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The Influence of RNA Secondary Structure on the Efficiency of si RNA Silencing
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作者 SUN Ying GUI Jian-bin CHEN Zhao-xue 《Chinese Journal of Biomedical Engineering(English Edition)》 CSCD 2015年第4期179-184,共6页
In the application of RNAi technology,it is an essential step to design siR NA applicable to target gene.At present,there are many researches and conclusions on siR NA design.This paper aims to the influences of mR NA... In the application of RNAi technology,it is an essential step to design siR NA applicable to target gene.At present,there are many researches and conclusions on siR NA design.This paper aims to the influences of mR NA secondary structure or siR NA antisense-strand secondary structure on siR NA silence efficiency.The paper also discusses the problems and sets out further insights in the research. 展开更多
关键词 RNA interference RNA secondary structure sirna silence efficiency
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