目的介绍SF-36评分系统应用于人工关节置换术患者以评估其健康状况。方法入选2012年至2014年58例全髋关节置换患者(total hip replacement,THR),131例全膝关节置换患者(total knee replacement,TKR),分别于术前和术后6个月使用SF-36量表...目的介绍SF-36评分系统应用于人工关节置换术患者以评估其健康状况。方法入选2012年至2014年58例全髋关节置换患者(total hip replacement,THR),131例全膝关节置换患者(total knee replacement,TKR),分别于术前和术后6个月使用SF-36量表,Harris量表(THR患者),膝关节学会评分(Knee Society Score,KSS)量表(TKR患者)对患者进行评估;并对评分结果进行Pearson相关分析。结果最终获得THR完整随访53例,TKR完整随访124例,相关性检验显示36条目健康调查量表(36-Item Short-Form Health Survey,SF-36)与Harris量表及KSS量表均呈显著性正相关关系(双侧,P<0.01)。结论 SF-36量表能够较好的反映人工关节置换术后患者健康状况包括生理和心理两方面的变化,应用于此类患者具有相当的效度和信度。展开更多
Objectives: Osteoarthritis (OA) has a dramatic impact on patients’ health related quality of life (HRQoL). Chronic use of analgesics and anti-inflammatory medications for pain management may improve symptoms but on l...Objectives: Osteoarthritis (OA) has a dramatic impact on patients’ health related quality of life (HRQoL). Chronic use of analgesics and anti-inflammatory medications for pain management may improve symptoms but on long term may affect HRQoL negatively. The objective of the present study was to compare the impact of two different classes of analgesics, traditional non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclo-oxygenase-2 (COX-2) inhibitors on HRQoL among osteoarthritis patients using the SF-36 questionnaire. Methods: Clinic based cross-sectional study conducted at Al-Qassimi Hospital, Sharjah, United Arab Emirates (UAE), over a period of six months. Ethical Approval was obtained from the ethics committee at Al-Qassimi Clinical Research Center. Total of 200 osteoarthritis patients fulfilling the inclusion and exclusion criteria were involved in the study. Patients’ demographics were collected from their medical records. The Medical Outcome Study Short-Form 36 (SF-36) questionnaire was used to measure patients’ HRQoL. SF-36 data were scored using health outcomes scoring software 4.5. Results: Mean age of the subjects was 62.19 ± 9.81 years with females constituting 151 (75.5%) of the patients. In general, females scored lower in most of the HRQoL domains compared to males and there was significant difference between the two groups in the mental health (p = 0.005) & mental component (p = 0.042) domains. Compared to selective COX-2 inhibitors, patients on NSAIDs scored higher on all domains of SF-36 except physical functioning. There was significant difference in mental health domain for patients treated with NSAIDs (p = 0.02). Celecoxib was only better than NSAIDs in osteoarthritis patients with more than one musculoskeletal disorders in the domain of bodily pain (p = 0.009). Conclusion: NSAIDs-treated patients did not differ significantly from celecoxib-treated patients in all domains of the SF-36 except for the mental health domain.展开更多
目的观察5E康复模式对维持性血液透析(maintenance hemodialysis,MHD)患者微炎症状态及生活质量的影响。方法选择2020年1月~2021年12月在苏州大学附属无锡市第九人民医院血液净化中心MHD患者120例。按照随机数表法分为对照组及观察组,...目的观察5E康复模式对维持性血液透析(maintenance hemodialysis,MHD)患者微炎症状态及生活质量的影响。方法选择2020年1月~2021年12月在苏州大学附属无锡市第九人民医院血液净化中心MHD患者120例。按照随机数表法分为对照组及观察组,各60例。对照组采用常规护理干预,观察组在常规护理基础上联合5E康复模式干预。比较2组患者微炎症指标[血清超敏C反应蛋白(hs-CRP)、肿瘤坏死因子α(TNF-α)及白细胞介素-6(IL-6)]、营养不良-炎症评分(malnutrition inflammation score,MIS)及健康状况调查表(36-item short form health survey,SF-36)各维度项目的变化。结果干预6个月后,观察组hs-CRP、TNF-α、IL-6水平及MIS评分均低于对照组(t=2.300、4.959、2.649、2.298,P=0.023、<0.001、0.009、0.024)。干预后观察组患者SF-36量表生理机能、生理职能、一般健康状况、躯体疼痛、精力、情感职能、社会功能维度得分均高于对照组(t=-2.527、-3.220、-2.963、0.002、-5.963、4.959、-4.177,P=0.013、0.002、0.004、0.001、<0.001、<0.001、<0.001)。结论5E康复模式能够有效改善MHD患者的微炎症状态及营养状态,并提高患者的生活质量。展开更多
目的:探讨甲状旁腺全切术(total parathyroidectomy,TPTX)对维持性血液透析(maintenance hemodialysis,MHD)患者临床指标及生活质量的影响。方法:回顾性分析89例继发性甲状旁腺功能亢进症(secondary hyperparathyroidism,SHPT)患者手术...目的:探讨甲状旁腺全切术(total parathyroidectomy,TPTX)对维持性血液透析(maintenance hemodialysis,MHD)患者临床指标及生活质量的影响。方法:回顾性分析89例继发性甲状旁腺功能亢进症(secondary hyperparathyroidism,SHPT)患者手术前后血清钙、磷、全段甲状旁腺激素(intact parathyroid hormone,IPTH)、碱性磷酸酶、血红蛋白、白蛋白等生化指标变化,应用肾脏病与生活质量问卷36(kidney disease quality of life 36,KDQOL-36)量表和36项简明健康调查问卷(the medical outcome 36-item short form health survey,SF-36)量表对患者进行手术前、后生活质量评估,比较手术前、后生活质量评分变化。结果:术后患者乏力、骨痛、皮肤瘙痒等症状明显改善。术后血清钙、磷、碱性磷酸酶、IPTH较术前明显下降(均P<0.01),血红蛋白、白蛋白较术前明显增加(P<0.01)。术前生活质量评分均较低,TPTX后生活质量评分均显著增加(P<0.01)。术前肾病相关生活质量、一般健康相关生活质量、综合生活质量与血红蛋白、白蛋白呈正相关,与年龄呈负相关(均P<0.05);肾病相关生活质量、综合生活质量与文化程度呈正相关(均P<0.05);一般健康相关生活质量与血清尿素氮、磷呈负相关(均P<0.05)。结论:TPTX可以显著改善难治性SHPT患者的临床指标,提高生活质量。展开更多
文摘目的介绍SF-36评分系统应用于人工关节置换术患者以评估其健康状况。方法入选2012年至2014年58例全髋关节置换患者(total hip replacement,THR),131例全膝关节置换患者(total knee replacement,TKR),分别于术前和术后6个月使用SF-36量表,Harris量表(THR患者),膝关节学会评分(Knee Society Score,KSS)量表(TKR患者)对患者进行评估;并对评分结果进行Pearson相关分析。结果最终获得THR完整随访53例,TKR完整随访124例,相关性检验显示36条目健康调查量表(36-Item Short-Form Health Survey,SF-36)与Harris量表及KSS量表均呈显著性正相关关系(双侧,P<0.01)。结论 SF-36量表能够较好的反映人工关节置换术后患者健康状况包括生理和心理两方面的变化,应用于此类患者具有相当的效度和信度。
文摘Objectives: Osteoarthritis (OA) has a dramatic impact on patients’ health related quality of life (HRQoL). Chronic use of analgesics and anti-inflammatory medications for pain management may improve symptoms but on long term may affect HRQoL negatively. The objective of the present study was to compare the impact of two different classes of analgesics, traditional non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclo-oxygenase-2 (COX-2) inhibitors on HRQoL among osteoarthritis patients using the SF-36 questionnaire. Methods: Clinic based cross-sectional study conducted at Al-Qassimi Hospital, Sharjah, United Arab Emirates (UAE), over a period of six months. Ethical Approval was obtained from the ethics committee at Al-Qassimi Clinical Research Center. Total of 200 osteoarthritis patients fulfilling the inclusion and exclusion criteria were involved in the study. Patients’ demographics were collected from their medical records. The Medical Outcome Study Short-Form 36 (SF-36) questionnaire was used to measure patients’ HRQoL. SF-36 data were scored using health outcomes scoring software 4.5. Results: Mean age of the subjects was 62.19 ± 9.81 years with females constituting 151 (75.5%) of the patients. In general, females scored lower in most of the HRQoL domains compared to males and there was significant difference between the two groups in the mental health (p = 0.005) & mental component (p = 0.042) domains. Compared to selective COX-2 inhibitors, patients on NSAIDs scored higher on all domains of SF-36 except physical functioning. There was significant difference in mental health domain for patients treated with NSAIDs (p = 0.02). Celecoxib was only better than NSAIDs in osteoarthritis patients with more than one musculoskeletal disorders in the domain of bodily pain (p = 0.009). Conclusion: NSAIDs-treated patients did not differ significantly from celecoxib-treated patients in all domains of the SF-36 except for the mental health domain.
文摘目的观察5E康复模式对维持性血液透析(maintenance hemodialysis,MHD)患者微炎症状态及生活质量的影响。方法选择2020年1月~2021年12月在苏州大学附属无锡市第九人民医院血液净化中心MHD患者120例。按照随机数表法分为对照组及观察组,各60例。对照组采用常规护理干预,观察组在常规护理基础上联合5E康复模式干预。比较2组患者微炎症指标[血清超敏C反应蛋白(hs-CRP)、肿瘤坏死因子α(TNF-α)及白细胞介素-6(IL-6)]、营养不良-炎症评分(malnutrition inflammation score,MIS)及健康状况调查表(36-item short form health survey,SF-36)各维度项目的变化。结果干预6个月后,观察组hs-CRP、TNF-α、IL-6水平及MIS评分均低于对照组(t=2.300、4.959、2.649、2.298,P=0.023、<0.001、0.009、0.024)。干预后观察组患者SF-36量表生理机能、生理职能、一般健康状况、躯体疼痛、精力、情感职能、社会功能维度得分均高于对照组(t=-2.527、-3.220、-2.963、0.002、-5.963、4.959、-4.177,P=0.013、0.002、0.004、0.001、<0.001、<0.001、<0.001)。结论5E康复模式能够有效改善MHD患者的微炎症状态及营养状态,并提高患者的生活质量。
文摘目的:探讨甲状旁腺全切术(total parathyroidectomy,TPTX)对维持性血液透析(maintenance hemodialysis,MHD)患者临床指标及生活质量的影响。方法:回顾性分析89例继发性甲状旁腺功能亢进症(secondary hyperparathyroidism,SHPT)患者手术前后血清钙、磷、全段甲状旁腺激素(intact parathyroid hormone,IPTH)、碱性磷酸酶、血红蛋白、白蛋白等生化指标变化,应用肾脏病与生活质量问卷36(kidney disease quality of life 36,KDQOL-36)量表和36项简明健康调查问卷(the medical outcome 36-item short form health survey,SF-36)量表对患者进行手术前、后生活质量评估,比较手术前、后生活质量评分变化。结果:术后患者乏力、骨痛、皮肤瘙痒等症状明显改善。术后血清钙、磷、碱性磷酸酶、IPTH较术前明显下降(均P<0.01),血红蛋白、白蛋白较术前明显增加(P<0.01)。术前生活质量评分均较低,TPTX后生活质量评分均显著增加(P<0.01)。术前肾病相关生活质量、一般健康相关生活质量、综合生活质量与血红蛋白、白蛋白呈正相关,与年龄呈负相关(均P<0.05);肾病相关生活质量、综合生活质量与文化程度呈正相关(均P<0.05);一般健康相关生活质量与血清尿素氮、磷呈负相关(均P<0.05)。结论:TPTX可以显著改善难治性SHPT患者的临床指标,提高生活质量。
