期刊文献+
共找到10,498篇文章
< 1 2 250 >
每页显示 20 50 100
Disturbance failure mechanism of highly stressed rock in deep excavation:Current status and prospects
1
作者 Tao Wang Weiwei Ye +3 位作者 Liyuan Liu Kai Liu Naisheng Jiang Xianhui Feng 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第4期611-627,共17页
This article reviews the current status on the dynamic behavior of highly stressed rocks under disturbances.Firstly,the experimental apparatus,methods,and theories related to the disturbance dynamics of deep,high-stre... This article reviews the current status on the dynamic behavior of highly stressed rocks under disturbances.Firstly,the experimental apparatus,methods,and theories related to the disturbance dynamics of deep,high-stress rock are reviewed,followed by the introduction of scholars’research on deep rock deformation and failure from an energy perspective.Subsequently,with a backdrop of highstress phenomena in deep hard rock,such as rock bursts and core disking,we delve into the current state of research on rock microstructure analysis and residual stresses from the perspective of studying the energy storage mechanisms in rocks.Thereafter,the current state of research on the mechanical response and the energy dissipation of highly stressed rock formations is briefly retrospected.Finally,the insufficient aspects in the current research on the disturbance and failure mechanisms in deep,highly stressed rock formations are summarized,and prospects for future research are provided.This work provides new avenues for the research on the mechanical response and damage-fracture mechanisms of rocks under high-stress conditions. 展开更多
关键词 deep rock with high stress highly stressed rock rock failure residual stress energy release
下载PDF
Stressed Coral Reef Identification Using Deep Learning CNN Techniques
2
作者 S.P.Aruna M.Thamarai 《Journal of Electronic & Information Systems》 2023年第2期1-9,共9页
Deep learning is a machine learning technique that allows the computer to process things that occur naturally to humans.Today,deep learning techniques are commonly used in computer vision to classify images and videos... Deep learning is a machine learning technique that allows the computer to process things that occur naturally to humans.Today,deep learning techniques are commonly used in computer vision to classify images and videos.As a result,for challenging computer vision problems,deep learning provides state of the art solutions to it.Coral reefs are an essential resource of the earth.A new study finds the planet has lost half of its coral reefs since 1950.It is necessary to restore and prevent damage to coral reefs as they play an important role in maintaining a balance in the marine ecosystem.This proposed work helps to prevent the corals from bleaching and restore them to a healthy condition by identifying the root cause of the threats.In the proposed work,using deep learning CNN techniques,the images are classified into Healthy and Stressed coral reefs.Stressed coral reefs are an intermediate state of coral reef between healthy and bleached coral reefs.The pre-trained models Resnet50 and Inception V3 are used in this study to classify the images.Also,a proposed CNN model is built and tested for the same.The results of Inception V3 and Resnet50 are improved to 70%and 55%by tuning the hypermeters such as dropouts and batch normalisation.Similarly,the proposed model is tuned as required and obtains a maximum of up to 90%accuracy.With large datasets,the optimum amount of neural networks and tuning it as required brings higher accuracy than other methods. 展开更多
关键词 stressed coral reef Deep learning Convolutional neural network Pre-trained models
下载PDF
Antiplane shear crack in a prestressed elastic medium based on the couple stress theory
3
作者 Jian CHEN Yawei WANG Xianfang LI 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2023年第4期583-602,共20页
A prestressed elastic medium containing a mode-Ⅲcrack is studied by means of the couple stress theory(CST).Based on the CST under initial stresses,a governing differential equation along with a mixed boundary value p... A prestressed elastic medium containing a mode-Ⅲcrack is studied by means of the couple stress theory(CST).Based on the CST under initial stresses,a governing differential equation along with a mixed boundary value problem is established.The singularities of the couple stress and force stress near the crack tips are analyzed through the asymptotic crack-tip fields resulting from the characteristic expansion method.To determine their intensity,a hypersingular integral equation is derived and numerically solved with the help of the Chebyshev polynomial.The obtained results show a strong size-dependence of the out-of-plane displacement on the crack and the couple stress intensity factor(CSIF)and the force stress intensity factor(FSIF)around the crack tips.The symmetric part of the shear stress has no singularity,and the skew-symmetric part related to the couple stress exhibits an r^(-3/2)singularity,in which r is the distance from the crack tip.The initial stresses also affect the crack tearing displacement and the CSIF and FSIF. 展开更多
关键词 couple stress theory(CST) initial stress antiplane shear crack SINGULARITY hypersingular integral equation
下载PDF
Prestressed tensioning method and its application to testing anchor stress of anchor cables for side-slope stabilization 被引量:3
4
作者 张朋 LONG Yan-cheng LUO Bing 《Journal of Chongqing University》 CAS 2017年第1期38-50,共13页
The anchor stress extent of a prestress anchor cable project has a direct relation with the project safety and performance. Prestressed tensioning method is a kind of nondestructive testing method, by which a reverse ... The anchor stress extent of a prestress anchor cable project has a direct relation with the project safety and performance. Prestressed tensioning method is a kind of nondestructive testing method, by which a reverse stretching load is applied on the external exposure section of anchor cable under construction or in service, and then the elongation variation of stress bars is measured to determine the anchor stress. We elaborated the theory and testing mechanism of prestressed tensioning method, and systematically studied key issues during the prestressed tensioning process of anchor cable by using physical model test, including the composition of tension stress-elongation curve, the variation of anchor stress, the compensation of locked anchor stress, and the judgment of anchor stress, and verified the theory feasibility of prestressed tensioning method. A case study on slope anchor cable of one highway project was conducted to further discuss on the test method, operation procedures and judgment of prestressed tensioning method on obtaining anchor stress, and then the test data of three situations were analyzed. The result provides a theoretical basis and technical base for the application of prestressed tensioning method to the evaluation of construction quality and operation conditions of anchor cable project. 展开更多
关键词 anchor cable anchor stress prestressed tensioning method model test
下载PDF
Methods for obtaining two way memory effect and stressed two way memory effect of CuAlNi single crystals 被引量:1
5
作者 陈庆福 赵连城 《中国有色金属学会会刊:英文版》 CSCD 2001年第1期10-17,共8页
Various training methods for two way memory effect (TWME) and stressed two way memory effect (STWME) were tried on Cu 13.4Al 4.0Ni (mass fraction, %) single crystals by applying tensile stress along 〈001〉 direction ... Various training methods for two way memory effect (TWME) and stressed two way memory effect (STWME) were tried on Cu 13.4Al 4.0Ni (mass fraction, %) single crystals by applying tensile stress along 〈001〉 direction of β phase. The training method of cooling with load can induce a lot of martensite prone to stabilize, thus cause large residual deformation, wide hysteresis and small TWME. Training with constant load can produce STWME larger than 8% with the least residual deformation. By training procedure of martensite reorientation below M f followed by thermal cycling, the TWME is relatively large with very small residual deformation and with comparatively narrow hysteresis of two way memory. The obtained two way memory curve after such training is not a closed loop, and the obtained TWME is not stable. However, these can be improved by thermal cycling. Training with martensite reorientation below M f and thermal cycling under relatively low constant stress throughout the whole training procedure is the optimum way of obtaining TWME, and more than 1.7% TWME can be obtained. The thermomechanical history of the sample has a pronounced effect on the training result. Thermomechanical cycling has a softening effect on martensite. [ 展开更多
关键词 training TWO WAY MEMORY EFFECT stressed TWO WAY MEMORY EFFECT CU-AL-NI single crystal
下载PDF
Fatigue Damage Modeling for Partially Prestressed Concrete Beams under Repeated Loadings with Variable Amplitude 被引量:2
6
作者 冯秀峰 宋玉普 朱美春 《Journal of Southwest Jiaotong University(English Edition)》 2006年第3期258-264,共7页
A full-range nonlinear analysis method for fatigue damage in prestressed concrete beams is presented. New damage accumulation models are proposed to describe the fatigue damage evolution in concrete and reinforcement ... A full-range nonlinear analysis method for fatigue damage in prestressed concrete beams is presented. New damage accumulation models are proposed to describe the fatigue damage evolution in concrete and reinforcement respectively. Based on the stress analysis for cross section, the stress redistrbution in the fatigue damage process, due to the different damage mechanisms of concrete and reinforcement, is considered. The nonlinear damage analysis is achieved by means of piecewise linearity, and it is applicable on the condition of repeated loadings with variable amplitude. Fatigue damage modeling of a beam is implemented to illustrate that the proposed method can preferably fit the experimental results. 展开更多
关键词 Prestressed concrete beam FATIGUE DAMAGE Nonlinear analysis Stress redistribution
下载PDF
Long-Term Bending Behaviour of Prestressed Glulam Bamboo-Wood Beam Based on Creep Effect 被引量:1
7
作者 Nan Guo Huajing Xiong +4 位作者 Mingtao Wu Hongliang Zuo Fengguo Jiang Xiaofeng Hou Dabo Xin 《Structural Durability & Health Monitoring》 EI 2020年第3期229-248,共20页
Creep is an important characteristic of bamboo and wood materials under long-term loading.This paper aims to study the long-term bending beha-viour of prestressed glulam bamboo-wood beam(GBWB).For this,14 pre-stressed... Creep is an important characteristic of bamboo and wood materials under long-term loading.This paper aims to study the long-term bending beha-viour of prestressed glulam bamboo-wood beam(GBWB).For this,14 pre-stressed GBWBs were selected and subjected to a long-term loading test for 60 days.Then,a comparative analysis was performed for the effects of pre-tension values,the number of pre-stressed wires,and long-term load on the stress variation of the steel wire and the long-term deflection of the beam midspan.The test results showed that with the number of prestressed wires increasing,the total stress of the steel wire in the beam midspan and the ratio of the long-term deflec-tion to the total deflection decreases decreased,but when the number of steel wires exceeded 4,the total stress and long-term deflection was less infuenced;with the pre-tension value increasing,the ratio of the total stress of the steel wire in the beam midspan and the ratio of the long-temm deflection to the total deflec-tion also decreased,but when the prestress force was greater than 3.975 kN,the:total stress and long-term deflection were less affected;with the other parameters unchanged,when the value of the long-term load increased,the total stress of the steel wire decreased,and the long-temm deflection of the beam midspan increased,which shall be more significant with the long-term load greater than 30%of the standard ultimate bearing capacity.After the test,the experimental data were fitted,and the creep coefficient was given.Finally,the long-term stiffness calcula-tion fommula of the pre-stressed GBWB based on creep effect was proposed.The research findings have certain theoretical significance and engineering value. 展开更多
关键词 Prestressed glulam bamboo-wood beam long-temn loading test steel wire stress long-term deflection creep cofficient
下载PDF
Fully Stressed Design of Fink Truss Using STAAD.Pro Software 被引量:1
8
作者 Avanti Patrikar K. K. Pathak 《Open Journal of Civil Engineering》 2016年第4期631-642,共12页
This paper presents study of optimization of Fink Truss by Fully Stressed Design (FSD) method using STAAD.Pro software version STAAD.Pro V8i (SELECT series 5). Three spans of the trusses have been considered and each ... This paper presents study of optimization of Fink Truss by Fully Stressed Design (FSD) method using STAAD.Pro software version STAAD.Pro V8i (SELECT series 5). Three spans of the trusses have been considered and each truss has been subjected to 27 types of load cases by changing nodal load locations. Central node load has been kept constant in each truss as 100 kN. Three sets of load condition is taken, viz, 100 kN, 120 kN and 150 kN. Total 81 trusses have been analyzed in this study to achieve a target stress of 100 MPa. Steel take-off for each case and maximum displacement for each case have been calculated and compared in this study and it shows that weight does not always increase with increase in the span or height. Results of the study could be helpful in designing a truss that does not waste material. 展开更多
关键词 Fink Truss GEOMETRY PROPERTY STAAD Parameters DISPLACEMENT Fully stressed Design
下载PDF
Web Shear Strengthening Technique of Deep Precast Prestressed Hollow Core Slabs under Truck Loads
9
作者 Islam M. Ezz El-Arab 《Journal of Building Construction and Planning Research》 2017年第4期129-145,共17页
Precast prestressed Hollow Core Slabs (HCS), are one of the famous and widely used slabs for concrete structures all over the world and widely implemented in the Middle East. HCS are used in industrial, commercial, re... Precast prestressed Hollow Core Slabs (HCS), are one of the famous and widely used slabs for concrete structures all over the world and widely implemented in the Middle East. HCS are used in industrial, commercial, residential buildings, as well as, in the parking structures. This paper succeeded to present new special details for deep HCS to enhance and strengthen the web shear strength capacity of HCS 400 and 500 mm depths respectively at the open parking area. This is subjected to heavy truck wheel loads so as to achieve the LRFD Code’s requirements. However, it is noticed many web shear cracks of HCS are used at parking area at many projects in Gulf Region. On the other hand, ACI318-14 permits no shear reinforcement in prestressed HCS thickness of less than 12.5 in (320 mm). The paper presents experimental tests program, to verify the numerical finite element of deep HCS under maximum design uniform loads, in addition to the new strengthening techniques. New strengthening techniques succeed to enhance the web shear capacity by significant percentage, due to the new details for HCS 400 by 68% up to 256% increasing of the web shear capacity compared to the ordinary HCS section. Also, HCS 500 shear capacity is enhanced with different percentages of strengthening techniques by 55%, up to 197% based on the different cases of strengthening. Furthermore enhancing deep HCS shear performance;the new techniques have an advantage of an easy execution at the site;casting with structural topping, otherwise the preparation can be done in precast factory before site handover, which saves time and cost compared to the others traditional strengthening techniques. 展开更多
关键词 HOLLOW Core SLABS SHEAR Stress PREstressed SLABS SHEAR Strength
下载PDF
Stress Analysis of New Type Pre-Stressed Anchor Bearing Plate Combining Stamping with Welding Forming and Its Anchorage Zone
10
作者 Daosen Chen Nianchun Deng +1 位作者 Zanzhi Wang Haining Zuo 《World Journal of Engineering and Technology》 2017年第4期33-41,共9页
An anchor bearing plate transfers the anchoring force from anchor plate to the concrete and the pre-stress is formed in the concrete structure. Currently, the main type of anchor bearing plate is cast iron. It is brit... An anchor bearing plate transfers the anchoring force from anchor plate to the concrete and the pre-stress is formed in the concrete structure. Currently, the main type of anchor bearing plate is cast iron. It is brittle during transportation and tension process. This paper presents a new type of anchor bearing plate combined stamping with welding forming. The structure of the new type anchor bearing plate is introduced. The stress states of the anchor bearing plate and anchorage zone under work are studied. Various specifications of anchor bearing plate are studied by ANSYS finite element analysis software following the AASHTO specification. The analysis results are compared with the results of the same type of OVM round-shaped anchor plate. The study results show that the new pre-stressed anchor plates combined stamping with welding forming are feasible and more sturdy which can meet the engineering demand. 展开更多
关键词 Pre-stressed Concrete Structure Finite Element Analysis ANCHOR BEARING Plate Stress of ANCHORAGE Zone
下载PDF
Comparative proteomic analysis of hippocampal proteins from chronic stressed rats
11
作者 Liang WANG1,Zhi-Hua YANG2,Xi-Zheng ZHANG1(1.Institute of Medical Equipment,Tianjin 300161,2Institute of Health & Environmental Medicine,Tianjin 300050) 《医用生物力学》 EI CAS CSCD 2009年第S1期94-94,共1页
Chronic stress can induce hippocampus injury such as neuron loss and dendrite atrophy,but its mechanism and molecular basis remain unclear up to now.To understand the molecular mechanism on protein level and find the ... Chronic stress can induce hippocampus injury such as neuron loss and dendrite atrophy,but its mechanism and molecular basis remain unclear up to now.To understand the molecular mechanism on protein level and find the crucial proteins which correlated with chronic 展开更多
关键词 Comparative proteomic analysis of hippocampal proteins from chronic stressed rats
下载PDF
That Jiang Zemin Stressed China Must Further Expand Opening to Outside World after WTO Entry
12
《China's Foreign Trade》 2002年第11期2-3,共2页
关键词 WTO World That Jiang Zemin stressed China Must Further Expand Opening to Outside World after WTO Entry
下载PDF
REAL EFFECTS & DIVERSITY TO BE STRESSED IN INTERNATIONAL COOPERATION
13
作者 Zheng Chongzhi and Mao Guoqing(Shanghai Institute of Organic Chemistry, CAS) 《Bulletin of the Chinese Academy of Sciences》 1997年第1期88-90,共3页
In recent years, the Shanghai Institute of Organic Chemistry under the CAS has freed itself from the stereotyped rut of conventional forms in its external intercourse while still sticking fast to upholding its strateg... In recent years, the Shanghai Institute of Organic Chemistry under the CAS has freed itself from the stereotyped rut of conventional forms in its external intercourse while still sticking fast to upholding its strategic goal of disciplinary development. Our stress in this aspect has shifted to the pursuit of real effects and diversified forms in international S&T exchange. Our exploration features the following four characteristics: 展开更多
关键词 DIVERSITY TO BE stressed IN INTERNATIONAL COOPERATION REAL EFFECTS CAS US BE
下载PDF
Development of Coalbed Methane Resources Stressed in China
14
《China Oil & Gas》 CAS 1997年第1期43-43,共1页
关键词 Development of Coalbed Methane Resources stressed in China
下载PDF
Environmental Protection Stressed in Weizhou Oilfield of South China Sea
15
《China Oil & Gas》 CAS 1997年第4期205-205,共1页
关键词 Environmental Protection stressed in Weizhou Oilfield of South China Sea
下载PDF
Modulatory effect of pineapple peel extract on lipid peroxidation,catalase activity and hepatic biomarker levels in blood plasma of alcoholinduced oxidative stressed rats 被引量:13
16
作者 Okafor OY Erukainure OL +3 位作者 Ajiboye JA Adejobi RO Owolabi FO Kosoko SB 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2011年第1期12-14,共3页
Objective:To investigate the ability of the methanolic extract of pineapple peel to modulate alcohol-induced lipid peroxidation,changes in catalase activities and hepatic biochemical marker levels in blood plasma.Meth... Objective:To investigate the ability of the methanolic extract of pineapple peel to modulate alcohol-induced lipid peroxidation,changes in catalase activities and hepatic biochemical marker levels in blood plasma.Methods:Oxidative stress was induced by oral administration of ethanol(20%w/v) at a dosage of 5 niL/kg bw in rats.After 28 days of treatment,the rats were fasted overnight and sacrificed by cervical dislocation.Blood was collected with a 2 mL syringe by cardiac puncture and was centrifuged at 3000 rpm for 10 min.The plasma was analyzed to evaluate malondialdehyde(MDA),catalase activity,aspartate aminotransferase(AST),alkaline phosphatase(ALP) and alanine aminotransferase(ALT) concentrations.Results:Administration of alcohol caused a drastic increase(87.74%) in MDA level compared with the control.Pineapple peel extract significantly reduced the MDA level by 60.16%at 2.S mL/kg bw.Rats fed alcohol only had the highest catalase activity,treatment with pineapple peel extract at 2.5 mL/kg bw however, reduced the activity.Increased AST,ALP and ALT activities were observed in rats fed alcohol only respectively,treatment with pineapple peel extract drastically reduced their activities. Conclusions:The positive modulation of lipid peroxidation,catalase activities as well as hepatic biomarker levels of blood plasma by the methanolic extract of pineapple peels under alcoholinduced oxidative stress is an indication of its protective ability in the management of alcoholinduced toxicity. 展开更多
关键词 Blood PLASMA Catalase LIPID peroxide Aspartate AMINOTRANSFERASE Alkaline phosphatase Alanine AMINOTRANSFERASE HEPATIC BIOMARKER Pineapple peel EXTRACT Oxidative stress LIPID peroxidation
下载PDF
PROPAGATION OF LOVE WAVES IN PRESTRESSED PIEZOELECTRIC LAYERED STRUCTURES LOADED WITH VISCOUS LIQUID 被引量:7
17
作者 Jianke Du Kai Xian +1 位作者 Ji Wang Yook-Kong Yong 《Acta Mechanica Solida Sinica》 SCIE EI 2008年第6期542-548,共7页
We investigate analytically the effect of initial stress in piezoelectric layered structures loaded with viscous liquid on the dispersive and attenuated characteristics of Love waves, which involves a thin piezoelectr... We investigate analytically the effect of initial stress in piezoelectric layered structures loaded with viscous liquid on the dispersive and attenuated characteristics of Love waves, which involves a thin piezoelectric layer bonded perfectly to an unbounded elastic substrate. The effects of initial stress in the piezoelectric layer and the viscous coefficient of the liquid on the phase velocity of Love waves are analyzed. Numerical results are presented and discussed. The analytical method and the results can be useful for the design of chemical and biosensing liquid sensors. 展开更多
关键词 Love waves PIEZOELECTRIC viscous liquid initial stress
下载PDF
Milk production and composition and metabolic alterations in the mammary gland of heat-stressed lactating dairy cows 被引量:4
18
作者 FAN Cai-yun SU Di +5 位作者 TIAN He HU Rui-ting RAN Lei YANG Ying SU Yan-jing CHENG Jian-bo 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2019年第12期2844-2853,共10页
This experiment was conducted to investigate the effects of heat stress(HS) on the feed intake, milk production and composition and metabolic alterations in the mammary gland of dairy cows. Twenty Holstein cows were r... This experiment was conducted to investigate the effects of heat stress(HS) on the feed intake, milk production and composition and metabolic alterations in the mammary gland of dairy cows. Twenty Holstein cows were randomly assigned to one of two treatments according to a completely randomized design. Half of the cows were allocated to the HS group in August(summer season), and the other half were assigned to the HS-free group in November(autumn season). HS reduced(P<0.01) dry matter intake(DMI), milk yield, milk protein and milk urea nitrogen(MUN) of cows compared with HSfree control, but increased(P<0.01) milk somatic cell counts(SCC). We determined the HS-induced metabolic alterations and the relevant mechanisms in dairy cows using liquid chromatography mass spectrometry combined with multivariate analyses. Thirty-four metabolites were identified as potential biomarkers for the diagnosis of HS in dairy cows. Ten of these metabolites, glucose, lactate, pyruvate, lactose, β-hydroxybutyrate, citric acid, α-ketoglutarate, urea, creatine, and orotic acid, had high sensitivity and specificity for HS diagnoses, and seven metabolites were also identified as potential biomarkers of HS in plasma, milk, and liver. These substances are involved in glycolysis, lactose, ketone, tricarboxylic acid(TCA), amino acid and nucleotide metabolism, indicating that HS mainly affects lactose, energy and nucleotide metabolism in the mammary gland of lactating dairy cows. This study suggested that HS might affect milk production and composition by affecting the feed intake and substance metabolisms in the mammary gland tissue of lactating dairy cows. 展开更多
关键词 MILK production metabolomics MAMMARY GLAND heat stress DAIRY COWS
下载PDF
Detection of HSP mRNA Transcription in Transport Stressed Pigs by Fluorescence Quantitative RT-PCR 被引量:6
19
作者 LI Yu-bao BAO En-dong +1 位作者 WANG Zhi-liang ZHAO Ru-qian 《Agricultural Sciences in China》 CAS CSCD 2007年第3期361-367,共7页
The RNA transcripted in vitro was used as the standard quantitative template to make the standard curve and establish the fluorescence quantitative RT-PCR (FQ-PCR) method. By means of FQ-PCR, the transcription chang... The RNA transcripted in vitro was used as the standard quantitative template to make the standard curve and establish the fluorescence quantitative RT-PCR (FQ-PCR) method. By means of FQ-PCR, the transcription changes of HSP70 and HSP90 mRNA in the livers and hearts of transport stressed pigs were studied. The level of HSP70 mRNA transcription increased continuously from the beginning of transportation. The inductions of HSP70 mRNA transcription in the livers and hearts of 10 h transport stressed pigs were 2.5 and 4.1 times higher than that of the un-transport stressed pigs (P〈0.01). However, the transcription levels of HSP90 mRNA in the livers and hearts decreased with the transport stress. 展开更多
关键词 heat shock protein SYBR Green I FQ-PCR transport stress PIGS
下载PDF
Baicalin influences the dendritic morphology of newborn neurons in the hippocampus of chronically stressed rats 被引量:6
20
作者 Xinghua Jiang Junmei Xu +2 位作者 Dingquan Zou Lin Yang Yaping Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第6期496-505,共10页
Chronic stress models, established in adult Sprague-Dawley rats through a 14-day subcutaneous injection of 40 mg/kg corticosterone, once per day, were given a daily oral feeding of 50 mg/kg baicalin. The study was an ... Chronic stress models, established in adult Sprague-Dawley rats through a 14-day subcutaneous injection of 40 mg/kg corticosterone, once per day, were given a daily oral feeding of 50 mg/kg baicalin. The study was an attempt to observe the effect of baicalin on neurogenesis in chronically stressed rats. Results showed that subcutaneous injection of corticosterone significantly decreased the total number of doublecortin-positive neurons in the hippocampus. The reduced cell number caused by corticosterone was mainly due to the decrease of class II doublecortin-positive neurons, but the class I doublecortin-positive neurons were unaffected. Baicalin treatment increased the number of both class I and class II doublecortin-positive neurons. In addition, doublecortin-positive neurons showed less complexity in dendritic morphology after corticosterone injection, and this change was totally reversed by baicalin treatment. These findings suggest that baicalin exhibits a beneficial effect on adult neurogenesis. 展开更多
关键词 neural regeneration traditional Chinese medicine neurogenesis neurodegenerative disease BAICALIN stress HIPPOCAMPUS NEURONS doubiecortin DENDRITES cognition mood regulation grants-supported paper photographs-containing paper neuroregeneration
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部