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新高速双极外向流源S39和IRAS 06306+0232
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作者 秦胜利 吴月芳 《中国科学(A辑)》 CSCD 北大核心 2002年第4期374-379,共6页
用紫金山天文台13.7m毫米波望远镜对水脉泽源S39和IRAS 06306+0232两个大质量星形成区进行了12CO J=1-0的成图观测,发现这两个源都有双极外向流.计算了它们的参量.结果表明:外向流质量和星体质量流失率比低质量年轻星体附近的外向流要... 用紫金山天文台13.7m毫米波望远镜对水脉泽源S39和IRAS 06306+0232两个大质量星形成区进行了12CO J=1-0的成图观测,发现这两个源都有双极外向流.计算了它们的参量.结果表明:外向流质量和星体质量流失率比低质量年轻星体附近的外向流要大得多.它们的成协红外源的热光度也大,但外向流与其成协源关系的分析表明,辐射压仍不足以驱动外向流.S39中有多个不同演化状态的星体存在,说明这个区域中的恒星形成可能是一个序列,而不是爆发形成. 展开更多
关键词 量阶介质动力学 喷流 恒星形成 质量流失率 星体演化 高速双极外向流源 s39 IRAS06306+0232
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中籼型温光敏核不育系丰39S的选育 被引量:5
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作者 周桂香 张国良 徐继萍 《安徽农业科学》 CAS 北大核心 2007年第35期11432-11433,共2页
[目的]研究丰39S的选育过程。[方法]丰39S是利用广占63S经离子束诱变处理,经自然压力法选育而成的温光敏核不育系。于2003~2005年研究了丰39S的形态特征、育性表现及其配制组合的表现。[结果]该不育系株型紧凑,分蘖力强,抗性强,米质优... [目的]研究丰39S的选育过程。[方法]丰39S是利用广占63S经离子束诱变处理,经自然压力法选育而成的温光敏核不育系。于2003~2005年研究了丰39S的形态特征、育性表现及其配制组合的表现。[结果]该不育系株型紧凑,分蘖力强,抗性强,米质优,不育起点温度较低,不育性稳定。2003、2004年镜检期花粉败育率100%。2005年大田鉴定典败花粉8.43%,余为无花粉败育,自交不结实率为99.90%。2004年三亚地区结实率49.10%,实产3307.5kg/hm2。所配组合丰两优4号高产、抗病,结实率81.60%,千粒重27.7g。2005年区域试验平均单产8.59t/hm2,比汕优63增产8.99%,达极显著水平。[结论]丰39S的育性符合光温敏核不育系选育指标要求,配组后代株型紧凑,生长势强,丰产性好。 展开更多
关键词 籼稻 温光敏核不育系 丰39S 选育
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野生型DJ-1与A39S突变型DJ-1表达的单克隆细胞株基因表达谱分析(英文) 被引量:1
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作者 刘振华 唐北沙 +4 位作者 何丹 王磊 肖智权 严新翔 郭纪锋 《中南大学学报(医学版)》 CAS CSCD 北大核心 2014年第4期325-332,共8页
目的:探讨DJ-1基因A39S突变在帕金森病发病过程中的作用机制,以及其是否可能通过转录调控活性导致相关基因表达异常。方法:建立能够稳定表达空载体和野生型DJ-1蛋白,以及A39S突变型DJ-1蛋白的HEK293单克隆细胞株。利用基因芯片技术对不... 目的:探讨DJ-1基因A39S突变在帕金森病发病过程中的作用机制,以及其是否可能通过转录调控活性导致相关基因表达异常。方法:建立能够稳定表达空载体和野生型DJ-1蛋白,以及A39S突变型DJ-1蛋白的HEK293单克隆细胞株。利用基因芯片技术对不同组别细胞株进行差异性表达基因筛选。结果:与空载体组比较,野生型DJ-1组有14个基因表达上调,28个基因表达下调;A39S突变型DJ-1组有6个基因表达上调;2个基因表达下调;A39S突变型DJ-1组与野生型型DJ-1组比较发现只有1个基因表达下调。具有表达差异性的基因分别参与信号转导、基因转录调控、细胞周期、细胞凋亡、氧化应激等生物学过程。结论:A39S突变型DJ-1蛋白可能通过直接或间接方式对这些差异基因进行表达调控影响这些通路的正常功能,而参与帕金森病的发病。 展开更多
关键词 DJ-1 A39S突变 基因表达谱 DNA基因芯片 UGT2B7基因
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水稻两用核不育系丰39S的选育与利用 被引量:1
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作者 周红英 蒋继武 +1 位作者 汪华春 徐晓莉 《安徽农业科学》 CAS 2012年第25期12412-12413,12451,共3页
[目的]研究丰39S的选育过程、配组表现及其在生产上的利用。[方法]以广占63S为材料,采用离子束诱变处理,经5年7代选育而成的两用核不育系,研究其形态特征、育性转换规律、配制组合的表现及制种繁殖技术要点。[结果]丰39S具有不育起点温... [目的]研究丰39S的选育过程、配组表现及其在生产上的利用。[方法]以广占63S为材料,采用离子束诱变处理,经5年7代选育而成的两用核不育系,研究其形态特征、育性转换规律、配制组合的表现及制种繁殖技术要点。[结果]丰39S具有不育起点温度低、农艺性状优良、米质较优、广亲和、高异交结实率、配合力强等优点,2006年通过安徽省农作物品种审定委员会审定。利用丰39S已选配出一系列高产优质杂交稻组合通过国家或审级审定。[结论]丰39S是一个综合性状优良的水稻两用核不育系,配组表现好,具有较大的应用前景。 展开更多
关键词 两用核不育系 丰39S 选育与利用
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突变及SUMO化修饰对DJ-1线粒体定位的影响
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作者 李丽芝 周晓兰 +1 位作者 唐北沙 郭纪锋 《中风与神经疾病杂志》 CAS 2021年第9期773-776,共4页
目的探究帕金森病(Parkinson’s disease,PD)致病基因DJ-1致病突变A39S以及DJ-1的SUMO化修饰对DJ-1蛋白在线粒体亚细胞定位的影响。方法构建可稳定表达野生型、A39S突变型、K130R突变型及A39S-K130R双突变型DJ-1蛋白及SUMO-1蛋白的COS-... 目的探究帕金森病(Parkinson’s disease,PD)致病基因DJ-1致病突变A39S以及DJ-1的SUMO化修饰对DJ-1蛋白在线粒体亚细胞定位的影响。方法构建可稳定表达野生型、A39S突变型、K130R突变型及A39S-K130R双突变型DJ-1蛋白及SUMO-1蛋白的COS-7细胞系。再通过Western印记、激光共聚焦及免疫荧光技术观察DJ-1蛋白表达情况及亚细胞定位,免疫荧光共定位观察DJ-1和SUMO-1是否存在相互作用。结果免疫荧光表明DJ-1蛋白主要分布在细胞浆中,也存在于细胞核中,野生型和K103R型DJ-1蛋白部分分布在线粒体上,A39S及A39S-K130R突变型DJ-1蛋白大部分转移至线粒体上,SUMO-1主要分布于细胞核及核周,呈斑点状分布。免疫荧光共定位发现四种DJ-1蛋白均与SUMO-1蛋白存在共定位。结论DJ-1致病突变A39S使DJ-1蛋白从胞浆转移至线粒体上;DJ-1与SUMO-1存在共定位,两者可能存在相互作用。 展开更多
关键词 帕金森病 DJ-1 SUMO-1 A39S 线粒体
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A novel image encryption scheme based on Keplers third law and random Hadamard transform 被引量:3
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作者 罗玉玲 周戎龙 +2 位作者 刘俊秀 丘森辉 曹弋 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第12期146-159,共14页
In this paper, a novel image encryption scheme based on Keplers third law and random Hadamard transform is proposed to ensure the security of a digital image. First, a set of Kepler periodic sequences is generated to ... In this paper, a novel image encryption scheme based on Keplers third law and random Hadamard transform is proposed to ensure the security of a digital image. First, a set of Kepler periodic sequences is generated to permutate image data, which is characteristic of the plain-image and the Keplers third law. Then, a random Hadamard matrix is constructed by combining the standard Hadamard matrix with the hyper-Chen chaotic system, which is used to further scramble the image coefficients when the image is transformed through random Hadamard transform. In the end, the permuted image presents interweaving diffusion based on two special matrices, which are constructed by Kepler periodic sequence and chaos system. The experimental results and performance analysis show that the proposed encrypted scheme is highly sensitive to the plain-image and external keys, and has a high security and speed, which are very suitable for secure real-time communication of image data. 展开更多
关键词 Kepler&#39s third law random Hadamard transform interweaving diffusion security
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Health-related quality of life in Parkinson's disease patients in northeastern Sicily, Italy An ecological perspective 被引量:1
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作者 Letteria Spadaro Lilla Bonanno +2 位作者 Giuseppe Di Lorenzo Placido Bramanti Silvia Marino 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第17期1615-1622,共8页
Parkinson's disease has a negative impact on health-related quality of life in Parkinson's disease patients. Depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopam... Parkinson's disease has a negative impact on health-related quality of life in Parkinson's disease patients. Depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopaminergic drugs are the variables that most affect health-related quality of life. The ecological model of human development focuses attention on both individual and social environmental factors as targets for health interventions. From this perspective, the aim of this cross-sectional survey was to evaluate the influence of gender, family size and perceived autonomy on health-related quality of life in Parkinson's disease patients in nOrtheastern Sicily, Italy. Ninety Parkinson's disease patients, attending the Movement Disorders Clinic at IRCCS Centro Neurolesi "Bonino-Pulejo" (Messina), were consecutively enrolled. The Unified Parkinson Disease Rating Scale motor subscale (UPDRS-Ⅲ) scores, the Parkinson Disease Questionnaire-39 Item scores (as a disease-specific measure of health-related quality of life), scores on the Short Form (36) Health Survey Questionnaire (as a generic measure), and answers to a brief checklist were recorded. A total of 85 Parkinson's disease patients (49% males and 51% females; mean age 70.8 ± 8.6 years mean UPDRS-Ⅲ 24.15 ± 6.55; mean disease duration 5.52 ± 4.65 years) completed the booklet of questionnaires. In the multivariate regression analysis, we included clinical and social variables as independent predictors of health-related quality of life. Our results suggest a potential compounding effect of ecological intrapersonal and interpersonal levels on health-related quality of life outcomes. Gender, self-evaluated autonomy and family size significantly impacted health-related quality of life. If quality of life is used as an indicator of treatment outcomes, an ecological perspective of the case history will be important to disclose relevant prognostic information and trigger personalized health care interventions. 展开更多
关键词 neural regeneration neurodegenerative disease health-related quality of life Parkinson's disease ecological model Parkinson's Disease Questionnaire-39 Items social variables the UnifiedParkinson Disease Rating Scale motor subscales CAREGIVER grants-supported paper
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Improvement of the thermoelectric efficiency of pyrene-based molecular junction with doping engineering
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作者 Mohammad Farid Jamali Meysam Bagheri Tagani Hamid Rahimpour Soleimani 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第12期201-209,共9页
In this study, the thermoelectric properties of pyrene molecule doped with boron and nitrogen atom at different sites of molecule are investigated using density functional theory and none-equilibrium Greens function f... In this study, the thermoelectric properties of pyrene molecule doped with boron and nitrogen atom at different sites of molecule are investigated using density functional theory and none-equilibrium Greens function formalism in the linear response regime. Our calculations show that when the impurities are added to the edge of the molecule, the anti-resonant peaks will appear in the transmission diagram in the vicinity of the Fermi energy level. So it increases the thermoelectric figure of merit of the system in comparison with the one that the impurity is located in the center of molecule. Additionally, the seebeck coefficient signs are not the same among the B, N, and N & B doped devices, indicating that the types of the carriers can be changed with different types of doping. 展开更多
关键词 THERMOPOWER PYRENE density functional theory none-equilibrium Green&#39s function method DOPING
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Effect of Abnormal Posture on Quality of Life in Patients with Parkinson’s Disease 被引量:1
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作者 Kyohei Mikami Makoto Shiraishi Tsutomu Kamo 《Advances in Parkinson's Disease》 2016年第2期7-14,共8页
Background: Relationship between abnormal posture and QOL of Parkinson's disease is not clear. Objectives: To clarify the association between quality of life (QOL) and abnormal posture in patients with Parkinson’... Background: Relationship between abnormal posture and QOL of Parkinson's disease is not clear. Objectives: To clarify the association between quality of life (QOL) and abnormal posture in patients with Parkinson’s disease (PD) and examine which QOL dimensions are involved. Methods: This study retrospectively examined PD patients (n = 57) who had undergone outpatient rehabilitation between January and March 2014. Evaluation items were Modified Hoehn Yahr (H-Y) stage, Unified Parkinson’s Disease Rating Scale (UPDRS)-Part III score, Timed Up and Go test (TUG, 3-m walking) result, Parkinson’s Disease Questionnaire (PDQ)-39 score, and the angle of forward and lateral trunk flexion in the standing position. Statistical analysis was performed to reveal the relationship between the total PDQ-39 score and individual evaluation items and which QOL dimensions were affected by abnormal posture due to forward or lateral flexion. Results: A total of 38 PD patients (17 men, 21 women;mean age, 73.2 ± 8.6 years) were enrolled. Among the evaluation items, lateral flexion angle showed a significant correlation with the total PDQ-39 score (r = 0.422, P = 0.008). PDQ-39 dimensions showing an association with forward flexion were activities of daily living (ADL) (P = 0.002) and communication (P = 0.007), whereas ADL (P = 0.004), communication (P = 0.021), and social support (P = 0.029) were associated with lateral flexion. Mobility was not associated with forward or lateral flexion. Conclusion: The present findings revealed a correlation between lateral flexion and QOL in PD patients. Among the PDQ-39 dimensions, ADL and communication were associated with abnormal posture. 展开更多
关键词 Parkinson’s Disease Abnormal Postural Quality of Life Parkinson’s Disease Questionnaire (PDQ)-39
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水稻光温敏核不育系丰39S异交特性研究 被引量:1
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作者 徐晓莉 汪华春 +2 位作者 夏泽静 周红英 吴晓亮 《杂交水稻》 CSCD 北大核心 2016年第4期21-25,共5页
丰39S开花与抽穗历期长,见花期、盛花期分别较见穗期、盛穗期迟1 d,开花盛期与抽穗盛期天数相同;花时较集中,有明显的开花高峰,午前花所占比例较大,开颖历期长,开颖角度较大,柱头体积较大,柱头外露率高,但颖花不闭颖率高,柱头活力也较培... 丰39S开花与抽穗历期长,见花期、盛花期分别较见穗期、盛穗期迟1 d,开花盛期与抽穗盛期天数相同;花时较集中,有明显的开花高峰,午前花所占比例较大,开颖历期长,开颖角度较大,柱头体积较大,柱头外露率高,但颖花不闭颖率高,柱头活力也较培矮64S低;对"九二○"敏感,在抽穗10%~20%时喷施"九二○"300~375 g/hm^2可取得良好的解除包颈的效果;与不同类型父本制种的异交结实率有差异。根据丰39S异交结实特性,提出了相应的高产制种关键技术措施。 展开更多
关键词 杂交水稻 光温敏核不育系 丰39S 异交特性
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华为3com“IRF”智能弹性架构Quidway以太网交换机
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作者 王炳晨 《微电脑世界》 2005年第1期42-42,共1页
2004年12月16日.华为3Com发布了其“IRF”智能弹性架构技术和Quidway S39/56/65系列以太网交换机。
关键词 华为3com公司 “IRF”智能弹性架构 QUIDWAY s39系列 以太网交换机 性能 规格
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优质粳稻光温敏核不育系L39S的选育 被引量:1
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作者 周圆圆 马科 +2 位作者 华泽田 李志彬 王丕武 《杂交水稻》 CSCD 北大核心 2014年第3期20-22,共3页
L39S是以高柱头外露率的粳稻光温敏核不育系DS为母本,以含稻瘟病抗性基因Pib的优质粳稻品系L39为父本杂交选育而成的粳稻光温敏核不育系,表现育性稳定,株叶形态好,米质优、抗性较强、配合力高等特点,2011年9月通过天津市种子管理站现场... L39S是以高柱头外露率的粳稻光温敏核不育系DS为母本,以含稻瘟病抗性基因Pib的优质粳稻品系L39为父本杂交选育而成的粳稻光温敏核不育系,表现育性稳定,株叶形态好,米质优、抗性较强、配合力高等特点,2011年9月通过天津市种子管理站现场鉴定。 展开更多
关键词 粳稻 光温敏核不育系 L39S 优质 选育
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Validity and reliability testing of the Chinese (mainland) version of the 39-item Parkinson's Disease Questionnaire (PDQ-39) 被引量:26
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作者 Wei LUO Xiao-hong GUI Bo WANG Wen-ying ZHANG Zhi-yuan OUYANG Yi GUO Bao-rong ZHANG Mei-ping DING 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2010年第7期531-538,共8页
The 39-item Parkinson's Disease Questionnaire (PDQ-39) has been tested in many languages, but not in Chinese mainland. We aimed to assess the Chinese (mainland) version of the PDQ-39. Seventy-one subjects with Par... The 39-item Parkinson's Disease Questionnaire (PDQ-39) has been tested in many languages, but not in Chinese mainland. We aimed to assess the Chinese (mainland) version of the PDQ-39. Seventy-one subjects with Parkinson's disease (PD) completed the PDQ-39 and the Medical Outcomes Study 36-item Short Form Health Survey (SF-36). All subjects were retested with the PDQ-39 a week later. The united Parkinson's disease rating scale (UPDRS) and the Hoehn and Yahr (H & Y) scale were also used to evaluate the subjects. Reliability was assessed by Cron- bach's α and intra-class correlation coefficient (ICC). Validity was examined in terms of agreement with SF-36, UPDRS, and H & Y scales. The Chinese (mainland) version of the PDQ-39 demonstrated acceptable reliability (Cronbach's α: 0.84-0.88; ICC: 0.56-0.82). The item-total correlations (0.33-0.88) and scaling success rates (77.56%) indicated satisfactory convergent and discriminant validity of the PDQ-39 items. The correlations between related constructs of the PDQ-39 and UPDRS (r=0.44-0.68) and between those of the PDQ-39 and SF-36 (r=(-0.46)-(-0.69)) were all statistically significant (P<0.01). Except for stigma, cognitions, and bodily discomfort, all other dimensions of the PDQ-39 significantly discriminated patients at different H & Y stages indicated by the H & Y scale. Although our observations indicate that some problematic subscales of this version of the PDQ-39 could be improved upon, this study suggests acceptable reliability and validity of the Chinese (mainland) version of the PDQ-39. 展开更多
关键词 39-item Parkinson’s Disease Questionnaire (PDQ-39) Quality of life Validity RELIABILITY
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