘Distinguished former Prime Minister Mr.Peter Roman,Distinguished Minister Mr.Niculae Badalau,Distinguished Mr.&Mrs.Bartha,Ladies and gentlemen,dear friends,It’s my great delight to attend the launching ceremony of the Silk Road Community Building Initiative in Romania,which is a major event to enhance the mutual understanding and trust,promote people-to-people connectivity as well as consolidate the foundation of the Belt and Road cooperation between China and Romania.
基金This research is funded by Jiangsu Provincial Educational Departmant,Project No.2020SJZDA013Nanjing University of Aeronautics and Astronautics,Grant NR2021018,Poject No.1012-XAB21010.
文摘Given the institutional similarities between Romania and China in history,its experience in the field of foreign language education reform in colleges and universities can be used for reference in the reform of foreign language teaching of higher education in China.With the help of Citespace,this paper presents a visual statistical analysis of 47 SSCI international journal articles on foreign language reform in Romanian universities and gives some suggestions on foreign language education reform in Chinese universities from four aspects:teaching environment,content,technology and cooperation.