Sacroiliac joint malposition is one of the main causes evoking lumbocrural pain. Because its clinical symptoms are similar to those induced either by lumbar intervertebral disc protrusion or by ankylosing spondylitis ...Sacroiliac joint malposition is one of the main causes evoking lumbocrural pain. Because its clinical symptoms are similar to those induced either by lumbar intervertebral disc protrusion or by ankylosing spondylitis （AS） at the early stage, and because X-ray results taken at its early stage were not evident for differentiating the diseases,展开更多
To explore the significance of sacroiliac joint aerocele in the diagnosis of ankylosing spondylitis, the data of 196 patients with ankylosing spondylitis (AS) were collected during December of 2008 to May of 2009. And...To explore the significance of sacroiliac joint aerocele in the diagnosis of ankylosing spondylitis, the data of 196 patients with ankylosing spondylitis (AS) were collected during December of 2008 to May of 2009. And 50 patients with osteoarthritis (OA), 15 patients with sclerosing osteitis (SO) and 47 patients with sacroiliac joint tumors were investigated as the control groups. The feature of sacroiliac joint aerocele in computed tomography (CT) images was observed carefully. In AS group there were 130 patients (66.3%) diagnosed as AS according to CT results, and 32 of them (24.6%) were observed with aerocele within sacroiliac joint cavity, majority of whom were earlier AS patients with slight bone destruction. Other 66 patients were diagnosed as early AS according to magnetic resonance imaging (MRI) and ultrasonography. CT examination showed that the 66 patients did not have apparent bone destruction, of whom, 26 (39.4%) patients had aerocele within sacroiliac joint cavity. Among the control groups of 15 (15/50, 30.0%) patients with OA, 5 (5/15, 33.3%) patients with SO were observed sacroiliac joint aerocele. The 47 patients with sacroiliac joint tumors were observed with bone or cartilage destruction, but without signs of sacroiliac joint aerocele. The sacroiliac joint aerocele in CT images of AS patients usually appeared as spots, streaks, small or larger round blocks, and it often happened in patients with earlier stage of diseases. Sacroiliac joint aerocele may be useful to early diagnosis of AS.展开更多
Background With the advanced MRI techniques, pathologic features can be detected at an early stage and quantitatively evaluated, resulting in the advantages of early diagnosis and prompt treatment. This study aimed to...Background With the advanced MRI techniques, pathologic features can be detected at an early stage and quantitatively evaluated, resulting in the advantages of early diagnosis and prompt treatment. This study aimed to determine the value of diffusion-weighted MR imaging （DWI） in detection of early ankylosing spondylitis （AS） and investigate the characteristic manifestations of AS on whole body DWl （WB-DWl）. Methods Twenty patients with the diagnosis of early AS, twenty patients with low back pain （LBP）, and twenty-five healthy volunteers were included in this study. The subchondral bone apparent diffusion coefficients （ADC） among these groups in the bilateral ilia and sacrum along the sacroiliac joints were compared. An independent sample t-test was utilized to analyze ADC value differences among groups. P-values less than 0.05 denoted statistical significance. The mean ADC values of focal DWl lesions in AS patients were also measured. Whole body diffusion-weighted imaging was performed in fifteen additional AS patients, and analyzed with MIP and MPR techniques in comparison to conventional MR images in order to evaluate the ability to detect AS lesions with whole body DWI. Results Mean ADC values in AS patients were （0.518±0.122）×10^-3 mm2/s in the ilium and （0.503＋0.168）x103 mm2/s in the sacrum. These were significantly greater than the values measured in the ilium and sacrum of LBP patients, （0.328±0.053）×10^-3 mm2/s in the ilium and （0.311±0.081）×10^-3 m2/s in the sacrum, and control group, （0.325±0.015）×10-3 mm2/s in the ilium and （0.318±0.011）×10^-3 mm2/s in the sacrum respectively. No statistically significant differences were found between LBP group and control group. The mean ADC value of focal DWI lesions in early AS patients was （0. 899±0.265）×10^-3 mm2/s, which was significantly higher than that of adjacent normal-appearance areas （（0.454±0.079）×10^-3 mm2/s）. WB-DWl detected abnormalities in the 15 additional AS patients both within the sacroiliac joints and at other sites mean ADC value of focal DWl lesions of this patient （1.220±0.299） ×10^-3 mm2/s in the ilium. corresponding to the clinical symptoms of the patients. The cohort was （1.286±0.311）×10^-3 mm2/s in the sacrum and Conclusions Subchondral marrow ADC values of subchondral marrows near the sacroiliac joints allow for the differentiation of patients with early AS from normal volunteers and LBP patients. Combined with post-processing techniques such as MIP and MPR, WB-DWl allows for the comprehensive assessment of AS patients, an evaluation potentially helpful in determining prognosis and following the therapeutic response.展开更多
文摘Sacroiliac joint malposition is one of the main causes evoking lumbocrural pain. Because its clinical symptoms are similar to those induced either by lumbar intervertebral disc protrusion or by ankylosing spondylitis （AS） at the early stage, and because X-ray results taken at its early stage were not evident for differentiating the diseases,
基金the Program for Excellent Young Talents of the Shanghai Sixth People’s Hospital (No. 1402)
文摘To explore the significance of sacroiliac joint aerocele in the diagnosis of ankylosing spondylitis, the data of 196 patients with ankylosing spondylitis (AS) were collected during December of 2008 to May of 2009. And 50 patients with osteoarthritis (OA), 15 patients with sclerosing osteitis (SO) and 47 patients with sacroiliac joint tumors were investigated as the control groups. The feature of sacroiliac joint aerocele in computed tomography (CT) images was observed carefully. In AS group there were 130 patients (66.3%) diagnosed as AS according to CT results, and 32 of them (24.6%) were observed with aerocele within sacroiliac joint cavity, majority of whom were earlier AS patients with slight bone destruction. Other 66 patients were diagnosed as early AS according to magnetic resonance imaging (MRI) and ultrasonography. CT examination showed that the 66 patients did not have apparent bone destruction, of whom, 26 (39.4%) patients had aerocele within sacroiliac joint cavity. Among the control groups of 15 (15/50, 30.0%) patients with OA, 5 (5/15, 33.3%) patients with SO were observed sacroiliac joint aerocele. The 47 patients with sacroiliac joint tumors were observed with bone or cartilage destruction, but without signs of sacroiliac joint aerocele. The sacroiliac joint aerocele in CT images of AS patients usually appeared as spots, streaks, small or larger round blocks, and it often happened in patients with earlier stage of diseases. Sacroiliac joint aerocele may be useful to early diagnosis of AS.
基金This study was supported by grants from the National Natural Science Foundation of China （No. 30870701 and No. 81071133）.
文摘Background With the advanced MRI techniques, pathologic features can be detected at an early stage and quantitatively evaluated, resulting in the advantages of early diagnosis and prompt treatment. This study aimed to determine the value of diffusion-weighted MR imaging （DWI） in detection of early ankylosing spondylitis （AS） and investigate the characteristic manifestations of AS on whole body DWl （WB-DWl）. Methods Twenty patients with the diagnosis of early AS, twenty patients with low back pain （LBP）, and twenty-five healthy volunteers were included in this study. The subchondral bone apparent diffusion coefficients （ADC） among these groups in the bilateral ilia and sacrum along the sacroiliac joints were compared. An independent sample t-test was utilized to analyze ADC value differences among groups. P-values less than 0.05 denoted statistical significance. The mean ADC values of focal DWl lesions in AS patients were also measured. Whole body diffusion-weighted imaging was performed in fifteen additional AS patients, and analyzed with MIP and MPR techniques in comparison to conventional MR images in order to evaluate the ability to detect AS lesions with whole body DWI. Results Mean ADC values in AS patients were （0.518±0.122）×10^-3 mm2/s in the ilium and （0.503＋0.168）x103 mm2/s in the sacrum. These were significantly greater than the values measured in the ilium and sacrum of LBP patients, （0.328±0.053）×10^-3 mm2/s in the ilium and （0.311±0.081）×10^-3 m2/s in the sacrum, and control group, （0.325±0.015）×10-3 mm2/s in the ilium and （0.318±0.011）×10^-3 mm2/s in the sacrum respectively. No statistically significant differences were found between LBP group and control group. The mean ADC value of focal DWI lesions in early AS patients was （0. 899±0.265）×10^-3 mm2/s, which was significantly higher than that of adjacent normal-appearance areas （（0.454±0.079）×10^-3 mm2/s）. WB-DWl detected abnormalities in the 15 additional AS patients both within the sacroiliac joints and at other sites mean ADC value of focal DWl lesions of this patient （1.220±0.299） ×10^-3 mm2/s in the ilium. corresponding to the clinical symptoms of the patients. The cohort was （1.286±0.311）×10^-3 mm2/s in the sacrum and Conclusions Subchondral marrow ADC values of subchondral marrows near the sacroiliac joints allow for the differentiation of patients with early AS from normal volunteers and LBP patients. Combined with post-processing techniques such as MIP and MPR, WB-DWl allows for the comprehensive assessment of AS patients, an evaluation potentially helpful in determining prognosis and following the therapeutic response.
