The problems of movement apparatus in children, youth and even adolescents aren’t connected with “a weakness of muscles” but with a shortening of muscles, tendons, and capsules which in orthopaedic literature is ca...The problems of movement apparatus in children, youth and even adolescents aren’t connected with “a weakness of muscles” but with a shortening of muscles, tendons, and capsules which in orthopaedic literature is called “contracture” [1] [2] [3] [4]. The older way of thinking about the problem was based on the conviction that “weak muscles” cause and make problems;we, however, present on many examples that “restriction of movements” doing by shortening of soft tissues makes contracture and incorrect position of joints, body parts, the serious and frequent clinical problems.展开更多
[Objectives]The paper was to explore the prevention and therapeutic schedule of tobacco black shank.[Methods]Different concentrations of 25 g/L fludioxonil·37.5 g/L metalaxyl-M,10 billion/mL Bacillus amyloliquefa...[Objectives]The paper was to explore the prevention and therapeutic schedule of tobacco black shank.[Methods]Different concentrations of 25 g/L fludioxonil·37.5 g/L metalaxyl-M,10 billion/mL Bacillus amyloliquefaciens,110 g/L amino acids·24 g/L manganese zinc,120 g/L calcium·20 g/L magnesium,and 4%metalaxyl-M·64%mancozeb were employed to assess their efficacy in controlling tobacco black shank.The disease index was subsequently evaluated.[Results]25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+110 g/L amino acids·24 g/L manganese zinc(transplanting dosage)or 120 g/L calcium·20 g/L magnesium(sealing dosage)(transplanting dosage:750 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2,sealing dosage:1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2)resulted in a notable impact on the prevention of tobacco black shank.The incidence in the treated area was 10.78%,a 35.72%reduction compared to the control.The estimated yield was 99700 yuan/hm 2,a 34.91%increase compared to the control.25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+120 g/L calcium·20 g/L magnesium+4%metalaxyl-M·64%mancozeb(control dosage:1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2+1.5×103 g/hm 2,1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2+1.5×103 g/hm 2,with an interval of 7 d between applications)demonstrated a significant efficacy in controlling tobacco black shank.At 7 d following the second application,the relative preventive efficacy was observed to be 88.99%.Additionally,the estimated yield was 109900 yuan/hm 2,representing an increase of 244.51%compared to the control.[Conclusions]During the transplanting and sealing stages,25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+110 g/L amino acids·24 g/L manganese zinc(transplanting dosage)or 120 g/L calcium·20 g/L magnesium(sealing dosage)may be employed to enhance the growth of tobacco plants and mitigate the occurrence of tobacco black shank.Additionally,25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+120 g/L calcium·20 g/L magnesium+4%metalaxyl-M·64%mancozeb can be utilized for the treatment of tobacco black shank during the initial incidence stage.展开更多
目的观察5肽类似物165对老年性痴呆(Alzhei mer disease,AD)模型大鼠学习记忆能力及突触后致密区蛋白95(postsynaptic density95,PSD95)和骨架蛋白Shank1表达的影响。方法将45只大鼠随机分为正常对照组、模型组和5肽类似物165治疗组,模...目的观察5肽类似物165对老年性痴呆(Alzhei mer disease,AD)模型大鼠学习记忆能力及突触后致密区蛋白95(postsynaptic density95,PSD95)和骨架蛋白Shank1表达的影响。方法将45只大鼠随机分为正常对照组、模型组和5肽类似物165治疗组,模型组和治疗组大鼠按体重3mg/kg行双侧侧脑室链脲佐菌素(streptozotocin,STZ)注射,第3天重复注射建立AD模型,对照组以人工脑脊液代替STZ。术后21d治疗组按体重0.34mg/(kg.d)给予APP5肽类似物165灌胃干预,其余两组以蒸馏水代替。3周后应用Morris水迷宫、免疫组织化学和Western blotting方法检测大鼠的学习记忆能力及PSD95和Shank1的表达。结果5肽类似物165治疗组大鼠的平均游泳时间较模型组明显缩短(P<0.01),且海马PSD95和Shank1阳性神经细胞数及PSD95和Shank1蛋白表达较模型组明显增加(P<0.05)。结论5肽类似物165可显著提高大鼠学习记忆能力,增加大鼠海马PSD95和Shank1表达,表明其对突触功能和可塑性具改善作用。展开更多
文摘The problems of movement apparatus in children, youth and even adolescents aren’t connected with “a weakness of muscles” but with a shortening of muscles, tendons, and capsules which in orthopaedic literature is called “contracture” [1] [2] [3] [4]. The older way of thinking about the problem was based on the conviction that “weak muscles” cause and make problems;we, however, present on many examples that “restriction of movements” doing by shortening of soft tissues makes contracture and incorrect position of joints, body parts, the serious and frequent clinical problems.
文摘[Objectives]The paper was to explore the prevention and therapeutic schedule of tobacco black shank.[Methods]Different concentrations of 25 g/L fludioxonil·37.5 g/L metalaxyl-M,10 billion/mL Bacillus amyloliquefaciens,110 g/L amino acids·24 g/L manganese zinc,120 g/L calcium·20 g/L magnesium,and 4%metalaxyl-M·64%mancozeb were employed to assess their efficacy in controlling tobacco black shank.The disease index was subsequently evaluated.[Results]25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+110 g/L amino acids·24 g/L manganese zinc(transplanting dosage)or 120 g/L calcium·20 g/L magnesium(sealing dosage)(transplanting dosage:750 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2,sealing dosage:1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2)resulted in a notable impact on the prevention of tobacco black shank.The incidence in the treated area was 10.78%,a 35.72%reduction compared to the control.The estimated yield was 99700 yuan/hm 2,a 34.91%increase compared to the control.25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+120 g/L calcium·20 g/L magnesium+4%metalaxyl-M·64%mancozeb(control dosage:1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2+1.5×103 g/hm 2,1.5×103 mL/hm 2+1.2×104 mL/hm 2+1.5×103 mL/hm 2+1.5×103 g/hm 2,with an interval of 7 d between applications)demonstrated a significant efficacy in controlling tobacco black shank.At 7 d following the second application,the relative preventive efficacy was observed to be 88.99%.Additionally,the estimated yield was 109900 yuan/hm 2,representing an increase of 244.51%compared to the control.[Conclusions]During the transplanting and sealing stages,25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+110 g/L amino acids·24 g/L manganese zinc(transplanting dosage)or 120 g/L calcium·20 g/L magnesium(sealing dosage)may be employed to enhance the growth of tobacco plants and mitigate the occurrence of tobacco black shank.Additionally,25 g/L fludioxonil·37.5 g/L metalaxyl-M+10 billion/mL B.amyloliquefaciens+120 g/L calcium·20 g/L magnesium+4%metalaxyl-M·64%mancozeb can be utilized for the treatment of tobacco black shank during the initial incidence stage.
文摘目的观察5肽类似物165对老年性痴呆(Alzhei mer disease,AD)模型大鼠学习记忆能力及突触后致密区蛋白95(postsynaptic density95,PSD95)和骨架蛋白Shank1表达的影响。方法将45只大鼠随机分为正常对照组、模型组和5肽类似物165治疗组,模型组和治疗组大鼠按体重3mg/kg行双侧侧脑室链脲佐菌素(streptozotocin,STZ)注射,第3天重复注射建立AD模型,对照组以人工脑脊液代替STZ。术后21d治疗组按体重0.34mg/(kg.d)给予APP5肽类似物165灌胃干预,其余两组以蒸馏水代替。3周后应用Morris水迷宫、免疫组织化学和Western blotting方法检测大鼠的学习记忆能力及PSD95和Shank1的表达。结果5肽类似物165治疗组大鼠的平均游泳时间较模型组明显缩短(P<0.01),且海马PSD95和Shank1阳性神经细胞数及PSD95和Shank1蛋白表达较模型组明显增加(P<0.05)。结论5肽类似物165可显著提高大鼠学习记忆能力,增加大鼠海马PSD95和Shank1表达,表明其对突触功能和可塑性具改善作用。
