Numerical simulation of drop weight impact sensitivity evaluation criteria for pressed PBXs

A thorough understanding of drop-weight impacted responses for polymer-bonded explosives(PBXs)is significant to evaluate their impact sensitivity.The characteristics of the drop-weight impacted pressed PBXs including deforming,fracturing,forming a local high-temperature region and igniting,were simulated using a coupled mechanical-thermo-chemical model integrating micro-defects evolution.A novel evaluation method for impact sensitivity is established using the relation between the input kinetic energy and the output energy due to deformation,crushing energy,local hot spot energy and ignition.The effects of impact velocity on sensitivity were analyzed and the critical local ignition impact velocity is determined as 4.0-4.5 m/s.The simulated results show that shear-crack friction heating is the dominant ignition mechanism.The region along the boundary of PBXs sample is the most hazardous regions where ignition first occur.The propagation of stress wave in PBXs causes shear-crack hotspot and bulk temperature exhibiting an approximate 45°direction evolution path,which is the main reason that dominated damage-ignition region transits from the boundary to the central of sample.

Evaluation of the Sensitivity and Specificity of the New Clinical Diagnostic and Classification Criteria for Kashin-Beck Disease,an Endemic Osteoarthritis,in China

This study aimed to evaluate the sensitivity and specificity of the new clinical diagnostic and classification criteria for Kashin-Beck disease （KBD） using six clinical markers： flexion of the distal part of fingers, deformed fingers, enlarged finger joints, shortened fingers, squat down, and dwarfism. One-third of the total population in Linyou County was sampled by stratified random sampling.

The Application of Sensitivity Analysis on Comprehensive Transportation Evaluation

Comprehensive transportation evaluation objects using multi-objective decision method is a process of choosing the best one from a few objects through calculating, analyzing, and comparing the index system. The result may be different because of the difference of the index weight and index value. Therefore, sensitivity analysis should be one of the necessary parts of the decision-making. It is desired to give the index with higher sensitivity and its varying scope to control the index strictly during the execution process. This paper derives transfer index weight, which changes the rank evaluation order of the projects. Meanwhile, a simple, effective and practical method based on sensitivity district and sensitivity matrix is proposed for the sensitivity analysis of decision-making. As an example, the index sensitivity in decision-making of some provinces comprehensive transportation objects, and their influence on the final decision are discussed.

Sensitive Evaluation on Early Cracking Tendency of Concrete with Inclusion of Light-burnt MgO

The advanced temperature and stress test machine was introduced to determine the early cracking tendency of concrete with inclusion of light-burnt MgO under full restraint by tracking the development of thermal,physical and deformation properties.Results showed that light-burnt MgO being incorporated ranging between 4 wt% and 6 wt% of cementitious materials was beneficial to increase the maximum compressive stress and cracking stress of concrete by 0.37 MPa and 0.2 MPa on average respectively.The second zero stress temperature was reduced by 11.4 ℃ and the maximum temperature was slightly reduced while cracking thermal impact was significantly enhanced from 59.8 ℃ to 66.2 ℃.Sensitive anti-cracking coefficient F was forwarded to assess the early cracking tendency of concrete and the inclusion of 4 wt% light-burnt MgO with activity of 109 s ranked the best in crack resistance.

Quality control and evaluation of human immunodeficiency virus antibody assays used for screening donated blood in China

During 2004, a total of 124 batches of HIV antibody ELISAs from domestic and overseas manufacturers, comprising approximately 60 million tests, were tested for quality and released for screening blood in China. The inter- and intra-batch variation, specificity, and sensitivity were evaluated using a laboratory panel and clinical samples. The inter-batch variation was less than 15% and only 2 of 12 assays had intra-bateh variation of less than 20% for 4 dilutions of a control specimen. 257 samples confirmed positive for HIV antibody and 4826 negative samples from different regions in China were used to evaluate the sensitivity and specificity of the assays. The results showed that the sensitivity is in the range from 93.7% to 100% for assays sampled directly from the manufacturers, and 91.4%-99.6% for those retrieved from the consumers; the specificity was in the range from 97.88 % to 99.97 %. The testing environment may vary in different regions of China. Therefore, manufaeturers should provide robust assays to satisfy the requirements of these diverse environments, and especially reduce the intra-assay variation and improve the stability of the kits.