Continued innovation in screening methodologies remains important for the discovery of high-quality multiactive fungi,which have been of great significance to the development of new drugs.Mangrove-derived fungi,which ...Continued innovation in screening methodologies remains important for the discovery of high-quality multiactive fungi,which have been of great significance to the development of new drugs.Mangrove-derived fungi,which are well recognized as prolific sources of natural products,are worth sustained attention and further study.In this study,118 fungi,which mainly included Aspergillus spp.(34.62%)and Penicillium spp.(15.38%),were isolated from the mangrove ecosystem of the Maowei Sea,and 83.1%of the cultured fungi showed at least one bioactivity in four antibacterial and three antioxidant assays.To accurately evaluate the fungal bioactivities,the fungi with multiple bioactivities were successfully evaluated and screened by principal component analysis(PCA),and this analysis provided a dataset for comparing and selecting multibioactive fungi.Among the 118 mangrove-derived fungi tested in this study,Aspergillus spp.showed the best comprehensive activity.Fungi such as A.clavatonanicus,A.flavipes and A.citrinoterreus,which exhibited high comprehensive bioactivity as determined by the PCA,have great potential in the exploitation of natural products and the development of new drugs.This study demonstrated the first use of PCA as a time-saving,scientific method with a strong ability to evaluate and screen multiactive fungi,which indicated that this method can affect the discovery and development of new drugs.展开更多
This paper is the first recorded economic value of living fossil,an evaluation of the basic economic value of Lingula,based on the direct utilization of households for food and sale.Twenty-one local fishermen who coll...This paper is the first recorded economic value of living fossil,an evaluation of the basic economic value of Lingula,based on the direct utilization of households for food and sale.Twenty-one local fishermen who collected Lingula in Trat Province were focused on by using interview questionnaires.The animal habitats are influenced by the encroachers'age,gender and harvest method.The total economic value in 2011 was around two million baht.Those who possess fishing gear and have more money can have greater access to the product The local communities in Nong Khunsong sub-district are successful in collecting the Lingula and in doing local business.The market channel analysis is conducted at local,provincial and national levels and short market chains are demonstrated in the form of a wholesale market in the Lingula trade.This represents significant consumption by the local communities.The study further recommends sustainable conservation and management efforts at a local scale.展开更多
基金the Key R&D Program of Shandong Province(No.2020CXGC010703)the Key Project of the Natural Science Foundation of Shandong Province(No.ZR2020 KB021)。
文摘Continued innovation in screening methodologies remains important for the discovery of high-quality multiactive fungi,which have been of great significance to the development of new drugs.Mangrove-derived fungi,which are well recognized as prolific sources of natural products,are worth sustained attention and further study.In this study,118 fungi,which mainly included Aspergillus spp.(34.62%)and Penicillium spp.(15.38%),were isolated from the mangrove ecosystem of the Maowei Sea,and 83.1%of the cultured fungi showed at least one bioactivity in four antibacterial and three antioxidant assays.To accurately evaluate the fungal bioactivities,the fungi with multiple bioactivities were successfully evaluated and screened by principal component analysis(PCA),and this analysis provided a dataset for comparing and selecting multibioactive fungi.Among the 118 mangrove-derived fungi tested in this study,Aspergillus spp.showed the best comprehensive activity.Fungi such as A.clavatonanicus,A.flavipes and A.citrinoterreus,which exhibited high comprehensive bioactivity as determined by the PCA,have great potential in the exploitation of natural products and the development of new drugs.This study demonstrated the first use of PCA as a time-saving,scientific method with a strong ability to evaluate and screen multiactive fungi,which indicated that this method can affect the discovery and development of new drugs.
基金support in the project "The Studies of Population Status in Lamp shell (Brachiopoda:Lingulidea) at mangrove habitat in Thailand." supported by KURDI,Kasetsart University
文摘This paper is the first recorded economic value of living fossil,an evaluation of the basic economic value of Lingula,based on the direct utilization of households for food and sale.Twenty-one local fishermen who collected Lingula in Trat Province were focused on by using interview questionnaires.The animal habitats are influenced by the encroachers'age,gender and harvest method.The total economic value in 2011 was around two million baht.Those who possess fishing gear and have more money can have greater access to the product The local communities in Nong Khunsong sub-district are successful in collecting the Lingula and in doing local business.The market channel analysis is conducted at local,provincial and national levels and short market chains are demonstrated in the form of a wholesale market in the Lingula trade.This represents significant consumption by the local communities.The study further recommends sustainable conservation and management efforts at a local scale.
