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Rosai-Dorfman disease in the spleen of a pediatric patient:A case report
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作者 Hwaseong Ryu Jae-Yeon Hwang +5 位作者 Yong-Woo Kim Tae-Un Kim Joo-Yeon Jang Su-Eun Park Eu-Jeen Yang Dong-Hoon Shin 《World Journal of Clinical Cases》 SCIE 2021年第21期6032-6040,共9页
BACKGROUND Rosai–Dorfman disease(RDD)is a rare histiocytic proliferation of unknown etiology commonly found in children and adolescents.The common manifestation of RDD is massive and painless bilateral cervical lymph... BACKGROUND Rosai–Dorfman disease(RDD)is a rare histiocytic proliferation of unknown etiology commonly found in children and adolescents.The common manifestation of RDD is massive and painless bilateral cervical lymphadenopathy with extranodal disease.While extranodal involvement in RDD is common,the spleen is an infrequent site of disease.CASE SUMMARY We report a 10-mo-old female infant with RDD presenting multiple splenic masses without cervical lymphadenopathy.She had fever,and blood tests showed leukocytosis,anemia,and elevated erythrocyte sedimentation rate and Creactive protein.Ultrasound,computed tomography,and magnetic resonance images demonstrated multiple splenic masses.Despite antibiotic therapy,her symptoms were not relived.She underwent diagnostic splenectomy and was discharged with recovery.CONCLUSION In pediatric patients with refractory infectious symptoms or hematological abnormalities,clinicians should suspect RDD,even in patients without significant lymphadenopathy. 展开更多
关键词 rosaidorfman disease Sinus histiocytosis with massive lymphadenopathy ULTRASONOGRAPHY Computed tomography Magnetic resonance imaging Case report
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