SDGSAT-1,the world's first science satellite dedicated to assisting the United Nations 2030 Sustainable Development Agenda,has been operational for over two and a half years.It provides valuable data to aid in imp...SDGSAT-1,the world's first science satellite dedicated to assisting the United Nations 2030 Sustainable Development Agenda,has been operational for over two and a half years.It provides valuable data to aid in implementing the Sustainable Development Goals internationally.Through its Open Science Program,the satellite has maintained consistent operations and delivered free data to scientific and technological users from 88 countries.This program has produced a wealth of scientific output,with 72 papers,including 28 on data processing methods and 44 on applications for monitoring progress toward SDGs related to sustainable cities,clean energy,life underwater,climate action,and clean water and sanitation.SDGSAT-1 is equipped with three key instruments:a multispectral imager,a thermal infrared spectrometer,and a glimmer imager,which have enabled ground-breaking research in a variety of domains such as water quality analysis,identification of industrial heat sources,assessment of environmental disaster impacts,and detection of forest fires.The precise measurements and ongoing monitoring made possible by this invaluable data significantly advance our understanding of various environmental phenomena.They are essential for making well-informed decisions on a local and global scale.Beyond its application to academic research,SDGSAT-1 promotes global cooperation and strengthens developing countries'capacity to accomplish their sustainable development goals.As the satellite continues to gather and distribute data,it plays a pivotal role in developing strategies for environmental protection,disaster management and relief,and resource allocation.These initiatives highlight the satellite's vital role in fostering international collaboration and technical innovation to advance scientific knowledge and promote a sustainable future.展开更多
目的:探究程序性细胞死亡受体蛋白-1/程序性细胞死亡配体蛋白-1(Programmed death 1/programmed death ligand1,PD-1/PD-L-1)联合微卫星稳定性检测在子宫内膜癌诊断中的应用价值。方法:将2021年1月至2024年1月我院收治的66例疑似子宫内...目的:探究程序性细胞死亡受体蛋白-1/程序性细胞死亡配体蛋白-1(Programmed death 1/programmed death ligand1,PD-1/PD-L-1)联合微卫星稳定性检测在子宫内膜癌诊断中的应用价值。方法:将2021年1月至2024年1月我院收治的66例疑似子宫内膜癌患者纳入研究。所有患者均接受刮宫病理诊断和微卫星稳定性检测及PD-1/PD-L1检测,使用Kappa检验分析微卫星稳定性检测、PD-1/PD-L1检测和联合检测与刮宫病理诊断结果的一致性,并分析诊断效能。结果:经刮宫病理诊断,66例疑似子宫内膜癌患者中共确诊51例,15例为良性病变。微卫星稳定性检测结果与病理结果的Kappa值为0.557,一致性一般;PD-1/PD-L1检测结果与病理结果的Kappa值为0.575,一致性一般;联合检测结果与病理结果的Kappa值为0.670,一致性较高。微卫星稳定性检测的敏感度、特异度和准确率分别为86.27%、73.33%、83.33%;PD-1/PD-L1检测的敏感度、特异度和准确率分别为84.31%、80.00%、83.33%;联合检测的敏感度、特异度和准确率分别为90.20%、80.00%、87.88%。结论:微卫星稳定性检测和PD-1/PD-L1检测在子宫内膜癌的临床诊断中的应用效果较好,二者联合可有效提高临床诊断率,具有较高的诊断价值。展开更多
文摘SDGSAT-1,the world's first science satellite dedicated to assisting the United Nations 2030 Sustainable Development Agenda,has been operational for over two and a half years.It provides valuable data to aid in implementing the Sustainable Development Goals internationally.Through its Open Science Program,the satellite has maintained consistent operations and delivered free data to scientific and technological users from 88 countries.This program has produced a wealth of scientific output,with 72 papers,including 28 on data processing methods and 44 on applications for monitoring progress toward SDGs related to sustainable cities,clean energy,life underwater,climate action,and clean water and sanitation.SDGSAT-1 is equipped with three key instruments:a multispectral imager,a thermal infrared spectrometer,and a glimmer imager,which have enabled ground-breaking research in a variety of domains such as water quality analysis,identification of industrial heat sources,assessment of environmental disaster impacts,and detection of forest fires.The precise measurements and ongoing monitoring made possible by this invaluable data significantly advance our understanding of various environmental phenomena.They are essential for making well-informed decisions on a local and global scale.Beyond its application to academic research,SDGSAT-1 promotes global cooperation and strengthens developing countries'capacity to accomplish their sustainable development goals.As the satellite continues to gather and distribute data,it plays a pivotal role in developing strategies for environmental protection,disaster management and relief,and resource allocation.These initiatives highlight the satellite's vital role in fostering international collaboration and technical innovation to advance scientific knowledge and promote a sustainable future.
文摘目的:探究程序性细胞死亡受体蛋白-1/程序性细胞死亡配体蛋白-1(Programmed death 1/programmed death ligand1,PD-1/PD-L-1)联合微卫星稳定性检测在子宫内膜癌诊断中的应用价值。方法:将2021年1月至2024年1月我院收治的66例疑似子宫内膜癌患者纳入研究。所有患者均接受刮宫病理诊断和微卫星稳定性检测及PD-1/PD-L1检测,使用Kappa检验分析微卫星稳定性检测、PD-1/PD-L1检测和联合检测与刮宫病理诊断结果的一致性,并分析诊断效能。结果:经刮宫病理诊断,66例疑似子宫内膜癌患者中共确诊51例,15例为良性病变。微卫星稳定性检测结果与病理结果的Kappa值为0.557,一致性一般;PD-1/PD-L1检测结果与病理结果的Kappa值为0.575,一致性一般;联合检测结果与病理结果的Kappa值为0.670,一致性较高。微卫星稳定性检测的敏感度、特异度和准确率分别为86.27%、73.33%、83.33%;PD-1/PD-L1检测的敏感度、特异度和准确率分别为84.31%、80.00%、83.33%;联合检测的敏感度、特异度和准确率分别为90.20%、80.00%、87.88%。结论:微卫星稳定性检测和PD-1/PD-L1检测在子宫内膜癌的临床诊断中的应用效果较好,二者联合可有效提高临床诊断率,具有较高的诊断价值。
