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ICU-acquired weakness in critically ill patients at risk of malnutrition: risk factors, biomarkers, and early enteral nutrition impact
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作者 Qingliu Zheng Changyun Liu +4 位作者 Lingying Le Qiqi Wu Zhihong Xu Jiyan Lin Qiuyun Chen 《World Journal of Emergency Medicine》 2025年第1期51-56,共6页
BACKGROUND: This study aimed to explore the risk factors associated with intensive care unitacquired weakness(ICU-AW) in critically ill patients at risk of malnutrition and to evaluate the efficacy of early enteral nu... BACKGROUND: This study aimed to explore the risk factors associated with intensive care unitacquired weakness(ICU-AW) in critically ill patients at risk of malnutrition and to evaluate the efficacy of early enteral nutrition(EEN) and the role of biomarkers in managing ICU-AW.METHODS: This retrospective, observational cohort study included 180 patients at risk of malnutrition admitted to the emergency intensive care unit of the First Affiliated Hospital of Xiamen University Hospital from January 2022 to December 2023. Patients were divided into ICU-AW group and non-ICU-AW group according to whether they developed ICU-AW, or categorized into EEN and parenteral nutrition(PN) groups according to nutritional support. ICU-AW was diagnosed using the Medical Research Council score. The primary outcome was the occurrence of ICU-AW.RESULTS: The significant factors associated with ICU-AW included age, sex, type of nutritional therapy, mechanical ventilation(MV), body mass index(BMI), blood urea nitrogen(BUN), and creatinine(Cr) levels(P<0.05). The PN group developed ICU-AW earlier than did the EEN group, with a significant difference observed(log-rank P<0.001). Among biomarkers for ICU-AW, the mean prealbumin(PAB)/C-reactive protein(CRP) ratio had the highest diagnostic accuracy(area under the curve [AUC] 0.928, 95% confidence interval [95% CI] 0.892–0.946), surpassing the mean Cr/BUN ratio(AUC 0.740, 95% CI 0.663–0.819) and mean transferrin levels(AUC 0.653, 95% CI 0.574–0.733).CONCLUSION: Independent risk factors for ICU-AW include female sex, advanced age, PN, MV, lower BMI, and elevated BUN and Cr levels. EEN may potentially delay ICU-AW onset, and the PAB/CRP ratio may be an effective diagnostic marker for this condition. 展开更多
关键词 Intensive care units Muscular weakness Hospital-acquired condition Enteral nutrition Biomarkers Risk factors
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Agricultural production structure,market conditions and farmers’nutritional intake in rural China 被引量:1
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作者 WAN Yue HU Hao Wuyang HU 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2022年第6期1812-1824,共13页
Nutrition poverty alleviation is an effective measure to improve the nutritional status of economically disadvantaged individuals,fundamentally improving their health and reducing poverty.Based on the Entitlement Theo... Nutrition poverty alleviation is an effective measure to improve the nutritional status of economically disadvantaged individuals,fundamentally improving their health and reducing poverty.Based on the Entitlement Theory and using the China Health and Nutrition Survey(CHNS)data,this paper examines the relationship between farmers’nutritional intake,production structure and regional market conditions.Results show that farmers with diversified production have better nutritional intake than those who specialize.Furthermore,the correlation between regional market conditions and nutritional intake varies between economically disadvantaged and non-economically disadvantaged households.Market conditions significantly influence the carbohydrate and fat intake of economically disadvantaged households and are positively associated with the dietary structure and nutritional intake of non-economically disadvantaged ones.Moreover,income is positively correlated with the nutritional intake of non-economically disadvantaged households but not with economically disadvantaged ones. 展开更多
关键词 Chinese farmer nutrition economically disadvantaged households diversity of agricultural production regional market conditions
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Nutritional Conditions for Application of Bacillus in Intensive Aquaculture of Shrimp 被引量:1
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作者 傅冠学 阮波 +2 位作者 朱晶婷 冯双双 高阳 《Agricultural Science & Technology》 CAS 2017年第6期1029-1032,共4页
With the rapid development of intensive shrimp aquaculture, breeding en- vironment has been damaged severely, and diseases occur frequently. In aquacul- ture, probiotics are generally used to improve the ecological en... With the rapid development of intensive shrimp aquaculture, breeding en- vironment has been damaged severely, and diseases occur frequently. In aquacul- ture, probiotics are generally used to improve the ecological environment and inhibit pathogenic microorganisms, thereby reducing the incidence of diseases.They have been more and more commonly used in the intensive aquaculture of shrimp, and require certain nutritional conditions and need to reach a certain number to produce a good performance. In this paper, the basic nutrition requirements of the common- ly-used probiotic Bacillus and its water quality-improving effect were investigated to provide theoretical guidance for production. 展开更多
关键词 Aquaculture environment BACILLUS nutrition conditions Carbon nitrogen ratio
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Optimization of Screening Method for Feed Nutrition and Processing Conditions
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作者 YangYun-qing WangYi-tong 《Journal of Northeast Agricultural University(English Edition)》 CAS 1999年第2期112-116,共5页
On the basis of regressional relationship between nutritional indexes and technological conditions,when confronted with feed quality that contains multiple nutritional indexes,a comprehensive equation of evaluating fe... On the basis of regressional relationship between nutritional indexes and technological conditions,when confronted with feed quality that contains multiple nutritional indexes,a comprehensive equation of evaluating feed quality was developed by using fuzzy mathematical method at first in this study,and then the optimum technological conditions were established by introduction of statistical frequency analysis method pursuant to the comprehensive evaluating equation mentioned above compared with conventional multi-aim nonlinear programming,this method can lead to easy solutions,and also can make adjustment of the importance of nutritional indexes to feed quality according to practical considerations.An example was given of soybean extruding to show how the method worked. 展开更多
关键词 feed processing nutritional index technological condition OPTIMIZATION
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Rice Germination and Its Impact on Technological and Nutritional Properties:A Review 被引量:3
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作者 LucasÁvila do NASCIMENTO Abhilasha ABHILASHA +2 位作者 Jaspreet SINGH Moacir Cardoso ELIAS Rosana COLUSSI 《Rice science》 SCIE CSCD 2022年第3期201-215,共15页
Grain germination is a process involving numerous factors that influence the biochemical processes inside the plant cells.This review covered the abiotic factors that lead to the germination and significantly impact t... Grain germination is a process involving numerous factors that influence the biochemical processes inside the plant cells.This review covered the abiotic factors that lead to the germination and significantly impact the nutritional properties and digestion behavior of rice grains.The macro-and micro-nutrients can be changed depending on the intensity of the applied variables during germination.For instance,germination time can increase the protein content in the grain and concurrently reduce its protein digestibility.In most cases,the number of bioactive compounds present in rice grains are increased regardless of germination conditions.Germination can promote the complexation of nutrients and thus negatively interfere with the digestibility of macronutrients.This review highlighted the influence of the germination process on the nutritional quality of rice grains,providing information about the germination conditions and their impacts on the anabolic and catabolic reactions of the grain,emphasizing the health benefits. 展开更多
关键词 germinated rice nutritional aspect germination condition DIGESTIBILITY ADVANTAGE
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Drug Seeking Behavior of Amphetamine Addicted Sprague-Dawley Rats Is Eliminated after Nutritional Supplementation 被引量:2
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作者 Annice Webber-Waugh Karen Thaxter Nesbeth +3 位作者 Pauline Anderson-Johnson Ajibike Salako-Akande Helen Asemota Lauriann Young 《Journal of Behavioral and Brain Science》 2017年第12期585-597,共13页
Aim: The effectiveness of nutritional supplementation on drug-seeking behavior of amphetamine-addicted rats during withdrawal was investigated using a biased conditioned place preference (CPP) paradigm. Method: Twenty... Aim: The effectiveness of nutritional supplementation on drug-seeking behavior of amphetamine-addicted rats during withdrawal was investigated using a biased conditioned place preference (CPP) paradigm. Method: Twenty-four male Sprague-Dawley rats exhibiting baseline preference for the black chamber during a 20-minute pre-conditioning exploration of the CPP box completed the study. On alternate days of an 8-day schedule, twelve rats (Group AMP) were randomly selected, given either amphetamine sulfate (5 mg/ml, i.p.) and confined to the white chamber;or vehicle (1 ml saline, i.p.) and confined to the black chamber. A significant increased percentage time spent and number of entries made by Group AMP to the drug-paired, white chamber on the test day confirmed amphetamine addiction. Group AMP subsequently received increasing doses of amphetamine over 6 days. Following acute drug withdrawal, their CPP performance was compared with that of vehicle treated rats (Group SAL). Groups AMP and SAL were equally divided and randomly assigned to animals fed chow reconstituted with the nutritional supplement (AMP-S and SAL-S) over 8 weeks or standard rat chow (AMP-N and SAL-N). CPP performances for all rats were determined blindly from video recordings following this period. Results: Nutritionally supplemented, amphetamine withdrawn rats (AMP-S) exhibited significantly decreased percentage entries and time spent in the white chamber (p ?ve, control animals. Conclusion: Drug-seeking behavior by amphetamine-addicted animals was eliminated after treatment with a nutritionally supplemented diet. 展开更多
关键词 AMPHETAMINE conditioned PLACE PREFERENCE nutritionAL SUPPLEMENT ADDICTION Animal Model
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Effects of fermentation conditions on bioactive substances in lactic acid bacteria-fermented soymilk and its storage stability assessment 被引量:2
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作者 Philippe Madjirebaye Fei Peng +11 位作者 Tao Huang Zhanggen Liu Abdul Mueed Majeste Mbiada Pahane Qianqian Guan Muyan Xiao Tonghao Du Benliang Wei Shijin Xiong Linli Zhang Tao Xiong Zhen Peng 《Food Bioscience》 SCIE 2022年第6期1913-1924,共12页
The consumption of fermented soymilk(FSM)is of great interest to consumers because of its many potential health benefits.Nevertheless,soymilk's unpleasant flavor and astringent taste are a major concern in consump... The consumption of fermented soymilk(FSM)is of great interest to consumers because of its many potential health benefits.Nevertheless,soymilk's unpleasant flavor and astringent taste are a major concern in consumption.To obtain the soymilk with good flavor and functionality profiles,fermentation is one of the alternatives,which is why Lactobacillus plantarum NCU001563 and Streptococcus thermophilus NCU074001 were selected and used through different fermentation conditions(DFC).The single-factor test and orthogonal experiment comprehensively determine the FSM production process.The parameters of optimal conditions include mixed fermentation agents,water ratio(1:5),sterilization time(15 min),sterilization temperature(105℃),160-mesh press cloth,carbon source(glucose),amount of glucose(10%),inoculum amount(0.03%),fermented soymilk temperatures(FSM3,37℃;FSM4,42℃),and fermentation time(24 h)were retained.The DFC significantly affects nutritional factors such as proteins,amino acids,and others.At the same time,the anti-nutritional components showed the opposite results,except the total phenolic content exhibited a significantly higher content after fermentation.However,the DFC significantly decreased aldehydes such as hexanal in non-fermented soymilk(NFSM)from 19.30%to 4.97%in FSM3 and 1.60%in FSM4,respectively.Furthermore,the fermentation produced a higher abundance of 2-butanone,acetoin,and acetic acids,thus improving the overall sensory acceptability.Over time,the fermentation has been pertinent to exert preservation effects,especially for FSM4 at 4℃.The results indicated that the optimized DFCs have a good application for FSM by improving its flavor,functional profiles with health-promoting effects,and soymilk product preservations. 展开更多
关键词 Fermented soymilk nutritional and anti-nutritional profiles Volatile factors Storage conditions
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Drug-Seeking Behavior Is Significantly Attenuated in Nutritionally Supplemented Cocaine Withdrawn Sprague-Dawley Rats 被引量:1
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作者 Lauriann Young Annice Webber-Waugh Karen Thaxter 《Journal of Behavioral and Brain Science》 2021年第7期143-156,共14页
<b>Aim:</b> The effect of patented nutritional supplementation on drug-seeking behavior in cocaine addicted rats during acute drug withdrawal was investigated using a biased Conditioned Place Preference (C... <b>Aim:</b> The effect of patented nutritional supplementation on drug-seeking behavior in cocaine addicted rats during acute drug withdrawal was investigated using a biased Conditioned Place Preference (CPP) paradigm. <b>Method:</b> Twenty-four (24) male Sprague-Dawley rats with pre-conditioned preference for the black chamber of the CPP box were randomly divided into Cocaine (COC) or Saline (SAL) treated groups. Rats (n = 12) treated with cocaine hydrochloride 20 mg/kg/ml, <i>i.p.</i> (COC group) were confined individually to the white chamber on days 1, 3, 5 and 7. On alternate days, they were given 1 ml saline vehicle, <i>i.p.</i> and confined to the black chamber. Control rats (SAL group, n = 12) received only vehicle on all 8 days and were confined on alternate days to the white or black chamber. Positive place preference was confirmed for COC rats, which subsequently received 6 increasing daily doses of cocaine. CPP performances of both COC and SAL rats were recorded following an acute 3-day withdrawal period. All animals were then randomly assigned to rats fed either chow reconstituted with the nutritional supplement (COC-S and SAL-S) or standard rat chow (COC-N and SAL-N) for 8 weeks, followed by final CPP performances. <b>Results:</b> Following supplementation, COC-S rats made significantly less entries and time spent in the white chamber (p < 0.05) compared with COC-N rats. COC-S rats exhibited significant place aversion to the white chamber similar to drug-naive animals;whereas COC-N continued to show positive place preference. <b>Conclusion:</b> Drug-seeking behavior that persisted during cocaine withdrawal was significantly diminished in the nutritionally supplemented. 展开更多
关键词 COCAINE conditioned Place Preference nutritional Supplement ADDICTION Drug-Seeking Behavior
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A comparison of several indices for assessing body condition of Mongolian gazelle
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作者 李俊生 周宏力 +1 位作者 袁力 张冬梅 《Journal of Forestry Research》 SCIE CAS CSCD 2000年第4期245-248,共4页
Riney kidney fat index (RKFI), whole kidney fat index (WKFI), femur marrow fat index (FMFI), and tibia marrow fat index (TMFI) of 51 Mongolian gazelles (Procapra gutturosa), collected in Hulunbeier grassland, Inner Mo... Riney kidney fat index (RKFI), whole kidney fat index (WKFI), femur marrow fat index (FMFI), and tibia marrow fat index (TMFI) of 51 Mongolian gazelles (Procapra gutturosa), collected in Hulunbeier grassland, Inner Mongolian, China, were measured during spring, autumn and winter in 1997-98. These different indexes were compared for using them in assessing the body condition. There was a linear relationship (y=0.9444x-20.139; r=0.9454; p<0.01) between RKFI and KMFI. A linear relationship (y=0.9348x+1.1843; r=0.9875; P<0.01) between TMFI and FMFI also occurred for gazelles. There was a curvilinear relationship (y=31.44Ln(x) -44.403; r=0.8643; P<0.01) between FMFI and RKFI. FMFI remained high, while RKFI decreased to a certain extent. After most of the kidney fat was used, the femur marrow fat abruptly decreased. The results showed that the kidney fat index is more adequate for evaluating the population nutrition in good condition, but marrow fat index was more useful for assessing in poorer nutritional condition. 展开更多
关键词 Procapra gutturosa fat indexes nutritional condition assessment
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Dietary fat intake of Japanese male children and its associated factors: Results of the 1995 National Nutrition Survey in Japan
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作者 Minako Koga Kohta Suzuki +6 位作者 Yasuhisa Takeda Naoki Kondo Yasuhiro Matsumura Shigenori Oguri Akira Okayama Hiroshi Yanagawa Zentaro Yamagata 《Health》 2012年第12期1396-1404,共9页
Aim: To clarify the factors associated with reported dietary fat intake by Japanese male children. Methods: This study is based on the data of a nationally representative cross-sectional study in Japan. Three hundred ... Aim: To clarify the factors associated with reported dietary fat intake by Japanese male children. Methods: This study is based on the data of a nationally representative cross-sectional study in Japan. Three hundred and seventy-seven male children (age, 6 - 11 years) whose households were sampled in the 1995 Comprehensive Survey of Living Conditions of the People on Health and Welfare, and the 1995 National Nutrition Survey and whose parents were identified through record linkage between the 2 survey data sets were enrolled. Results: The final dataset in this study consisted of 377 boys with 329 of their parents. Fifty-two boys were found to be overweight (13.8%). The reported dietary fat intake was higher among the overweight boys than among the non-overweight boys. Maternal obesity was significantly associated with obesity in male children. Boys who frequently consumed foods from the “fats and lipids” group and the “meat” groups, and children from nuclear families rather than 3- generation families reported high dietary fat intake. In addition, parental fat intake was also significantly associated with fat intake of male children. Conclusions: Child and parental dietary habits along with the household status should be considered when implementing nutritional education programmes to control dietary fat intake and reduce the obesity risks of male children. 展开更多
关键词 CHILDHOOD Obesity DIETARY Fat INTAKE NATIONAL nutrition SURVEY Comprehensive SURVEY of Living conditions of the People on Health and WELFARE
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Effects of grazing intensity to water source on grassland condition, yield and nutritional content of selected grass species in Northwest Ethiopia 被引量:4
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作者 Yaregal Melak Ayana Angassa Aster Abebe 《Ecological Processes》 SCIE EI 2019年第1期149-161,共13页
Background:Savanna grasslands are globally important ecosystems consisting of one of the most extensive grazing lands with unique biodiversity.The objectives of the study were to assess the effect of grazing intensity... Background:Savanna grasslands are globally important ecosystems consisting of one of the most extensive grazing lands with unique biodiversity.The objectives of the study were to assess the effect of grazing intensity on grassland ecosystem condition,herbaceous plant biomass production,and nutritional content of selected grass species.Methods:The study was conducted at Chagni Ranch,Northwest Ethiopia.Four transects to water source point at regular intervals of 20m between sampling plots along transects were used for data collection.The distance between the four transects was 200m in radius.Data were collected on grass composition,basal cover,litter cover,number of seedlings,and age distribution of dominant grasses(i.e.,young,medium,or old in terms of stage of maturity),soil condition in terms of soil compaction,and soil erosion linked to the effects of trampling by grazing animals along transects(hereafter referred to as transect)to water source point.The total sample size for grass species was 160 plots.The grassland ecosystem condition,herbaceous biomass,and grass nutritional content were used as response variables linked to transect from water source point.The effects of transect on grassland ecosystem condition scores and grass nutritional content were analyzed using the analysis of variance(ANOVA).Results:Grassland condition factors like grass composition,basal cover,litter cover,age distribution of dominant grasses,and soil condition were significantly(P<0.05)higher for the furthest transect to water source point than nearest transect.Out of the 28 identified herbaceous species,grasses accounted for 64.3%of the herbaceous community.Within grass species,about 55.6%were highly desirable in terms of palatability and grazing value(as most palatable species are susceptible to heavy grazing intensity).The results showed a significantly(P<0.05)higher proportion of perennial grasses at the furthest transect to water source point than nearest transect.The dry matter yield at the furthest transect(TD4)and third transect(TD3)were significantly(P<0.05)higher than the nearest transect to water source point(i.e.,the first transect(TD1)and second transect(TD2)).Ash,neutral detergent fiber,acid detergent fiber,and acid detergent lignin contents of Cynodon dactylon,Sporobolus pyramidalis,and Digitaria ternata were significantly(P<0.05)higher at the furthest transect to water source point than nearest transect.Grazing intensity had no significant effect on the crude protein content of Cynodon dactylon and Sporobolus pyramidalis at different transects.Conclusions:The results showed that the furthest transect to water source point were in good condition.Grass biomass production and the nutritional contents of grasses were higher for the furthest transect to water source point.The results suggested that increased grazing intensity towards water source point greatly reduced the abundance of desirable perennial grasses and the sustainability of grassland for livestock production. 展开更多
关键词 Grassland condition Grass yield nutritional content TRANSECT
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三联预康复策略对宫颈癌患者心理与营养状况的影响
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作者 王晓苏 《中外女性健康研究》 2024年第11期17-20,共4页
目的:探讨与分析三联预康复策略对宫颈癌患者心理与营养状况的影响。方法:2019年8月至2023年1月选择在本院诊治的宫颈癌患者78例作为研究对象,根据1:1随机掷骰子原则把78例患者分为三联组39例与传统组39例。传统组给予常规护理,三联组... 目的:探讨与分析三联预康复策略对宫颈癌患者心理与营养状况的影响。方法:2019年8月至2023年1月选择在本院诊治的宫颈癌患者78例作为研究对象,根据1:1随机掷骰子原则把78例患者分为三联组39例与传统组39例。传统组给予常规护理,三联组在传统组护理的基础上实施三联预康复策略护理,两组护理观察时间为3个月,记录与判定患者心理与营养状况变化情况。结果:三联组护理3个月期间的肺部感染、尿路感染、静脉血栓、压疮、尿潴留等并发症发生率为5.13%,显著低于传统组的25.64%(P<0.05)。两组护理3个月后的血清血红蛋白与白蛋白含量显著高于护理前(P<0.05),三联组护理3个月后的血清血红蛋白、白蛋白含量明显高于传统组(P<0.05)。护理3个月后两组焦虑SAS评分与抑郁SDS评分较护理前都显著降低(P<0.05),且观察组护理3个月后的焦虑SAS评分、抑郁SDS评分与传统组相比也显著降低(P<0.05)。护理3个月后三联组的生活质量评分与传统组相比有明显降低(P<0.05)。结论:三联预康复策略在宫颈癌患者的应用能降低并发症发生率,改善患者的营养状况与生活质量,缓解负性情绪,有很好的应用价值。 展开更多
关键词 三联预康复策略 宫颈癌 营养状况 心理状况
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微生物碳酸盐生产工厂的构成、特征及沉积学意义——以河南云梦山剖面为例 被引量:1
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作者 王曾俊 李飞 +4 位作者 李杨凡 李怡霖 曾伟 李雅兰 李滢 《沉积学报》 CAS CSCD 北大核心 2024年第2期403-414,共12页
【目的】“碳酸盐(生产)工厂”研究强调生物群落对碳酸盐生产过程以及规模的调控和特异性影响,在深入认识碳酸盐岩成因和形成机制方面具有重要价值,是碳酸盐沉积学领域关注热点和重要方向。虽然该概念的正式提出已有二十多年历史,但如... 【目的】“碳酸盐(生产)工厂”研究强调生物群落对碳酸盐生产过程以及规模的调控和特异性影响,在深入认识碳酸盐岩成因和形成机制方面具有重要价值,是碳酸盐沉积学领域关注热点和重要方向。虽然该概念的正式提出已有二十多年历史,但如何从工厂角度解读地质历史时期,特别是深时特异性、大规模碳酸盐岩的发育过程和影响因素方面仍缺乏系统性认识。【方法】以河南云梦山剖面寒武系崮山组为例,利用多尺度、网格定量化评价方法对微生物碳酸盐生产工厂的样式、内部结构、建造过程等方面进行了详细阐述。【结果】研究区微生物碳酸盐生产工厂以底栖微生物群落为主要建造者,形成样式包括叠层石、凝块石、树枝石、均一石以及微生物诱导沉积构造(MISS)。伴生的颗粒类型包括鲕粒、球粒、生屑、竹叶状内碎屑和微生物岩角砾,主要分布于工厂建造格架间。微生物碳酸盐生产工厂发育具期次性,单期工厂发育规模较小(海底至水面高度不足1 m)但空间延伸广,包括半球状、穹窿状、板状等宏观形态;其内部结构包括少量单独的建造样式,以及广泛发育的垂向复合形式。【结论】通过分析影响工厂发育的各类因素,局限潮坪环境下较高的营养水平对微生物碳酸盐生产工厂的繁盛可能起到了主要作用,而古丈期总体海侵背景造成适宜微生物碳酸盐生产工厂发育的环境消失,导致工厂最终关闭。相关工作的开展提供了一个与现代澳大利亚Hamelin Pool微生物碳酸盐生产工厂非常相似的古代实例,对认识寒武纪碳酸盐生产工厂类型、特征和演化规律方面具有较好的参考价值。 展开更多
关键词 微生物岩 碳酸盐沉积过程 营养条件 古丈期 华北板块
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基于菌丝生物量和胞外多糖产量的Simplicillium lanosoniveum液体发酵培养条件优化
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作者 李昕阳 杨阳 +5 位作者 刘栋 刘宇光 刘俊泽 陈长宝 王欢 王淑敏 《生物技术进展》 2024年第6期937-946,共10页
真菌Simplicillium lanosoniveum已被报道具有多种生物学效应,往往被用作生物防治。然而,有关其液体发酵的研究却很少。通过形态学和系统发育分析,鉴定了1株从发网菌属中分离出的丝孢真菌SL001,即S.lanosoniveum。以菌丝生物量和胞外多... 真菌Simplicillium lanosoniveum已被报道具有多种生物学效应,往往被用作生物防治。然而,有关其液体发酵的研究却很少。通过形态学和系统发育分析,鉴定了1株从发网菌属中分离出的丝孢真菌SL001,即S.lanosoniveum。以菌丝生物量和胞外多糖产量为指标,通过单因素和正交实验优化发酵培养基的组成和比例,以阐明液体发酵S.lanosoniveum的最优培养条件。结果表明,在麦芽糖40 g·L^(-1)、蛋白胨3 g·L^(-1)和KH_(2)PO_(4)1 g·L^(-1)的营养条件下,S.lanosoniveum的菌丝生物量和胞外多糖产量最高,对S.lanosoniveum菌丝生物量的影响程度由大到小依次为麦芽糖>蛋白胨>KH_(2)PO_(4)。最后,根据营养需求对培养条件进一步优化。结果显示,最佳培养条件为麦芽糖40 g·L^(-1),蛋白胨3 g·L^(-1),KH2PO41 g·L^(-1),培养温度28℃,pH 5.5,转速150 r·min-1,装液量80 mL/250 mL,接种量6%。在最佳培养条件下,菌丝生物量和胞外多糖可达到最大值1.69 g·100 mL^(-1)和3.968 mg·ml^(-1),与对照组相比有显著差异(P<0.01)。通过单因素和正交实验得到真菌S.lanosoniveum的最佳液体发酵条件,为进一步研究S.lanosoniveum的抗菌作用和工业化生产提供了理论依据。 展开更多
关键词 S.lanosoniveum 液体发酵 营养成分 培养条件 菌丝生物量 胞外多糖含量
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2023年《ESPEN指南:共病住院患者营养支持》解读
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作者 吴太琴 甘秀妮 +2 位作者 高燕 张欢 阳莉 《中国全科医学》 CAS 北大核心 2024年第21期2557-2564,共8页
由于我国人口老龄化趋势加快和居民生活行为方式的转变,致使慢性病共病成为公众健康的一大挑战。共病现象使患者病情更加复杂、营养状况不佳,给患者健康和社会造成沉重负担。2018年,欧洲临床营养和代谢学会(ESPEN)发布了《共病住院患者... 由于我国人口老龄化趋势加快和居民生活行为方式的转变,致使慢性病共病成为公众健康的一大挑战。共病现象使患者病情更加复杂、营养状况不佳,给患者健康和社会造成沉重负担。2018年,欧洲临床营养和代谢学会(ESPEN)发布了《共病住院患者营养支持指南》,从共病住院患者的营养筛查、评估、需求、监测和干预等方面提供了22项建议和4项声明。基于不断更新的研究证据,2023年6月ESPEN指南工作组对2018版指南进行了更新,即2023年《ESPEN指南:共病住院患者营养支持》,为共病住院患者提供了基于最新循证证据的营养支持建议。本文对该指南进行解读,并就营养筛查和评估、口服营养补充、肠内营养和肠外营养、能量需求量的估算、蛋白质目标量、微量营养素的补充、特定疾病的营养补充、早期营养支持、出院后营养支持、身体功能检测、能量和蛋白质达标量、营养支持的组织管理、基础疾病对营养支持的影响、药物或营养素相互作用、营养生物标志物共15个方面进行重点分析,旨在为我国临床共病住院患者营养管理实践提供指导。 展开更多
关键词 慢性病共病 共病 共病现象 营养支持 管理 指南 解读
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昆明市老年人营养状况及营养不良风险评估分析 被引量:1
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作者 刘国华 熊光轶 +3 位作者 邱珺 李胜江 汤滴微 张珊 《中国健康教育》 北大核心 2024年第7期631-638,共8页
目的开展昆明市老年人营养不良风险评估及了解营养状况。方法2020年9—12月采用多阶段抽样方法抽取3737名65岁以上老年人,使用WS/T552-2017《老年人营养不良风险评估》开展调查,应用等级Logistic回归模型分析营养不良风险影响因素。结果... 目的开展昆明市老年人营养不良风险评估及了解营养状况。方法2020年9—12月采用多阶段抽样方法抽取3737名65岁以上老年人,使用WS/T552-2017《老年人营养不良风险评估》开展调查,应用等级Logistic回归模型分析营养不良风险影响因素。结果1813人(48.51%)初筛总分<12分,需继续评估,营养不良率和营养不良风险率分别为20.74%和56.15%,而营养良好率为23.11%。消瘦(OR=1.435,95%CI:1.034~1.990)、患慢性病>3种(OR=1.833,95%CI:1.461~2.303)、长期服药种类>3种(OR=2.167,95%CI:1.747~2.762)、睡眠时间<5 h/d(OR=1.697,95%CI:1.416~2.032)、户外独立活动时间<1 h/d(OR=1.952,95%CI:1.590~2.396)、经济状况差和一般(OR=1.723,95%CI:1.209~2.457和OR=1.644,95%CI:1.404~1.925)、进食需要依靠别人和稍有困难(OR=14.126,95%CI:9.994~19.945和OR=3.065,95%CI:2.319~4.055)、餐次为2次/d(OR=1.682,95%CI:1.392~2.030)、摄入奶/豆/鱼/肉/禽/蛋类<3种/d(OR=1.637,95%CI:1.381~1.941)、烹调油摄入量>25g/d(OR=1.737,95%CI:1.499~2.012)和蔬菜水果<500 g/d(OR=1.800,95%CI:1.531~2.117)是老年人发生营养不良风险的主要危险因素。结论昆明市社区65岁以上老年人营养状况不佳,当地社区卫生服务中心(站)或公共营养机构应开展多种形式的营养教育与营养干预,改善老年人营养状况。 展开更多
关键词 营养状况 营养不良风险评估 老年人 昆明市
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超声双重造影参数、预后营养指数对胃癌伴腹膜转移患者预后的预测价值分析
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作者 马冬玲 张梦娇 +3 位作者 孙学芹 巧丽潘·玉奴斯 沈建强 刘小莉 《中国医刊》 CAS 2024年第4期417-423,共7页
目的探讨超声双重造影(DCEUS)参数、预后营养指数(PNI)对胃癌伴腹膜转移患者预后的预测价值。方法选取2021年1月至2022年1月新疆克孜勒苏柯尔克孜自治州人民医院收治的90例胃癌伴腹膜转移患者作为观察组,另选取同期新疆克孜勒苏柯尔克... 目的探讨超声双重造影(DCEUS)参数、预后营养指数(PNI)对胃癌伴腹膜转移患者预后的预测价值。方法选取2021年1月至2022年1月新疆克孜勒苏柯尔克孜自治州人民医院收治的90例胃癌伴腹膜转移患者作为观察组,另选取同期新疆克孜勒苏柯尔克孜自治州人民医院收治的90例未伴腹膜转移的胃癌患者作为对照组,比较分析两组DCEUS参数,包括基础强度(BI)、峰值强度(PI)、开始增强时间(RT)、到达峰值时间(TTP)、增强强度(EI)及PNI。同时分析胃癌伴腹膜转移患者的生存状况,DCEUS参数、PNI与胃癌伴腹膜转移患者临床病理因素的关系及对这类患者预后的预测价值。结果观察组DCEUS参数BI、PI、EI高于对照组,RT、TTP及PNI低于对照组,差异均有统计学意义(P<0.05)。胃癌伴腹膜转移患者DCEUS参数BI、PI、EI、RT、TTP与肿瘤T分期、腹膜转移分级、有无腹水、血清癌胚抗原、糖类抗原19-9水平及姑息性胃切除联合术后化疗评分有关(P<0.05),PNI与腹膜转移分级、血红蛋白、血小板与淋巴细胞比值、中性粒细胞与淋巴细胞比值、白蛋白及姑息性胃切除联合术后化疗评分有关(P<0.05)。观察组90例患者中位生存时间为11.7个月,1年生存率仅47.78%;Kaplan-Meier曲线分析显示,BI、PI、EI高水平患者1年生存率低于低水平患者,RT、TTP及PNI高水平患者1年生存率高于低水平患者,差异均有统计学意义(P<0.05)。多因素Cox回归分析结果显示,肿瘤T分期、腹膜转移分级、姑息性胃切除联合术后化疗评分、BI、PI、EI为胃癌伴腹膜转移患者预后的独立危险因素(P<0.05),白蛋白、RT、TTP及PNI为独立保护因素(P<0.05)。受试者操作特征曲线分析显示,BI、PI、EI、RT、TTP及PNI联合预测胃癌伴腹膜转移患者预后的曲线下面积为0.909,明显大于各指标单独预测(P<0.05)。结论DCEUS参数BI、PI、EI、RT、TTP及PNI与胃癌伴腹膜转移病情进展有一定关系,联合预测胃癌伴腹膜转移患者预后的价值较为可靠,具有重要的临床意义。 展开更多
关键词 胃癌 腹膜转移 超声双重造影 预后营养指数 生存状况 预测价值
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烟台地黄瓜嫁接苗和自根苗生长状况比较
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作者 郑豪 孟俊成 于立芝 《农学学报》 2024年第10期47-52,共6页
本研究旨在比较嫁接苗与自根苗烟台地黄瓜在生长状况上的差异,并明确嫁接对烟台地黄瓜生长发育的影响。通过田间试验,对比了2种类型黄瓜的的植物学性状、果实性状、营养品质、感官质量及产量。结果表明,嫁接对烟台地黄瓜株高、茎粗、节... 本研究旨在比较嫁接苗与自根苗烟台地黄瓜在生长状况上的差异,并明确嫁接对烟台地黄瓜生长发育的影响。通过田间试验,对比了2种类型黄瓜的的植物学性状、果实性状、营养品质、感官质量及产量。结果表明,嫁接对烟台地黄瓜株高、茎粗、节间长有一定的促进作用;嫁接基本保留了烟台地黄瓜果实的优良性状;嫁接苗烟台地黄瓜维生素C含量有明显下降,嫁接苗烟台地黄瓜的果型、色泽喜好度高于自根苗黄瓜,嫁接苗烟台地黄瓜的果肉颜色、甜味、水分、黄瓜味、涩味、苦味、整体喜好度要低于自根苗黄瓜,二者差异未达到显著水平;嫁接可以提高烟台地黄瓜产量,增加黄瓜单果重。综上,嫁接苗与自根苗烟台地黄瓜生长状况有一定的差异。 展开更多
关键词 烟台地黄瓜 嫁接苗 自根苗 生长 生长状况 感官评价 感官质量 产量 果实性状 营养品质
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冷冻条件对细鳞鲑肌肉营养成分的影响
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作者 宁可源 李永雄 +2 位作者 玄一凡 梁潇 王茂林 《安徽农业科学》 CAS 2024年第16期160-162,257,共4页
利用日立L-8800型氨基酸分析仪和Agilent 6890-5973N型气相色谱-质谱联用仪分析新鲜细鳞鲑和细鳞鲑在-20℃冷冻12 h后肌肉氨基酸、脂肪酸含量,并对细鳞鲑肌肉冷冻后口感的影响程度进行分析。结果表明,细鳞鲑在鲜活和冷冻2种条件下肌肉... 利用日立L-8800型氨基酸分析仪和Agilent 6890-5973N型气相色谱-质谱联用仪分析新鲜细鳞鲑和细鳞鲑在-20℃冷冻12 h后肌肉氨基酸、脂肪酸含量,并对细鳞鲑肌肉冷冻后口感的影响程度进行分析。结果表明,细鳞鲑在鲜活和冷冻2种条件下肌肉中大部分氨基酸、脂肪酸含量有显著差异。冷冻会一定程度上减少肌肉的C18:1n-9、C16:1n-7、C17:1n-7等脂肪酸以及谷氨酸、甘氨酸等氨基酸,但仍是优质的氨基酸、脂肪酸来源。 展开更多
关键词 细鳞鲑 冷冻条件 肌肉 营养成分
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早期科学肠内营养支持改善胃癌患者术后身体状态及睡眠的效果研究
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作者 叶雪花 《世界睡眠医学杂志》 2024年第10期2390-2392,共3页
目的:探讨胃癌患者康复中应用早期科学肠内营养支持的价值。方法:选取2023年1月至2024年2月福建省立医院收治的胃癌患者82例作为研究对象,按照随机数字表法分为对照组和观察组,每组41例。对照组实施肠外营养支持,观察组实施早期科学肠... 目的:探讨胃癌患者康复中应用早期科学肠内营养支持的价值。方法:选取2023年1月至2024年2月福建省立医院收治的胃癌患者82例作为研究对象,按照随机数字表法分为对照组和观察组,每组41例。对照组实施肠外营养支持,观察组实施早期科学肠内营养支持。比较2组身体状态、睡眠质量。结果:护理实施后,与对照组比较,观察组身体状态恢复情况更理想,差异有统计学意义(P<0.05);观察组睡眠质量评分较对照组下降范围更大,差异有统计学意义(P<0.05)。结论:胃癌患者康复中应用早期科学肠内营养支持效果理想。 展开更多
关键词 胃癌 早期科学肠内营养支持 身体状态 睡眠质量 恶性肿瘤 护理 住院时间 胃肠功能
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