Two novel complexes, [Bi（III）（S2CNBn Et）3] 1 and [Bi（III）（S2CNPPPy-2）3] 2, were synthesized and characterized by elemental analysis, IR, ^1H NMR, ^13C NMR, TG-DTG and X-ray single-crystal diffraction. The stru...Two novel complexes, [Bi（III）（S2CNBn Et）3] 1 and [Bi（III）（S2CNPPPy-2）3] 2, were synthesized and characterized by elemental analysis, IR, ^1H NMR, ^13C NMR, TG-DTG and X-ray single-crystal diffraction. The structure reveals that complex 1 belongs to the monoclinic system, space group P21/c with a = 11.457（5）, b = 17.437（8）, c = 33.439（14）, β= 98.499（8）o, Z = 4, V = 6607（5）3, Dc = 1.689 g·cm^-3, F（000） = 3328, μ= 5.742 mm^-1, the final R = 0.0906, w R = 0.1678 and S = 1.032. The structure indicates that complex 2 belongs to the triclinic system, space group P1 with a = 12.608（9）, b = 12.622（8）, c = 12.49（6）, α = 102.652（15）, β = 103.013（14）, γ = 109.698（10）o, Z = 1, V = 1762.3（19）3, Dc = 1.741 g·cm^-3, F（000） = 916, μ = 5.395 mm^-1, the final R = 0.048 2, w R = 0.1206 and S =1.046. In the two complexes, each six-coordinated Bi（III） atom adopts a pentagonal pyramidal configuration with six sulfur atoms from three ligands, and the dimmer structures are formed by weak interactions of Bi···S between two molecules. The anticancer activities of the two complexes were studied by evaluating their cytotoxicities against several human cancer cell lines using the MTT assay. Results indicated complex 2 showed moderate cytotoxic effects on the selected cancer cells.展开更多
基金Supported by the International Cooperation Project of the Science&Technology Agency of Henan Province(No.134300510013)
文摘Two novel complexes, [Bi（III）（S2CNBn Et）3] 1 and [Bi（III）（S2CNPPPy-2）3] 2, were synthesized and characterized by elemental analysis, IR, ^1H NMR, ^13C NMR, TG-DTG and X-ray single-crystal diffraction. The structure reveals that complex 1 belongs to the monoclinic system, space group P21/c with a = 11.457（5）, b = 17.437（8）, c = 33.439（14）, β= 98.499（8）o, Z = 4, V = 6607（5）3, Dc = 1.689 g·cm^-3, F（000） = 3328, μ= 5.742 mm^-1, the final R = 0.0906, w R = 0.1678 and S = 1.032. The structure indicates that complex 2 belongs to the triclinic system, space group P1 with a = 12.608（9）, b = 12.622（8）, c = 12.49（6）, α = 102.652（15）, β = 103.013（14）, γ = 109.698（10）o, Z = 1, V = 1762.3（19）3, Dc = 1.741 g·cm^-3, F（000） = 916, μ = 5.395 mm^-1, the final R = 0.048 2, w R = 0.1206 and S =1.046. In the two complexes, each six-coordinated Bi（III） atom adopts a pentagonal pyramidal configuration with six sulfur atoms from three ligands, and the dimmer structures are formed by weak interactions of Bi···S between two molecules. The anticancer activities of the two complexes were studied by evaluating their cytotoxicities against several human cancer cell lines using the MTT assay. Results indicated complex 2 showed moderate cytotoxic effects on the selected cancer cells.
