173 simultaneous determinations of serum copper levels (SCL), serum zinc levels (SZL) and copper/zinc ratio (CZR) were made by atomic absorption spectrophotometry in 51 previously untreated lymphoma patients. SCL and ...173 simultaneous determinations of serum copper levels (SCL), serum zinc levels (SZL) and copper/zinc ratio (CZR) were made by atomic absorption spectrophotometry in 51 previously untreated lymphoma patients. SCL and CZR were significantly higher in patients before treatment (mean value 22.97 μmol/L, 1.55, respectively) and in those who did not reach complete remission (mean 21.21 μmol/L, 1.36) as compared with the patients in complete remission (mean 16.36 μmol/L, 1.06) or normal controls (mean 15.67 μmol/L, 0.98). The mean value of SCL and CZR of patients in complete remission did not differ significantly from those of normal controls. Patients in stages HI and IV had higher SCL and CZR (mean 25.15 μmol/L, 1.79) than those in stage Ⅰ and Ⅱ (mean 19.30 μmol/L, 1.16). No significant difference in SZL was observed between the patient groups and normal controls. Thus, SCL and CZR may be used as prognostic indicators for monitoring disease activity and response to therapy in malignant lymphoma.展开更多
为了探讨饲粮铜添加水平对育成前期水貂生长发育及血液生化指标的影响。试验以蛋氨酸螯合铜为铜源,在7组(每组10只)86日龄雄性美国短毛黑水貂基础饲粮(含铜26.68mg/kg)中添加不同水平的铜(0、210、220、230、240、250、300mg/kg)组成水...为了探讨饲粮铜添加水平对育成前期水貂生长发育及血液生化指标的影响。试验以蛋氨酸螯合铜为铜源,在7组(每组10只)86日龄雄性美国短毛黑水貂基础饲粮(含铜26.68mg/kg)中添加不同水平的铜(0、210、220、230、240、250、300mg/kg)组成水貂饲粮,进行60天的饲养试验和消化代谢试验,通过对平均日增重(Average Daily Gain,ADG)、料重比(Feed/Gain,F/G)、脂肪消化率(Fat Digestibility,FD)、氮消化率(Nitrogen Digestibility,ND)、净蛋白质利用率(Net Protein Utilization,NPU)、氮生物学价值(Biological Value of Protein,BV)和血清碱性磷酸酶(Alkaline Phosphate,AKP)、碱性磷酸酶(AlkalinePhosphatase,ALP)、铜蓝蛋白(Ceruloplasmin,CER)、谷丙转氨酶(Alanine Aminotransferase,ALT)、Cu-Zu-SOD指标的测定分析。结果表明:当基础饲粮中铜添加量为210～240mg/kg时,平均日增重和血液生化指标呈升高趋势,在240mg/kg时,体增重最快,平均日增重最高为17.50g/d(P<0.05),超过240mg/kg时,平均日增重和血液生化指标呈降低趋势。以蛋氨酸螯合铜为铜源,在86～146日龄雄性美国短毛黑水貂基础饲粮(含铜26.68mg/kg)中铜的添加量为210～240mg/kg,可明显促进水貂的生长发育和血清酶活性,以240mg/kg时,体增重和平均日增重最高(P<0.05);超过240mg/kg可明显抑制水貂的生长发育和血清酶活性。展开更多
文摘173 simultaneous determinations of serum copper levels (SCL), serum zinc levels (SZL) and copper/zinc ratio (CZR) were made by atomic absorption spectrophotometry in 51 previously untreated lymphoma patients. SCL and CZR were significantly higher in patients before treatment (mean value 22.97 μmol/L, 1.55, respectively) and in those who did not reach complete remission (mean 21.21 μmol/L, 1.36) as compared with the patients in complete remission (mean 16.36 μmol/L, 1.06) or normal controls (mean 15.67 μmol/L, 0.98). The mean value of SCL and CZR of patients in complete remission did not differ significantly from those of normal controls. Patients in stages HI and IV had higher SCL and CZR (mean 25.15 μmol/L, 1.79) than those in stage Ⅰ and Ⅱ (mean 19.30 μmol/L, 1.16). No significant difference in SZL was observed between the patient groups and normal controls. Thus, SCL and CZR may be used as prognostic indicators for monitoring disease activity and response to therapy in malignant lymphoma.
文摘为了探讨饲粮铜添加水平对育成前期水貂生长发育及血液生化指标的影响。试验以蛋氨酸螯合铜为铜源,在7组(每组10只)86日龄雄性美国短毛黑水貂基础饲粮(含铜26.68mg/kg)中添加不同水平的铜(0、210、220、230、240、250、300mg/kg)组成水貂饲粮,进行60天的饲养试验和消化代谢试验,通过对平均日增重(Average Daily Gain,ADG)、料重比(Feed/Gain,F/G)、脂肪消化率(Fat Digestibility,FD)、氮消化率(Nitrogen Digestibility,ND)、净蛋白质利用率(Net Protein Utilization,NPU)、氮生物学价值(Biological Value of Protein,BV)和血清碱性磷酸酶(Alkaline Phosphate,AKP)、碱性磷酸酶(AlkalinePhosphatase,ALP)、铜蓝蛋白(Ceruloplasmin,CER)、谷丙转氨酶(Alanine Aminotransferase,ALT)、Cu-Zu-SOD指标的测定分析。结果表明:当基础饲粮中铜添加量为210～240mg/kg时,平均日增重和血液生化指标呈升高趋势,在240mg/kg时,体增重最快,平均日增重最高为17.50g/d(P<0.05),超过240mg/kg时,平均日增重和血液生化指标呈降低趋势。以蛋氨酸螯合铜为铜源,在86～146日龄雄性美国短毛黑水貂基础饲粮(含铜26.68mg/kg)中铜的添加量为210～240mg/kg,可明显促进水貂的生长发育和血清酶活性,以240mg/kg时,体增重和平均日增重最高(P<0.05);超过240mg/kg可明显抑制水貂的生长发育和血清酶活性。
