Flower morphology of Allium(Amaryllidaceae)and its systematic significance

Allium is a complicated genus that includes approximately 1000 species.Although its morphology is well studied,the taxonomic importance of many morphological traits,including floral traits,are poorly understood.Here,we examined and measured the floral characteristics of 87 accessions of 74 Allium taxa(belonging to 30 sections and nine subgenera)from Central to Eastern Asian countries.We then examined the taxonomic relationships between select flower characteristics and a phylogenetic tree based on ITS sequences.Our results confirm that floral morphology provides key taxonomic information to assess species delimitation in Allium.We found that perianth color is an important characteristic within the subg.Melanocrommyum,Polyprason,and Reticulatobulbosa.In subg.Allium,Cepa,and Rhizirideum,significant characteristics include ovary shape,perianth shape,and inner tepal apex.For species in subg.Angunium,the key taxonomic character is ovule number(only one ovule in per locule).In the subg.Allium,Cepa,Polyprason,and Reticulatobulbosa,which belong to the third evolutionary line of Allium,hood-like appendages occur in the ovary,although these do not occur in subg.Rhizirideum.Our results also indicated that the flower morphology of several species in some sections are not clearly distinguished,e.g.,sect.Sacculiferum(subg.Cepa)and sect.Tenuissima(subg.Rhizirideum).This study provides detailed photographs and descriptions of floral characteristics and information on general distributions,habitats,and phenology of the studied taxa.

A Meta-Analysis of the Prognostic and Clinicopathological Significance of circZFR in Human Gastrointestinal Cancers

Background: Studies of gastrointestinal (GIT) cancers have shown that circZFR could be involved in the development and progression of various GIT cancers. However, small sample sizes limit the clinical significance of these studies. Here, a meta-analysis was conducted to ascertain the actual involvement of circZFR in the development and prognosis of GIT cancers. Methods: PubMed, Embase, Web of Science, and the Cochrane Library were searched up to December 31, 2023. Hazard ratios (HRs) or odds ratios (ORs) with 95% confidence intervals (CIs) were pooled to evaluate the association between circZFR expression and overall survival (OS). Publication bias was measured using the funnel plot and Egger’s test. Results: 10 studies having 659 participants were enrolled for meta-analysis. High circZFR expression was associated with poor OS (HR = 1.4, 95% CI: 1.20, 1.70). High circZFR expression also predicted larger tumor size (OR = 4.38, 95% CI 2.65, 7.25), advanced clinical stage (OR = 5.33, 95% CI 3.10, 9.16), and tendency for distant metastasis (OR = 2.89, 95% CI: 1.62, 5.11), but was not related to age, gender, and histological grade. Conclusions: In summary, high circZFR expression was associated with poor OS, larger tumor size, advanced stage cancer and tendency for distant metastasis. These findings suggested that circZFR could be a prognostic marker for GIT cancers.

Nomogram to predict gas-related complications during transoral endoscopic resection of upper gastrointestinal submucosal lesions:Clinical significance

Transoral endoscopic resections in treating upper gastrointestinal submucosal lesions have the advantages of maintaining the integrity of the gastrointestinal lumen,avoiding perforation and reducing gastrointestinal fistulae.They are becoming more widely used in clinical practice,but,they may also present a variety of complications.Gas-related complications are one of the most common,which can be left untreated if the symptoms are mild,but in severe cases,they can lead to rapid changes in the respiratory and circulatory systems in a short period,which can be life-threatening.Therefore,it is important to predict the occurrence of gas-related complications early and take preventive measures actively.Based on the authors'results in the prepublication of the article“Nomogram to predict gas-related complications during transoral endoscopic resection of upper gastrointestinal submucosal lesions,”and in conjunction with our evaluation and additions to the relevant content,radiographs may help screen patients at high risk for gas-related complications.Controlling blood glucose levels,shortening the duration of surgery,and choosing the most appropriate surgical resection may positively impact the prognosis of patients at high risk for gas-related complications during transoral endoscopic resection of upper gastrointestinal submucosal lesions.

A Study on the Educational Significance Guidance Plan Value of the Jumong Myth Using STEAM

Jumong is a legendary figure in Korean mythology.He is depicted as a genius archer,a brilliant mind with horses,a god who rules the rivers and the sky.Jumong is a mythical character who is believed to be of divine descent and to possess superhuman abilities that humans cannot match.The myth of Jumong is a very competitive content that can compete on a global scale.However,in order for it to be successful,it is necessary to be able to reinterpret our mythology to suit the times and reproduce it culturally.To this end,the realistic globalization of Korean classical literature should commence with the genre of Korean mythology.This paper presents the educational significance of the Jumong myth as a teaching-learning model,via STEAM(science,technology,engineering,arts,and mathematics),on the theme of Korean mythology.As we enter the era of artificial intelligence(AI)through the 4th Industrial Revolution,the most appropriate teaching and learning method,the convergence class,will provide an opportunity for students living in modern times to discover the cultural archetypes that allow them to recognise themselves as individuals and us as a collective,and to find the roots of the myth to positively renew their identity.Furthermore,it is my hope that they will rediscover and appreciate the representative work of Korean mythology,Gojomong,the eponymous story of Goguryeo.

Exploring the Significance and Implementation Strategies of Mental Health Education for College Students

College students are influenced by diverse cultures in the new era,thus their inner world is rich and changing rapidly.The acceleration of social rhythm can easily lead to different kinds of psychological problems.Mental health education is people-oriented,using scientific methods and means to train high-quality talents with all-round development across the world.A healthy psychological state can promote the sound development of students,make them establish correct core social values,and realize self-value.At present,there are some problems in university mental health education,such as single form and imperfect system.At the same time,college education plays an important role in the formation of ideas for college students’ideological values.As a front-line student worker,college counselors should cooperate with the school’s psychological departments to improve the college psychological education system,rationally plan the psychological teaching program,and pay attention to the college students’mental health education.The government should also take into account the need to ensure that the education system is not undermined by the lack of a comprehensive and effective education system.

Analysis of the Significance of Key Points of Patient Interventional Psychological Care and Pain Care

Interventional therapy has become increasingly popular in clinical practice due to advancements in medical technology.However,patients often experience psychological and physiological pressure due to its invasive nature.The management of patient discomfort and tension is crucial to ensure effective treatment.Psychological and pain management are essential components of interventional therapy,as they significantly impact patient recovery and prognosis.This article discussed the importance of interventional psychological and pain care for patients,starting with the development and spread of interventional therapy.The significance of providing high-quality nursing services to patients and improving their quality of life was also discussed.

Expression of CD151 in Gastric Cancer Tissues and Its Clinical Significance

Objective:To explore the expression of CD151 in gastric cancer tissues and its clinical significance.Methods:Immunohistochemistry was employed to detect the expression of CD151 in gastric cancer tissues and adjacent normal tissues.The relationship between CD151 expression and the clinicopathological characteristics of gastric cancer was analyzed.Results:The expression of CD151 in gastric cancer tissues was significantly higher than in adjacent normal tissues(P<0.05).It was associated with the degree of differentiation,depth of invasion,lymph node metastasis,and TNM staging of gastric cancer.The survival time of patients with high CD151 expression was significantly shorter than that of those with low expression(P<0.05).Conclusion:High expression of CD151 in gastric cancer tissues is correlated with the malignant biological behavior of gastric cancer and can serve as an indicator for evaluating the prognosis of gastric cancer.

Distribution and geochemical significance of trace elements in kerogens from Ediacaran–Lower Cambrian strata in South China

Some trace elements(TEs),both bio-essential and redox-sensitive,are promising tracers of Earth’s surface processes.As an essential sedimentary organic matter,kerogen may have inherited and retained the key TEs from organisms.In this study,the distribution of TEs in kerogens from two sections(Dongkanshang and Fengtan) in South China was analyzed to explore its biogeochemical significance during Ediacaran-Lower Cambrian.Compared with V and Zn,the relative concentrations of Co,Ni,Cu,and Mo were generally higher in kerogens than in the whole rocks.Enrichment of TEs in the kerogen was involved in the selective utilization of TEs by different organic precursors and the competition of sulfide in the depositional environment.The significant content of TEs in the kerogens from deep-water facies corresponded to a more negative δ^(13) Ckeras a result of the dominant taxa of chemo autotrophs with tremendous bioaccumulation potential for trace metals and the reduction conditions favorable for organic matter preservation.Furthermore,the content variations of trace elements in the kerogens coincided with the rise and fall of the Ediacaran biota,implying that the trace elements might have played an important role in early life evolution.

Environmental significance and hydrochemical characteristics of rivers in the western region of the Altay Mountains,China

Analysis of environmental significance and hydrochemical characteristics of river water in mountainous regions is vital for ensuring water security.In this study,we collected a total of 164 water samples in the western region of the Altay Mountains,China,in 2021.We used principal component analysis and enrichment factor analysis to examine the chemical properties and spatiotemporal variations of major ions(including F-,Cl-,NO_(3)-,SO_(4)^(2-),Li+,Na+,NH4+,K+,Mg^(2+),and Ca^(2+))present in river water,as well as to identify the factors influencing these variations.Additionally,we assessed the suitability of river water for drinking and irrigation purposes based on the total dissolved solids,soluble sodium percentage,sodium adsorption ratio,and total hardness.Results revealed that river water had an alkaline aquatic environment with a mean pH value of 8.00.The mean ion concentration was ranked as follows:Ca^(2+)>SO_(4)^(2-)>Na+>NO_(3)->Mg^(2+)>K+>Cl->F->NH_(4)+>Li+.Ca^(2+),SO_(4)^(2-),Na+,and NO_(3)-occupied 83%of the total ion concentration.In addition,compared with other seasons,the spatial variation of the ion concentration in spring was obvious.An analysis of the sources of major ions revealed that these ions originated mainly from carbonate dissolution and silicate weathering.The recharge impact of precipitation and snowmelt merely influenced the concentration of Cl-,NO_(3)-,SO_(4)^(2-),Ca^(2+),and Na+.Overall,river water was in pristine condition in terms of quality and was suitable for both irrigation and drinking.This study provides a scientific basis for sustainable management of water quality in rivers of the Altay Mountains.

Unveiling clinical significance and tumor immune landscape of CXCL12 in bladder cancer: Insights from multiple omics analysis

Objective: The interplay between chemokine C-X-C motif ligand 12(CXCL12) and its specific receptors is known to trigger various signaling pathways, contributing to tumor proliferation and metastasis. Consequently,targeting this signaling axis has emerged as a potential strategy in cancer therapy. However, the precise role of CXCL12 in clinical therapy, especially in immunotherapy for bladder cancer(BCa), remains poorly elucidated.Methods: We gathered multiple omics data from public databases to unveil the clinical relevance and tumor immune landscape associated with CXCL12 in BCa patients. Univariate and multivariate Cox regression analyses were employed to assess the independent prognostic significance of CXCL12 expression and formulate a nomogram. The expression of CXCL12 in BCa cell lines and clinical tissue samples was validated using enzymelinked immunosorbent assays(ELISA) and immunohistochemistry(IHC).Results: While transcriptional expression of CXCL12 exhibited a decrease in nearly all tumor tissues, CXCL12 methylation expression was notably increased in BCa tissues. Single-cell RNA analysis highlighted tissue stem cells and endothelial cells as the primary sources expressing CXCL12. Abnormal CXCL12 expression, based on transcriptional and methylation levels, correlated with various clinical characteristics in BCa patients. Functional analysis indicated enrichment of CXCL12 and its co-expression genes in immune regulation and cell adhesion. The immune landscape analysis unveiled a significant association between CXCL12 expression and M2 macrophages(CD163~+ cells) in BCa tissues. Notably, CXCL12 expression emerged as a potential predictor of immunotherapy response and chemotherapy drug sensitivity in BCa patients.Conclusions: Taken together, these findings suggest aberrant production of CXCL12 in BCa tissues,potentially influencing the treatment responses of affected individuals.

Changes and significance of serum ubiquitin carboxyl-terminal hydrolase L1 and glial fibrillary acidic protein in patients with glioma

BACKGROUND Brain gliomas are malignant tumors with high postoperative recurrence rates.Early prediction of prognosis using specific indicators is of great significance.AIM To assess changes in ubiquitin carboxy-terminal hydrolase L1(UCH-L1)and glial fibrillary acidic protein(GFAP)levels in patients with glioma pre-and postoperatively.METHODS Between June 2018 and June 2021,91 patients with gliomas who underwent surgery at our hospital were enrolled in the glioma group.Sixty healthy volunteers were included in the control group.Serum UCH-L1 and GFAP levels were measured in peripheral blood collected from patients with glioma before and 3 d after surgery.UCH-L1 and GFAP levels in patients with glioma with different clinicopathological characteristics were compared before and after surgery.The patients were followed-up until February 2022.Postoperative glioma recurrence was recorded to determine the serum UCH-L1 and GFAP levels,which could assist in predicting postoperative glioma recurrence.RESULTS UCH-L1 and GFAP levels in patients with glioma decreased significantly 3 d after surgery compared to those before therapy(P<0.05).However,UCH-L1 and GFAP levels in the glioma group were significantly higher than those in the control group before and after surgery(P<0.05).There were no statistically significant differences in preoperative serum UCH-L1 and GFAP levels among patients with glioma according to sex,age,pathological type,tumor location,or number of lesions(P>0.05).Serum UCH-L1 and GFAP levels were significantly lower in the patients with WHO grade I-II tumors than in those with gradeⅢ-IV tumors(P<0.05).Serum UCH-L1 and GFAP levels were lower in the patients with tumor diameter≤5 cm than in those with diameter>5 cm,in which the differences were statistically significant(P<0.05).Glioma recurred in 22 patients.The preoperative and 3-d postoperative serum UCH-L1 and GFAP levels were significantly higher in the recurrence group than these in the non-recurrence group(P<0.05).Receiver operating characteristic curves were plotted.The areas under the curves of preoperative serum UCH-L1 and GFAP levels for predicting postoperative glioma recurrence were 0.785 and 0.775,respectively.However,the efficacy of serum UCH-L1 and GFAP levels 3 d after surgery in predicting postoperative glioma recurrence was slightly lower compared with their preoperative levels.CONCLUSION UCH-L1 and GFAP efficiently reflected the development and recurrence of gliomas and could be used as potential indicators for the recurrence and prognosis of glioma.

The Significance and Application of the Introduction of Western Culture in College English Teaching

With the development and reform of China’s education,it is important for college English teachers to introduce western culture in the daily teaching process,and to improve the humanistic quality of college students.This paper discusses the significance of introducing western culture,and puts forward some countermeasures based on teaching experience,in order to provide some references for the application of the introduction of western culture in college English teaching.

Selection of Surgical Approach and Clinical Significance of Lower Cervical Spine Injuries Guided by SLIC Scoring System

Objective: To explore the feasibility and clinical significance of surgical approach selection for cervical spine injury guided by SLIC scoring system. Methods: The clinical data of 75 patients with lower cervical injury surgery from January 2020 to November 2022 were retrospectively analyzed, including 48 males and 27 females. Age: 28 - 65 years old. Causes of injury: 39 cases of traffic accidents, 15 cases of ice and snow sports, 12 cases of falling from high places, 9 cases of heavy objects. There were 12 cases of C3-4, 33 cases of C4-5, 21 cases of C5-6, and 9 cases of C6-7. Time from injury to medical treatment: 4 h - 2 d. Cervical spine X-ray, MRI, MDCT examination and preoperative SLIC score were performed on admission. Anterior approach was performed by subtotal cervical vertebrae resection or discectomy, titanium Cage or cage supported bone grafting and anterior titanium plate fixation. Posterior approach was performed with cervical laminoplasty, lateral mass or pedicle screw fixation and fusion. The combined anterior-posterior operation was performed by the anterior methods+ posterior methods. The time from injury to surgery is 12 h to 3 d. The function before and after operation was evaluated by JOA efficacy evaluation criteria. The correlation between the three surgical approaches and postoperative efficacy and SLIC score was compared. SPSS 22.0 software was used for statistical analysis of the data. Results: In this group of 75 patients, 32 cases of anterior operation, 22 cases of posterior operation and 21 cases of combined operation were followed up for no less than 12 months. There was no significant difference in age, gender, injury cause, injury segment, time from injury to treatment, and time from injury to operation among the three surgical approaches, which were comparable. The SLIC scores of mild, moderate and severe injuries of anterior surgery, posterior surgery and combined anterior and posterior surgery, They were (5.26 ± 1.24, 5.86 ± 1.67, 8.25 ± 0.21), (5.57 ± 1.43, 5.99 ± 1.85, 9.00 ± 0.25), (0, 5.98 ± 0.33, 9.44 ± 0.34), respectively. By comparing the SLIC scores and JOA scores of anterior surgery and posterior surgery, there was no difference in SLIC scores and JOA scores between the two groups for mild and moderate injuries (P > 0.05). However, the JOA scores at 3 months, 6 months and 12 months after surgery were different from those before surgery, and the postoperative efficacy and JOA scores were significantly improved (P & lt;0.05), indicating that the two surgical methods had the same therapeutic effect, that is, anterior or posterior surgery could be used to treat mild or moderate injuries (P > 0.05). There were differences in SLIC scores among the three surgical approaches for severe injury (P 0.05). The postoperative efficacy and JOA score of combined anterior-posterior approach were significantly improved compared with those before operation (P Conclusion: SLIC score not only provides accurate judgment for conservative treatment or surgical treatment of cervical spine injury, but also provides evidence-based medical basis and reference value for the selection of surgical approach and surgical method. According to the SLIC score, the surgical approach is safe and feasible. When the SLIC score is 4 - 7, anterior surgery is selected for type A injury, and posterior surgery is selected for type B injury. When the SLIC score is ≥8, combined anterior-posterior surgery should be selected. It is of great significance for clinical formulation of precision treatment strategy.

Detection and Clinical Significance of Th17/Treg Cell-Related Factors in Patients with Gestational Diabetes Mellitus

Objective:To investigate the detection of Th17/Treg cell-related factors in patients with gestational diabetes mellitus(GDM)and its clinical significance.Methods:In this study,a retrospective cohort research method was used to collect the clinical data of 42 patients who were hospitalized in the Affiliated Hospital of Hebei University and received the diagnosis of GDM from January 2018 to December 2022,as well as 42 patients with normal pregnancies during the same period.The Th17/Treg expression levels and metabolism-related indexes in the peripheral blood of patients were detected by radioimmunoassay.Results:The relative expression of Th17 in the serum of patients in the GDM group was significantly higher than that of the control group,and the level of Treg was significantly lower than that of the control group(P<0.05);the levels of FBG,FINS,2hBG,TC,TG and HOMA-IR of the patients in the GDM group were significantly higher than that of the control group,and the level of HOMA-βwas significantly lower than that of the control group(P<0.05).Conclusion:The imbalance of the Th17/Treg cell ratio in patients with GDM may be related to their disease progression and prognosis,providing new ideas and strategies for the clinical treatment of GDM.

Research on the Significance and Problems of Heroes in the Textbook

A large number texts depicting heroes have been compiled in the ministry edition of Chinese textbooks in junior high school,such as Deng Jiaxian,a scientist who has ardent love for the motherland and is fearless of difficulties and dangers;Wen Yiduo,a patriot who is devoted to study and has a strong sense of righteousness;Ye Shengtao,a scholar who is noted for his meticulous scholarship and attends to everything personally;Alizer Buffy,an unknown old man who is devoted to tree-planting in obscurity,and so on.The analysis,understanding and reading of these heroic stories and the interpretation of the significance and value of the selection of heroic images into Chinese textbooks are conducive to grasping the core quality of Chinese courses and improving the teaching of heroic images;inheriting and carrying forward the fine civilization and historical and cultural traditions of mankind,and establishing national cultural self-confidence and pride;perfecting the value system of educators and empowering students to grow healthily;guiding teenagers with immature values to establish healthy and upward values.

习近平文化思想的内涵、特征与核心要义

习近平文化思想是新时代党领导宣传思想文化建设经验的理论总结与思想提升,极大丰富和发展了马克思主义文化理论,在党的文化事业发展史上具有里程碑意义。从内涵看,习近平文化思想是以文化使命为统领,由文化传承、文化创新、文化权益、文化共识、文化引领等方面构成的完备理论体系。从特征看,习近平文化思想具有鲜明的科学性、人民性、实践性、发展性,不仅体现了习近平文化思想的本质,而且展现了习近平文化思想的理论形象。从核心要义看,习近平文化思想主要围绕保障文化安全、坚定文化自信、建设文化强国、增强文化影响等价值目标为新时代宣传思想文化建设提供思想武器和行动指南,为以中国式现代化全面推进中华民族伟大复兴坚定信念、振奋人心、凝聚力量。

从东盟到“东盟世界”:东南亚地区秩序构建的全球意义

当今世界,东盟面临的内外部环境发生新的变化,大国竞争势能持续增加,东盟致力于打造的包容性地区秩序同样处于正增长态势。回顾东南亚地区秩序的构建历程,东盟从被动参与者逐渐演变成为地区秩序塑造者,形成了“东盟世界”的空间形态与理论雏形。“东盟世界”的兴起不是凭空产生,亦非东盟纯粹自发性的结果,而是东盟国家之间、东盟与大国、东盟与全球三大维度的复杂系统合成。“东盟世界”在认知层面来源于东盟对内外部世界的体悟与反思,在实践层面来源于东盟国家之间以及东盟与外部世界互动的经验逻辑。“东盟世界”不是单一静态概念,而是动态的概念集合,可以从宏观层面展现东盟建立的跨区域全球网络的搭建过程,为世界政治呈现动态的东南亚区域概念系谱图变迁,也为“全球南方”参与国际秩序构建提供范例。

川东地区龙潭组页岩岩性序列及勘探意义

川东地区龙潭组具有较大的页岩气勘探前景,该地层沉积于海陆过渡环境,沉积相变化快,岩性复杂,存在难以通过常规的矿物成分方法划分岩相以及当前岩相划分尚不精确的问题,制约了该地区龙潭组页岩有利岩相带识别及勘探。本文基于岩心观察、野外剖面实测和薄片鉴定,结合钻井的泥地比、单层岩性厚度,建立了川东地区龙潭组7种特征岩性组合模式(泥页岩型、富泥含砂型、富泥含灰型、灰泥互层型、富灰含泥型、致密灰岩型和火成岩型);综合TOC、孔隙度、含气性、脆性指数等页岩储层特征参数,明确了不同岩性组合在龙潭组各段的平面分布规律。研究表明,纵向上优势岩性组合主要为龙潭一段富泥含灰型和泥页岩型,龙潭二段主要为泥页岩型、灰泥互层型和富泥含灰型。平面上龙潭一段优势岩性组合富泥含灰型主要分布在开州—云阳一带,泥页岩型主要分布在重庆—綦江一带;龙潭二段优势岩性组合泥页岩型分布在巴南—綦江一带,灰泥互层型分布在达州一带,富泥含灰型分布在万州—梁平—石柱一带。该项研究成果为川东地区龙潭组页岩气勘探提供了重要依据。

绿色加工技术在农业机械制造中的应用

随着现代化农业的快速发展,农业机械需求量日益增加。在国家“节能减排”“碳中和”“碳达峰”的政策要求下,绿色加工技术是现代化农业机械生产发展的新方向。该文通过介绍绿色加工技术的概念和意义,说明农业机械制造中利用绿色加工技术的作用,从原料、加工方式、切削技术等角度出发,阐述绿色加工技术在农业机械制造中的具体应用,并进行展望,为绿色加工技术在农业机械制造的发展提供一定的思路。

凶险性前置胎盘MRI表现及诊断意义

目的探讨凶险性前置胎盘(PPP)核磁共振(MRI)表现及诊断意义。方法回顾性分析67例前置胎盘患者资料,术前均接受MRI检查,经剖宫产术和病理确诊,分析MRI诊断PPP和伴有胎盘植入的诊断效能,观察PPP合并胎盘植入的不同分型诊断结果。结果手术病理诊断PPP患者有60例,非凶险性前置胎盘(nPPP)患者有7例,PPP并发胎盘植入有59例,“金标准”以手术病理诊断结果为准,分析结果显示,MRI诊断PPP的阳性预测值最高,可达96.43%,其次灵敏度可达90.00%%,特异度、精确率则在71.43%、88.06%,阴性预测值最低,为45.45%;MRI诊断PPP并发胎盘植入的阳性预测值最高,可达97.87%,其次特异度可达87.50%,灵敏度、精确率则在77.97%、79.10%,阴性预测值最低,为35.00%;以手术病理诊断PPP合并胎盘植入结果为金标准,MRI的诊断正确率为79.66%,其中粘黏型、植入型及穿透型胎盘植入的诊断正确率分别为50.00%、87.10%及100.00%。结论术前MRI诊断PPP的诊断价值高,能正确评估PPP伴有胎盘植入程度,充分评估胎盘组织与子宫肌层的关系,为产前检查和制定适合治疗方案提供有效信息。