应用于非编网的SAN共享管理软件分析与评述

主要从非编网的共享存储网络结构、SANergy软件及其特点、ImageSAN软件及其特点、StorNext软件及其特点等方面,就应用于非编网的SAN共享管理软件的诸多问题进行一些分析与评述。

To explore the mechanism of Yigong San anti-gastric cancer and immune regulation

BACKGROUND Yigong San(YGS)is a representative prescription for the treatment of digestive disorders,which has been used in clinic for more than 1000 years.However,the mechanism of its anti-gastric cancer and regulate immunity are still remains unclear.AIM To explore the mechanism of YGS anti-gastric cancer and immune regulation.METHODS Firstly,collect the active ingredients and targets of YGS,and the differentially expressed genes of gastric cancer.Secondly,constructed a protein-protein interaction network between the targets of drugs and diseases,and screened hub genes.Then the clinical relevance,mutation and repair,tumor microenvironment and drug sensitivity of the hub gene were analyzed.Finally,molecular docking was used to verify the binding ability of YGS active ingredient and hub genes.RESULTS Firstly,obtained 55 common targets of gastric cancer and YGS.The Kyoto Encyclopedia of Genes and Genomes screened the microtubule-associated protein kinase signaling axis as the key pathway and IL6,EGFR,MMP2,MMP9 and TGFB1 as the hub genes.The 5 hub genes were involved in gastric carcinogenesis,staging,typing and prognosis,and their mutations promote gastric cancer progression.Finally,molecular docking results confirmed that the components of YGS can effectively bind to therapeutic targets.CONCLUSION YGS has the effect of anti-gastric cancer and immune regulation.

基于IP-SAN的电视节目非线性制作网络的设计与建设

本文介绍了扬州广播电视总台基于IP-SAN的电视节目非线性制作网络的设计与建设。重点介绍了网络组建方案对比与选型。提出了系统安全性方面的一些设计方案。对以后其他单位采用IP-SAN网络搭建中等规模的非线性制作网有一定的借鉴作用。

Therapeutic effect of San Bi Tang combined with glucosamine sulfate capsules in cold-dampness-type knee osteoarthritis

BACKGROUND Cold-dampness-type knee osteoarthritis is a common middle-aged and elderly disease,but its pathogenesis is not fully understood,and its clinical treatment has limitations.Glucosamine sulfate capsules are commonly used for treating arthritis,and San Bi Tang is a classic formula of traditional Chinese medicine(TCM)that has the effects of warming yang,dispelling dampness,relaxing muscles,and activating collaterals.This research hypothesized that the combination of modified San Bi Tang and glucosamine sulfate capsules could enhance the clinical efficacy of treating cold-dampness-type knee osteoarthritis through complementary effects.AIM To analyze the clinical efficacy of San Bi Tang combined with glucosamine sulfate capsules when treating cold-dampness-type knee osteoarthritis.METHODS A total of 110 patients with cold-dampness-type knee osteoarthritis were selected as research subjects and randomly divided into a control group and an experimental group of 55 cases each.The control group received only treatment with glucosamine sulfate capsules,while the experimental group received additional treatment with modified San Bi Tang for a duration of 5 wk.The patients’knee joint functions,liver and kidney function indicators,adverse reactions,and vital signs were evaluated and analyzed using SPSS 26.0 software.RESULTS Before treatment,the two groups’genders,ages,and scores were not significantly different,indicating comparability.Both groups’scores improved after treatment,which could indicate pain and knee joint function improvement,but the test group had better scores.The TCM-specific symptoms and the clinical efficacy of the treatment in the test group were higher.Before and after treatment,there were no abnormalities in the patients’liver and kidney function indicators.CONCLUSION The combination of modified San Bi Tang and glucosamine sulfate capsules is superior to treatment with sulfated glucosamine alone and has high safety.

Bioactive constituents and action mechanism of Xiaoyao San for treatment of non-alcoholic fatty liver disease

Xiaoyao San(XYS)is a classic Chinese medicine prescription.It is traditionally used to relieve syndrome of“liver stagnation and spleen deficiency”,a common syndrome type in traditional Chinese medicine,through soothing liver,tonifying spleen,and nourishing blood.Correspondingly,XYS has long application in the treatment of depression,dyspepsia and liver diseases.Given the rising of cutting-edge researches on XYS,there’s a significant need to diligently uncover the bioactive constituents and action mechanisms of XYS for treating non-alcoholic fatty liver disease accordingly.

Suppression of hepatic steatosis in non-alcoholic steatohepatitis model by modified Xiaoyao San formula:Evidence,mechanisms and perspective

In this letter,we comment on a recent publication by Mei et al,in the World Journal of Hepatology,investigating the hepatoprotective effects of the modified Xiaoyao San(MXS)formula in a male rat model of non-alcoholic steatohepatitis(NASH).The authors found that MXS treatment mitigated hepatic steatosis and inflam-mation in the NASH model,as evidenced by the reduction in lipid droplets(LDs),fibrosis markers and lipogenic factors.Interestingly,these hepatoprotective effects were associated with androgen upregulation(based on metabolomics analysis of male steroid hormone metabolites),adenosine 5’-monophosphate-activated protein kinase(AMPK)activation,and restoration of phosphatase and tensin homolog(PTEN)expression.However,the authors did not clearly discuss the relationships between MXS-induced hepatic steatosis reduction in the NASH model,and androgen upregulation,AMPK activation,and restoration of PTEN expression.This editorial emphasizes the reported mechanisms and explains how they act or interact with each other to reduce hepatic steatosis and inflammation in the NASH model.As a perspective,we propose additional mechanisms(such as autophagy/lipophagy activation in hepatocytes)for the clearance of LDs and suppression of hepatic steatosis by MXS in the NASH model.A proper understanding of the mechanisms of MXS-induced reduction of hepatic steatosis might help in the treatment of NASH and related diseases.

Decadal Forecasts of Large Earthquakes along the Northern San Andreas Fault System, California: Increased Activity on Regional Creeping Faults Prior to Major and Great Events

The three largest earthquakes in northern California since 1849 were preceded by increased decadal activity for moderate-size shocks along surrounding nearby faults. Increased seismicity, double-difference precise locations of earthquakes since 1968, geodetic data and fault offsets for the 1906 great shock are used to re-examine the timing and locations of possible future large earthquakes. The physical mechanisms of regional faults like the Calaveras, Hayward and Sargent, which exhibit creep, differ from those of the northern San Andreas, which is currently locked and is not creeping. Much decadal forerunning activity occurred on creeping faults. Moderate-size earthquakes along those faults became more frequent as stresses in the region increased in the latter part of the cycle of stress restoration for major and great earthquakes along the San Andreas. They may be useful for decadal forecasts. Yearly to decadal forecasts, however, are based on only a few major to great events. Activity along closer faults like that in the two years prior to the 1989 Loma Prieta shock needs to be examined for possible yearly forerunning changes to large plate boundary earthquakes. Geodetic observations are needed to focus on identifying creeping faults close to the San Andreas. The distribution of moderate-size earthquakes increased significantly since 1990 along the Hayward fault but not adjacent to the San Andreas fault to the south of San Francisco compared to what took place in the decades prior to the three major historic earthquakes in the region. It is now clear from a re-examination of the 1989 mainshock that the increased level of moderate-size shocks in the one to two preceding decades occurred on nearby East Bay faults. Double-difference locations of small earthquakes provide structural information about faults in the region, especially their depths. The northern San Andreas fault is divided into several strongly coupled segments based on differences in seismicity.

IP-SAN的研究与设计

FC-SAN存在着传播距离有限、成本高、管理困难等不足,IP-SAN的出现解决了FC-SAN的不足.通过对IP-SAN的体系结构和性能的研究,发现沿用FC-SAN体系结构的IP-SAN存在共享冲突、系统和数据不安全等问题.由于IP-SAN中的用户网与存域网在逻辑上属于不同的网络,但在物理上是同一网络.采用三方传送协议实现IP-SAN可以解决这些问题,实验表明这种方法是可行的.

SAN技术的探讨分析

存储区域网络(SAN)的被广泛接受,改变了原有的存储格局。本文对两种不同架构的SAN进行了介绍,分析了RAID这一存储的关键技术,研究了在实际应用中对不同RAID等级的选择原则,最后提出了制约发展的局限性,并介绍了业界最新的发展。

PB-g-SAN弹性体的合成及其对SAN树脂的增韧

采用种子乳液聚合技术在聚丁二烯(PB)乳胶粒子上接枝共聚苯乙烯(St)和丙烯腈(AN)合成了一系列PB质量分数为40%的PB g SAN弹性体·研究了共聚单体中叔 十二烷基硫醇(TDDM)质量分数对SAN共聚物接枝行为、弹性体粒子结构及其动态力学性能的影响·结果发现,随着单体中TDDM质量分数的增加,SAN在PB上的接枝率和接枝效率降低,弹性体粒子中SAN包容结构的尺寸增大,在低温区的动态剪切模量下降·将其与SAN树脂共混后发现在共聚单体中引入TDDM后提高了弹性体粒子的增韧效率·

融合多尺度通道注意力的开放词汇语义分割模型SAN

随着视觉语言模型的发展,开放词汇方法在识别带注释的标签空间之外的类别方面具有广泛应用。相比于弱监督和零样本方法,开放词汇方法被证明更加通用和有效。文章研究的目标是改进面向开放词汇分割的轻量化模型SAN,即引入基于多尺度通道注意力的特征融合机制AFF来改进该模型,并改进原始SAN结构中的双分支特征融合方法。然后在多个语义分割基准上评估了该改进算法,结果显示在几乎不改变参数量的情况下,模型表现有所提升。这一改进方案有助于简化未来开放词汇语义分割的研究。

SAN单元设备布置探讨

设备布置是化工工程设计的核心,也是开始详细工程设计的重要前提。设备布置既要做到安全、经济合理,也需满足工艺设计及操作、检维修和施工的要求。本文针对ABS装置中SAN单元部分展开设备布置讨论。

网络存储新技术IP-SAN在数字图书馆中的应用

FC-SAN存在着传播距离有限、成本高、管理困难等不足,IP-SAN的出现解决了FC-SAN的不足。本文介绍了基于iSCSI协议的SAN架构,讨论了FC-SAN和IP-SAN的区别,分析了IP-SAN在图书馆存储建设中的优势。

SAN存储在安防监控系统中的选择

现代安防监控系统主要是指数字高清监控系统,一般可以分解为三大部分:前端数字高清摄像机、存储设备、传输设备。现在前端摄像机越来越倾向高清化、IP化,而存储及传输设备以数字视频的压缩、传输、存储和播放为核心,实现分级存储、集中管理。本文就安防监控系统实际的应用中采用数据挖掘技术,对如何架设规模化的SAN(Storage Area Network)存储区域网络来保存庞大的录像资料进行选择并提出推荐意见。

IP-SAN网络存储技术在高校数字图书馆中的应用研究

数据的存储和管理是数字图书馆系统的核心,存储系统是数字图书馆基础设施的重要组成部分,以IP-SAN为基础构件的存储系统可以为图书管理信息化搭建坚实的硬件平台。在比较DAS、NAS、SAN三种存储技术的基础上,分析阐述了IP-SAN的优缺点,并结合山东建筑大学数字图书馆建设过程中网络存储技术的应用工程实例,提出了建立一个基于IP-SAN存储系统的高校数字图书馆建设的实施方案。

建立基于SAN技术的存储网络

各种网络应用服务的飞速发展,促进了以SAN(存储区域网)为代表的网络存储技术的发展。分析了SAN的部署架构及其技术特点,在此基础上讨论了在企业生产环境中如何将SAN存储技术与传统的NAS技术结合,构建可扩展的存储环境。

数字图书馆关于选择FCSAN与IPSAN的比较研究

全面比较分析了目前最流行的两种网络存储系统FC SAN与IP SAN,找出它们各自的优缺点,希望对各位同行将来选择存储系统时有所启迪。

PB-g-SAN弹性体对SAN树脂的增韧

采用种子乳液聚合法在聚丁二烯 (PB)乳胶粒上接枝共聚苯乙烯和丙烯腈 ,合成了PB含量为 40 %的PB g SAN共聚物粉料。将其与SAN树脂熔融共混制得了一系列不同组成的ABS树脂 ,研究了共混物的力学性能、加工性能和形态结构。结果表明 ,在SAN树脂中随着PB g SAN含量的增加 ,共混物的冲击韧性和断裂伸长率不断提高 ,而拉伸强度和熔融指数出现下降的趋势。形态结构研究结果表明 ,PB橡胶粒子均匀地分散在SAN基体中 ,其粒径约为 0 3μm ,在橡胶粒子中含有大量的包容结构 SAN次级粒子。

数字图书馆海量存储的理想选择——IP—SAN

分析了数字图书馆对海量存储的需求,总结了IP—SAN特点和优势。

SAN存储技术概述

随着Internet和网络技术的飞速发展,现代信息系统的数据呈爆炸式增长,数据的安全性和作业的连续性较之硬件设备本身更加重要,高速数据访问和平滑简单的扩容要求日益迫切。以前的存储技术只是将存储设备作为服务器的一个附属设备,服务器之间的大容量数据交换只能依赖传统的网络,在速度,安全性,跨平台共享,无限扩容等方面都无法适应IT技术发展的要求。SAN技术就是在这种情况下应运而生的。