Studies on the Synthesis of Sesamin-Group Lignans Ⅷ. A Simplified Sythesis of 2-Aryl-4-phenyloxazoles and 2-Alkyl-4-phenyloxazoles

The reaction of phenacyl benzoate derivatives with acetamide at about 140°in the presence of BF3 catalyst gave 2-aryl-4-phenyloxazoles. This method can be applied to the preparation of 2-alkyl-4-phenyloxazoles as well.

芝麻素类型木脂素类似物的研究Ⅰ.2-芳基四氢呋喃的合成

本文根据芝麻素类型木脂素化合物的结构共同点,认为其具有生理活性的基本结构可能是其分子所含的2-芳基四氢呋喃结构。因此,按照Topliss的药物系统设计法,合成了6个在芳环上含有不同取代基的2-芳基四氢呋喃。