Accurate origin–destination(OD)demand prediction is crucial for the efficient operation and management of urban rail transit(URT)systems,particularly during a pandemic.However,this task faces several limitations,incl...Accurate origin–destination(OD)demand prediction is crucial for the efficient operation and management of urban rail transit(URT)systems,particularly during a pandemic.However,this task faces several limitations,including real-time availability,sparsity,and high-dimensionality issues,and the impact of the pandemic.Consequently,this study proposes a unified framework called the physics-guided adaptive graph spatial–temporal attention network(PAG-STAN)for metro OD demand prediction under pandemic conditions.Specifically,PAG-STAN introduces a real-time OD estimation module to estimate real-time complete OD demand matrices.Subsequently,a novel dynamic OD demand matrix compression module is proposed to generate dense real-time OD demand matrices.Thereafter,PAG-STAN leverages various heterogeneous data to learn the evolutionary trend of future OD ridership during the pandemic.Finally,a masked physics-guided loss function(MPG-loss function)incorporates the physical quantity information between the OD demand and inbound flow into the loss function to enhance model interpretability.PAG-STAN demonstrated favorable performance on two real-world metro OD demand datasets under the pandemic and conventional scenarios,highlighting its robustness and sensitivity for metro OD demand prediction.A series of ablation studies were conducted to verify the indispensability of each module in PAG-STAN.展开更多
Based on the changing law of municipal water demand,a trigonometric function model for short-term water demand forecast is established using the time-series analysis approach.The method for forecasting water demand du...Based on the changing law of municipal water demand,a trigonometric function model for short-term water demand forecast is established using the time-series analysis approach.The method for forecasting water demand during holidays and under unexpected events is also presented.Meanwhile,a computer software is developed.Through actual application,this method performs well and has high accuracy,so it can be applied to the daily operation of a water distribution system and lay a foundation for on-line optimal operation.展开更多
Based on the connotation of urban resilience and the main contradictions of China's urbanization,urban resilience is placed within the main daily activities contradictory scene of the urban man-land system to buil...Based on the connotation of urban resilience and the main contradictions of China's urbanization,urban resilience is placed within the main daily activities contradictory scene of the urban man-land system to build a theoretical framework of urban activity resilience.Relying on geographic big data,this study identifies the spatial characteristics of activity resilience,reveals the impact of activity environment on activity resilience in Nanjing,and proposes countermeasures.The main conclusions are as follows.1)Activity resilience presents a composite spatial structure of circles and clusters,and most areas are resilient but at a low level.2)There are significantly positive and negative global autocorrelation between activity resilience and activity scale,and activity stability.Simultaneously,there also exists a local spatial autocorrelation with the opposite positive and negative trends.3)Activity environment has a significant effect on activity resilience,and the degree and direction of influence among different dimensions and regions are heterogeneous.4)For activity resilience,it is necessary to increase the matching degree between the scale and stability of activities,and reduce the excessive concentration and flow of activities.For the activity environment,it is necessary to improve the accessibility of the ecological environment,strengthen the high-quality supply of the infrastructure environment,optimize the balance of the location environment,and promote the inclusiveness of the social environment.展开更多
AIM:To investigate the therapeutic efficacy of short- term, multiple daily dosing of intravenous interferon (IFN) in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B. METHODS:IFN-β was intrave...AIM:To investigate the therapeutic efficacy of short- term, multiple daily dosing of intravenous interferon (IFN) in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B. METHODS:IFN-β was intravenously administered at a total dose of 102 million international units (MIU) over a period of 28 d in 26 patients positive for HBeAg and HBV-DNA. IFN-beta was administered at doses of 2 MIU and 1 MIU on d 1, 3 MIU twice daily from d 2 to d 7, and 1 MIU thrice daily from d 8 to d 28. Patients were followed up for 24 wk after the end of treatment. RESULTS:Six months after the end of the treatment, loss of HBV-DNA occurred in 13 (50.0%) of the 26 patients, loss of HBeAg in 9 (34.6%), development of anti-HBe in 10 (38.5%), HBeAg seroconversion in 8 (30.8%), and normalization of alanine aminotransferase (ALT) levels in 11 (42.0%). CONCLUSION:This 4-wk long IFN-β therapy, which was much shorter than conventional therapy lasting 12 wk or even more than 1 year, produced therapeutic effects similar to those achieved by IFN-α or pegylated- IFN-α (peg-IFN). Fewer adverse effects, greater efficacy, and a shorter treatment period led to an improvement in patients’ quality of life. IFN-β is administered intravenously, whereas IFN-α is administered intramuscularly or subcutaneously. Because both interferons are known to bind to an identical receptor and exert antiviral effects through intracellular signal transduction, the excellent results of IFN-β found in this study may be attributed to the multiple doses allowed by the intravenous route.展开更多
The objective of this study is to evaluate the performance of three models for estimating daily evapotranspiration(ET) by employing flux observation data from three years(2007, 2008 and 2009) during the growing season...The objective of this study is to evaluate the performance of three models for estimating daily evapotranspiration(ET) by employing flux observation data from three years(2007, 2008 and 2009) during the growing seasons of winter wheat and rice crops cultivated in a farmland ecosystem(Shouxian County) located in the Huai River Basin(HRB), China. The first model is a two-step model(PM-Kc);the other two are one-step models(e.g., Rana-Katerji(R-K) and advection-aridity(AA)). The results showed that the energy closure degrees of eddy covariance(EC) data during winter wheat and rice-growing seasons were reasonable in the HRB, with values ranging from 0.84 to 0.91 and R2 of approximately 0.80. Daily ET of winter wheat showed a slow decreasing trend followed by a rapid increase, while that of rice presented a decreasing trend after an increase. After calibrating the crop coefficient(Kc), the PM–Kc model performed better than the model using the Kc recommended by the Food and Agricultural Organization(FAO). The calibrated key parameters of the R-K model and AA model showed better universality. After calibration, the simulation performance of the PM-Kc model was satisfactory. Both the R-K model and AA model underestimated the daily ET of winter wheat and rice. Compared with that of the R-K model, the simulation result of the AA model was better, especially in the simulation of daily ET of rice. Overall, this research highlighted the consistency of the PM-Kc model to estimate the water demand for rice and wheat crops in the HRB and in similar climatic regions in the world.展开更多
Modelling of intraday increases in peak electricity demand using an autoregressive moving average-exponential generalized autoregressive conditional heteroskedastic-generalized single Pareto (ARMA-EGARCH-GSP) approach...Modelling of intraday increases in peak electricity demand using an autoregressive moving average-exponential generalized autoregressive conditional heteroskedastic-generalized single Pareto (ARMA-EGARCH-GSP) approach is discussed in this paper. The developed model is then used for extreme tail quantile estimation using daily peak electricity demand data from South Africa for the period, years 2000 to 2011. The advantage of this modelling approach lies in its ability to capture conditional heteroskedasticity in the data through the EGARCH framework, while at the same time estimating the extreme tail quantiles through the GSP modelling framework. Empirical results show that the ARMA-EGARCH-GSP model produces more accurate estimates of extreme tails than a pure ARMA-EGARCH model.展开更多
Accurate short-term forecasting of heating energy demand is needed for achieving optimal building energy management,cost savings,environmental sustainability,and responsible energy consumption.Furthermore,short-term h...Accurate short-term forecasting of heating energy demand is needed for achieving optimal building energy management,cost savings,environmental sustainability,and responsible energy consumption.Furthermore,short-term heating energy prediction contributes to zero-energy building performance in cold climates.Given the critical importance of short-term forecasting in heating energy management,this study evaluated six prevalent deep-learning algorithms to predict energy load,including single and hybrid models.The overall best-performing predictors were hybrid models using Convolutional Neural Networks,regardless of whether they were multivariate or univariate.Nevertheless,while the multivariate models performed better in the first hour,the univariate models often were more accurate in the final 24 h.Thus,the best-performing predictor of the first timestep was a multivariate hybrid Convolutional Neural Network–Recurrent Neural Network model with a coefficient of determination(R^(2))of 0.98 and the lowest mean absolute error.Yet,the best-performing predictor of the final timestep was the univariate hybrid model Convolutional Neural Network–Long Short-Term Memory with an R^(2)of 0.80.Also,the prediction accuracy of the best-performing multivariate hybrid models reduced faster per hour compared to the univariate models.These findings suggest that multivariate models may be better suited for early timestep predictions,while univariate models may be better suited for later time steps.Hence,combining the models can enhance accuracy at various timesteps for achieving high fidelity in forecasting and offering a comprehensive tool for energy management.展开更多
基金supported by the National Natural Science Foundation of China(72288101,72201029,and 72322022).
文摘Accurate origin–destination(OD)demand prediction is crucial for the efficient operation and management of urban rail transit(URT)systems,particularly during a pandemic.However,this task faces several limitations,including real-time availability,sparsity,and high-dimensionality issues,and the impact of the pandemic.Consequently,this study proposes a unified framework called the physics-guided adaptive graph spatial–temporal attention network(PAG-STAN)for metro OD demand prediction under pandemic conditions.Specifically,PAG-STAN introduces a real-time OD estimation module to estimate real-time complete OD demand matrices.Subsequently,a novel dynamic OD demand matrix compression module is proposed to generate dense real-time OD demand matrices.Thereafter,PAG-STAN leverages various heterogeneous data to learn the evolutionary trend of future OD ridership during the pandemic.Finally,a masked physics-guided loss function(MPG-loss function)incorporates the physical quantity information between the OD demand and inbound flow into the loss function to enhance model interpretability.PAG-STAN demonstrated favorable performance on two real-world metro OD demand datasets under the pandemic and conventional scenarios,highlighting its robustness and sensitivity for metro OD demand prediction.A series of ablation studies were conducted to verify the indispensability of each module in PAG-STAN.
基金Natural Science Foundation of China!(No.598780 30 )
文摘Based on the changing law of municipal water demand,a trigonometric function model for short-term water demand forecast is established using the time-series analysis approach.The method for forecasting water demand during holidays and under unexpected events is also presented.Meanwhile,a computer software is developed.Through actual application,this method performs well and has high accuracy,so it can be applied to the daily operation of a water distribution system and lay a foundation for on-line optimal operation.
基金Under the auspices of National Social Science Fund of China(No.20AZD040)the Program B for Outstanding PhD Candidate of Nanjing University(No.202002B103)。
文摘Based on the connotation of urban resilience and the main contradictions of China's urbanization,urban resilience is placed within the main daily activities contradictory scene of the urban man-land system to build a theoretical framework of urban activity resilience.Relying on geographic big data,this study identifies the spatial characteristics of activity resilience,reveals the impact of activity environment on activity resilience in Nanjing,and proposes countermeasures.The main conclusions are as follows.1)Activity resilience presents a composite spatial structure of circles and clusters,and most areas are resilient but at a low level.2)There are significantly positive and negative global autocorrelation between activity resilience and activity scale,and activity stability.Simultaneously,there also exists a local spatial autocorrelation with the opposite positive and negative trends.3)Activity environment has a significant effect on activity resilience,and the degree and direction of influence among different dimensions and regions are heterogeneous.4)For activity resilience,it is necessary to increase the matching degree between the scale and stability of activities,and reduce the excessive concentration and flow of activities.For the activity environment,it is necessary to improve the accessibility of the ecological environment,strengthen the high-quality supply of the infrastructure environment,optimize the balance of the location environment,and promote the inclusiveness of the social environment.
文摘AIM:To investigate the therapeutic efficacy of short- term, multiple daily dosing of intravenous interferon (IFN) in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B. METHODS:IFN-β was intravenously administered at a total dose of 102 million international units (MIU) over a period of 28 d in 26 patients positive for HBeAg and HBV-DNA. IFN-beta was administered at doses of 2 MIU and 1 MIU on d 1, 3 MIU twice daily from d 2 to d 7, and 1 MIU thrice daily from d 8 to d 28. Patients were followed up for 24 wk after the end of treatment. RESULTS:Six months after the end of the treatment, loss of HBV-DNA occurred in 13 (50.0%) of the 26 patients, loss of HBeAg in 9 (34.6%), development of anti-HBe in 10 (38.5%), HBeAg seroconversion in 8 (30.8%), and normalization of alanine aminotransferase (ALT) levels in 11 (42.0%). CONCLUSION:This 4-wk long IFN-β therapy, which was much shorter than conventional therapy lasting 12 wk or even more than 1 year, produced therapeutic effects similar to those achieved by IFN-α or pegylated- IFN-α (peg-IFN). Fewer adverse effects, greater efficacy, and a shorter treatment period led to an improvement in patients’ quality of life. IFN-β is administered intravenously, whereas IFN-α is administered intramuscularly or subcutaneously. Because both interferons are known to bind to an identical receptor and exert antiviral effects through intracellular signal transduction, the excellent results of IFN-β found in this study may be attributed to the multiple doses allowed by the intravenous route.
基金supported by the National Natural Science Foundation of China (41905100)the Anhui Provincial Natural Science Foundation, China (1908085QD171)+3 种基金the Anhui Agricultural University Science Foundation for Young Scholars, China (2018zd07)the Anhui Agricultural University Introduction and Stabilization of Talent Fund, China (yj2018-57)the National Key Research and Development Program of China (2018YFD0300905)the Postgraduate Research and Practice Innovation Program of Jiangsu Province, China (KYCX17_0885)。
文摘The objective of this study is to evaluate the performance of three models for estimating daily evapotranspiration(ET) by employing flux observation data from three years(2007, 2008 and 2009) during the growing seasons of winter wheat and rice crops cultivated in a farmland ecosystem(Shouxian County) located in the Huai River Basin(HRB), China. The first model is a two-step model(PM-Kc);the other two are one-step models(e.g., Rana-Katerji(R-K) and advection-aridity(AA)). The results showed that the energy closure degrees of eddy covariance(EC) data during winter wheat and rice-growing seasons were reasonable in the HRB, with values ranging from 0.84 to 0.91 and R2 of approximately 0.80. Daily ET of winter wheat showed a slow decreasing trend followed by a rapid increase, while that of rice presented a decreasing trend after an increase. After calibrating the crop coefficient(Kc), the PM–Kc model performed better than the model using the Kc recommended by the Food and Agricultural Organization(FAO). The calibrated key parameters of the R-K model and AA model showed better universality. After calibration, the simulation performance of the PM-Kc model was satisfactory. Both the R-K model and AA model underestimated the daily ET of winter wheat and rice. Compared with that of the R-K model, the simulation result of the AA model was better, especially in the simulation of daily ET of rice. Overall, this research highlighted the consistency of the PM-Kc model to estimate the water demand for rice and wheat crops in the HRB and in similar climatic regions in the world.
文摘Modelling of intraday increases in peak electricity demand using an autoregressive moving average-exponential generalized autoregressive conditional heteroskedastic-generalized single Pareto (ARMA-EGARCH-GSP) approach is discussed in this paper. The developed model is then used for extreme tail quantile estimation using daily peak electricity demand data from South Africa for the period, years 2000 to 2011. The advantage of this modelling approach lies in its ability to capture conditional heteroskedasticity in the data through the EGARCH framework, while at the same time estimating the extreme tail quantiles through the GSP modelling framework. Empirical results show that the ARMA-EGARCH-GSP model produces more accurate estimates of extreme tails than a pure ARMA-EGARCH model.
基金funded by the Natural Sciences and Engineering Research Council(NSERC)Discovery Grant,grant number RGPIN-05481.
文摘Accurate short-term forecasting of heating energy demand is needed for achieving optimal building energy management,cost savings,environmental sustainability,and responsible energy consumption.Furthermore,short-term heating energy prediction contributes to zero-energy building performance in cold climates.Given the critical importance of short-term forecasting in heating energy management,this study evaluated six prevalent deep-learning algorithms to predict energy load,including single and hybrid models.The overall best-performing predictors were hybrid models using Convolutional Neural Networks,regardless of whether they were multivariate or univariate.Nevertheless,while the multivariate models performed better in the first hour,the univariate models often were more accurate in the final 24 h.Thus,the best-performing predictor of the first timestep was a multivariate hybrid Convolutional Neural Network–Recurrent Neural Network model with a coefficient of determination(R^(2))of 0.98 and the lowest mean absolute error.Yet,the best-performing predictor of the final timestep was the univariate hybrid model Convolutional Neural Network–Long Short-Term Memory with an R^(2)of 0.80.Also,the prediction accuracy of the best-performing multivariate hybrid models reduced faster per hour compared to the univariate models.These findings suggest that multivariate models may be better suited for early timestep predictions,while univariate models may be better suited for later time steps.Hence,combining the models can enhance accuracy at various timesteps for achieving high fidelity in forecasting and offering a comprehensive tool for energy management.