Hello,My name is Li Shiyun.I have a good friend.Her name is Wu Jiayi. Wu Jiayi in really tall.And she is beautiful too.She has long hair and big black eyes.She likes singing songs.She is very hard-working at school.At...Hello,My name is Li Shiyun.I have a good friend.Her name is Wu Jiayi. Wu Jiayi in really tall.And she is beautiful too.She has long hair and big black eyes.She likes singing songs.She is very hard-working at school.At home, she is helpful. She washes socks for her father and washes dishes after dinner.展开更多
目的:系统评价经方辨证对比抗组胺药治疗湿疹的有效性和安全性。方法:计算机检索中国生物医学文献光盘数据库、中国期刊全文数据库,收集经方辨证(试验组)对比抗组胺药(对照组)治疗湿疹的随机对照试验(RCT)。筛选文献、提取资料后采用改...目的:系统评价经方辨证对比抗组胺药治疗湿疹的有效性和安全性。方法:计算机检索中国生物医学文献光盘数据库、中国期刊全文数据库,收集经方辨证(试验组)对比抗组胺药(对照组)治疗湿疹的随机对照试验(RCT)。筛选文献、提取资料后采用改良Jadad量表对纳入文献质量进行评价,采用Rev Man 5.3软件进行Meta分析。结果:共纳入19项RCT,共计1829例患者。Meta分析结果显示,试验组湿热蕴肤型[OR=5.67,95%CI(3.44,9.33),P<0.00001]、脾虚湿蕴型[OR=4.23,95%CI(1.89,9.46),P=0.0004]、血虚风燥型[OR=3.57,95%CI(2.36,5.41),P<0.00001]患者总有效率均显著高于对照组。试验组湿热蕴肤型[OR=0.72,95%CI(0.21,2.41),P=0.59]、脾虚湿蕴型[OR=0.31,95%CI(0.01,13.57),P=0.54]、血虚风燥型[OR=1.08,95%CI(0.18,6.59),P=0.93]患者不良反应发生率与对照组比较,差异均无统计学意义。治疗后,试验组湿热蕴肤型患者肿瘤坏死因子α[SMD=-1.67,95%CI(-2.04,-1.31),P<0.00001]、白细胞介素6[SMD=-1.53,95%CI(-1.88,-1.17),P<0.00001]、白细胞介素8[SMD=-1.75,95%CI(-2.28,-1.21),P<0.00001]水平均显著低于对照组;CD4+水平[SMD=1.51,95%CI(-0.37,3.38),P=0.12]与对照组比较,差异无统计学意义。结论:经方辨证治疗湿疹的效果显著优于抗组胺药治疗,且安全性相当;龙胆泻肝汤加减可显著降低湿热蕴肤型患者的炎症因子水平。展开更多
文摘Hello,My name is Li Shiyun.I have a good friend.Her name is Wu Jiayi. Wu Jiayi in really tall.And she is beautiful too.She has long hair and big black eyes.She likes singing songs.She is very hard-working at school.At home, she is helpful. She washes socks for her father and washes dishes after dinner.
文摘目的:系统评价经方辨证对比抗组胺药治疗湿疹的有效性和安全性。方法:计算机检索中国生物医学文献光盘数据库、中国期刊全文数据库,收集经方辨证(试验组)对比抗组胺药(对照组)治疗湿疹的随机对照试验(RCT)。筛选文献、提取资料后采用改良Jadad量表对纳入文献质量进行评价,采用Rev Man 5.3软件进行Meta分析。结果:共纳入19项RCT,共计1829例患者。Meta分析结果显示,试验组湿热蕴肤型[OR=5.67,95%CI(3.44,9.33),P<0.00001]、脾虚湿蕴型[OR=4.23,95%CI(1.89,9.46),P=0.0004]、血虚风燥型[OR=3.57,95%CI(2.36,5.41),P<0.00001]患者总有效率均显著高于对照组。试验组湿热蕴肤型[OR=0.72,95%CI(0.21,2.41),P=0.59]、脾虚湿蕴型[OR=0.31,95%CI(0.01,13.57),P=0.54]、血虚风燥型[OR=1.08,95%CI(0.18,6.59),P=0.93]患者不良反应发生率与对照组比较,差异均无统计学意义。治疗后,试验组湿热蕴肤型患者肿瘤坏死因子α[SMD=-1.67,95%CI(-2.04,-1.31),P<0.00001]、白细胞介素6[SMD=-1.53,95%CI(-1.88,-1.17),P<0.00001]、白细胞介素8[SMD=-1.75,95%CI(-2.28,-1.21),P<0.00001]水平均显著低于对照组;CD4+水平[SMD=1.51,95%CI(-0.37,3.38),P=0.12]与对照组比较,差异无统计学意义。结论:经方辨证治疗湿疹的效果显著优于抗组胺药治疗,且安全性相当;龙胆泻肝汤加减可显著降低湿热蕴肤型患者的炎症因子水平。
