Observation on the Effect of Umbilical Therapy of Herbal Medicine Combined with Self-Made Dysmenorrhea Paste on Primary Dysmenorrhea

Objective:To investigate the clinical effect of self-made dysmenorrhea paste combined with umbilical therapy of herbal medicine on primary dysmenorrhea.Methods:160 patients with primary dysmenorrhea were recruited from Changle People’s Hospital.Participants were randomly divided into control group and treatment group,with 80 cases in each group.The control group were administered the dysmenorrhea paste sold on the market for 5 days during three menstruation cycles,and the treatment group was given the umbilical therapy of herbal medicine combined with self-made dysmenorrhea paste.The outcome was the intensity of menstrual pain measured by using the visual analogue scale,TCM symptom score and dysmenorrhea symptom score of patients,responder rate.The clinical outcomes were measured on each menstrual cycle at baseline,treatment course(3 cycles),and follow-up period.Results:In this study,there was no significant difference in age and severity of disease between the two groups before treatment.After treatment,VAS score,TCM symptom score and dysmenorrhea symptom score of patients in both groups decreased.The total effective rate was 90.75%in the treatment group and 81.25%in the control group.Conclusion:The treatment of primary dysmenorrhea patients with self-made dysmenorrhea paste combined with application of drugs and moxibustion naval-button method has a significant clinical effect.This method can reduce the pain of patients,improve the quality of life of patients,and homemade dysmenorrhea paste has a good taste,long shelf life,easy to carry,and is worthy of promotion and application.

Effect of self-made exhaust plaster on patients with gastrointestinal dysfunction after gynecological operation

Objective:To explore the effect of self-made exhaust patch(SMEP)on gastrointestinal dysfunction after gynecological operation.Methods:A total of 200 patients with gynecological operation in the gynecological ward of Shandong Changle People's Hospital were randomly divided into the control group(n=100)and the treatment group(n=100).The recovery time of bowel sounds,the time of first anal exhaust,the duration of abdominal distention,the duration of abdominal pain,the incidence of abdominal distention and abdominal pain and linical efficacy of SMEP were observed.Results:Compared with the control group,the recovery time of gastrointestinal function and the first anal exhaust time in the treatment group were shorter;the duration of abdominal distention and abdominal pain in the treatment group were shorter than those in the control group(P<0.05);Cure rate of abdominal distention in the treatment is 62.5%and cure rate of abdominal pain in the treatment is 60%within 72 hours after operation,which is higher than that in the control group(44.%,45.9%).Conclusion:The results showed that the self-made exhaust patch can improve the clinical symptoms of patients after gynecological abdominal surgery,and the self-made exhaust patch had a significant effect on gastrointestinal dysfunction after gynecological surgery,which was worthy of clinical promotion.

苗药痛经精油、加热贴对原发性痛经模型大鼠PGF_(2a)、PGE_(2)的影响研究

目的:研究苗药痛经精油、加热贴对原发性痛经(Primary dysmenorrhea,PD)模型大鼠血清及子宫匀浆中前列腺素(包括PGE_(2)、PGF_(2a))表达的影响。方法:采用苯甲酸雌二醇联合缩宫素(OT)建立PD模型大鼠,观察苗药痛经精油、加热贴对痛经大鼠扭体潜伏期和扭体次数的影响;选用酶联免疫吸附法(ELISA法)检测痛经大鼠血清及子宫匀浆中PGE_(2)、PGF_(2a)的浓度变化;应用SPSS 26.0数据分析软件进行数据统计分析。结果:苗药痛经精油、加热贴可延长痛经大鼠的扭体潜伏时间,减少扭体次数,并能影响痛经大鼠血清及子宫匀浆中PGE_(2)、PGF_(2a)的浓度,与各自所对应的组比较,差异有统计学意义(P<0.05或P<0.01)。结论:苗药痛经精油、加热贴治疗痛经大鼠疼痛的内分泌机制可能与升高血清及子宫组织中PGE_(2)浓度、降低血清及子宫组织中PGF_(2a)浓度有关。

自制化瘀止痛贴穴位贴敷联合口服中药治疗原发性痛经的临床疗效分析

目的探讨自制化瘀止痛贴中药穴位贴敷联合少腹逐瘀汤治疗血瘀型原发性痛经的效果。方法选择2021年5月—2022年9月梅州市中医医院收治的60例血瘀型原发性痛经患者为研究对象,采用随机数表法分为两组,每组30例。对照组采取少腹逐瘀汤治疗,观察组在对照组基础上加自制化瘀止痛贴贴敷治疗,比较两组治疗效果。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前,两组CMSS评分对比,差异无统计学意义(P>0.05),治疗后,观察组CMSS评分低于对照组,差异有统计学意义(P<0.05)。6个月后随访,观察组复发率为3.45%低于对照组的29.17%,差异有统计学意义(χ^(2)=4.919,P<0.05)。结论自制化瘀止痛贴中药穴位贴敷联合中药辨证口服治疗血瘀型原发性痛经的效果显著,可以改善患者痛经症状,减轻疼痛程度,也能减少复发。

三伏贴联合督脉灸治疗寒凝血瘀型痛经临床疗效观察

[目的]观察三伏贴联合督脉灸治疗寒凝血瘀型痛经的临床疗效。[方法]通过临床病例选择80例痛经患者,辨证分型为寒凝血瘀型,随机数字表法分为治疗组和对照组。治疗组采用三伏贴联合督脉灸治疗,对照组口服益母草颗粒,观察其临床疗效。[结果]治疗组40例寒凝血瘀型痛经患者,治愈10例,显效18例,有效10例,无效2例,总有效率95%。对照组40例患者,治愈4例,显效8例,有效15例,无效13例,总有效率67.5%。两组比较差异具有统计学意义(P<0.05),表明治疗组三伏贴联合督脉灸疗效优于对照组药物。两组患者治疗前后积分比较,差异具有统计学意义(P<0.05),表明三伏贴联合督脉灸及药物疗法对痛经均有疗效。两组比较,治疗组疗效优于对照组药物治疗(P<0.05)。[结论]三伏贴联合督脉灸治疗寒凝血瘀型痛经临床疗效确切,简便安全,费用低廉,符合中医"治未病"理念,值得大力推广。

HPLC法同时测定痛经贴剂中柚皮苷、橙皮苷和新橙皮苷的含量

目的建立HPLC法同时测定痛经贴剂中柚皮苷、橙皮苷和新橙皮苷的含量。方法采用高效液相色谱法,以CosmosilC18为色谱柱(5μm,4.6 mm×250 mm);乙腈—0.1%磷酸(21∶79)为流动相;流速为1.0 m L·min^(-1);检测波长为283 nm;柱温为25℃;进样量为10μL。结果柚皮苷浓度在10.63~340 mg·L^(-1),橙皮苷浓度在7.81~250 mg·L^(-1),新橙皮苷浓度在8.13~260 mg·L^(-1)范围内线性关系良好,平均加样回收率分别为98.01%、97.90%和98.60%。结论该方法简单、准确、可靠,可用于痛经贴剂的质量控制。

艾灸联合自拟痛经贴对寒凝血瘀型痛经患者疼痛程度及睡眠质量的影响

目的探讨艾灸联合自拟痛经贴对寒凝血瘀型痛经患者疼痛程度及睡眠质量的影响。方法选取2017年3月至2019年2月在徐州市中医院接受治疗的120例寒凝血瘀型痛经患者作为研究对象,根据随机数字表法将其分为观察组与对照组,每组各60例。对照组患者进行常规药物治疗,观察组使用艾灸联合自拟痛经贴进行治疗。比较两组患者的疼痛程度、临床症状及睡眠质量。结果治疗后,两组患者的视觉模拟评分法(VAS)评分低于治疗前,且观察组患者的VAS评分低于对照组,差异有统计学意义(P<0.05)。治疗后,两组患者的痛经持续时间评分、严重程度评分低于治疗前,且观察组患者的痛经持续时间评分、严重程度评分低于对照组,差异有统计学意义(P<0.05)。治疗后,两组患者的匹兹堡睡眠质量指数量表(PSQI)评分低于治疗前,且观察组患者的PSQI评分低于对照组,差异有统计学意义(P<0.05)。结论将艾灸联合自拟痛经贴应用于寒凝血瘀型痛经患者的临床治疗中能够有效缩短症状持续时间,降低严重程度,有利于减少疼痛与提高睡眠质量。

远红外痛经理疗贴治疗妇科疾病120例的临床观察

目的:观察远红外痛经理疗贴治疗妇科痛经、月经不调的临床效疗。方法:回顾性分析本院收治的120例痛经、月经不调患者的临床资料。结果:远红外痛经理疗贴治疗痛经、月经不调有效率分别达到93.33%、96.67%。结论:远红外痛经理疗贴治疗痛经、月经不调妇科疾病疗效确切,且临床使用方便。