Scleromyxedema is a rare dermatologic disorder,characterized by erythematous or yellowish lichenoid waxy papules.Neurological manifestations are rare but well-recognized.A 51-year-old woman,diagnosed with scleromyxede...Scleromyxedema is a rare dermatologic disorder,characterized by erythematous or yellowish lichenoid waxy papules.Neurological manifestations are rare but well-recognized.A 51-year-old woman,diagnosed with scleromyxedema,was admitted to the hospital with status epilepticus,caused by brain lesions,as disclosed in a brain magnetic resonance imaging(MRI).The patient was treated with anticonvulsants and corticosteroids and gradually recovered fully.A complete remission of the lesions was shown in a follow-up brain MRI.In cases with scleromyxedema and the presence of neurological manifestations,we need to pay attention to central nervous system involvement,especially when combined with brain MRI lesions,and treat the patient appropriately.展开更多
To analyze the clinical symptoms and signs in cases of oral submucous fibrosis which has transformed into squamous cell carcinoma, twenty-nine patients with squamous cell carcinoma correlated with oral submucous fibro...To analyze the clinical symptoms and signs in cases of oral submucous fibrosis which has transformed into squamous cell carcinoma, twenty-nine patients with squamous cell carcinoma correlated with oral submucous fibrosis, leukoplakia, lichen planus were taken biopsy for positive diagnosis. The clinical and pathological diagnosis of oral submucous fibrosis depended on clinical and pathological diagnostic standards. The oral submucous fibrosis involving different portions and size in the mouth was observed and recorded. The portions of oral cancer, clinical findings and symptoms, cancerous size, the conditions of the local lymphatic nodes and of oral submucous fibrosis correlated with squamous cell carcinoma in the mouth, oral leukoplakia, lichen planus were also observed and recorded. In twenty-nine patients with oral squamous cell carcinoma, duration from oral submucous fibrosis transformed into oral cancer ranged from 2 to 15 years with an average year of 6.69. The serious degrees of oral submucous fibrosis in the patients with oral cancer were that the moderately advanced stage was found in 3 cases (10.34%) and the advanced stage was found in 26 cases (89.65%). The cancerous portion was that the buccal mucosa was found in 9 cases (31.03%);the tongue was found in 14 cases (48.27%);the other portion was found in the rest 6 cases (20.68%). Among the twenty-nine patients twenty-three patients with squamous cell carcinoma were associated with leukoplakia (79.31%), five patients were associated with lichen planus (17.24%). Twenty-seven patients (93.1%) had habits of betel quid chewing, smoked cigarette and drank alcohol, the rest two patients had habits of betel quid chewing and cigarette smoking. The present study demonstrates that oral submucous fibrosis is a real precancerous lesion and may transform into squamous cell carcinoma in the mouth.展开更多
文摘Scleromyxedema is a rare dermatologic disorder,characterized by erythematous or yellowish lichenoid waxy papules.Neurological manifestations are rare but well-recognized.A 51-year-old woman,diagnosed with scleromyxedema,was admitted to the hospital with status epilepticus,caused by brain lesions,as disclosed in a brain magnetic resonance imaging(MRI).The patient was treated with anticonvulsants and corticosteroids and gradually recovered fully.A complete remission of the lesions was shown in a follow-up brain MRI.In cases with scleromyxedema and the presence of neurological manifestations,we need to pay attention to central nervous system involvement,especially when combined with brain MRI lesions,and treat the patient appropriately.
文摘To analyze the clinical symptoms and signs in cases of oral submucous fibrosis which has transformed into squamous cell carcinoma, twenty-nine patients with squamous cell carcinoma correlated with oral submucous fibrosis, leukoplakia, lichen planus were taken biopsy for positive diagnosis. The clinical and pathological diagnosis of oral submucous fibrosis depended on clinical and pathological diagnostic standards. The oral submucous fibrosis involving different portions and size in the mouth was observed and recorded. The portions of oral cancer, clinical findings and symptoms, cancerous size, the conditions of the local lymphatic nodes and of oral submucous fibrosis correlated with squamous cell carcinoma in the mouth, oral leukoplakia, lichen planus were also observed and recorded. In twenty-nine patients with oral squamous cell carcinoma, duration from oral submucous fibrosis transformed into oral cancer ranged from 2 to 15 years with an average year of 6.69. The serious degrees of oral submucous fibrosis in the patients with oral cancer were that the moderately advanced stage was found in 3 cases (10.34%) and the advanced stage was found in 26 cases (89.65%). The cancerous portion was that the buccal mucosa was found in 9 cases (31.03%);the tongue was found in 14 cases (48.27%);the other portion was found in the rest 6 cases (20.68%). Among the twenty-nine patients twenty-three patients with squamous cell carcinoma were associated with leukoplakia (79.31%), five patients were associated with lichen planus (17.24%). Twenty-seven patients (93.1%) had habits of betel quid chewing, smoked cigarette and drank alcohol, the rest two patients had habits of betel quid chewing and cigarette smoking. The present study demonstrates that oral submucous fibrosis is a real precancerous lesion and may transform into squamous cell carcinoma in the mouth.
