Imidazo[1,2-a]pyridines have been successfully synthesized in moderate to good yields via a tandem three- component reaction of ethyl 2-（3-oxo-3-arylpropanethioamido）acetates with aromatic aldehydes and malononitril...Imidazo[1,2-a]pyridines have been successfully synthesized in moderate to good yields via a tandem three- component reaction of ethyl 2-（3-oxo-3-arylpropanethioamido）acetates with aromatic aldehydes and malononitrile by means of microwave irradiation using DABCO as the catalyst. The advantages of this method including high chemo- and regioselectivity make this new strategy highly attractive.展开更多
文摘Imidazo[1,2-a]pyridines have been successfully synthesized in moderate to good yields via a tandem three- component reaction of ethyl 2-（3-oxo-3-arylpropanethioamido）acetates with aromatic aldehydes and malononitrile by means of microwave irradiation using DABCO as the catalyst. The advantages of this method including high chemo- and regioselectivity make this new strategy highly attractive.
