AIMTo determine peripapillary retinal fiber layer thickness (RNFL) measured with spectral domain optical coherence tomography (SD-OCT) in normal and glaucomatous eyes in a large sample of exclusively white population ...AIMTo determine peripapillary retinal fiber layer thickness (RNFL) measured with spectral domain optical coherence tomography (SD-OCT) in normal and glaucomatous eyes in a large sample of exclusively white population and compare results with other similarly constructed studies.展开更多
Purpose: We compared the thickness of circumpapillary retinal nerve fiver layer (cpRNFL) and macular ganglion cell layer with inner plexiform layer (GCL + IPL) using Cirrus HD-OCT (Ver.6.0: Carl Zeiss). Materials and ...Purpose: We compared the thickness of circumpapillary retinal nerve fiver layer (cpRNFL) and macular ganglion cell layer with inner plexiform layer (GCL + IPL) using Cirrus HD-OCT (Ver.6.0: Carl Zeiss). Materials and Methods: This study included 12 eyes of normal controls, 10 eyes of preperimetric glaucoma (PPG) with loss of RNFL either in superior or in inferior hemisphere without visual field defects, and 22 eyes of glaucoma eyes with visual field defects restricted to upper hemifield (UHFD: early 10 eyes, severe 12 eyes). The cpRNFL thickness analyzed from disk center by dividing into 12 sectors. The GCL + IPL thickness analyzed from central fovea by dividing into six sectors. Both compared between normal eye group and other 3 groups using the average value of each sectors. Result: The cpRNFL and the GCL + IPL thickness were obviously thin as compared with normal eyes. Conclusion: Even if it is in the state where abnormalities are not detected using the Humphrey field Analyzer, it is suggested that the early structural change of glaucoma has already arisen.展开更多
目的：分析研究视网膜黄斑区神经节复合体（ GCC）的厚度与眼轴长度的相关关系，以期指导临床应用。方法前瞻性病例分析研究。选取2014年5月至2014年10月期间在山东省眼科医院屈光中心就诊的患者连续性病例共93例（184只眼）。根据眼轴...目的：分析研究视网膜黄斑区神经节复合体（ GCC）的厚度与眼轴长度的相关关系，以期指导临床应用。方法前瞻性病例分析研究。选取2014年5月至2014年10月期间在山东省眼科医院屈光中心就诊的患者连续性病例共93例（184只眼）。根据眼轴长度分为A组（眼轴22～24 mm），15例（29只眼）；B组（眼轴＞24～26 mm），50例（100只眼）；C组（眼轴＞26 mm），28例（55只眼）。眼部检查指标包括：眼轴长度、平均GCC厚度（ Avg．GCC）、上方GCC厚度（ Sup．GCC）、下方GCC厚度（ Ing．GCC）、局部丢失容积（ FLV）及总体丢失容积（ GLV）。分析3组间GCC厚度的差异及眼轴长度与GCC厚度的相关关系。对数据进行单因素方差分析和Pear-son相关性分析。结果3组受试者眼轴长度分别为A组（23．31±0．53） mm，B组（25．20±0．49） mm，C组（26．91±0．99）mm；A组、B组、C组Avg．GCC分别为（97．19±5．09）μm、（92．74±5．50）μm、（92．84±5．74）μm，3组比较差异有统计学意义（ P ＝0．001）；3组Sup．GCC与Ing．GCC 分别为（97．56±5．06）μm、（93．37±6．18）μm、（93．22±5．99）μm （ P ＝0．002）和（96．83±5．51）μm、（92．11±5．80）μm、（92．47±5．96）μm （ P ＝0．001），3组间比较二者差异均有统计学意义；GLV分别为（5．56±4．19）％、（8．28±5．46）％、（8．61±5．13）％，3组间比较差异有统计学意义（ P ＝0．026）。此外，3组间FLV（％）比较无统计学意义（ F ＝0．659， P ＝0．518）。 Pearson分析结果显示：GCC厚度值参数与眼轴长度呈显著负相关（ P ＜0．05）。结论 GCC厚度与眼轴长度呈负相关，随着眼轴变长，GCC厚度逐渐变薄。展开更多
文摘AIMTo determine peripapillary retinal fiber layer thickness (RNFL) measured with spectral domain optical coherence tomography (SD-OCT) in normal and glaucomatous eyes in a large sample of exclusively white population and compare results with other similarly constructed studies.
文摘Purpose: We compared the thickness of circumpapillary retinal nerve fiver layer (cpRNFL) and macular ganglion cell layer with inner plexiform layer (GCL + IPL) using Cirrus HD-OCT (Ver.6.0: Carl Zeiss). Materials and Methods: This study included 12 eyes of normal controls, 10 eyes of preperimetric glaucoma (PPG) with loss of RNFL either in superior or in inferior hemisphere without visual field defects, and 22 eyes of glaucoma eyes with visual field defects restricted to upper hemifield (UHFD: early 10 eyes, severe 12 eyes). The cpRNFL thickness analyzed from disk center by dividing into 12 sectors. The GCL + IPL thickness analyzed from central fovea by dividing into six sectors. Both compared between normal eye group and other 3 groups using the average value of each sectors. Result: The cpRNFL and the GCL + IPL thickness were obviously thin as compared with normal eyes. Conclusion: Even if it is in the state where abnormalities are not detected using the Humphrey field Analyzer, it is suggested that the early structural change of glaucoma has already arisen.
文摘目的：分析研究视网膜黄斑区神经节复合体（ GCC）的厚度与眼轴长度的相关关系，以期指导临床应用。方法前瞻性病例分析研究。选取2014年5月至2014年10月期间在山东省眼科医院屈光中心就诊的患者连续性病例共93例（184只眼）。根据眼轴长度分为A组（眼轴22～24 mm），15例（29只眼）；B组（眼轴＞24～26 mm），50例（100只眼）；C组（眼轴＞26 mm），28例（55只眼）。眼部检查指标包括：眼轴长度、平均GCC厚度（ Avg．GCC）、上方GCC厚度（ Sup．GCC）、下方GCC厚度（ Ing．GCC）、局部丢失容积（ FLV）及总体丢失容积（ GLV）。分析3组间GCC厚度的差异及眼轴长度与GCC厚度的相关关系。对数据进行单因素方差分析和Pear-son相关性分析。结果3组受试者眼轴长度分别为A组（23．31±0．53） mm，B组（25．20±0．49） mm，C组（26．91±0．99）mm；A组、B组、C组Avg．GCC分别为（97．19±5．09）μm、（92．74±5．50）μm、（92．84±5．74）μm，3组比较差异有统计学意义（ P ＝0．001）；3组Sup．GCC与Ing．GCC 分别为（97．56±5．06）μm、（93．37±6．18）μm、（93．22±5．99）μm （ P ＝0．002）和（96．83±5．51）μm、（92．11±5．80）μm、（92．47±5．96）μm （ P ＝0．001），3组间比较二者差异均有统计学意义；GLV分别为（5．56±4．19）％、（8．28±5．46）％、（8．61±5．13）％，3组间比较差异有统计学意义（ P ＝0．026）。此外，3组间FLV（％）比较无统计学意义（ F ＝0．659， P ＝0．518）。 Pearson分析结果显示：GCC厚度值参数与眼轴长度呈显著负相关（ P ＜0．05）。结论 GCC厚度与眼轴长度呈负相关，随着眼轴变长，GCC厚度逐渐变薄。
