A new ruthenium complex containing bidentate xanthate ligands was synthesized in a good yield. This complex was characterized by elemental analysis, proton nuclear magnetic resonance（tH NMR）, Fourier transform infra...A new ruthenium complex containing bidentate xanthate ligands was synthesized in a good yield. This complex was characterized by elemental analysis, proton nuclear magnetic resonance（tH NMR）, Fourier transform infrared（FTIR） and UV-Vis spectroscopies. The cyclic voltammetry of the complex revealed one quasi-redox wave centered at Ru（III）/Ru（II） couple, indicating its catalytic potential. So the preparation of a glass carbon electrode modified with ruthenium xanthate complex and its electrocatalytic activity toward the oxidation of tryptophan（Trp） were also studied. The experimental results show that the modified electrode had excellent electrocatalytic activity for the oxidation of tryptophan. Moreover, under the optimized conditions, the oxidation peak current was propor- tional to tryptophan concentration in a range of 2.5×10-7 to 5.0× 10-5 mol/L with a correlation coefficient of 0.9928 and a detection limit of 8.3 × 10-8 mol/L（S/N=3）. Using the proposed method, tryptophan was successfully determined in pharmaceutical samples with standard addition method.展开更多
基金Supported by the National Natural Science Foundation of China（Nos.21071005, 50975002） and the Natural Science Foundation of the Education Bureau of Anhui Province, China（No.K J2011A054）.
文摘A new ruthenium complex containing bidentate xanthate ligands was synthesized in a good yield. This complex was characterized by elemental analysis, proton nuclear magnetic resonance（tH NMR）, Fourier transform infrared（FTIR） and UV-Vis spectroscopies. The cyclic voltammetry of the complex revealed one quasi-redox wave centered at Ru（III）/Ru（II） couple, indicating its catalytic potential. So the preparation of a glass carbon electrode modified with ruthenium xanthate complex and its electrocatalytic activity toward the oxidation of tryptophan（Trp） were also studied. The experimental results show that the modified electrode had excellent electrocatalytic activity for the oxidation of tryptophan. Moreover, under the optimized conditions, the oxidation peak current was propor- tional to tryptophan concentration in a range of 2.5×10-7 to 5.0× 10-5 mol/L with a correlation coefficient of 0.9928 and a detection limit of 8.3 × 10-8 mol/L（S/N=3）. Using the proposed method, tryptophan was successfully determined in pharmaceutical samples with standard addition method.
