Shock-wave impact on the knee joint affected with osteoarthritis and after arthroplasty

Degenerative diseases significantly reduce the quality of human life.Non-invasive treatments are used in the initial stages of osteoarthritis(OA).Total knee arthroplasty is used in the late stages of osteoarthritis of the knee joint.Non-invasive methods based on mechanical action are also used for the rehabilitation of a patient after arthroplasty.This paper presents numerical models of the knee joint with degenerative OA changes and arthroplasty.Using these models,a computational study was made of the influence of the intensity of shock-wave exposure on the conditioning for the regeneration of bone and cartilage tissues.Based on the modeling results,it was found that in the knee joint with degenerative OA changes,conditions for the regeneration of cartilage and meniscus tissues were fulfilled under medium and highintensity loading.Under high-intensity loading(up to 0.9 m J/mm^(2)),the stress level was significantly below the ultimate value required for fracture.At knee arthroplasty,the conditions for bone tissue regeneration around the tibia component are fulfilled only under high-intensity loading.

Numerical Simulation of Two-Dimensional Shock/Boundary-Layer Interaction between a Rocket and Booster

A two-dimensional Reynolds-averaged Navier-Stokes solver is applied to analyze the aerodynamic behavior of the Shock/Boundary-Layer interaction of rocket with a boosted The K-ε turbulence model and a finite volume method in a unstructured body-fitted curvilinear coordinates have been used. The results indicate that the separation and the reattachment occur in the Boundary-Layer of the main rocket because of the shock interaction. The shape of the booster nose effects the flow field obviously. In the case of the hemisphere booster nose the pressure has complicate distributions and the separation is very clear. The distance between the booster and main rocket has the evident effect on the flow field. If the distance is smaller the pressure coefficient is bigger the separation zone even the separation bubble occurs.

Boundary-layer receptivity under interaction of free-stream turbulence and localized wall roughness

The boundary-layer receptivity under the interaction of free-stream turbu- lence （FST） and localized wall roughness is studied by the direct numerical simulation （DNS） and the fast Fourier transform. The results show that the Tollmien-Schlichting （T-S） wave packets superposed by a group of stability, neutral, and instability T-S waves are generated in the boundary layer. The propagation speeds of the T-S wave packets are calculated. The relation among the boundary-layer receptivity response, the amplitude of the FST, the roughness height, and the roughness width is determined. The results agree well with Dietz＇s experiments. The effect of the roughness geometries on the receptivity is also studied.

Boundary-Layer Wind Structure in a Landfalling Tropical Cyclone

In this study, a slab boundary layer model with a constant depth is used to analyze the boundary-layer wind structure in a landfalling tropical cyclone. Asymmetry is found in both the tangential and radial components of horizontal wind in the tropical cyclone boundary layer at landfall. For a steady tropical cyclone on a straight coastline at landfall, the magnitude of the radial component is greater in the offshoreflow side and the tangential component is greater over the sea, slightly offshore, therefore the greater total wind speed occurs in the offshore-flow side over the sea. The budget analysis suggests that： （1） a greater surface friction over land produces a greater inflow and the nonlinear effect advects the maximum inflow downstream, and （2） a smaller surface friction over the sea makes the decrease of the tangential wind component less than that over land. Moreover, the boundary layer wind structures in a tropical cyclone are related to the locations of the tropical cyclone relative to the coastline due to the different surface frictions. During tropical cyclone landfall, the impact of rough terrain on the cyclone increases, so the magnitude of the radial component of wind speed increases in the offshore-flow side and the tangential component outside the radius of maximum wind speed decreases gradually.

Distribution Regularity of Muzzle Shock-Wave Inside Protective Cover

The injury of gunners caused by muzzle shock-wave has always been a great problem when firing inside the protective cover. The distribution regularity and personnel injury from the muzzle blast-wave were investigated by both test and numerical simulation. Through the inside firing test, the changes of overpressure and noise have been measured at different measuring points in the thin-wall cover structure with different open widths and shallow covering thickness. The distribution regularity of muzzle shock-wave with different firing port widths is calculated by ANSYS/LSDYNA software. The overpressure distribution curves of muzzle shock-wave inside the structure can be obtained by comparing the test results with the numerical results. Then, the influence of open width and shallow covering thickness is proposed to give a reference to the protective design under the condition of the inside firing with the same cannon caliber.

Series Solution of Non-Similarity Boundary-Layer Flow in Porous Medium

This paper aims to present complete series solution of non-similarity boundary-layer flow of an incompressible viscous fluid over a porous wedge. The corresponding nonlinear partial differential equations are solved analytically by means of the homotopy analysis method (HAM). An auxiliary parameter is introduced to ensure the convergence of solution series. As a result, series solutions valid for all physical parameters in the whole domain are given. Then, the effects of physical parameters γ and Prandtl number Pr on the local Nusselt number and momentum thickness are investigated. To the best of our knowledge, it is the first time that the series solutions of this kind of non-similarity boundary-layer flows are reported.

Quantum Electrostatic Shock-Waves in Symmetric Pair-Plasmas

In this paper, the quantum hydrodynamics (QHD) model is used to study the propagation of small- but finite-amplitude quantum electrostatic shock-wave in an inertial-less symmetric pair (ion) plasma with immobile background positive constituents. The dispersion due to the quantum tunneling and inertial effects as well as dissipation caused by particle collisions leading to the shock-like or double-layer structures are considered. Investigation of both the stationary and traveling-wave solutions to Kortewege-de Veries-Burgers evolution equation show that critical values exist which govern the type of collective plasma structures. Current analysis apply to diverse kind of symmetric plasmas such as laboratory inertially confined or astrophysical pair-ion or electron-positron degenerate plasmas.

Controlling secondary flow in high-lift low-pressure turbine using boundary-layer slot suction

The design of high-lift Low-Pressure Turbines(LPTs)causes the separation of the boundary layer on the suction side of the blade and leads to a strong secondary flow.This present study aims to minimize secondary losses through endwall slot suction and incoming wakes in a front-loaded high-lift LPT cascade with Zweifel of 1.58 under low Reynolds number of 25000.Two slotted schemes for the boundary layer of the endwall were designed(Plan A and Plan B),and the effects of suction mass flow on secondary flow were studied.The underlying physics of the endwall boundary layer of the suction and secondary flow under unsteady wakes was discussed.The results show that slot suction at the endwall boundary layer can significantly suppress the secondary flow by removing low-momentum fluids.Plans A and B significantly reduced the secondary kinetic energy by 44.2%and 36.9%,respectively,compared with the baseline cascade at the suction mass flow ratios of 1%.With an increase in the mass flow ratio of suction,the secondary flow was gradually reduced in both Plans A and B.It is more beneficial to control the secondary flow to destroy the intersection of the pressure side and suction side of the horseshoe vortex before it develops into a passage vortex.Under unsteady wakes,the combined effects of incoming wakes and endwall boundary layer suction can further suppress the secondary flow at the suction mass flow ratios of 2%for Plan A,because the positive and negative vorticity inside upstream wakes accelerated the mixing of the main flow and secondary flow and thus increased the energy of secondary vortices.

Experimental and Numerical Investigations of Shock-Wave Boundary Layer Interactions in a Highly Loaded Transonic Compressor Cascade

Experimental and numerical investigations were conducted to investigate the variations of shock-wave boundary layer interaction(SBLI) phenomena in a highly loaded transonic compressor cascade with Mach numbers.The schlieren technique was used to observe the shock structure in the cascade and the pressure tap method to measure the pressure distribution on the blade surface.The unsteady pressure distribution on blade surface was measured with the fast-response pressure-sensitive paint(PSP) technique to obtain the unsteady pressure distribution on the whole blade surface and to capture the shock oscillation characteristics caused by SBLI.In addition,the Reynolds Averaged Navier Stokes simulations were used to compute the three-dimensional steady flow field in the transonic cascade.It was found that the shock wave patterns and behaviors are affected evidently with the increase in incoming Mach number at the design flow angle,especially with the presence of the separation bubble caused by SBLI.The time-averaged pressure distribution on the blade surface measured by PSP technique showed a symmetric pressure filed at Mach numbers of 0.85,while the pressure field on the blade surface was an asymmetric one at Mach numbers of 0.90 and 0.95.The oscillation of the shock wave was closely with the flow separation bubble on the blade surface and could transverse over nearly one interval of the pressure taps.The oscillation of the shock wave may smear the pressure jump phenomenon measured by the pressure taps.

Structural uncertainty quantification of Reynolds-Averaged Navier–Stokes closures for various shock-wave/boundary layer interaction flows

Accurate prediction of Shock-Wave/Boundary Layer Interaction(SWBLI)flows has been a persistent challenge for linear eddy viscosity models.A major limitation lies in the isotropic representation of the Reynolds stress,as assumed under the Boussinesq approximation.Recent studies have shown promise in improving the prediction capability for incompressible separation flows by perturbing the Reynolds-stress anisotropy tensor.However,it remains uncertain whether this approach is effective for SWBLI flows,which involve compressibility and discontinuity.To address this issue,this study systematically quantifies the structural uncertainty of the anisotropy for oblique SWBLI flows.The eigenspace perturbation method is applied to perturb the anisotropy tensor predicted by the Menter Shear–Stress Transport(SST)model and reveal the impacts of anisotropy on the prediction of quantities of interest,such as separation and reattachment positions,wall static pressure,skin friction,and heat flux.The results demonstrate the potential and reveal the challenges of eigenspace perturbation in improving the SST model.Furthermore,a detailed analysis of turbulent characteristics is performed to identify the source of uncertainty.The findings indicate that eigenspace perturbation primarily affects turbulent shear stress,while the prediction error of the SST model is more related to turbulent kinetic energy.

Nonlinear Violence in Nonlinear Oscillations at High Energy

This paper focuses on the characteristics of solutions of nonlinear oscillatory systems in the limit of very high oscillation energy, E;specifically, systems, in which the nonlinear driving force grows with energy much faster for x(t) close to the turning point, a(E), than at any position, x(t), that is not too close to a(E). This behavior dominates important aspects of the solutions. It will be called “nonlinear violence”. In the vicinity of a turning point, the solution of a nonlinear oscillatory systems that is affected by nonlinear violence exhibits the characteristics of boundary-layer behavior (independently of whether the equation of motion of the system can or cannot be cast in the traditional form of a boundary-layer problem.): close to a(E), x(t) varies very rapidly over a short time interval (which vanishes for E → ∞). In traditional boundary layer systems this would be called the “inner” solution. Outside this interval, x(t) soon evolves into a moderate profile (e.g. linear in time, or constant)—the “outer” solution. In (1 + 1)-dimensional nonlinear energy-conserving oscillators, if the solution is reflection-invariant, nonlinear violence determines the characteristics of the whole solution. For large families of nonlinear oscillatory systems, as E → ∞, the solutions for x(t) tend to common, indistinguishable profiles, such as periodic saw-tooth profiles or step-functions. If such profiles are observed experimentally in high-energy oscillations, it may be difficult to decipher the dynamical equations that govern the motion. The solution of motion in a central field with a non-zero angular momentum exhibits extremely fast rotation around a turning point that is affected by nonlinear violence. This provides an example for the possibility of interesting phenomena in (1 + 2)-dimensional oscillatory systems.

Extracorporeal shock wave lithotripsy for pancreatic and large common bile duct stones

Extraction of large pancreatic and common bile duct(CBD)calculi has always challenged the therapeutic endoscopist.Extracorporeal shockwave lithotripsy(ESWL)is an excellent tool for patients with large pancreatic and CBD calculi that are not amenable to routine endotherapy.Pancreatic calculi in the head and body are targeted by ESWL,with an aim to fragment them to<3 mm diameter so that they can be extracted by subsequent endoscopic retrograde cholangio-pancreatography(ERCP).In our experience,complete clearance of the pancreatic duct was achieved in 76% and partial clearance in 17%of 1006 patients.Short-term pain relief with reduction in the number of analgesics ingested was seen in 84%of these patients.For large CBD calculi,a nasobiliary tube is placed to help target the calculi,as well as bathe the calculi in salinea simple maneuver which helps to facilitate fragmenta-tion.The aim is to fragment calculi to<5 mm size and clear the same during ERCP.Complete clearance of the CBD was achieved in 84.4%of and partial clearance in 12.3%of 283 patients.More than 90%of the patients with pancreatic and biliary calculi needed three or fewer sessions of ESWL with 5000 shocks being de-livered at each session.The use of epidural anesthesia helped in reducing patient movement.This,together with the better focus achieved with newer third-gen-eration lithotripters,prevents collateral tissue damage and minimizes the complications.Complications in our experience with nearly 1300 patients were minimal,and no extension of hospital stay was required.Similar rates of clearance of pancreatic and biliary calculi with minimal adverse effects have been reported from the centers where ESWL is performed regularly.In view of its high efficiency,non-invasive nature and low complication rates,ESWL can be offered as the first-line therapy for selected patients with large pancreatic and CBD calculi.

Direct numerical simulation of compressible turbulent flows

This paper reviews the authors＇ recent studies on compressible turbulence by using direct numerical simulation （DNS）,including DNS of isotropic（decaying） turbulence, turbulent mixing-layer,turbulent boundary-layer and shock/boundary-layer interaction.Turbulence statistics, compressibility effects,turbulent kinetic energy budget and coherent structures are studied based on the DNS data.The mechanism of sound source in turbulent flows is also analyzed. It shows that DNS is a powerful tool for the mechanistic study of compressible turbulence.

Boundary-layer transition prediction using a simplified correlation-based model

This paper describes a simplified transition model based on the recently developed correlation-based γ - Reot transition model. The transport equation of transition momentum thick- ness Reynolds number is eliminated for simplicity, and new transition length function and critical Reynolds number correlation are proposed. The new model is implemented into an in-house com- putational fluid dynamics （CFD） code and validated for low and high-speed flow cases, including the zero pressure flat plate, airfoils, hypersonic flat plate and double wedge. Comparisons between the simulation results and experimental data show that the boundary-layer transition phenomena can be reasonably illustrated by the new model, which gives rise to significant improvements over the fully laminar and fully turbulent results. Moreover, the new model has comparable features of accuracy and applicability when compared with the original 3＇ - Reot model. In the meantime, the newly proposed model takes only one transport equation of intermittency factor and requires fewer correlations, which simplifies the original model greatly. Further studies, especially on separation- induced transition flows, are required for the improvement of the new model.

Combination of low-energy shock-wave therapy and bone marrow mesenchymal stem cell transplantation to improve the erectile function of diabetic rats

Stem cell transplantation and low-energy shock-wave therapy （LESWT） have emerged as potential and effective treatment protocols for diabetic erectile dysfunction. During the tracking of transplanted stem cells in diabetic erectile dysfunction models, the number of visible stem cells was rather low and decreased quickly. LESWT could recruit endogenous stem cells to the cavernous body and improve the microenvironment in diabetic cavernous tissue. Thus, we deduced that LESWT might benefit transplanted stem cell survival and improve the effects of stem cell transplantation. In this research, 42 streptozotocin-induced diabetic rats were randomized into four groups： the diabetic group （n = 6）, the LESWT group （n = 6）, the bone marrow-derived mesenchymal stem cell （BMSC） transplantation group （n = 15）, and the combination of LESWT and BMSC transplantation group （n = 15）. One and three days after BMSC transplantation, three rats were randomly chosen to observe the survival numbers of BMSCs in the cavernous body. Four weeks after BMSC transplantation, the following parameters were assessed： the surviving number of transplanted BMSCs in the cavernous tissue, erectile function, real-time polymerase chain reaction, and penile immunohistochemical assessment. Our research found that LESWT favored the survival of transplanted BMSCs in the cavernous body, which might be related to increased stromal cell-derived factor-1 expression and the enhancement of angiogenesis in the diabetic cavernous tissue. The combination of LESWT and BMSC transplantation could improve the erectile function of diabetic erectile function rats more effectively than LESWT or BMSC transplantation performed alone.

Treatment of urinary lithiasis following kidney transplantation with extracorporeal shock-wave lithotripsy

Background The incidence of urinary lithiasis following kidney transplantation is very low, and decision-supporting data are not available. The aim of this study was to review the diagnosis and treatment of urinary lithiasis following kidney transplantation, which is of realistic significance to reduce urinary lithiasis following kidney transplantation, prolong the survival of renal allografts.Methods The incidence, diagnosis and treatment of urinary lithiasis in ten patients following kidney transplantation were analyzed retrospectively. Seven out of these patients had stones sized approximately 0.4-1.1 cm, and they were treated with low-voltage, low-frequency extracorporeal shock-wave lithotripsy （ESWL）. Two patients had stones sized ＜0.3 cm and they underwent cystoscopy and ureteroscopy. The ureteral catheter endoscopes were inserted in a retrograde manner to mobilize stones repeatedly. After elimination of obstruction, a ureteral double J stent was indwelt.One patient had a pelvic stone （1.2 cm）, which was removed surgically.Results The major clinical manifestations were hematuria, oliguria or anuria. Some patients were asymptomatic and they were diagnosed through laboratory tests and imaging examinations, e.g., ultrasonography. After elimination of obstruction, subjective symptoms disappeared in all patients, and the function of renal allografts recovered. A six-month follow-up indicated no remnant stones or lithiasis relapse.Conclusions The diagnosis and treatment of renal allograft lithiasis are challenging. After prompt and appropriate treatment, the prognosis was satisfactory, and permanent renal functional impairment did not occur in most patients.

Large-eddy simulation of shock-wave/turbulent boundary layer interaction with and without Spark Jet control

The efficiency and mechanism of an active control device ＂＇Spark Jet＂ and its application in shock-induced separation control are studied using large-eddy simulation in this paper. The base flow is the interaction of an oblique shock-wave generated by 8° wedge and a spatially-developing Ma = 2.3 turbulent boundary layer. The Reynolds number based on the incoming flow property and the boundary layer displacement thickness at the impinging point without shock-wave is 20000. The detailed numerical approaches were presented. The inflow turbulence was generated using the digital filter method to avoid artificial temporal or streamwise periodicity. The , merical results including velocity profile, Reynolds stress profile, skin friction, and wall pressure were sys- tematically validated against the available wind tunnel particle image velocimetry （PIV） measure- ments of the same flow condition. Further study on the control of flow separation due to the strong shock-viscous interaction using an active control actuator ＂＇Spark Jet＇＂ was conducted. The single-pulsed characteristic of the device was obtained and compared with the experiment. Both instantaneous and time-averaged flow fields have shown that the jet flow issuing from the actuator cavity enhances the flow mixing inside the boundary layer, making the boundary layer more resis- tant to flow separation. Skin friction coefficient distribution shows that the separation bubble length is reduced by about 35% with control exerted.

Large Eddy Simulation of Turbulent Channel Flow with 3D Roughness Using a Roughness Element Model

Large eddy simulation of turbulent channel flow with dense and small 3D roughness elements is carried out using a roughness element model Profiles of mean Reynolds stress, mean velocity and rms velocity as well as turbulent structures near the wall are obtained. The shear stress in the rough wall is larger than that in the smooth wall side and the rough wall has a larger influence on the channel flow. Profiles of mean streamwise velocity near the wall have logarithmic velocity distributions for both smooth and roughness walls, while there is a velocity decrease for the rough wall due to larger fractional drag. All the three components of rms velocities in the rough wall region are larger than that in the smooth wall region, and the roughness elements on the wall increase turbulent intensity in all directions. The s^reak spacing and average diameter of near wall quasi-s^reamwise vortices increase with the presence of roughness elements on the wall and it is shown that the rough wall induces complex and strong streamwise vortices. Results of dense and small 3D roughness elements in both turbulent statistics and structure, obtained with a relatively simple method, are found to be comparable to related experiments.

A study on turbulence transportation and modification of Spalart–Allmaras model for shock-wave/turbulent boundary layer interaction flow

It is of great significance to improve the accuracy of turbulence models in shock-wave/ boundary layer interaction flow. The relationship between the pressure gradient, as well as the shear layer, and the development of turbulent kinetic energy in impinging shock-wave/turbulent bound- ary layer interaction flow at Mach 2.25 is analyzed based on the data of direct numerical simulation （DNS）. It is found that the turbulent kinetic energy is amplified by strong shear in the separation zone and the adverse pressure gradient near the separation point. The pressure gradient was non-dimensionalised with local density, velocity, and viscosity. Spalart Allmaras （S A） model is modified by introducing the non-dimensional pressure gradient into the production term of the eddy viscosity transportation equation. Simulation results show that the production and dissipation of eddy viscosity are strongly enhanced by the modification of S-A model. Compared with DNS and experimental data, the wall pressure and the wall skin friction coefficient as well as the velocity profile of the modified S-A model are obviously improved. Thus it can be concluded that the mod- ification of S-A model with the pressure gradient can improve the predictive accuracy for simulat- ing the shock-wave/turbulent boundary laver interaction.

Application of focused laser differential interferometer to hypersonic boundary-layer instability study

Accurate prediction of hypersonic boundary-layer transition plays an important role in thermal protection system design of hypersonic vehicles.Restricted by the capability of spatial diagnostics for hypersonic boundary-layer study,quite a lot of problems of hypersonic boundary-layer transition,such as nonlinearity and receptivity,remain outstanding.This work reports the application of focused laser differential interferometer to instability wave development across hypersonic boundary-layer on a flared cone model.To begin with,the focused laser differential interferometer is designed and set up in a Mach number 6 hypersonic quiet wind tunnel with the focal point in the laminar boundary-layer of a 5 degree half-angle flared cone model.Afterwards,instability experiments are carried out by traversing the focal point throughout the hypersonic boundary-layer and the density fluctuation along the boundary-layer profile is measured and analyzed.The results show that three types of instability waves ranging from 10 k Hz to over 1 MHz are co-existing in the hypersonic boundary-layer,indicating the powerful capability of focused laser differential interferometer in dynamic response resolution for instability wave study in hypersonic flow regime;furthermore,quantitative analyses including spectra and bicoherence analysis of instability waves throughout the hypersonic boundary-layer for both cold and heated cone models are performed.