Clinical therapeutic effect of self-prescribed Sanhanchushi Tongbi on lumbar disc herniation

BACKGROUND Lumbar disc herniation(LDH)commonly occurs during spinal surgery;LDH is on the increase in younger patients and is classified as"paralysis"and"back pain."Sanhanchushi Tongbi(SPST)is a customized prescription.It disperses cold,relieves pain,removes cold from the meridians and viscera,and treats neuropathic pain.However,few studies have investigated its mechanism of pain relief.AIM To observe the clinical therapeutic effects on LDH treated with self-prescribed SPST.METHODS A total of 211 patients with LDH syndrome were divided into two groups:107 patients in the control group were treated with conventional massage combined with traction,and 104 patients in the observation group were treated with a combination of the control regimen and self-prescribed oral SPST.The patients were treated for 4 wk.Indices of traditional Chinese medicine(TCM)syndrome score and serum inflammatory factor levels were measured.RESULTS After therapy,the TCM syndrome score in the observation group was significantly lower than that in the control group(P<0.05).The main symptoms,clinical signs,daily activities,and Japanese Orthopedic Association scores in the observation group were significantly higher than those in the control group after therapy(P<0.05).The levels of tumor necrosis factor-α,interleukin-6,and C-reactive protein were lower in the observation group than in the control group(P<0.05).In the observation group,superoxide dismutase levels were significantly higher,whereas malondialdehyde levels were significantly lower,compared with the control group(P<0.05).The overall efficacy rate in the observation group was 96.15%,which was substantially higher than that in the control group(88.79%;P<0.05).CONCLUSION Self-prescribed SPST can reduce the levels of inflammatory and pain-causing factors as well as lumbar pain in patients with LDH.

自拟清胞饮联合去氧孕烯炔雌醇片治疗流产后气滞血瘀型宫内组织残留的临床研究

目的:探究自拟清胞饮联合去氧孕烯炔雌醇片治疗流产后气滞血瘀型宫内组织残留的临床疗效。方法:将2021年7月—2023年3月三明市中西结合医院妇科门诊的80例各类流产后宫内组织残留且不愿意清宫患者,根据随机数字表法分为对照组40例与观察组40例。对照组采用去氧孕烯炔雌醇片治疗,观察组则在对照组的基础上加用自拟清胞饮进行治疗。比较两组的治疗效果、阴道出血时间、月经复潮时间、血人绒毛膜促性腺激素(hCG)恢复正常时间、宫内残留组织直径、炎症指标[血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)及白介素-6(IL-6)]及子宫血流指标(螺旋动脉血流参数、子宫底蜕膜血流信号)。结果:观察组的治疗总有效率显著高于对照组,阴道出血时间、月经复潮时间及血hCG恢复正常时间均显著短于对照组(P<0.05)。治疗前,两组的宫内残留组织直径、炎症反应及子宫血流指标比较,差异均无统计学意义(P>0.05);治疗后,观察组的宫内残留组织直径显著小于对照组,炎症反应指标及螺旋动脉峰值舒张期血流速度(PDV)均显著低于对照组,螺旋动脉阻力指数(RI)显著高于对照组,子宫底蜕膜血流信号显著优于对照组(P<0.05)。结论:自拟清胞饮联合去氧孕烯炔雌醇片治疗宫内组织残留临床疗效较好,可显著缩短阴道出血时间及血hCG恢复正常时间,更快促进月经来潮,对于炎症及子宫血流指标也有较好的改善作用。

清胞饮对宫颈上皮内瘤样病变术后患者妊娠结局的影响

目的探讨清胞饮辅助治疗对子宫颈上皮内瘤样病变(CIN)行宫颈环切术(LEEP)后患者妊娠结局的影响。方法将宫颈内瘤样病变行LEEP术后的162例妇女分为治疗组和对照组各81例,治疗组术后应用清胞饮和复方黄柏液治疗,对照组术后应用复方黄柏液治疗,比较2组妊娠结局。结果治疗组治愈率98%,对照组治愈率80%,2组用药后HPV持续阳性、治愈率比较有显著性差异(P均<0.05)。2组足月阴道分娩数、剖宫产率比较均无显著性差异。治疗组阴道分娩的产程较对照组短(P<0.05),无新生儿窒息,无宫颈功能不全者。结论宫颈CIN行LEEP术后辅以清胞饮治疗,治愈率高,复发率低,不良反应少,对要求保留生育功能的患者是安全有效的方法,且不影响其分娩结局。