Structural and antioxidative properties of royal jelly protein by partial enzymatic hydrolysis

The objective of this study was to investigate the structural and antioxidative properties of royal jelly protein(RJP)at different degrees of hydrolysis(DH)by partial enzymatic hydrolysis. RJP was hydrolyzed by alcalase for 0 min, 15 min, 1 h, 5 h and 8 h to obtain hydrolysates at DH of 5.34%, 11.65%, 15.19%, 21.38% and 23.91%, respectively. With the increased DH, the RJP hydrolysates showed elevated antioxidative activities. The molecular weight of RJP hydrolysates was significantly decreased but their primary backbone kept unchanged. Analysis of circular dichroism spectra revealed that the enzymolysis reduced the content of α-helix but increased the contents of β-sheet, β-turn and random coil. Meanwhile, the surface hydrophobicity and fluorescence intensity of RJP hydrolysates were decreased and a red shift occurred. As the enzymolysis continued, the surface morphology of RJP was gradually changed from a sheet-like structure into microparticles. Changes in antioxidative activities and structures generally followed a DH-dependent manner, however these changes became insignificant for samples at DH beyond 20%. Taking into consideration of both effectiveness and productivity, the optimum enzymatic duration was determined at 5 h.

Battle Royale Optimization-Based Resource Scheduling Scheme for Cloud Computing Environment

Cloud computing(CC)is developing as a powerful and flexible computational structure for providing ubiquitous service to users.It receives interrelated software and hardware resources in an integrated manner distinct from the classical computational environment.The variation of software and hardware resources were combined and composed as a resource pool.The software no more resided in the single hardware environment,it can be executed on the schedule of resource pools to optimize resource consumption.Optimizing energy consumption in CC environments is the question that allows utilizing several energy conservation approaches for effective resource allocation.This study introduces a Battle Royale Optimization-based Resource Scheduling Scheme for Cloud Computing Environment(BRORSS-CCE)technique.The presented BRORSS-CCE technique majorly schedules the available resources for maximum utilization and effectual makespan.In the BRORSS-CCE technique,the BRO is a population-based algorithm where all the individuals are denoted by a soldier/player who likes to go towards the optimal place and ultimate survival.The BRORSS-CCE technique can be employed to balance the load,distribute resources based on demand and assure services to all requests.The experimental validation of the BRORSS-CCE technique is tested under distinct aspects.The experimental outcomes indicated the enhancements of the BRORSS-CCE technique over other models.

Battle Royale Optimization with Fuzzy Deep Learning for Arabic Sentiment Classification

Aspect-Based Sentiment Analysis(ABSA)on Arabic corpus has become an active research topic in recent days.ABSA refers to a fine-grained Sentiment Analysis(SA)task that focuses on the extraction of the conferred aspects and the identification of respective sentiment polarity from the provided text.Most of the prevailing Arabic ABSA techniques heavily depend upon dreary feature-engineering and pre-processing tasks and utilize external sources such as lexicons.In literature,concerning the Arabic language text analysis,the authors made use of regular Machine Learning(ML)techniques that rely on a group of rare sources and tools.These sources were used for processing and analyzing the Arabic language content like lexicons.However,an important challenge in this domain is the unavailability of sufficient and reliable resources.In this background,the current study introduces a new Battle Royale Optimization with Fuzzy Deep Learning for Arabic Aspect Based Sentiment Classification(BROFDL-AASC)technique.The aim of the presented BROFDL-AASC model is to detect and classify the sentiments in the Arabic language.In the presented BROFDL-AASC model,data pre-processing is performed at first to convert the input data into a useful format.Besides,the BROFDL-AASC model includes Discriminative Fuzzy-based Restricted Boltzmann Machine(DFRBM)model for the identification and categorization of sentiments.Furthermore,the BRO algorithm is exploited for optimal fine-tuning of the hyperparameters related to the FBRBM model.This scenario establishes the novelty of current study.The performance of the proposed BROFDL-AASC model was validated and the outcomes demonstrate the supremacy of BROFDL-AASC model over other existing models.

Shanghai Ballet's Classie Version of Swan Lake Wentto the Netherlands

Invited by the China Arts and Entertainment Group Ltd,Shanghai Ballet has performed the classic version of Swan Lake at the 136-year-old Royal Theatre Carre in Amsterdam on August 31 to start the fourth European tour since 2015.

NEWS & EVENT

1AUDEMARS PIGUET爱彼纷呈新品古今交融2月24日,AUDEMARS PIGUET爱彼重磅发布2023全新时计,其中,Royal Oak Offshore皇家橡树离岸型系列今年将迎来30年诞辰,多款新品一如既往地在材质、配色等方面进行创新演绎,展现出更阳刚和更富运动气息的风范。

外文编辑应把握翻译和编译的界限

近年来,许多报刊杂志、电台和电视台纷纷发表各种翻译和编译文体的作品,从学术专著到科幻小说,从科技资料到珍闻趣事,……体裁新颖,内容丰富,吸引越来越多读者的青睐。 那么,何谓翻译?何谓编译?两者之间又有何区别?这是每位编辑,特别是外文编辑,需要认真分清的两个基本概念。在审阅、定稿时,外文编辑更需要严格把握两者之间的界限,切不可把翻译作品和编译作品混为一谈。

美洲、加拿大塑料模板的发展与应用

美洲、加拿大塑料模板与欧洲塑料模板不同,其开发的塑料模板主要为塑料装饰衬模、全塑料装饰模板和泡沫保温塑料模板等。以加拿大泡沫保温塑料模板为例,这种模板施工操作轻便,不需大型施工机械,模板一次性使用不用拆除,墙体还有良好的保温效果和隔音效果。特别是ROYAL建筑模板既可作墙体模板,又可以作为墙体的一部分,在混凝土浇灌完后,不用拆除模板,也不用进行墙面装修,所以施工速度非常快,并且质量很高。

混沌控制与混沌同步理论的发展

2004年7月19～20日，本人参加了在澳大利亚墨尔本市皇家墨尔本技术研究所（the Royal Melbourne Institute of Technology）举办的“第3届混沌控制和同步亚太研讨会”

英国剧场设计与运营——访英随感

2014年6月7日～14日,笔者至伦敦参加由英国剧场技术协会主办的2014年国际剧场工程及建筑会议（ITEAC2014）。其间,笔者受邀作了一场关于中国现代剧场的舞台发展报告,并作为五位主要嘉宾之一参加了＂未来剧场的20个想法＂的讨论会;会后,重点访问英国皇家歌剧院（Royal Opera House）、皇家节日音乐厅（Royal Festival Hall）、阿德菲剧场（Adelphi Theatre）和天普剧场（Temple Studio）等4个剧场。这几个剧场的规模、类型、舞台形式及配置都有很大的差异,体现出英国剧场的多样性，和其作为世界表演艺术中心的价值。

英国皇家建筑师学会评估视察委员会的构成和工作程序

导言1.“皇家学会的目标是建筑学的进步并促进与此相关的文理知识的发展”,“皇家学会可以授予文凭、证书或其它形式的认可”。(见皇家学会建立三年后的1837年所批准的第一个皇家宪章的条款2.2。)2.为了实现这些目标和权利,英国皇家建筑师学会(RIBA)设立了其自己的建筑学考试,1882年这种考试具有强制性。后来,根据学院的要求,又着手进行对学院开设课程和考试的认可,以便达到免于参加RIBA考试所要达到的必需的最低标准。1924年建立了评估视察委员会,以便派去评估视察小组到学院进行现场调查。

正例举隅

M.L.McGlashan教授在他编写的《物理化学量和单位》一书中,曾把计量单位比作物理化学学科的“语法”。根据这些准则来演算问题、书写实验报告以及撰写科学论文,彼此就有了一种易于理解的“语言”。在教材的编撰中往往要涉及到许多量,怎样进行正确而清晰的描写,这里就有一个使用法定计量单位的问题。本文根据综合大学化学系《物理化学教学大纲》范围,选辑一些用法定计量单位演算的典型例题,供参考。

聚焦蜂王浆主蛋白功能研究

由同一只蜂王产下的受精卵发育成的幼虫若在整个幼虫期都喂蜂王浆,幼虫只需13天就发育成性器官完全的蜂王;若在前三天喂蜂王浆,之后喂蜂粮(蜂蜜和花粉的混合物),幼虫18天后才发育成性器官不完全的工蜂。蜂王在繁殖高峰期,每天的产卵数达到2000粒,超过自身的体重。蜂王浆的寿命一般是2~3年,而工蜂寿命只有30~40天。蜂王浆神奇的功效引起了许多科学家极大的兴趣。蜂王浆(Royal Jelly,RJ)是哺育蜂咽下腺与上颚腺分泌的供3日龄以内蜜蜂幼虫和蜂王食用的浆状物质。蜂王浆中一般含水量为64.5~68.5%,蛋白质12~14%。

浮式生产系统波浪中运动响应的国际性计算互比

1989年初,挪威皇家科学与工业研究院(The Royal Norwegian Council for Scientific andIndustrial Research,简写为NTNF)提出了一项关于海上石油与天然气浮式生产系统的研究计划FPS—2000,为期三年,总经费七千万挪威克朗(约合一千万美元),经费的一半由NTNF自身负担,另一半由各大石油公司提供,整个研究计划有极为强烈的经济效益方面的考虑。NTNF提出该计划的主要目标是:“在可以接受的安全标准所允许的范围内,降低在挪威大陆架上油气开采的成本,帮助海事工业领域内的挪威公司在世界市场上竞争”。

Role of microglial cells in photoreceptor degeneration

Inherited photoreceptor degeneration in humans constitutes a major cause of irreversible blindness in the world.They comprise various diseases,but retinitis pigmentosa is the most frequently observed.Retinitis pigmentosa is commonly limited to the eye,where there is progressive photoreceptor degeneration,rods and secondarily cones.The mechanisms of cone and rod degeneration continue to be investigated,since most of the mutations causing retinitis pigmentosa affect rods and thus,the secondary death of cones is an intriguing question but,ultimately,the cause of blindness.Understanding the mechanisms of rod and cone degeneration could help us to develop therapies to stop or,at least,slow down the degeneration process.Secondary cone degeneration has been attributed to the trophic dependence between rods and cones,but microglial cell activation could also have a role.In this review,based on previous work carried out in our laboratory in early stages of photoreceptor degeneration in two animal models of retinitis pigmentosa,we show that microglial cell activation is observed prior to the the initiation of photoreceptor death.We also show that there is an increase of the retinal microglial cell densities and invasion of the outer retinal layers by microglial cells.The inhibition of the microglial cells improves photoreceptor survival and morphology,documenting a role for microglial cells in photoreceptor degeneration.Furthermore,these results indicate that the modulation of microglial cell reactivity can be used to prevent or diminish photoreceptor death in inherited photoreceptor degenerations.

重返“节日之城” 爱丁堡边缘艺术节生态之思考

重返故地 2012年,我带着导演作品《我是月亮》来到爱丁堡边缘艺术节演出,经历至今难忘。当剧组一行拖着塞满服装道具的行李箱,带着二十几个小时的国际旅行的疲惫挪进爱丁堡的古城区,我们瞬间被爱丁堡的热烈所点燃。＂戏剧的海洋!＂俗套的形容词在我的脑海里不断地重复着,但我当时想不出任何其他更贴切的语汇。铺天盖地的演出海报一片片一层层地张贴在海报栏、建筑墙体、电线杆、垃圾桶、围墙、栏杆和你能想象到的任何可以张贴的平面：酒吧、咖啡厅、书报亭和快餐店的老板也不会拒绝你在店里放置宣传单。

Differential volatile organic compounds in royal jelly associated with different nectar plants

The aim of this work was to distinguish volatile organic compound（VOC） profiles of royal jelly（RJ） from different nectar plants. Headspace solid-phase microextraction（HS-SPME） was used to extract VOCs from raw RJ harvested from 10 nectar plants in flowering seasons. Qualitative and semi-quantitative analysis of VOCs extracts were performed by gas chromatography-mass spectrometry（GC-MS）. Results showed that VOC profiles of RJ from the samples were rich in acid, ester and aldehyde compound classes, however, contents of them were differential, exemplified by the data from acetic acid, benzoic acid methyl ester, hexanoic acid and octanoic acid. As a conclusion, these four VOCs can be used for distinguishing RJ harvested in the seasons of different nectar plants.

Major royal jelly proteins accelerate onset of puberty and promote ovarian follicular development in immature female mice

The major royal jelly proteins(MRJPs)are the central constituents responsible for the specific activities of royal jelly.Here MRJPs via oral administration daily for 45 consecutive days were evaluated the effects on the reproductive parameters in immature female mice(FM).Neonatal FM were divided into four groups fed MRJPs with doses of 0,125,250 and 500 mg/kg/body weight(M125,M250 and M500).The results in M125,M250 and M500 showed that the times of estrus were accelerated by 10.7%,15.5%and 10.7%,the secondary follicles number were increased by 50.7%,78.8%and 38.6%,the Graafian follicles were increased by 600.0%and 774.0%and 150.0%,respectively.M500 induced multi-oocyte follicles.The serum estradiol levels of the three groups were increased by 47.1%,64.9%and 31.1%,the action of MRJPs raising hormone secretion level is mainly via upregulating expression of ERˇgene.Antioxidant parameters of ovarian tissue showed that the malondialdehyde levels in M125 and M250 were decreased,the superoxide dismutase activities and glutathione peroxidase activities in M125 and M250 were increased.In conclusion,MRJPs may accelerate onset of puberty and promote follicular development in FM.Our findings would facilitate better understanding of the benefit effect of MRJPs as the key ingredient in royal jelly on promoting fertility performance.

Ex vivo antioxidant effects of D-004, a lipid extract from Roystonea regia fruits, on rat prostate tissue

Aim： To investigate whether oral treatment with D-004, a lipid extract of the Cuban royal palm fruit, produces antioxidant effects in the prostate tissue of normal and testosterone （T）-treated rats. Methods： In our first experiment, normal rats were distributed into five groups： one group treated with the vehicle and four groups treated with D-004 （100, 200, 400 or 800 mg/kg）. In our second experiment, rats were randomized into five groups： a negative control group and four T-injected groups. The latter were comprised of a positive control group treated with the vehicle, and three groups treated with D-004 （200, 400 or 800 mg/kg）. Results： In normal rats, D-004 （100-800 mg/kg） inhibited significantly and dose-dependently iron-initiated malondialdehyde （MDA） accumulation in prostate homogenates （35.7%-80.0%） vs. the controls. D-004 （200-800 mg/kg） significantly reduced baseline MDA and carbonyl groups in prostate homogenates of normal rats to approximately 80% and 50%, respectively, and totally （100%） in T-treated rats. Conclusion： Oral treatment with D-004 reduced MDA and carbonyl groups dose-dependently and markedly in normal and T-injected rats. These findings show that D-004 given at doses effective to prevent prostate hyperplasia also produces antioxidant effects in the prostate tissue.