AIM:To compare visual field defects using the Swedish Interactive Thresholding Algorithm(SITA)Fast strategy with SITA Faster strategy,a newly developed time-saving threshold visual field strategy.METHODS:Ninety-three ...AIM:To compare visual field defects using the Swedish Interactive Thresholding Algorithm(SITA)Fast strategy with SITA Faster strategy,a newly developed time-saving threshold visual field strategy.METHODS:Ninety-three participants(60 glaucoma patients and 33 normal controls)were enrolled.One eye from each participant was selected randomly for the study.SITA Fast and SITA Faster were performed using the 24-2 default mode for each test.The differences of visual field defects between the two strategies were compared using the test duration,false-positive response errors,mean deviation(MD),visual field index(VFI)and the numbers of depressed test points at the significant levels of P<5%,<2%,<1%,and<0.5%in probability plots.The correlation between strategies was analyzed.The agreement between strategies was acquired by Bland-Altman analysis.RESULTS:Mean test durations were 246.0±60.9 s for SITA Fast,and 156.3±46.3 s for SITA Faster(P<0.001).The test duration of SITA Faster was 36.5%shorter than SITA Fast.The MD,VFI and numbers of depressed points at P<5%,<2%,<1%,and<0.5%in probability plots showed no statistically significant difference between two strategies(P>0.05).Correlation analysis showed a high correlation for MD(r=0.986,P<0.001)and VFI(r=0.986,P<0.001)between the two strategies.Bland-Altman analysis showed great agreement between the two strategies.CONCLUSION:SITA Faster,which saves considerable test time,has a great test quality comparing to SITA Fast,but may be not directly interchangeable.展开更多
Three extraction methods were compared for their efficiency to analyze sitagliptin and simvastatin in rat plasma by LC-MS/MS, including （1） liquid-liquid extraction （LLE）, （2） solid phase extraction （SPE） and ...Three extraction methods were compared for their efficiency to analyze sitagliptin and simvastatin in rat plasma by LC-MS/MS, including （1） liquid-liquid extraction （LLE）, （2） solid phase extraction （SPE） and （3） supported liquid extraction （SLE）. Comparison of recoveries of analytes with different extraction methods revealed that SLE was the best extraction method. The detection was facilitated with ion trap-mass spectrometer by multiple reactions monitoring （MRM） in a positive ion mode with ESI. The transitions monitored were m./z 441.1→325.2 for simvastatin, 408.2→235.1 for sitagliptin and 278.1→260.1 for the IS. The lower limit of quantification （LLOQ） was 0.2 ng/mL for sitagliptin and 0.1 ng/mL for simvastatin. The effective SLE offers enhanced chromatographic selectivity, thus facilitating the potential utility of the method for routine analysis of biological samples along with pharmacokinetic studies.展开更多
Purpose: In this study we evaluated the learning effect in different perimetric programs by performing full threshold to one and SITA-standart to the other eye of the same normal young sub-
Objective: To compare the glaucoma hemifield test (ght) results of the central 30-2 threshold test vs. central 30-2 sita standard test in glaucoma suspect patients without expierence in automated perimetry. Methods: U...Objective: To compare the glaucoma hemifield test (ght) results of the central 30-2 threshold test vs. central 30-2 sita standard test in glaucoma suspect patients without expierence in automated perimetry. Methods: Using the humphrey visual field analyzer model 745, 100 subjects were tested with central 30-2 threshold test (group a) and 100 subjects were tested with cen-展开更多
托马斯·马登先生于2004年加入国际航空电讯集团（SITA）担任副总裁，分管政府/保安能力中心。在该职位上，他在与SITA边界管理与生物识别器材有关的方面，负责制定与政府相关的策略。本刊在参加APS Asia 2006时采访了托马斯·...托马斯·马登先生于2004年加入国际航空电讯集团（SITA）担任副总裁，分管政府/保安能力中心。在该职位上，他在与SITA边界管理与生物识别器材有关的方面，负责制定与政府相关的策略。本刊在参加APS Asia 2006时采访了托马斯·马登先生。展开更多
8月1日上海浦东国际机场（PVG）宣布将在2007年采取重大举措，启用配备来自SITA的一流信息技术解决方案的新航站楼，从而实现于2020年服务1亿旅客的目标。经过激烈的竞争，SITA和上海上实国际贸易（集团）有限公司最终赢得了一项为期4...8月1日上海浦东国际机场（PVG）宣布将在2007年采取重大举措，启用配备来自SITA的一流信息技术解决方案的新航站楼，从而实现于2020年服务1亿旅客的目标。经过激烈的竞争，SITA和上海上实国际贸易（集团）有限公司最终赢得了一项为期4年价值800万美元的合同，为计划于2007年启用的上海浦东国际机场第二航站楼及时配备综合机场管理系统。该项目包括SITA旅客值机系统AirportConnect Common Use Terminal Equipment（CUTE）和行李再确认系统BagManager。展开更多
PURPOSE. To investigate the test- retest variability of multifocal visual evoked potential (mfVEP) and threshold perimetry in glaucoma, and to examine the relationship between the two techniques. METHODS. Data were re...PURPOSE. To investigate the test- retest variability of multifocal visual evoked potential (mfVEP) and threshold perimetry in glaucoma, and to examine the relationship between the two techniques. METHODS. Data were recorded using the AccuMap mfVEP and SITA standard program of the Humphrey Field Analyzer. Data were obtained twice within a 4- week period from both eyes of 74 patients with varying amounts of glaucomatous visual field loss. The number of defective test locations (those falling beyond a given probability value of being normal) were calculated for mfVEP and SITA, using databases incorporated within the instruments software. Reliability measures and test times were recorded along with patient test preference. RESULTS. Both tests showed a large degree of test- retest variability in the number of defective test locations (95% limits of agreement for mfVEP and SITA being 13.39 and 9.88, respectively). A “ fair to moderate” degree of spatial agreement was found between mfVEP and SITA. The number of mfVEP defective locations was dependent on the signal amplitude. No relationship was found between test- retest variability and the reliability indices for either test. The mean time taken to perform mfVEP and SITA standard was 33 and 20 minutes, respectively, and 73 of the 74 patients preferred the mfVEP test. CONCLUSIONS. Test- retest variability was found to be slightly greater for mfVEP. The processing of mfVEP signals needs to be changed to remove the relationship between the number of defective locations and signal amplitude. The majority of patients preferred mfVEP to conventional perimetiy although mfVEP takes longer to perform.展开更多
文摘AIM:To compare visual field defects using the Swedish Interactive Thresholding Algorithm(SITA)Fast strategy with SITA Faster strategy,a newly developed time-saving threshold visual field strategy.METHODS:Ninety-three participants(60 glaucoma patients and 33 normal controls)were enrolled.One eye from each participant was selected randomly for the study.SITA Fast and SITA Faster were performed using the 24-2 default mode for each test.The differences of visual field defects between the two strategies were compared using the test duration,false-positive response errors,mean deviation(MD),visual field index(VFI)and the numbers of depressed test points at the significant levels of P<5%,<2%,<1%,and<0.5%in probability plots.The correlation between strategies was analyzed.The agreement between strategies was acquired by Bland-Altman analysis.RESULTS:Mean test durations were 246.0±60.9 s for SITA Fast,and 156.3±46.3 s for SITA Faster(P<0.001).The test duration of SITA Faster was 36.5%shorter than SITA Fast.The MD,VFI and numbers of depressed points at P<5%,<2%,<1%,and<0.5%in probability plots showed no statistically significant difference between two strategies(P>0.05).Correlation analysis showed a high correlation for MD(r=0.986,P<0.001)and VFI(r=0.986,P<0.001)between the two strategies.Bland-Altman analysis showed great agreement between the two strategies.CONCLUSION:SITA Faster,which saves considerable test time,has a great test quality comparing to SITA Fast,but may be not directly interchangeable.
文摘Three extraction methods were compared for their efficiency to analyze sitagliptin and simvastatin in rat plasma by LC-MS/MS, including （1） liquid-liquid extraction （LLE）, （2） solid phase extraction （SPE） and （3） supported liquid extraction （SLE）. Comparison of recoveries of analytes with different extraction methods revealed that SLE was the best extraction method. The detection was facilitated with ion trap-mass spectrometer by multiple reactions monitoring （MRM） in a positive ion mode with ESI. The transitions monitored were m./z 441.1→325.2 for simvastatin, 408.2→235.1 for sitagliptin and 278.1→260.1 for the IS. The lower limit of quantification （LLOQ） was 0.2 ng/mL for sitagliptin and 0.1 ng/mL for simvastatin. The effective SLE offers enhanced chromatographic selectivity, thus facilitating the potential utility of the method for routine analysis of biological samples along with pharmacokinetic studies.
文摘Purpose: In this study we evaluated the learning effect in different perimetric programs by performing full threshold to one and SITA-standart to the other eye of the same normal young sub-
文摘Objective: To compare the glaucoma hemifield test (ght) results of the central 30-2 threshold test vs. central 30-2 sita standard test in glaucoma suspect patients without expierence in automated perimetry. Methods: Using the humphrey visual field analyzer model 745, 100 subjects were tested with central 30-2 threshold test (group a) and 100 subjects were tested with cen-
文摘8月1日上海浦东国际机场（PVG）宣布将在2007年采取重大举措，启用配备来自SITA的一流信息技术解决方案的新航站楼，从而实现于2020年服务1亿旅客的目标。经过激烈的竞争，SITA和上海上实国际贸易（集团）有限公司最终赢得了一项为期4年价值800万美元的合同，为计划于2007年启用的上海浦东国际机场第二航站楼及时配备综合机场管理系统。该项目包括SITA旅客值机系统AirportConnect Common Use Terminal Equipment（CUTE）和行李再确认系统BagManager。
文摘PURPOSE. To investigate the test- retest variability of multifocal visual evoked potential (mfVEP) and threshold perimetry in glaucoma, and to examine the relationship between the two techniques. METHODS. Data were recorded using the AccuMap mfVEP and SITA standard program of the Humphrey Field Analyzer. Data were obtained twice within a 4- week period from both eyes of 74 patients with varying amounts of glaucomatous visual field loss. The number of defective test locations (those falling beyond a given probability value of being normal) were calculated for mfVEP and SITA, using databases incorporated within the instruments software. Reliability measures and test times were recorded along with patient test preference. RESULTS. Both tests showed a large degree of test- retest variability in the number of defective test locations (95% limits of agreement for mfVEP and SITA being 13.39 and 9.88, respectively). A “ fair to moderate” degree of spatial agreement was found between mfVEP and SITA. The number of mfVEP defective locations was dependent on the signal amplitude. No relationship was found between test- retest variability and the reliability indices for either test. The mean time taken to perform mfVEP and SITA standard was 33 and 20 minutes, respectively, and 73 of the 74 patients preferred the mfVEP test. CONCLUSIONS. Test- retest variability was found to be slightly greater for mfVEP. The processing of mfVEP signals needs to be changed to remove the relationship between the number of defective locations and signal amplitude. The majority of patients preferred mfVEP to conventional perimetiy although mfVEP takes longer to perform.
