Two new secolignans from the roots of Urtica mairei Levi.

Two new secolignans （1 and 2） were isolated from the roots of Urtica mairei Levi. The structures of these two compounds were determined on the basis of extensive spectroscopic methods including HR-EI-MS, 1D and 2D NMR experiments.

The naturally occurring secolignans

Naturally occurring secolignans have drawn the considerable attention because of their novel structures and diverse biological activities.In recent years,various natural secolignans with extensive bioactivities have been reported in the literatures.In the present review,we summarized all the available information regarding the biosynthesis,distributions,separation methods,chemical structures,spectral characteristics,and biological activities of natural secolignans,and provided some valuable new insights for the further study.

天然产物中裂木脂素类化合物的研究进展

目的对天然来源的裂木脂素类化合物的结构、生物合成及药理活性进行综述,为该类化合物的进一步研究奠定基础。方法根据裂木脂素类化合物的24篇相关文献进行综述总结。结果近年来从草胡椒属、荨麻属及卷柏属植物中发现多种结构新颖的裂木脂素类化合物,该类化合物在抗肿瘤、抗艾滋病病毒等方面有很强的生物活性。结论裂木脂素类化合物具有广阔的开发利用前景。