Study on the Effect of Self-Help Mindfulness Therapy on Rumination in Patients with Depression

Objective:To evaluate the nursing effect of self-help mindfulness therapy for patients with depression.Methods:120 cases of depression patients admitted to the Department of Psychosomatic Disorders of our hospital between January 2020 and January 2023 were selected.After being grouped by the random draw method,60 cases in the observation group adopted self-help mindfulness therapy and 60 cases in the control group adopted conventional nursing care,the nursing effects were subsequently compared.Results:Before nursing,there was no difference in the comparison of clinical symptom scores,rumination scores,positive psychological scores,and self-esteem scores between the two groups(P>0.05).After nursing,the clinical symptom scores of the observation group were lower than those of the control group;the rumination scores were lower than those of the control group;the positive psychological scores were higher than those of the control group;and the self-esteem scores were higher than those of the control group,and all of them were statistically significant(P<0.05).Conclusion:Self-help mindfulness therapy can improve the clinical symptoms of patients with depression and their rumination,and enhance their positive psychological state and self-esteem level,which has high nursing advantages.

Neural mechanisms of mindfulness and meditation: Evidence from neuroimaging studies

Mindfulness is the dispassionate,moment-by-moment awareness of sensations,emotions and thoughts.Mindfulness-based interventions are being increasingly used for stress,psychological well being,coping with chronic illness as well as adjunctive treatments for psychiatric disorders.However,the neural mechanisms associated with mindfulness have not been well characterized.Recent functional and structural neuroimaging studies are beginning to provide insights into neural processes associated with the practice of mindfulness.A review of this literature revealed compelling evidence that mindfulness impacts the function of the medial cortex and associated default mode network as well as insula and amygdala.Additionally,mindfulness practice appears to effect lateral frontal regions and basal ganglia,at least in some cases.Structural imaging studies are consistent with these findings and also indicate changes in the hippocampus.While many questions remain unanswered,the current literature provides evidence of brain regions and networks relevant for understanding neural processes associated with mindfulness.

Does mindfulness meditation improve attention in attention deficit hyperactivity disorder?

Attention deficit hyperactivity disorder(ADHD) manifests by high levels of inattention, impulsiveness and hyperactivity. ADHD starts in childhood and results in impairments that continue into adulthood. While hyperactivity declines over time, inattention and executive function difficulties persist, leading to functional deficits. Adolescents and adults with ADHD have pervasive impairment in interpersonal and family relationships. They may develop addiction, delinquent behavior and comorbid psychiatric disorders. Despite advances in diagnosis and treatment, persistent residual symptoms are common, highlighting the need for novel treatment strategies. Mindfulness training, derived from Eastern meditation practices, may improve self-regulation of attention. It may also be a useful strategy to augment standard ADHD treatments and may be used as a potential tool to reduce impairments in patients with residual symptoms of ADHD. Clinically, this would manifest by an increased ability to suppress task-unrelated thoughts and distractions resulting in improved attention, completion of tasks and potential improvement in occupational and social function.

Effects of mindfulness meditation on anxiety, depression, stress, and mindfulness in nursing students: a meta-analysis and trial sequential analysis of randomized controlled trials

Objective:The aim of this study was to assess the effectiveness of mindfulness meditation(MM)on anxiety,depression,stress and mindfulness in nursing students.Methods:A comprehensive search and screening procedures were conducted to locate all MM interventions implemented with nursing students.For randomized controlled trials(RCTs)in accordance with the inclusion criteria,a search was conducted in PubMed,Embase,Web of Science,Medline,PsycINFO,Cumulative Index to Nursing and Allied Health(CINAHL),Cochrane Central Register of Controlled Trials(CENTRAL),China Biology Medicine(CBM),Chinese National Knowledge Infrastructure(CNKI)and Wanfang.Databases were retrieved from inception through August 2018.Additional studies were identified through hand searches and Internet searches.Two reviewers collected relevant data of eligible articles according to the data extraction tables.Based on Cochrane Handbook,critical appraisal of the methodological quality was assessed by two other reviewers.An Excel form was used to extract main characteristics of included RCTs.Meta-analysis and trial sequential analysis(TSA)were carried out using software RevMan 5.3 and TSA 0.9.Results:Five RCTs with 257 nursing students were included.Only two studies were assessed as high quality and three studies were evaluated as moderate quality.Meta-analysis showed that,comparing with the control group,MM could significantly improve anxiety(SMD=?0.45,95%CI?0.73 to?0.17,P=0.001)and stress(SMD=?0.69,95%CI?0.97 to?0.40,P<0.001).TSA results confirmed that the outcome of the merger is credible.It could also significantly improve depression level of nursing students after 8 weeks intervention duration(SMD=?0.70,95%CI?1.14 to?0.26,P=0.002).However,there was no beneficial effect on depression level of nursing students with 1 week intervention duration(SMD=0.09,95%CI?0.42 to 0.59,P=0.74)and its effects on mindfulness level of nursing students also did not show statistical significance(SMD=0.37,95%CI?0.04 to 0.77,P=0.07).No definitive conclusions were drawn from the TSA.Conclusions:The results of this meta-analysis indicated that MM could effectively reduce the level of anxiety and stress of nursing students.TSA confirmed that the results of meta-analysis are credible.For depression,it could also significantly improve depression of nursing students with 8 weeks intervention,but there was no significant effect on nursing students with 1 week intervention duration.There was also no beneficial effect on mindfulness level of nursing students.However,TSA indicated that the accumulated evidence is still inconclusive.We suggest that more well-designed clinical trials with large sample and higher quality would be required in future to draw a definitive conclusion.

Effects of mindfulness meditation on trait mindfulness,perceived stress,emotion regulation,and quality of life in hemodialysis patients:A randomized controlled trial

Objective:This study aimed to examine the effects of mindfulness meditation on trait mindfulness,perceived stress,emotion regulation,and quality of life in end-stage renal disease patients undergoing hemodialysis.Methods:An experimental study with repeated measures design was conducted among a sample of 74 end-stage renal disease patients undergoing hemodialysis between January and May 2021 in the dialysis center at Jahra hospital,Kuwait.The patients were randomly assigned to the experimental(n?37)and control groups(n?37).The experimental group participated in 30-min mindfulness meditation sessions(three sessions a week for five weeks)held during their hemodialysis sessions;the participants in the control group were instructed to sit with their eyes closed and relaxed for 30 min three times a week for five weeks during hemodialysis sessions.The dependent variables of both groups were measured at baseline(T0),middle of intervention(T1),and end of intervention(T2)using the Mindful Attention Awareness Scale(MAAS),Perceived Stress Scale(PSS),Emotion Regulation Questionnaire(ERQ),and Kidney Disease Quality of Life(KDQOL-36)questionnaire.The study was registered in the ClinicalTrial.gov(Identifier:NCT05176730).Results:The repeated measures ANOVA(within-subject)results for the experimental group showed that mindfulness meditation had significantly decreased perceived stress by the end of the intervention.Also,mindfulness meditation improved mindfulness,emotion regulation,and kidney disease-related quality of life in the experimental group,and this improvement occurred significantly at both T1 and T2.The repeated measures ANOVA(within and between-subject)results showed that the experimental group,as compared to the control group,had lower perceived stress,higher trait mindfulness,higher emotional regulation,and higher kidney disease-related quality of life over time.Conclusions:The positive findings of this study offer health policy-makers and hospital administrators a promising tool to use with patients undergoing hemodialysis as a way to manage stress and improve quality of life.However,this study should be replicated in multiple settings with follow-up assessments.

Underlying mechanisms of mindfulness meditation:Genomics,circuits,and networks

Understanding neuropsychological mechanisms of mindfulness meditation(MM)has been a hot topic in recent years.This review was conducted with the goal of synthesizing empirical relationships via the genomics,circuits and networks between MM and mental disorders.We describe progress made in assessing the effects of MM on gene expression in immune cells,with particular focus on stressrelated inflammatory markers and associated biological pathways.We then focus on key brain circuits associated with mindfulness practices and effects on symptoms of mental disorders,and expand our discussion to identify three key brain networks associated with mindfulness practices including default mode network,central executive network,and salience network.More research efforts need to be devoted into identifying underlying neuropsychological mechanisms of MM on how it alleviates the symptoms of mental disorders.

Analysis of the Effect of Mindfulness Meditation on Patients with Burning Mouth Syndrome

Objective:To explore the effect of mindfulness meditation on patients with burning mouth syndrome.Methods:60 patients with burning mouth syndrome in our hospital who were treated from January 2021 to December 2022 were selected for this study.The patients were divided into two groups of thirty cases each using the randomized numerical table method.The observation underwent psychological intervention and mindfulness meditation training,while the control group only received symptomatic care.The condition of the patients of both groups was observed and compared.Results:Upon receiving treatment,the patients in the observation group had lower Hamilton Anxiety(HAM-A)scores,and Hamilton Depression(HAMD)scores compared to the control group(P<0.05).The visual analog scale(VAS)scores of the observation group were also lower than those of the control group(P<0.05).Moreover,the efficacy of the nursing intervention in the observation group was higher than that of the control group(P<0.05).Conclusion:Psychological intervention and mindfulness meditation training can effectively improve the clinical symptoms of patients with burning mouth syndrome.Therefore,this treatment method should be popularized.

Effect of Mindful Meditation, Physical Activity, and Diet to Reduce the Risk to Develop or Reduce Severity of Cardiovascular Diseases in Saudi Arabia: A Systematic Review

Background: Cardiovascular Disease (CVD) is one of the leading chronic diseases in Saudi Arabia (SA) that cause disability and death. CVD predisposition risk varies according to age, gender, education, socioeconomic factors, and place of residency. In addition, CVD risk factors include physical inactivity, sedentary lifestyle, saturated fatty acid high diet, smoking, and stress. Aim: This is a systematic review study that aims to determine the effect of mindful mediation, physical activity, and diet on CVD in SA. Materials and Methods: This is a systematic electronic search method in Google scholar, PubMed, and Medline. Papers collected are papers that have been published since 2015. The search uses the following keywords: (Cardiovascular disease OR physical activity OR Physical inactivity OR meditation OR diet) AND Saudi Arabia. Data were extracted from each study through a narrative summary of each study. Results: Forty papers collected from 2015 to 2022 were included in the narrative study. Physical activity, diet, and mindful meditation are among the factors that can reduce the risk of development of CVD or severity of disease in patients with a CVD. Conclusion: This systematic review emphasized risk factors like physical inactivity, poor diet, and low level of awareness among Saudis and CVD Saudi patients. The findings show the role of physical activity, mindful meditation, and diet in reducing the onset or severity of cardiovascular disease.

Improving psychotherapy research： The example of mindfulness based interventions

The increasing number and sophistication of available psychotherapies suggests that a critical appraisal of the methodological issues of psychotherapy studies is highly needed. Several key questions regarding the efficacy of a given intervention, the understanding of whether positive effects observed following the delivery of a psychotherapeutic intervention are specifcally attribut-able to the intervention itself or to other “non specifc” factors, such as beneft expectations, therapist attention and support, and the possibility of improving psycho-therapy research need an answer. This, in turn, could provide clinicians with more rigorous information about psychotherapy outcomes and could properly address several shortcomings that are frequently observed in current psychotherapy studies. Accordingly, in this edi-torial I will highlight some of the most important critical issues that a well designed psychotherapy study should take into account, including the need for appropriate control groups, appropriate randomization and blinding procedures, and the importance of performing appro-priately powered studies that include a suffciently long follow-up period. Finally, I will build on my expertise in the feld of mindfulness based interventions, in particu-lar mindfulness based stress reduction and mindfulness based cognitive therapy, to show how such issues have been and can be successfully implemented in the design of future psychotherapy studies.

Evaluation of facial temperature distribution changes during meditation using infrared thermal imaging:An experimental,cross-over study

Objective:To investigate the differences between meditation and resting states using infrared thermal imaging(IRTI)to determine facial temperature distribution features during meditation and annotate the patterns of facial temperature changes during meditation from the perspective of traditional Chinese medicine facial diagnosis.Methods:Each participant performed 10 min meditation and 10 min resting but in different sequences.A concentration test was set as the task load,followed by a meditation/resting or resting/meditation session,during which the participants'facial temperatures were observed using IRTI.Participants were scored on the Big Five Inventory(BFI)and Mindful Attention Awareness Scale(MAAS).Results:Forehead temperatures decreased more during meditation than during the resting state.The chin temperature increased only during meditation(P<.0001).For the subjects with meditation experience,there were significant differences in the temperatures of the left forehead(P<.01),right forehead(P<.01)and chin(P<.05)between the meditation and resting state at the 10~(th)min.In the nontask state,the BFI-Extraversion showed a negative correlation with the temperature of the left forehead(R=-0.41,P=.03).In the post-task state,the temperature of the left forehead was negatively correlated with scores on the MAAS(R=-0.42,P=.02).Conclusion:Using IRTI to study meditation offers a practical solution to the challenges in meditation research.The results indicate that an increase in chin temperature may be a representative feature of a meditation state,and forehead temperature is also a potential indicator.

Mindfulness-based cognitive therapy in the intervention of psychiatric disorders: A review

Mindfulness-based cognitive therapy(MBCT)is frequently used for psychiatric disorders.Despite MBCT’s considerable potential for improving psychological health for patients,there is little empirical evidence to support its practical application in Chinese.This review will define meditation and mindfulness,provide an overview of the development of MBCT,identify the evidence for the effectiveness of MBCT,and offer recommendations to medical personnels on how to provide support for patients receiving mindfulness intervention.

Contemplative sciences:A future beyond mindfulness

Mindfulness is a psychological technique based on Eastern meditative practices that was developed in the late 1970s by Kabat-Zinn at the University of Massachusetts.Initially,there was a debate over whether it should be considered a scientific technique or labelled as part of the“new wave”practices.Today,mindfulness is omnipresent in modern societies but has suffered from merchandising and banalization,which has been strongly criticized.Despite some limitations regarding methodological aspects of mindfulness research,it is considered effective for treating many physical and psychological disorders,and even it is recommended in clinical guidelines such the British National Institute for Health and Care Excellence.During the last 2500 years,mindfulness practices have moved from Northern India across most of Asia,but their mixing with Western science and culture at the end of the 20^(th)century is considered a key event in recent history.For the first time in human history,due to globalization,the wisdom of all contemplative traditions can be shared with all human beings and assessed by science.Mindfulness practices,yoga included,are giving birth to a new field of knowledge,contemplative sciences,which go beyond mindfulness and is devoted to helping humanity to reach higher levels of happiness and mental peace.

Effects of mindfulness-based interventions on depressive symptoms in patients with substance use disorders:a systematic review and meta-analysis

Objective:We examined the effects of mindfulness-based interventions(MBIs)on depressive symptoms in patients with substance use disorders(SUDs)and explored the moderating effects of participant,method,and intervention characteristics.Methods:We systematically searched 8 databases from their inception till November 2021.The inclusion criteria were primary studies evaluating MBIs in patients with SUDs with depression measured as an outcome,those including a control group,and those written in English.We used a random-effects model to compute effect sizes(ESs)using Hedges’g,a forest plot,and Q and I2 statistics as measures of heterogeneity;we also examined moderator analyses.Results:Nineteen studies included 1352 participants(age:38.6±7.0 years).Overall,MBIs showed significantly improved depression(g=0.67,95%confidence interval[CI]:0.29,1.05,I2=89%)compared to controls.With regard to moderators,providing MBIs as an individual plus group intervention had a greater effect(g=2.13)on reducing depressive symptoms than providing MBIs as a group intervention(g=0.64)or an individual intervention only(g=0.33,P=0.034).Using concealed allocation tended to reduce depressive symptoms(g=1.22)as compared to not using concealed allocation(g=0.48,P=0.086).No other quality indicators were demonstrated to have a moderating influence on the value of the ES.Conclusions:MBIs improved depressive symptoms in patients with SUDs.MBIs might be used as an adjunctive or alternative to conventional treatment for depressed patients with SUDs.

Military-related posttraumatic stress disorder and mindfulness meditation:A systematic review and meta-analysis

Purpose:Posttraumatic stress disorder(PTSD)is a significant global mental health concern,especially in the military.This study aims to estimate the efficacy of mindfulness meditation in the treatment of military-related PTSD,by synthesizing evidences from randomized controlled trials.Methods:Five electronic databases(Pubmed,EBSCO Medline,Embase,PsychINFO and Cochrane Library)were searched for randomized controlled trials focusing on the treatment effect of mindfulness meditation on military-related PTSD.The selection of eligible studies was based on identical inclusion and exclusion criteria.Information about study characteristics,participant characteristics,intervention details,PTSD outcomes,as well as potential adverse effects was extracted from the included studies.Risk of bias of all the included studies was critically assessed using the Cochrane Collaboration's tool.R Statistical software was performed for data analysis.Results:A total of 1902 records were initially identified and screened.After duplicates removal and title&abstract review,finally,19 articles in English language with 1326 participants were included through strict inclusion and exclusion criteria.The results revealed that mindfulness meditation had a significantly larger effect on alleviating military-related PTSD symptoms compared with control conditions,such as treatment as usual,present-centered group therapy and PTSD health education(standardized mean difference(SMD)=-0.33;95%CI[-0.45,-0.21];p<0.0001).Mindfulness interventions with different control conditions(active or non-active control,SMD=-0.33,95%CI[-0.46,-0.19];SMD=-0.49,95%CI[-0.88,-0.10],respectively),formats of delivery(group-based or individual-based,SMD=-0.30,95%CI[-0.42,-0.17],SMD=-0.49,95%CI[-0.90,-0.08],respectively)and intervention durations(short-term or standard duration,SMD=-0.27,95%CI[-0.46,-0.08],SMD=-0.40,95%CI[-0.58,-0.21],respectively)were equally effective in improving military-related PTSD symptoms.Conclusion:Findings from this meta-analysis consolidate the efficacy and feasibility of mindfulness meditation in the treatment of military-related PTSD.Further evidence with higher quality and more rigorous design is needed in the future.

沙氏结肠炎汤联合正念冥想对肝郁脾虚型溃疡性结肠炎的影响

目的:探讨沙氏结肠炎汤联合正念冥想对肝郁脾虚型溃疡性结肠炎(UC)的影响。方法:选取2022年8月—2023年8月启东市中医院收治的87例肝郁脾虚型UC患者作为研究对象。根据随机数表法将其分为观察组(n=44)和对照组(n=43)。对照组给予美沙拉嗪,观察组在对照组基础上给予沙氏结肠炎汤联合正念冥想。比较两组治疗前后中医症候积分、情志、睡眠及疼痛,临床疗效及不良反应。结果:治疗后,两组中医症候积分降低,观察组中医症候积分低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组的医院焦虑抑郁量表(HADS)-A、HDAS-D、数字疼痛评分表(NRS)、匹兹堡睡眠质量指数量表(PSQI)评分均明显低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组临床疗效优于对照组,差异有统计学意义(P<0.05)。两组未观察到不良反应。结论:在美沙拉嗪的基础上加用沙氏结肠炎汤联合正念冥想治疗肝郁脾虚型UC的效果优于单用美沙拉嗪。

结构式团体心理疗法联合正念冥想训练对青少年抑郁症患者希望水平及应对方式的影响

目的探讨结构式团体心理疗法联合正念冥想训练在青少年抑郁症患者中的应用效果.方法选取2021年9月—2023年9月我院收治的82例青少年抑郁症患者为研究对象,按随机数字表法将其分为对照组与观察组,各41例.对照组采用常规干预,观察组采用结构式团体心理疗法联合正念冥想训练干预.对比两组抑郁情绪、希望水平、应对方式及生活质量.结果干预后,观察组汉密尔顿抑郁量表、简易应对方式问卷(SCSQ)中的消极应对评分均低于对照组,Herth希望量表、SCSQ问卷中的积极应对、世界卫生组织生存质量测定量表评分均高于对照组,组间差异有统计学意义(P<0.05).结论结构式团体心理疗法联合正念冥想训练可以减轻青少年抑郁症患者抑郁情绪,提高希望水平,改善应对方式及生活质量.

SHOW模式正念冥想在甲状腺癌术后患者中的应用效果分析

目的探讨SHOW模式正念冥想对甲状腺癌患者术后负性情绪和生活质量的影响,为甲状腺癌术后患者的护理提供科学的参考依据。方法选择2021年1—12月于医院采取甲状腺癌手术治疗的80例患者作为研究对象,按照组间基本特征具有可比性的原则将80例甲状腺癌患者分为观察组40例和对照组40例。对照组患者术后采用常规护理,观察组开展常规术后护理联合SHOW模式下的正念冥想干预,干预时间从患者入院当日至患者出院。患者入院后的1~2 d内填写一般资料调查表、抑郁自评量表(SDS)与焦虑自评量表(SAS)、生命质量测定量表(QLQ-C30)和护理工作满意度调查表,完成首次调查;出院后3个月时患者到医院复查完成术后的问卷调查。评估患者心理状态、生活质量和对护理工作的满意度。结果观察组干预3个月后SDS和SAS评分低于对照组,差异有统计学意义(均P<0.05)。观察组干预3个月后的QLQ-C30总均分及认知功能、情绪功能、角色功能、社会功能和躯体功能评分均高于对照组,差异有统计学意义(P<0.05);观察组患者对护理服务的满意度评分均较对照组患者高,差异有统计学意义(均P<0.05)。结论甲状腺癌手术患者围术期普遍存在焦虑、抑郁情绪,实施后SHOW模式正念冥想护理,利于改善患者心理状态,护理措施更具个性化和针对性,应用于甲状腺癌术后患者中效果良好,利于保持患者良好的心理状态,对于生活质量的改善和提升具有积极意义,患者对护理服务的满意度更高,利于提升临床护理服务水平。

正念冥想训练联合适度有氧运动干预对HDP的效果

目的:探究正念冥想训练联合适度有氧运动干预对妊娠期高血压疾病(HDP)效果。方法:选择2022年1月-2023年6月本院产前检查的HDP患者116例,采用随机数表法分为两组各58例,均常规护理干预,观察组同时给予正念冥想训练联合适度有氧运动干预。记录并比较两组护理前后血压、生活质量综合评定问卷-74(GQOL-74)、抑郁-焦虑和压力量表(DASS)、正念注意觉知量表(MAAS)、护理满意度、不良分娩结局。结果:干预8周后两组各观察指标均有改善,但观察组收缩压(125.4±16.3 mmHg)、舒张压(83.7±10.9 mmHg)、DASS量表均低于对照组[收缩压(137.7±19.3 mmHg)、舒张压(89.4±9.8 mmHg)],生活质量评分、MAAS量表(69.57±11.24分)高于对照组(58.14±12.30分),护理满意度(98.3%)高于对照组(87.9%),不良分娩结局(8.6%)低于对照组(31.0%)(均P>0.05)。结论:正念冥想训练联合适度有氧运动干预用于HDP,可降低患者高血压,改善生活质量和负面情绪,提高正念水平,提升患者护理满意度,减少了不良分娩结局发生。

简易正念冥想对冠心病患者经皮冠脉介入术后负性情绪疗效的随机对照试验

目的:评估正念简易冥想训练对改善冠心病经皮冠状动脉介入治疗(PCI)术后患者负性情绪、正念注意觉知水平及睡眠质量的影响。方法:选心内科收治的冠心病PCI术后患者84例。按照简单随机的原则将其分为干预组42例和对照组42例。分别采用焦虑自评量表/抑郁自评量表、正念注意觉知量表、匹兹堡睡眠质量指数量表作为干预前后评价指标。结果:干预组干预前后的焦虑、抑郁及正念注意觉知总分差值高于对照组(P<0.05);干预前后的睡眠总分及睡眠质量、入睡时间、睡眠时间、催眠药物使用、日间功能障碍及睡眠总分差值均高于对照组(P<0.05)。结论:简易正念冥想训练能够缓解冠心病PCI术后患者不良情绪,提高正念注意觉知,改善患者睡眠质量。

正念冥想训练配合角调音乐疗法干预对老年抑郁症伴失眠患者心境状态与睡眠质量的影响

目的探讨正念冥想训练配合角调音乐疗法干预对老年抑郁症伴失眠患者心境状态与睡眠质量的影响。方法选取2022年1月至2023年6月江西省精神病院收治的81例老年抑郁症伴失眠患者作为研究对象,采用奇偶数分组法进行分组,分为联合组(n=40)和参照组(n=41)。参照组予以常规护理结合角调音乐疗法,联合组在参照组的基础上予以正念冥想训练。两组均持续护理3周,比较两组患者心境状态、睡眠质量、服药依从性和护理满意度。结果联合组症状自评量表(SCL-90)、汉密尔顿焦虑抑郁量表(HADS)、匹兹堡睡眠质量指数量表(PSQI)、Morisky问卷评分均低于参照组,差异有统计学意义(P<0.05)。联合组护理满意度高于参照组,差异有统计学意义(P<0.05)。结论对老年抑郁症伴失眠患者行正念冥想训练配合角调音乐疗法干预能有效改善负性心态与睡眠质量,同时提升服药依从性与护理满意度。