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Clinical efficacy and mechanism study of mid-frequency anti-snoring device in treating moderate obstructive sleep apnea-hypopnea syndrome
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作者 Bao Qian Zhan-Jun Chen +3 位作者 Yong-Sheng Wang Xiao-Yan Hu Xiao-Biao Hu Yong-Hua Zheng 《World Journal of Clinical Cases》 SCIE 2024年第5期942-950,共9页
BACKGROUND Obstructive sleep apnea-hypopnea syndrome(OSAHS)is primarily caused by airway obstruction due to narrowing and blockage in the nasal and nasopha-ryngeal,oropharyngeal,soft palate,and tongue base areas.The m... BACKGROUND Obstructive sleep apnea-hypopnea syndrome(OSAHS)is primarily caused by airway obstruction due to narrowing and blockage in the nasal and nasopha-ryngeal,oropharyngeal,soft palate,and tongue base areas.The mid-frequency anti-snoring device is a new technology based on sublingual nerve stimulation.Its principle is to improve the degree of oropharyngeal airway stenosis in OSAHS patients under mid-frequency wave stimulation.Nevertheless,there is a lack of clinical application and imaging evidence.METHODS We selected 50 patients diagnosed with moderate OSAHS in our hospital between July 2022 and August 2023.They underwent a 4-wk treatment regimen involving the mid-frequency anti-snoring device during nighttime sleep.Following the treatment,we monitored and assessed the sleep apnea quality of life index and Epworth Sleepiness Scale scores.Additionally,we performed computed tomo-graphy scans of the oropharynx in the awake state,during snoring,and while using the mid-frequency anti-snoring device.Cross-sectional area measurements in different states were taken at the narrowest airway point in the soft palate posterior and retrolingual areas.RESULTS Compared to pretreatment measurements,patients exhibited a significant reduction in the apnea-hypopnea index,the percentage of time with oxygen saturation below 90%,snoring frequency,and the duration of the most prolonged apnea event.The lowest oxygen saturation showed a notable increase,and both sleep apnea quality of life index and Epworth Sleepiness Scale scores improved.Oropharyngeal computed tomography scans revealed that in OSAHS patients cross-sectional areas of the oropharyngeal airway in the soft palate posterior area and retrolingual area decreased during snoring compared to the awake state.Conversely,during mid-frequency anti-snoring device treatment,these areas increased compared to snoring.CONCLUSION The mid-frequency anti-snoring device demonstrates the potential to enhance various sleep parameters in patients with moderate OSAHS,thereby improving their quality of life and reducing daytime sleepiness.These therapeutic effects are attributed to the device’s ability to ameliorate the narrowing of the oropharynx in OSAHS patients. 展开更多
关键词 Mid-frequency anti-snoring device Obstructive sleep apnea-hypopnea syndrome Sleep monitoring Oropharyngeal computed tomography Curative effect
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Twin-block阻鼾器在老年阻塞性睡眠呼吸暂停低通气综合征合并冠心病患者中的应用效果 被引量:2
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作者 李小波 贺红芳 《临床医学研究与实践》 2020年第2期48-49,70,共3页
目的探究Twin-block阻鼾器在老年阻塞性睡眠呼吸暂停低通气综合征合并冠心病患者中的应用效果。方法选取2015年1月至2018年12月我院收治的老年阻塞性睡眠呼吸暂停低通气综合征合并冠心病患者95例作为研究对象,根据治疗方法不同将其分为... 目的探究Twin-block阻鼾器在老年阻塞性睡眠呼吸暂停低通气综合征合并冠心病患者中的应用效果。方法选取2015年1月至2018年12月我院收治的老年阻塞性睡眠呼吸暂停低通气综合征合并冠心病患者95例作为研究对象,根据治疗方法不同将其分为试验组(48例)与对照组(47例)。试验组使用Twin-block阻鼾器治疗,对照组使用Silensor阻鼾器治疗。观察两组呼吸紊乱指数、低通气指数、呼吸暂停指数、血氧饱和度、上气道截面积和肿瘤坏死因子水平。结果治疗后3个月,两组呼吸紊乱指数、低通气指数、呼吸暂停指数和肿瘤坏死因子水平均降低,且试验组低于对照组(P<0.05);治疗后3个月,两组血氧饱和度和上气道截面积均提高,且试验组高于对照组(P<0.05)。结论老年阻塞性睡眠呼吸暂停低通气综合征合并冠心病患者运用Twin-block阻鼾器治疗不仅有利于改善呼吸暂停、呼吸紊乱等症状,更有利于提升上气道横截面积与血氧饱和度,对改善缺血、缺氧的心肌细胞有重要作用,值得推广。 展开更多
关键词 Twin-block阻鼾器 阻塞性睡眠呼吸暂停低通气综合征 冠心病 silensor阻鼾器 呼吸暂停指数
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