Problems with clean water in coastal areas alongside an increase in population and community economic activities have diversified community activities.Coastal settlements bordering the high seas are characterized as a...Problems with clean water in coastal areas alongside an increase in population and community economic activities have diversified community activities.Coastal settlements bordering the high seas are characterized as arid areas with a lack of clean water.Here,the use of the range groundwater supply against seawater intrusion means that the water consumed by the community tastes salty and brackish.The availability of abundant seawater,processed through desalination technology,can be used to meet the daily clean water needs of coastal communities.Sustainable development goal(SDG)6 Water and Sanitation is concerned with ensuring that everyone has access to clean water and sanitation.In this regard,desalination technology is considered viable to achieve the SDGs in the environmental sector.Some countries have focused on using desalination technology to achieve target 6.4 by 2030.This goal aims to improve the efficiency of water use to reduce the number of people experiencing clean water scarcity by ensuring a sustainable supply of fresh water.The objective of this study is to examine the application of seawater desalination technology for clean water in the Kingdom of Saudi Arabia(KSA)and Indonesia,and identify the implications of desalination policies in these countries.Comparative studies were conducted using secondary data and literature studies on transforming seawater into clean water with technology.KSA applies seawater desalination technology to meet water needs.However,in Indonesia,policymaking has not holistically examined the potential of using seawater desalination technology for clean water.Until now,unlike in the KSA,Indonesia has not addressed the importance of the use of desalination technology in state policy.展开更多
This research focuses on the effects of migration on the TB infection rate and its prevention in Saudi Arabia, which has a large number of expatriates from TB-affected countries. Despite, based on the current global s...This research focuses on the effects of migration on the TB infection rate and its prevention in Saudi Arabia, which has a large number of expatriates from TB-affected countries. Despite, based on the current global statistics of TB occurrence, it is evident that the national incidence of TB has reduced from 10.55 per 100,000 in 2015 to 8.36 per 100,000 in 2019;despite this, there are still some difficulties because migrants bring new strains of Mycobacterium tuberculosis. Hindrances, including language barriers and perceived immigration status, hinder patients from seeking medical attention or doctors from diagnosing diseases. Each patient and each cultural group need special attention to public health, enhancing living circumstances, and health care support. Community participation, inclusion of TB control programs into functional healthcare facilities, and the functioning of TB programs need to be stressed to address TB issues. Considering the focus on social, economic, and cultural approaches, the country can make severe advancements in TB control and population protection. This holistic analysis is critical for a long-term effective strategy to combat TB in the Kingdom.展开更多
The World Health Organization declared COVID-19 a pandemic on March 11,2020 stating that it is a worldwide danger and requires imminent preventive strategies to minimise the loss of lives.COVID-19 has now affected mil...The World Health Organization declared COVID-19 a pandemic on March 11,2020 stating that it is a worldwide danger and requires imminent preventive strategies to minimise the loss of lives.COVID-19 has now affected millions across 211 countries in the world and the numbers continue to rise.The information discharged by the WHO till June 15,2020 reports 8,063,990 cases of COVID-19.As the world thinks about the lethal malady for which there is yet no immunization or a predefined course of drug,the nations are relentlessly working at the most ideal preventive systems to contain the infection.The Kingdom of Saudi Arabia(KSA)is additionally combating with the COVID-19 danger as the cases announced till June 15,2020 reached the count of 132,048 with 1,011 deaths.According to the report released by the KSA on June 14,2020,more than 4,000 cases of COVID-19 pandemic had been registered in the country.Tending to the impending requirement for successful preventive instruments to stem the fatalities caused by the disease,our examination expects to assess the severity of COVID-19 pandemic in cities of KSA.In addition,computational model for evaluating the severity of COVID-19 with the perspective of social influence factor is necessary for controlling the disease.Furthermore,a quantitative evaluation of severity associated with specific regions and cities of KSA would be a more effective reference for the healthcare sector in Saudi Arabia.Further,this paper has taken the Fuzzy Analytic Hierarchy Process(AHP)technique for quantitatively assessing the severity of COVID-19 pandemic in cities of KSA.The discoveries and the proposed structure would be a practical,expeditious and exceptionally precise evaluation system for assessing the severity of the pandemic in the cities of KSA.Hence these urban zones clearly emerge as the COVID-19 hotspots.The cities require suggestive measures of health organizations that must be introduced on a war footing basis to counter the pandemic.The analysis tabulated in our study will assist in mapping the rules and building a systematic structure that is immediate need in the cities with high severity levels due to the pandemic.展开更多
Antibiotic resistance is steadily increasing all over the world and has become a major public health challenge. To this end, colistin, an old bactericidal antibiotic of polymyxins family, has been recently re-introduc...Antibiotic resistance is steadily increasing all over the world and has become a major public health challenge. To this end, colistin, an old bactericidal antibiotic of polymyxins family, has been recently re-introduced as only available last-resort antibiotic arsenal for treatment of infections caused by multidrug resistant (MDR)-Gram-negative bacteria. However, the continual and extensive use of colistin has led to the emergence and rapid spreading of its bacterial resistance and non-susceptibility that is currently experiencing a critical healthcare issue with extensive global concern. Both transferable and intrinsic mechanisms of bacterial resistance to colistin have been documented in several countries and, therefore, comprehensive epidemiological data and reports are urgently needed to better understand the current status of this important antibiotic to properly optimize its clinical significance. In consistency, the present narrative review highlights both clinical use and reported bacterial resistance of colistin in the Kingdom of Saudi Arabia.展开更多
Many boundaries are hindering successful utilisation of e-health in the Kingdom of Saudi Arabia (KSA). We have previously proposed an integrated framework of knowledge management and knowledge discovery to overcome ba...Many boundaries are hindering successful utilisation of e-health in the Kingdom of Saudi Arabia (KSA). We have previously proposed an integrated framework of knowledge management and knowledge discovery to overcome barriers of e-health in KSA. Our proposed framework facilitates diabetes self-management for diabetic citizens in the Kingdom. In this paper, we will investigate and rank the barriers of e-health in KSA from the prospective of three stakeholders. We designed a questionnaire which constituted of items related to eight different e-health barriers and its associated sub-barriers. Citizens participated in 51 items related to six barriers. Healthcare professionals answered 83 items related to eight barriers. IT specialists participated in 74 items related to six barriers. Within each group of respondents, we compared the mean scores for each factor and sub-factor. The highest possible score for the mean was 5.00 and the lowest was 0.00 where the higher the mean score was the more the barrier constituted an obstacle for e-health in KSA. Citizens ranked the connectivity of information system as the top barrier with the mean of 4.0 whereas the least barrier was the cultural barriers with the mean score of 3.1. Healthcare professionals ranked the connectivity of information systems as the top barriers with the mean score of 3.5 whereas the least barrier was the technical expertise and computer skills with the mean score of 2.2. The top ranked barrier from the perspective of IT specialists was the medication safety with the mean score of 3.5 and the least ranked barrier was security and privacy with the mean score of 2.2. The results showed consistency with the literature review. Our proposed framework will contribute to the successful implementation of e-health initiatives and assist citizens in KSA to self- manage diabetes.展开更多
This is a study of university students’ awareness of diabetes mellitus, and the extent of their knowledge about it. The research is a quantitative design based on a survey of students (N = 700) at the University of T...This is a study of university students’ awareness of diabetes mellitus, and the extent of their knowledge about it. The research is a quantitative design based on a survey of students (N = 700) at the University of Tabuk in the Saudi province of Tabuk. The findings were that the students’ knowledge of diabetes indicators was encouraging, and that the faculty’s periodic diabetes awareness programs should be continued to ensure that new students can recognise diabetes characteristics. In assessing variables for knowledge of the disease in relation to the demographics of people on the Tabuk University campus, marital status and weight were significant indicators. The conclusion was that awareness programs should be continued to avoid complacency and to combat the disease.展开更多
Objectives: The aim of this study was to investigate the relationship between the levels of 25-hydroxyvitamin D and the adipokine resistin in Saudi diabetic patients and those at high risk to develop atherosclerotic c...Objectives: The aim of this study was to investigate the relationship between the levels of 25-hydroxyvitamin D and the adipokine resistin in Saudi diabetic patients and those at high risk to develop atherosclerotic cardiovascular diseases. Methodology: One hundred and sixty seven subjects were recruited for the cross-sectional study at King Fahad Medical City, Saudi Arabia. Blood samples were analyzed for biochemical parameters. Serum 25-hydroxyvitamin D and resistin levels were measured for all the participants. Result: Fifty six type-1, 55 type-2 diabetic patients and 56 healthy controls were recruited. Serum 25-hydroxyvitamin D level in the control group was 44.21 ± 41.80 μg/ml compared to 50.67 ± 35.60 μg/ml in the diabetic group (P = 0.427) with no significant different between type-2 diabetes mellitus and type-1 diabetes mellitus (P = 0.628). Resistin level in the control group was 14.00 ± 7.39μg/ml compared to 20.21 ± 16.94 μg/ml in the diabetic group (P ≤ 0.01), no significant difference between type-2 diabetes mellitus and type-1 diabetes mellitus (P = 0.817). Resistin in those taking vitamin D supplementation was 21.34 ± 18.27 μg/ml;and in those not taking vitamin D supplementation, it was 17.4 ± 11.19 μg/ml;(P = 0.237). There was significant negative correlation between 25-hydroxyvitamin D and resistin in type-2 diabetes mellitus (P ≤ 0.043) and no significant correlation was found between vitamin 25 (OH) D and resistin level in type-1 diabetes mellitus (P = 0.538). Blood urea and creatinine showed significant positive correlation with vitamin 25 (OH) D in one hand and resistin level on the other hand. Discussion and Conclusions: Several in vitro and in vivo studies have confirmed that the vitamin 25 (OH) D have numerous important functions in the body. The circulating vitamin 25 (OH) D and resistin levels were associated with general inflammation in renal diseases. This study showed significant negative correlation between resistin level and vitamin 25 (OH) D in type 2 diabetes mellitus reflecting their roles in glucose homeostasis. The positive correlation of resistin and vitamin D with urea may reflect their involvement in kidney dysfunction. The level of serum resistin showed slight increase in diabetic patients compared to control group and it was higher in type-2 diabetes mellitus. More efforts are needed to explore the physiological mechanism of vitamin 25 (OH) D and resistin action in metabolic disorders.展开更多
This study examines the trade-led growth(TLG)hypothesis for the Kingdom of Saudi Arabia.Using time-series annual data for the period 1985-2019,the ARDL approach and Toda-Yamamoto Granger causality test are applied to ...This study examines the trade-led growth(TLG)hypothesis for the Kingdom of Saudi Arabia.Using time-series annual data for the period 1985-2019,the ARDL approach and Toda-Yamamoto Granger causality test are applied to accomplish the study.The ARDL estimation reveals that trade openness positively causes economic growth in both the long and short run,and the TLG hypothesis is found valid for the Kingdom.The Toda-Yamamoto Granger causality test results have evidenced several unidirectional causalities.Of them,trade openness causes economic growth and supports the ARDL finding and hence the TLG hypothesis for the Kingdom.Moreover,trade openness causes gross fixed capital formation,and the labor force stimulates both economic growth and trade volume.The findings recommend that the Kingdom may increase its trade to reap further benefits and enhance its income growth.展开更多
Since December 2019,a new pandemic has appeared causing a considerable negative global impact.The SARS-CoV-2 first emerged from China and transformed to a global pandemic within a short time.The virus was further obse...Since December 2019,a new pandemic has appeared causing a considerable negative global impact.The SARS-CoV-2 first emerged from China and transformed to a global pandemic within a short time.The virus was further observed to be spreading rapidly and mutating at a fast pace,with over 5,775 distinct variations of the virus observed globally(at the time of submitting this paper).Extensive research has been ongoing worldwide in order to get a better understanding of its behaviour,influence and more importantly,ways for reducing its impact.Data analytics has been playing a pivotal role in this research to obtain valuable insights into understanding and fighting against the spread of infection.However,this is time and resource intensive,making it difficult to observe and quickly identify the impact of mutations.Factors such as the spread or virulence could explain the three months delay in revealing the new virus variant in the UK.This paper presents an extensive correlation analysis of the effect caused by the different SARS-CoV-2 strains,and their influence on the population across diverse factors,such as propagation and fatality rates,during the peak of the pandemic,with a focus on two major countries in the Middle East,the United Arab Emirate(UAE)and the Kingdom of Saudi Arabia(KSA).This research aims to investigate the epidemiological behaviour of the Coronavirus’genomic variants over time in the UAE,compared with the KSA,where correlation analysis is carried out for a number of cases,deaths and their statistical deviations.The results of the analysis highlight very interesting insights into the epidemiological impact of the Covid-19 genomic behaviour in both countries,which could lead to important actions taken to minimize the impact on wider public health,possibly saving lives,and the economy.For instance,our method identifies a potential correlation between a spike in the number of deaths per case of 5.5 observed in the UAE by March 24th,with the emergence of new genomic variants of the Coronavirus(G0_c,G0_e1 and G0_e2).Our proposed methodology can be instrumental in identifying and classifying new variations of the virus earlier,and possibly predicting foreseeable mutations through pattern analysis,hence creating proactive measures to control its spread,such as the recent case of the new virus variant,recently discovered in the UK.展开更多
Jazan area is located in the most active seismic zone region of the Kingdom of Saudi Arabia where there is a complicated geological structures and tectonics. This project reviews the seismic activities occurred in Jaz...Jazan area is located in the most active seismic zone region of the Kingdom of Saudi Arabia where there is a complicated geological structures and tectonics. This project reviews the seismic activities occurred in Jazan area together with reviewing the Saudi Building (Seismic) Code (SBC-301-2007) [1]. A multi-story reinforced concrete building, in Jazan city, was seismically analyzed using the Equivalent Lateral Force Procedure with the aid of STAAD PRO software. The building, which was Ordinary Reinforced Concrete Moment Resisting Frame (ORCMRF), was analyzed in compliance with the provisions of (SBC-301-2007) [1]. The most important parameters governing the analysis of this frame were dead load, live load and seismic loads. Seismic loads were computed as pairs of accelerations versus times. The damping ratio was taken as 0.05 (5% of the critical damping). The ground accelerations versus time periods were calculated using SBC-301-2007 together with parameters necessary to be used as input data for the program to calculate the seismic parameters, i.e., reactions, displacements, base shear, bending moments, shearing forces, drifts. The obtained results show effects of earthquake ground motions on building studied herein are so greater for the higher increases of the values of outputs resulting from seismic loads comparing to that due to static load only. Finally, the results obtained, clearly, show the importance of taking the Saudi seismic code provisions into account when analyzing and designing multi-story buildings in Jazan area.展开更多
Climate change is an emerging global problem.It has hazardous effects that vary across different geographic regions and populations.It is anticipated to have significant effects in Saudi Arabia.The present work review...Climate change is an emerging global problem.It has hazardous effects that vary across different geographic regions and populations.It is anticipated to have significant effects in Saudi Arabia.The present work reviews the future of human parasitoses in Saudi Arabia in response to the expected climate change.The key projections are increased precipitations,flash floods,unstable temperatures,sea-level rise and shoreline retreat.Such environmental changes could strongly influence the epidemiology of fly-borne,mosquito-borne,snail-borne and water-borne human parasitoses in the country.展开更多
The following paper explored data mining issues in Small and Medium Enterprises’ (SMEs), firstly exploring the relationship between data mining and economic development. With SME’s contributing most employment prosp...The following paper explored data mining issues in Small and Medium Enterprises’ (SMEs), firstly exploring the relationship between data mining and economic development. With SME’s contributing most employment prospects and output within any emerging economy such as the Kingdom of Saudi Arabia. Adopting technology will improve SME’s potential for effective decision making and efficient operations. Hence, it is important that SMEs have access to data mining techniques and implement the most suited into their business to improve their business intelligence (BI). The paper is aimed to critically review the existing literature on data mining in the field of SME to provide a theoretical underpinning for any future work. It has been found data mining to be complicated and fragmented with a multitude of options available for businesses from quite basic systems implemented within Excel or Access to more sophisticated cloud-based systems. For any business, data mining is trade-off between the need for data analysis, and intelligence against the cost and resource-use of the system put in place. Multiple challenges have been identified to data mining, most notably the resource-intensive nature of systems (both in terms of labor and capital) and the security issues of data collection, analysis and storage;with General Data Protection Regulation (GDPR) a key focus for Kingdom of Saudi Arabia businesses. With these challenges the paper suggests that any SME starts small with an internal data mining exercise to digitalize and analyze their customer data, scaling up over time as the business grows and acquires the resources needed to properly manage any system.展开更多
Abnormal levels of plasma lipid have been linked to atherosclerosis, strokes and heart conditions. Variations in high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels are considered as ri...Abnormal levels of plasma lipid have been linked to atherosclerosis, strokes and heart conditions. Variations in high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels are considered as risk factors for coronary artery disease (CAD). Furthermore, triglycerides are a leading cause of cardiovascular disease. Therefore, measurement of plasma lipid levels is an important mortality predictor. Several factors were associated with irregularity in plasma lipids such as genetic alterations. Recent researches have linked single nucleotides polymorphism (SNP) in ApoA5 gene with these deviations. In this study, we reported the effects of the genetic variant c.553G>T in ApoA5 on the levels of plasma lipids. To explore these effects, a case-control study including 280 male and female subjects (44 of them were assigned as CAD cases while the remaining subjects were categorized as control) was established. All patients in the study were recruited from the western region in KSA. The results have detected minor variations in LDL, HDL and cholesterol levels between CAD patients carrying T allele and CAD patients carrying the WT allele. However, there were no significant effects due to these variations. TG levels in the wild type carriers reached up to 291 mg/dl while T allele carriers, the cases, presented lower levels of TG (170 mg/dl and 71 mg/dl). Although, T allele showed no effects on plasma lipids with the exception of TG levels. We suggest by this study that T allele in this SNP might be considered as a valuable tool in the diagnosis of CAD.展开更多
文摘Problems with clean water in coastal areas alongside an increase in population and community economic activities have diversified community activities.Coastal settlements bordering the high seas are characterized as arid areas with a lack of clean water.Here,the use of the range groundwater supply against seawater intrusion means that the water consumed by the community tastes salty and brackish.The availability of abundant seawater,processed through desalination technology,can be used to meet the daily clean water needs of coastal communities.Sustainable development goal(SDG)6 Water and Sanitation is concerned with ensuring that everyone has access to clean water and sanitation.In this regard,desalination technology is considered viable to achieve the SDGs in the environmental sector.Some countries have focused on using desalination technology to achieve target 6.4 by 2030.This goal aims to improve the efficiency of water use to reduce the number of people experiencing clean water scarcity by ensuring a sustainable supply of fresh water.The objective of this study is to examine the application of seawater desalination technology for clean water in the Kingdom of Saudi Arabia(KSA)and Indonesia,and identify the implications of desalination policies in these countries.Comparative studies were conducted using secondary data and literature studies on transforming seawater into clean water with technology.KSA applies seawater desalination technology to meet water needs.However,in Indonesia,policymaking has not holistically examined the potential of using seawater desalination technology for clean water.Until now,unlike in the KSA,Indonesia has not addressed the importance of the use of desalination technology in state policy.
文摘This research focuses on the effects of migration on the TB infection rate and its prevention in Saudi Arabia, which has a large number of expatriates from TB-affected countries. Despite, based on the current global statistics of TB occurrence, it is evident that the national incidence of TB has reduced from 10.55 per 100,000 in 2015 to 8.36 per 100,000 in 2019;despite this, there are still some difficulties because migrants bring new strains of Mycobacterium tuberculosis. Hindrances, including language barriers and perceived immigration status, hinder patients from seeking medical attention or doctors from diagnosing diseases. Each patient and each cultural group need special attention to public health, enhancing living circumstances, and health care support. Community participation, inclusion of TB control programs into functional healthcare facilities, and the functioning of TB programs need to be stressed to address TB issues. Considering the focus on social, economic, and cultural approaches, the country can make severe advancements in TB control and population protection. This holistic analysis is critical for a long-term effective strategy to combat TB in the Kingdom.
基金Research and Development Grants Program for National Research Institutions and Centers(GRANTS),Target Research Program,Infections Diseases Research Grant Program,King Abdulaziz City for Science and Technology(KACST),Kingdom of Saudi Arabia,grant number(5-20-01-007-0028).
文摘The World Health Organization declared COVID-19 a pandemic on March 11,2020 stating that it is a worldwide danger and requires imminent preventive strategies to minimise the loss of lives.COVID-19 has now affected millions across 211 countries in the world and the numbers continue to rise.The information discharged by the WHO till June 15,2020 reports 8,063,990 cases of COVID-19.As the world thinks about the lethal malady for which there is yet no immunization or a predefined course of drug,the nations are relentlessly working at the most ideal preventive systems to contain the infection.The Kingdom of Saudi Arabia(KSA)is additionally combating with the COVID-19 danger as the cases announced till June 15,2020 reached the count of 132,048 with 1,011 deaths.According to the report released by the KSA on June 14,2020,more than 4,000 cases of COVID-19 pandemic had been registered in the country.Tending to the impending requirement for successful preventive instruments to stem the fatalities caused by the disease,our examination expects to assess the severity of COVID-19 pandemic in cities of KSA.In addition,computational model for evaluating the severity of COVID-19 with the perspective of social influence factor is necessary for controlling the disease.Furthermore,a quantitative evaluation of severity associated with specific regions and cities of KSA would be a more effective reference for the healthcare sector in Saudi Arabia.Further,this paper has taken the Fuzzy Analytic Hierarchy Process(AHP)technique for quantitatively assessing the severity of COVID-19 pandemic in cities of KSA.The discoveries and the proposed structure would be a practical,expeditious and exceptionally precise evaluation system for assessing the severity of the pandemic in the cities of KSA.Hence these urban zones clearly emerge as the COVID-19 hotspots.The cities require suggestive measures of health organizations that must be introduced on a war footing basis to counter the pandemic.The analysis tabulated in our study will assist in mapping the rules and building a systematic structure that is immediate need in the cities with high severity levels due to the pandemic.
文摘Antibiotic resistance is steadily increasing all over the world and has become a major public health challenge. To this end, colistin, an old bactericidal antibiotic of polymyxins family, has been recently re-introduced as only available last-resort antibiotic arsenal for treatment of infections caused by multidrug resistant (MDR)-Gram-negative bacteria. However, the continual and extensive use of colistin has led to the emergence and rapid spreading of its bacterial resistance and non-susceptibility that is currently experiencing a critical healthcare issue with extensive global concern. Both transferable and intrinsic mechanisms of bacterial resistance to colistin have been documented in several countries and, therefore, comprehensive epidemiological data and reports are urgently needed to better understand the current status of this important antibiotic to properly optimize its clinical significance. In consistency, the present narrative review highlights both clinical use and reported bacterial resistance of colistin in the Kingdom of Saudi Arabia.
文摘Many boundaries are hindering successful utilisation of e-health in the Kingdom of Saudi Arabia (KSA). We have previously proposed an integrated framework of knowledge management and knowledge discovery to overcome barriers of e-health in KSA. Our proposed framework facilitates diabetes self-management for diabetic citizens in the Kingdom. In this paper, we will investigate and rank the barriers of e-health in KSA from the prospective of three stakeholders. We designed a questionnaire which constituted of items related to eight different e-health barriers and its associated sub-barriers. Citizens participated in 51 items related to six barriers. Healthcare professionals answered 83 items related to eight barriers. IT specialists participated in 74 items related to six barriers. Within each group of respondents, we compared the mean scores for each factor and sub-factor. The highest possible score for the mean was 5.00 and the lowest was 0.00 where the higher the mean score was the more the barrier constituted an obstacle for e-health in KSA. Citizens ranked the connectivity of information system as the top barrier with the mean of 4.0 whereas the least barrier was the cultural barriers with the mean score of 3.1. Healthcare professionals ranked the connectivity of information systems as the top barriers with the mean score of 3.5 whereas the least barrier was the technical expertise and computer skills with the mean score of 2.2. The top ranked barrier from the perspective of IT specialists was the medication safety with the mean score of 3.5 and the least ranked barrier was security and privacy with the mean score of 2.2. The results showed consistency with the literature review. Our proposed framework will contribute to the successful implementation of e-health initiatives and assist citizens in KSA to self- manage diabetes.
文摘This is a study of university students’ awareness of diabetes mellitus, and the extent of their knowledge about it. The research is a quantitative design based on a survey of students (N = 700) at the University of Tabuk in the Saudi province of Tabuk. The findings were that the students’ knowledge of diabetes indicators was encouraging, and that the faculty’s periodic diabetes awareness programs should be continued to ensure that new students can recognise diabetes characteristics. In assessing variables for knowledge of the disease in relation to the demographics of people on the Tabuk University campus, marital status and weight were significant indicators. The conclusion was that awareness programs should be continued to avoid complacency and to combat the disease.
文摘Objectives: The aim of this study was to investigate the relationship between the levels of 25-hydroxyvitamin D and the adipokine resistin in Saudi diabetic patients and those at high risk to develop atherosclerotic cardiovascular diseases. Methodology: One hundred and sixty seven subjects were recruited for the cross-sectional study at King Fahad Medical City, Saudi Arabia. Blood samples were analyzed for biochemical parameters. Serum 25-hydroxyvitamin D and resistin levels were measured for all the participants. Result: Fifty six type-1, 55 type-2 diabetic patients and 56 healthy controls were recruited. Serum 25-hydroxyvitamin D level in the control group was 44.21 ± 41.80 μg/ml compared to 50.67 ± 35.60 μg/ml in the diabetic group (P = 0.427) with no significant different between type-2 diabetes mellitus and type-1 diabetes mellitus (P = 0.628). Resistin level in the control group was 14.00 ± 7.39μg/ml compared to 20.21 ± 16.94 μg/ml in the diabetic group (P ≤ 0.01), no significant difference between type-2 diabetes mellitus and type-1 diabetes mellitus (P = 0.817). Resistin in those taking vitamin D supplementation was 21.34 ± 18.27 μg/ml;and in those not taking vitamin D supplementation, it was 17.4 ± 11.19 μg/ml;(P = 0.237). There was significant negative correlation between 25-hydroxyvitamin D and resistin in type-2 diabetes mellitus (P ≤ 0.043) and no significant correlation was found between vitamin 25 (OH) D and resistin level in type-1 diabetes mellitus (P = 0.538). Blood urea and creatinine showed significant positive correlation with vitamin 25 (OH) D in one hand and resistin level on the other hand. Discussion and Conclusions: Several in vitro and in vivo studies have confirmed that the vitamin 25 (OH) D have numerous important functions in the body. The circulating vitamin 25 (OH) D and resistin levels were associated with general inflammation in renal diseases. This study showed significant negative correlation between resistin level and vitamin 25 (OH) D in type 2 diabetes mellitus reflecting their roles in glucose homeostasis. The positive correlation of resistin and vitamin D with urea may reflect their involvement in kidney dysfunction. The level of serum resistin showed slight increase in diabetic patients compared to control group and it was higher in type-2 diabetes mellitus. More efforts are needed to explore the physiological mechanism of vitamin 25 (OH) D and resistin action in metabolic disorders.
文摘This study examines the trade-led growth(TLG)hypothesis for the Kingdom of Saudi Arabia.Using time-series annual data for the period 1985-2019,the ARDL approach and Toda-Yamamoto Granger causality test are applied to accomplish the study.The ARDL estimation reveals that trade openness positively causes economic growth in both the long and short run,and the TLG hypothesis is found valid for the Kingdom.The Toda-Yamamoto Granger causality test results have evidenced several unidirectional causalities.Of them,trade openness causes economic growth and supports the ARDL finding and hence the TLG hypothesis for the Kingdom.Moreover,trade openness causes gross fixed capital formation,and the labor force stimulates both economic growth and trade volume.The findings recommend that the Kingdom may increase its trade to reap further benefits and enhance its income growth.
基金This work is funded by RIF project,from Zayed University,the UAE.AB www.zu.ac.ae.
文摘Since December 2019,a new pandemic has appeared causing a considerable negative global impact.The SARS-CoV-2 first emerged from China and transformed to a global pandemic within a short time.The virus was further observed to be spreading rapidly and mutating at a fast pace,with over 5,775 distinct variations of the virus observed globally(at the time of submitting this paper).Extensive research has been ongoing worldwide in order to get a better understanding of its behaviour,influence and more importantly,ways for reducing its impact.Data analytics has been playing a pivotal role in this research to obtain valuable insights into understanding and fighting against the spread of infection.However,this is time and resource intensive,making it difficult to observe and quickly identify the impact of mutations.Factors such as the spread or virulence could explain the three months delay in revealing the new virus variant in the UK.This paper presents an extensive correlation analysis of the effect caused by the different SARS-CoV-2 strains,and their influence on the population across diverse factors,such as propagation and fatality rates,during the peak of the pandemic,with a focus on two major countries in the Middle East,the United Arab Emirate(UAE)and the Kingdom of Saudi Arabia(KSA).This research aims to investigate the epidemiological behaviour of the Coronavirus’genomic variants over time in the UAE,compared with the KSA,where correlation analysis is carried out for a number of cases,deaths and their statistical deviations.The results of the analysis highlight very interesting insights into the epidemiological impact of the Covid-19 genomic behaviour in both countries,which could lead to important actions taken to minimize the impact on wider public health,possibly saving lives,and the economy.For instance,our method identifies a potential correlation between a spike in the number of deaths per case of 5.5 observed in the UAE by March 24th,with the emergence of new genomic variants of the Coronavirus(G0_c,G0_e1 and G0_e2).Our proposed methodology can be instrumental in identifying and classifying new variations of the virus earlier,and possibly predicting foreseeable mutations through pattern analysis,hence creating proactive measures to control its spread,such as the recent case of the new virus variant,recently discovered in the UK.
文摘Jazan area is located in the most active seismic zone region of the Kingdom of Saudi Arabia where there is a complicated geological structures and tectonics. This project reviews the seismic activities occurred in Jazan area together with reviewing the Saudi Building (Seismic) Code (SBC-301-2007) [1]. A multi-story reinforced concrete building, in Jazan city, was seismically analyzed using the Equivalent Lateral Force Procedure with the aid of STAAD PRO software. The building, which was Ordinary Reinforced Concrete Moment Resisting Frame (ORCMRF), was analyzed in compliance with the provisions of (SBC-301-2007) [1]. The most important parameters governing the analysis of this frame were dead load, live load and seismic loads. Seismic loads were computed as pairs of accelerations versus times. The damping ratio was taken as 0.05 (5% of the critical damping). The ground accelerations versus time periods were calculated using SBC-301-2007 together with parameters necessary to be used as input data for the program to calculate the seismic parameters, i.e., reactions, displacements, base shear, bending moments, shearing forces, drifts. The obtained results show effects of earthquake ground motions on building studied herein are so greater for the higher increases of the values of outputs resulting from seismic loads comparing to that due to static load only. Finally, the results obtained, clearly, show the importance of taking the Saudi seismic code provisions into account when analyzing and designing multi-story buildings in Jazan area.
文摘Climate change is an emerging global problem.It has hazardous effects that vary across different geographic regions and populations.It is anticipated to have significant effects in Saudi Arabia.The present work reviews the future of human parasitoses in Saudi Arabia in response to the expected climate change.The key projections are increased precipitations,flash floods,unstable temperatures,sea-level rise and shoreline retreat.Such environmental changes could strongly influence the epidemiology of fly-borne,mosquito-borne,snail-borne and water-borne human parasitoses in the country.
文摘The following paper explored data mining issues in Small and Medium Enterprises’ (SMEs), firstly exploring the relationship between data mining and economic development. With SME’s contributing most employment prospects and output within any emerging economy such as the Kingdom of Saudi Arabia. Adopting technology will improve SME’s potential for effective decision making and efficient operations. Hence, it is important that SMEs have access to data mining techniques and implement the most suited into their business to improve their business intelligence (BI). The paper is aimed to critically review the existing literature on data mining in the field of SME to provide a theoretical underpinning for any future work. It has been found data mining to be complicated and fragmented with a multitude of options available for businesses from quite basic systems implemented within Excel or Access to more sophisticated cloud-based systems. For any business, data mining is trade-off between the need for data analysis, and intelligence against the cost and resource-use of the system put in place. Multiple challenges have been identified to data mining, most notably the resource-intensive nature of systems (both in terms of labor and capital) and the security issues of data collection, analysis and storage;with General Data Protection Regulation (GDPR) a key focus for Kingdom of Saudi Arabia businesses. With these challenges the paper suggests that any SME starts small with an internal data mining exercise to digitalize and analyze their customer data, scaling up over time as the business grows and acquires the resources needed to properly manage any system.
文摘Abnormal levels of plasma lipid have been linked to atherosclerosis, strokes and heart conditions. Variations in high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels are considered as risk factors for coronary artery disease (CAD). Furthermore, triglycerides are a leading cause of cardiovascular disease. Therefore, measurement of plasma lipid levels is an important mortality predictor. Several factors were associated with irregularity in plasma lipids such as genetic alterations. Recent researches have linked single nucleotides polymorphism (SNP) in ApoA5 gene with these deviations. In this study, we reported the effects of the genetic variant c.553G>T in ApoA5 on the levels of plasma lipids. To explore these effects, a case-control study including 280 male and female subjects (44 of them were assigned as CAD cases while the remaining subjects were categorized as control) was established. All patients in the study were recruited from the western region in KSA. The results have detected minor variations in LDL, HDL and cholesterol levels between CAD patients carrying T allele and CAD patients carrying the WT allele. However, there were no significant effects due to these variations. TG levels in the wild type carriers reached up to 291 mg/dl while T allele carriers, the cases, presented lower levels of TG (170 mg/dl and 71 mg/dl). Although, T allele showed no effects on plasma lipids with the exception of TG levels. We suggest by this study that T allele in this SNP might be considered as a valuable tool in the diagnosis of CAD.