BACKGROUND The efficacy of cognitive behavioral group therapy(CBGT)for cognitive dysfunction and negative symptoms of schizophrenia is established,but more evidence is required.AIM To assess the effectiveness of CBGT ...BACKGROUND The efficacy of cognitive behavioral group therapy(CBGT)for cognitive dysfunction and negative symptoms of schizophrenia is established,but more evidence is required.AIM To assess the effectiveness of CBGT combined with mental health education as a treatment for schizophrenia compared with mental health education alone.METHODS In all,120 schizophrenia out-patients were randomized into CBGT combined with mental health education or single mental health education.The primary outcomes were positive and negative symptoms,cognitive function,excitatory factor,anxiety and depression symptom improvements on the positive and negative syndrome scale score.Secondary outcome measures included social function and drug compliance.RESULTS There were significant differences between CBGT combined with mental health education and single mental health education on measures of positive and negative symptoms,cognitive functions,excitatory factor,anxiety and depression symptoms,and social functions.No other significant difference in outcomes was observed.CONCLUSION CBGT combined with mental health education may be relevant beneficial treatment method in reducing symptoms,cognitive and social functions of patients with schizophrenia.展开更多
AIM To review available evidence on the use of cognitive behavioural therapy(CBT) for treating obsessive compulsive disorder co-occurring with psychosis.METHODS In this paper we present a detailed and comprehensive re...AIM To review available evidence on the use of cognitive behavioural therapy(CBT) for treating obsessive compulsive disorder co-occurring with psychosis.METHODS In this paper we present a detailed and comprehensive review of the current literature focusing on CBT treatment of obsessive compulsive disorder(OCD) co-occurring with schizophrenia or schizoaffective disorder. We identified relevant literature published between 2001 and May 2016 through MEDLINE/PubM ed search using as search string("obsessive compulsive disorders" or "obsessive compulsive symptoms") and("schizophrenia" or "schizoaffective disorder" or "psychosis") and("cognitive behavioural therapy"). Other citations of interest were further identified from references reported in the accessed articles. The search was limited to studies written in English and carried out in adult patients. A total of 9 studies, 8 case reports and 1 case series, were found.RESULTS The reviewed evidence indicates that CBT is:(1) safe, i.e., does not worsen psychotic symptoms;(2) well accepted, with a discontinuation rate quite similar to that reported for patients with OCD without psychosis comorbidity;(3) effective, with a symptom reduction quite similar to that reported for patients with OCD without psychosis and for SRIs treatment of OCD cooccurring with psychosis; and(4) effective in patients with OCD induced by second-generation antipsychotic as well as in patients with OCD not induced by secondgeneration antipsychotic. Alcohol/substance use disorder comorbidity and OCD onset preceding that of SCH/SA was predictors of poor outcome. These results are derived only by additional studies with adequate sample size.CONCLUSION Our results support the use of CBT for OCD in patients with psychosis.展开更多
The manuscript correspond to an editorial in order to assess the most important and effective interventions for people with psychosis in the early stages.
目的探讨认知行为干预对抑郁症患者抑郁情绪和自杀态度的影响。方法选择2005年9月1日—2006年5月31日入院的抑郁症患者,共80例,随机分为两组。对照组采用精神科护理常规、支持性心理护理,干预组在此基础上实施针对性的认知行为干预。运...目的探讨认知行为干预对抑郁症患者抑郁情绪和自杀态度的影响。方法选择2005年9月1日—2006年5月31日入院的抑郁症患者,共80例,随机分为两组。对照组采用精神科护理常规、支持性心理护理,干预组在此基础上实施针对性的认知行为干预。运用汉密顿抑郁量表(Hamilton depression rating scale for depression,HAMD)和自杀态度问卷(Questionnaire of suicide attitude,QSA)对干预效果进行评定。结果入院第3周末及第6周末干预组HAMD量表分值显著低于对照组,干预组HAMD的总平均减分值显著大于对照组的总平均减分值,入院第6周末干预组对自杀行为性质的认识和对自杀者、自杀者家属及安乐死的态度分值显著高于对照组。结论认知行为干预对改善抑郁症患者的抑郁情绪和自杀态度有着明显的影响。展开更多
基金Supported by Science and Technology Innovation Bureau,Longhua District,Shenzhen,Guangdong Province,China,No.2020202.
文摘BACKGROUND The efficacy of cognitive behavioral group therapy(CBGT)for cognitive dysfunction and negative symptoms of schizophrenia is established,but more evidence is required.AIM To assess the effectiveness of CBGT combined with mental health education as a treatment for schizophrenia compared with mental health education alone.METHODS In all,120 schizophrenia out-patients were randomized into CBGT combined with mental health education or single mental health education.The primary outcomes were positive and negative symptoms,cognitive function,excitatory factor,anxiety and depression symptom improvements on the positive and negative syndrome scale score.Secondary outcome measures included social function and drug compliance.RESULTS There were significant differences between CBGT combined with mental health education and single mental health education on measures of positive and negative symptoms,cognitive functions,excitatory factor,anxiety and depression symptoms,and social functions.No other significant difference in outcomes was observed.CONCLUSION CBGT combined with mental health education may be relevant beneficial treatment method in reducing symptoms,cognitive and social functions of patients with schizophrenia.
基金Supported by "Fondazione dell’Istituto di Psicopatologia Onlus",Rome,Italy
文摘AIM To review available evidence on the use of cognitive behavioural therapy(CBT) for treating obsessive compulsive disorder co-occurring with psychosis.METHODS In this paper we present a detailed and comprehensive review of the current literature focusing on CBT treatment of obsessive compulsive disorder(OCD) co-occurring with schizophrenia or schizoaffective disorder. We identified relevant literature published between 2001 and May 2016 through MEDLINE/PubM ed search using as search string("obsessive compulsive disorders" or "obsessive compulsive symptoms") and("schizophrenia" or "schizoaffective disorder" or "psychosis") and("cognitive behavioural therapy"). Other citations of interest were further identified from references reported in the accessed articles. The search was limited to studies written in English and carried out in adult patients. A total of 9 studies, 8 case reports and 1 case series, were found.RESULTS The reviewed evidence indicates that CBT is:(1) safe, i.e., does not worsen psychotic symptoms;(2) well accepted, with a discontinuation rate quite similar to that reported for patients with OCD without psychosis comorbidity;(3) effective, with a symptom reduction quite similar to that reported for patients with OCD without psychosis and for SRIs treatment of OCD cooccurring with psychosis; and(4) effective in patients with OCD induced by second-generation antipsychotic as well as in patients with OCD not induced by secondgeneration antipsychotic. Alcohol/substance use disorder comorbidity and OCD onset preceding that of SCH/SA was predictors of poor outcome. These results are derived only by additional studies with adequate sample size.CONCLUSION Our results support the use of CBT for OCD in patients with psychosis.
基金The PI014/0044,of the Plan Nacional de I+D+I and co-funded by ISCⅢ–Subdirección General de Evaluación y Formento de la Investigación Sanitariaand Fondo Europeo de Desarrollo Regional(FEDER)
文摘The manuscript correspond to an editorial in order to assess the most important and effective interventions for people with psychosis in the early stages.
文摘目的探讨认知行为干预对抑郁症患者抑郁情绪和自杀态度的影响。方法选择2005年9月1日—2006年5月31日入院的抑郁症患者,共80例,随机分为两组。对照组采用精神科护理常规、支持性心理护理,干预组在此基础上实施针对性的认知行为干预。运用汉密顿抑郁量表(Hamilton depression rating scale for depression,HAMD)和自杀态度问卷(Questionnaire of suicide attitude,QSA)对干预效果进行评定。结果入院第3周末及第6周末干预组HAMD量表分值显著低于对照组,干预组HAMD的总平均减分值显著大于对照组的总平均减分值,入院第6周末干预组对自杀行为性质的认识和对自杀者、自杀者家属及安乐死的态度分值显著高于对照组。结论认知行为干预对改善抑郁症患者的抑郁情绪和自杀态度有着明显的影响。
