To ensure a safe and stable CO_(2)storage,pressure responses at an observation well are expected to be an important and useful field monitoring item to estimate the CO_(2)storage behaviors and the aquifer parameters d...To ensure a safe and stable CO_(2)storage,pressure responses at an observation well are expected to be an important and useful field monitoring item to estimate the CO_(2)storage behaviors and the aquifer parameters during and after injecting CO_(2),because it can detect whether the injected CO_(2)leaks to the ground surface or the bottom of the sea.In this study,pressure responses were simulated to present design factors such as well location and pressure transmitter of the observation well.Numerical simulations on the pressure response and the time-delay from pressure build-up after CO_(2)injection were conducted by considering aquifer parameters and distance from the CO_(2)injection well to an observation well.The measurement resolution of a pressure transmitter installed in the observation well was presented based on numerical simulation results of the pressure response against pressure build-up at the injection well and CO_(2)plume front propagations.Furthermore,the pressure response at an observation well was estimated by comparing the numerical simulation results with the curve of CO_(2)saturation and relative permeability.It was also suggested that the analytical solution can be used for the analysis of the pressure response tendency using pressure build-up and dimensionless parameters of hydraulic diffusivity.Thus,a criterion was established for selecting a pressure transducer installed at an observation well to monitor the pressure responses with sufficient accuracy and resolution,considering the distance from the injection well and the pressure build-up at the injection well,for future carbon capture and storage(CCS)projects.展开更多
Resonably good agreement among the photoluminescence,absorption,in-plane photocurrent and theoretical calculation demonstrates the effect of GaAs barrier width on the strain in In_(0.20)Ga_(0.80)As/GaAs single quantum...Resonably good agreement among the photoluminescence,absorption,in-plane photocurrent and theoretical calculation demonstrates the effect of GaAs barrier width on the strain in In_(0.20)Ga_(0.80)As/GaAs single quantum wells.The strain of each sample has been deduced.展开更多
BACKGROUND Transforming growth factor-β(TGF-β)superfamily plays an important role in tumor progression and metastasis.Activin A receptor type 1C(ACVR1C)is a TGF-βtype I receptor that is involved in tumorigenesis th...BACKGROUND Transforming growth factor-β(TGF-β)superfamily plays an important role in tumor progression and metastasis.Activin A receptor type 1C(ACVR1C)is a TGF-βtype I receptor that is involved in tumorigenesis through binding to dif-ferent ligands.AIM To evaluate the correlation between single nucleotide polymorphisms(SNPs)of ACVR1C and susceptibility to esophageal squamous cell carcinoma(ESCC)in Chinese Han population.METHODS In this hospital-based cohort study,1043 ESCC patients and 1143 healthy controls were enrolled.Five SNPs(rs4664229,rs4556933,rs77886248,rs77263459,rs6734630)of ACVR1C were assessed by the ligation detection reaction method.Hardy-Weinberg equilibrium test,genetic model analysis,stratified analysis,linkage disequi-librium test,and haplotype analysis were conducted.RESULTS Participants carrying ACVR1C rs4556933 GA mutant had significantly decreased risk of ESCC,and those with rs77886248 TA mutant were related with higher risk,especially in older male smokers.In the haplotype analysis,ACVR1C Trs4664229Ars4556933Trs77886248Crs77263459Ars6734630 increased risk of ESCC,while Trs4664229Grs4556933Trs77886248Crs77263459Ars6734630 was associated with lower susceptibility to ESCC.CONCLUSION ACVR1C rs4556933 and rs77886248 SNPs were associated with the susceptibility to ESCC,which could provide a potential target for early diagnosis and treatment of ESCC in Chinese Han population.展开更多
The Burris Gravity MeterTM manufactured by ZLS Corporation, Austin/Texas, USA, is based on the in- vention of L^R (L. LaCoste and A. Romberg): The ZLS (zero-length spring). A digital feedback system (range of ab...The Burris Gravity MeterTM manufactured by ZLS Corporation, Austin/Texas, USA, is based on the in- vention of L^R (L. LaCoste and A. Romberg): The ZLS (zero-length spring). A digital feedback system (range of about 50 mGal) is used to null the beam. Now, more than 120 gravity meters of this make exist worldwide and are used successfully in exploration, volcanology, geodetic work and surveying. The sensor is made of the well-known (L&R) metal-alloy zero-length spring providing a low drift characteristic. The drifts observed are comparable to L&R gravimeters and are less than 0.3 mGal per month, which is much lower than the drifts known for the fused quartz sensors. The dial is calibrated every 50 regal over the entire 7000 mGal meter range. Since the gravity value is determined at these points, there are no periodic errors. By a fourth heater circuit temperature effects are totally avoided. The gravity meter is controlled via Bluetoothce either to a handheld computer (tablet) or a notebook computer. The feedback responds with high stability and accuracy. The hulling of the beam is controlled by the UltraGravTM control system which incorporates an inherently linear PWM (pulse-width modulated) electrostatic feedback system. In order to improve the handling of the gravimeter we have developed two Windows based programs: AGESfield for single measurements and AGEScont for continuous readings.展开更多
The planetary boundary layer turbulence and moist convection parameterizations have been modified recently in the NASA Goddard Institute for Space Studies (GISS) Model E2 atmospheric general circulation model (GCM;...The planetary boundary layer turbulence and moist convection parameterizations have been modified recently in the NASA Goddard Institute for Space Studies (GISS) Model E2 atmospheric general circulation model (GCM; post-CMIP5, hereafter P5). In this study, single column model (SCM_P5) simulated cloud fractions (CFs), cloud liquid water paths (LWPs) and precipitation were compared with Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) groundbased observations made during the period 2002-08. CMIP5 SCM simulations and GCM outputs over the ARM SGP region were also used in the comparison to identify whether the causes of cloud and precipitation biases resulted from either the physical parameterization or the dynamic scheme. The comparison showed that the CMIP5 SCM has difficulties in simulating the vertical structure and seasonal variation of low-level clouds. The new scheme implemented in the turbulence parameterization led to significantly improved cloud simulations in P5. It was found that the SCM is sensitive to the relaxation time scale. When the relaxation time increased from 3 to 24 h, SCM_P5-simulated CFs and LWPs showed a moderate increase (10%-20%) but precipitation increased significantly (56%), which agreed better with observations despite the less accurate atmospheric state. Annual averages among the GCM and SCM simulations were almost the same, but their respective seasonal variations were out of phase. This suggests that the same physical cloud parameterization can generate similar statistical results over a long time period, but different dynamics drive the differences in seasonal variations. This study can potentially provide guidance for the further development of the GISS model.展开更多
Single caesium atoms in a large-magnetic-gradient vapour-cell magneto-optical trap have been identified. The trapping of individual atoms is marked by the steps in fluorescence signal corresponding to the capture or l...Single caesium atoms in a large-magnetic-gradient vapour-cell magneto-optical trap have been identified. The trapping of individual atoms is marked by the steps in fluorescence signal corresponding to the capture or loss of single atoms. The typical magnetic gradient is about 29 mT/cm, which evidently reduces the capture rate of magneto-optical trap.展开更多
The vertical distribution of single scattering albedos (SSAs) of Asian dust mixed with pollutants was derived using the multi-wavelength Raman lidar observation system at Gwangju (35.10°N,126.53°E).Verti...The vertical distribution of single scattering albedos (SSAs) of Asian dust mixed with pollutants was derived using the multi-wavelength Raman lidar observation system at Gwangju (35.10°N,126.53°E).Vertical profiles of both backscatter and extinction coefficients for dust and non-dust aerosols were extracted from a mixed Asian dust plume using the depolarization ratio from lidar observations.Vertical profiles of backscatter and extinction coefficients of non-dust particles were input into an inversion algorithm to retrieve the SSAs of non-dust aerosols.Atmospheric aerosol layers at different heights had different light-absorbing characteristics.The SSAs of non-dust particles at each height varied with aerosol type,which was either urban/industrial pollutants from China transported over long distances at high altitude,or regional/local pollutants from the Korean peninsula.Taking advantage of independent profiles of SSAs of non-dust particles,vertical profiles of SSAs of Asian dust mixed with pollutants were estimated for the first time,with a new approach suggested in this study using an empirical determination of the SSA of pure dust.The SSAs of the Asian dust-pollutants mixture within the planetary boundary layer (PBL) were in the range 0.88-0.91,while the values above the PBL were in the range 0.76-0.87,with a very low mean value of 0.76 ± 0.05.The total mixed dust plume SSAs in each aerosol layer were integrated over height for comparison with results from the Aerosol Robotics Network (AERONET) measurements.Values of SSA retrieved from lidar observations of 0.92 ± 0.01 were in good agreement with the results from AERONET measurements.展开更多
This paper studies the exciton-longitudinal-optical-phonon coupling in InGaN/GaN single quantum wells with various cap layer thicknesses by low temperature photoluminescence (PL) measurements. With increasing cap la...This paper studies the exciton-longitudinal-optical-phonon coupling in InGaN/GaN single quantum wells with various cap layer thicknesses by low temperature photoluminescence (PL) measurements. With increasing cap layer thickness, the PL peak energy shifts to lower energy and the coupling strength between the exciton and longitudinal- optical (LO) phonon, described by Huang-Rhys factor, increases remarkably due to an enhancement of the internal electric field. With increasing excitation intensity, the zero-phonon peak shows a blueshift and the Huang-Rhys factor decreases. These results reveal that there is a large built-in electric field in the well layer and the exciton-LO-phonon coupling is strongly affected by the thickness of the cap layer.展开更多
Since the oil production of single well in water flooding reservoir varies greatly and is hard to predict, an oil production prediction method of single well based on temporal convolutional network(TCN) is proposed an...Since the oil production of single well in water flooding reservoir varies greatly and is hard to predict, an oil production prediction method of single well based on temporal convolutional network(TCN) is proposed and verified. This method is started from data processing, the correspondence between water injectors and oil producers is determined according to the influence radius of the water injectors, the influence degree of a water injector on an oil producer in the month concerned is added as a model feature, and a Random Forest(RF) model is built to fill the dynamic data of water flooding. The single well history is divided into 4 stages according to its water cut, that is, low water cut, middle water cut, high water cut and extra-high water cut stages. In each stage, a TCN based prediction model is established, hyperparameters of the model are optimized by the Sparrow Search Algorithm(SSA). Finally, the models of the 4 stages are integrated into one whole-life model of the well for production prediction. The application of this method in Daqing Oilfield, NE China shows that:(1) Compared with conventional data processing methods, the data obtained by this processing method are more close to the actual production, and the data set obtained is more authentic and complete.(2) The TCN model has higher prediction accuracy than other 11 models such as Long Short Term Memory(LSTM).(3) Compared with the conventional full-life-cycle models, the model of integrated stages can significantly reduce the error of production prediction.展开更多
Utilizing supported single atoms as catalysts presents an opportunity to reduce the usage of critical raw materials such as platinum,which are essential for electrochemical reactions such as hydrogen oxidation reactio...Utilizing supported single atoms as catalysts presents an opportunity to reduce the usage of critical raw materials such as platinum,which are essential for electrochemical reactions such as hydrogen oxidation reaction(HOR).Herein,we describe the synthesis of a Pt single electrocatalyst inside single-walled carbon nanotubes(SWCNTs)via a redox reaction.Characterizations via electron microscopy,X-ray photoelectron microscopy,and X-ray absorption spectroscopy show the single-atom nature of the Pt.The electrochemical behavior of the sample to hydrogen and oxygen was investigated using the advanced floating electrode technique,which minimizes mass transport limitations and gives a thorough insight into the activity of the electrocatalyst.The single-atom samples showed higher HOR activity than state-of-the-art 30%Pt/C while almost no oxygen reduction reaction activity in the proton exchange membrane fuel cell operating range.The selective activity toward HOR arose as the main fingerprint of the catalyst confinement in the SWCNTs.展开更多
The resonant excitation is used to generate photo-excited carriers in quantum wells to observe the process of the carriers transportation by comparing the photoluminescence results between quantum wells with and witho...The resonant excitation is used to generate photo-excited carriers in quantum wells to observe the process of the carriers transportation by comparing the photoluminescence results between quantum wells with and without a p-n junction. It is observed directly in experiment that most of the photo-excited carriers in quantum wells with a p-n junction escape from quantum wells and form photoeurrent rather than relax to the ground state of the quantum wells. The photo absorption coei^cient of multiple quantum wells is also enhanced by a p-n junction. The results pave a novel way for solar cells and photodetectors making use of low-dimensional structure.展开更多
Single-atom catalysts(SACs)have gained substantial attention because of their exceptional catalytic properties.However,the high surface energy limits their synthesis,thus creating significant challenges for further de...Single-atom catalysts(SACs)have gained substantial attention because of their exceptional catalytic properties.However,the high surface energy limits their synthesis,thus creating significant challenges for further development.In the last few years,metal–organic frameworks(MOFs)have received significant consideration as ideal candidates for synthesizing SACs due to their tailorable chemistry,tunable morphologies,high porosity,and chemical/thermal stability.From this perspective,this review thoroughly summarizes the previously reported methods and possible future approaches for constructing MOF-based(MOF-derived-supported and MOF-supported)SACs.Then,MOF-based SAC's identification techniques are briefly assessed to understand their coordination environments,local electronic structures,spatial distributions,and catalytic/electrochemical reaction mechanisms.This review systematically highlights several photocatalytic and electrocatalytic applications of MOF-based SACs for energy conversion and storage,including hydrogen evolution reactions,oxygen evolution reactions,O_(2)/CO_(2)/N_(2) reduction reactions,fuel cells,and rechargeable batteries.Some light is also shed on the future development of this highly exciting field by highlighting the advantages and limitations of MOF-based SACs.展开更多
In this paper, a regression method of estimation has been used to derive the mean estimate of the survey variable using simple random sampling without replacement in the presence of observational errors. Two covariate...In this paper, a regression method of estimation has been used to derive the mean estimate of the survey variable using simple random sampling without replacement in the presence of observational errors. Two covariates were used and a case where the observational errors were in both the survey variable and the covariates was considered. The inclusion of observational errors was due to the fact that data collected through surveys are often not free from errors that occur during observation. These errors can occur due to over-reporting, under-reporting, memory failure by the respondents or use of imprecise tools of data collection. The expression of mean squared error (MSE) based on the obtained estimator has been derived to the first degree of approximation. The results of a simulation study show that the derived modified regression mean estimator under observational errors is more efficient than the mean per unit estimator and some other existing estimators. The proposed estimator can therefore be used in estimating a finite population mean, while considering observational errors that may occur during a study.展开更多
This paper investigates the temperature dependence of single-event transients(SETs) in 90-nm complementary metat-oxide semiconductor(CMOS) dual-well and triple-well negative metal-oxide semiconductor field-effect ...This paper investigates the temperature dependence of single-event transients(SETs) in 90-nm complementary metat-oxide semiconductor(CMOS) dual-well and triple-well negative metal-oxide semiconductor field-effect transistors(NMOSFETs).Technology computer-aided design(TCAD) three-dimensional(3D) simulations show that the drain current pulse duration increases from 85 ps to 245 ps for triple-well but only increases from 65 ps to 98 ps for dual-well when the temperature increases from-55℃ to 125℃,which is closely correlated with the NMOSFET sources.This reveals that the pulse width increases with temperature in dual-well due to the weakening of the anti-amplification bipolar effect while increases with temperature in triple-well due to the enhancement of the bipolar amplification.展开更多
The dynamic behaviors of the keyhole and weld pool are coupled together in plasma arc welding, and the geometric variations of both the keyhole and the weld pool determine the weld quality. It is of great significance...The dynamic behaviors of the keyhole and weld pool are coupled together in plasma arc welding, and the geometric variations of both the keyhole and the weld pool determine the weld quality. It is of great significance to simultaneously sense and monitor the keyhole and the weld pool behaviors by using a single low-cost vision sensor in plasma arc welding process. In this study, the keyhole and weld pool were observed and measured under different levels of welding current by using the near infrared sensing technology and the charge coupled device (CCD) sensing system. The shapes and relative position of weld pool and keyhole under different conditions were compared and analyzed. The observation results lay solid foundation for controlling weld quality and understanding the underlying process mechanisms.展开更多
As life expectancy increases,heart conditions,and especially acute coronary syndromes(ACS),are becoming a greater health issue.[1-3]Accordingly,the number of elderly patients in registries of myocardial infarction,is ...As life expectancy increases,heart conditions,and especially acute coronary syndromes(ACS),are becoming a greater health issue.[1-3]Accordingly,the number of elderly patients in registries of myocardial infarction,is increasingly growing.[4,5]However,elderly patients are less likely to be treated with invasive strategy compared to younger patients,despite their intrinsic greater risk.[6,7]Several reports have described how quality initiatives improve treatment of ST elevation myocardial infarction(STEMI).展开更多
The influence of the width of a lattice-matched A10.82In0.18N/GaN single quantum well (SQW) on the absorption coefficients and wavelength of the intersubband transition (ISBT) has been investigated by solving the ...The influence of the width of a lattice-matched A10.82In0.18N/GaN single quantum well (SQW) on the absorption coefficients and wavelength of the intersubband transition (ISBT) has been investigated by solving the Schr5dinger and Poisson equations self-consistently. The wavelength of 1-2 ISBT increases with L, the thickness of the single quantum well, ranging from 2.88 ~m to 3.59 ~.m. The absorption coefficients of 1-2 ISBT increase with L at first and then decrease with L, with a maximum when L is equal to 2.6 nm. The wavelength of 1-3 ISBT decreases with L at first and then increases with L, with a minimum when L is equal to 4 nm, ranging from approximately 2.03 p^m to near 2.11 p.m. The absorption coefficients of 1-3 ISBT decrease with L. The results indicate that mid-infrared can be realized by the A10.s2In0.1sN/GaN SQW. In addition, the wavelength and absorption coefficients of ISBT can be adjusted by changing the width of the SQW.展开更多
Traditional fluid production profile logging is not usually suitable for heavy-viscous crude oil wells.Biodegradation of heavy oil can lead to the loss of n-alkanes,and the use of chromatogram fingerprint techniques i...Traditional fluid production profile logging is not usually suitable for heavy-viscous crude oil wells.Biodegradation of heavy oil can lead to the loss of n-alkanes,and the use of chromatogram fingerprint techniques in studying the production contributions of single layers in heavy oil commingled wells has limitations.However,aromatic compounds are relatively well preserved.We took the heavy oil commingled wells of small layers NG55 and NG61 in the ninth area of the Gudong oil field as examples.Based on the principle of chromatography,the whole-oil GC-MS was used,and the aromatic parameters which have a strongly linear relationship with the ratio of mixed two end member oils were verified and selected in laboratory.Studies showed that the ratio of (1,4,6-+ 2,3,6-trimethylnaphthalene) to 1,2,5-trimethylnaphthalene has a strongly linear relationship with the ratio of the mixed two end member oils (R2=0.992).The oil contributions from single layers NG55 and NG61 in six commingled heavy oil wells were calculated using established charts and this relationship.The calculated results are consistent with the results of long period dynamic monitoring and logging interpretation in the study area and can provide a scientific basis for monitoring production performance and hierarchical management of reservoirs.The study provides a new geochemical method for calculation of the contributions of single layers in heavy oil commingled wells when conventional fluid production profile logging is not suitable.展开更多
We demonstrated a scheme of phase-locked terahertz quantum cascade lasers(THz QCLs)array,with a single-mode pulse power of 108 mW at 13 K.The device utilizes a Talbot cavity to achieve phase locking among five ridge l...We demonstrated a scheme of phase-locked terahertz quantum cascade lasers(THz QCLs)array,with a single-mode pulse power of 108 mW at 13 K.The device utilizes a Talbot cavity to achieve phase locking among five ridge lasers with first-order buried distributed feedback(DFB)grating,resulting in nearly five times amplification of the single-mode power.Due to the optimum length of Talbot cavity depends on wavelength,the combination of Talbot cavity with the DFB grating leads to better power amplification than the combination with multimode Fabry-Perot(F-P)cavities.The Talbot cavity facet reflects light back to the ridge array direction and achieves self-imaging in the array,enabling phase-locked operation of ridges.We set the spacing between adjacent elements to be 220μm,much larger than the free-space wavelength,ensuring the operation of the fundamental supermode throughout the laser's dynamic range and obtaining a high-brightness far-field distribution.This scheme provides a new approach for enhancing the single-mode power of THz QCLs.展开更多
We derived the properties of the terrestrial magnetopause(MP)from two modeling approaches,one global–fluid,the other local–kinetic,and compared the results with data collected in situ by the Magnetospheric Multiscal...We derived the properties of the terrestrial magnetopause(MP)from two modeling approaches,one global–fluid,the other local–kinetic,and compared the results with data collected in situ by the Magnetospheric Multiscale 2(MMS2)spacecraft.We used global magnetohydrodynamic(MHD)simulations of the Earth’s magnetosphere(publicly available from the NASA-CCMC[National Aeronautics and Space Administration–Community Coordinated Modeling Center])and local Vlasov equilibrium models(based on kinetic models for tangential discontinuities)to extract spatial profiles of the plasma and field variables at the Earth’s MP.The global MHD simulations used initial solar wind conditions extracted from the OMNI database at the time epoch when the MMS2 observes the MP.The kinetic Vlasov model used asymptotic boundary conditions derived from the same in situ MMS measurements upstream or downstream of the MP.The global MHD simulations provide a three-dimensional image of the magnetosphere at the time when the MMS2 crosses the MP.The Vlasov model provides a one-dimensional local view of the MP derived from first principles of kinetic theory.The MMS2 experimental data also serve as a reference for comparing and validating the numerical simulations and modeling.We found that the MP transition layer formed in global MHD simulations was generally localized closer to the Earth(roughly by one Earth radius)from the position of the real MP observed by the MMS.We also found that the global MHD simulations overestimated the thickness of the MP transition by one order of magnitude for three analyzed variables:magnetic field,density,and tangential speed.The MP thickness derived from the local Vlasov equilibrium was consistent with observations for all three of these variables.The overestimation of density in the Vlasov equilibrium was reduced compared with the global MHD solutions.We discuss our results in the context of future SMILE(Solar wind Magnetosphere Ionosphere Link Explorer)campaigns for observing the Earth’s MP.展开更多
基金We acknowledge the funding support from the Research Fund for the special projects in key fields of Guangdong Universities(Grant No.2021ZDZX4074)the Japan Society for the Promotion of Science(Grant No.JP-20K21163)Scientific Research Fund of Hainan University(Approval No.KYQD(ZR)-22122).
文摘To ensure a safe and stable CO_(2)storage,pressure responses at an observation well are expected to be an important and useful field monitoring item to estimate the CO_(2)storage behaviors and the aquifer parameters during and after injecting CO_(2),because it can detect whether the injected CO_(2)leaks to the ground surface or the bottom of the sea.In this study,pressure responses were simulated to present design factors such as well location and pressure transmitter of the observation well.Numerical simulations on the pressure response and the time-delay from pressure build-up after CO_(2)injection were conducted by considering aquifer parameters and distance from the CO_(2)injection well to an observation well.The measurement resolution of a pressure transmitter installed in the observation well was presented based on numerical simulation results of the pressure response against pressure build-up at the injection well and CO_(2)plume front propagations.Furthermore,the pressure response at an observation well was estimated by comparing the numerical simulation results with the curve of CO_(2)saturation and relative permeability.It was also suggested that the analytical solution can be used for the analysis of the pressure response tendency using pressure build-up and dimensionless parameters of hydraulic diffusivity.Thus,a criterion was established for selecting a pressure transducer installed at an observation well to monitor the pressure responses with sufficient accuracy and resolution,considering the distance from the injection well and the pressure build-up at the injection well,for future carbon capture and storage(CCS)projects.
文摘Resonably good agreement among the photoluminescence,absorption,in-plane photocurrent and theoretical calculation demonstrates the effect of GaAs barrier width on the strain in In_(0.20)Ga_(0.80)As/GaAs single quantum wells.The strain of each sample has been deduced.
基金Supported by The National Natural Science Foundation of China,No.82350127 and No.82241013the Shanghai Natural Science Foundation,No.20ZR1411600+2 种基金the Shanghai Shenkang Hospital Development Center,No.SHDC2020CR4039the Bethune Ethicon Excellent Surgery Foundation,No.CESS2021TC04Xuhui District Medical Research Project of Shanghai,No.SHXH201805.
文摘BACKGROUND Transforming growth factor-β(TGF-β)superfamily plays an important role in tumor progression and metastasis.Activin A receptor type 1C(ACVR1C)is a TGF-βtype I receptor that is involved in tumorigenesis through binding to dif-ferent ligands.AIM To evaluate the correlation between single nucleotide polymorphisms(SNPs)of ACVR1C and susceptibility to esophageal squamous cell carcinoma(ESCC)in Chinese Han population.METHODS In this hospital-based cohort study,1043 ESCC patients and 1143 healthy controls were enrolled.Five SNPs(rs4664229,rs4556933,rs77886248,rs77263459,rs6734630)of ACVR1C were assessed by the ligation detection reaction method.Hardy-Weinberg equilibrium test,genetic model analysis,stratified analysis,linkage disequi-librium test,and haplotype analysis were conducted.RESULTS Participants carrying ACVR1C rs4556933 GA mutant had significantly decreased risk of ESCC,and those with rs77886248 TA mutant were related with higher risk,especially in older male smokers.In the haplotype analysis,ACVR1C Trs4664229Ars4556933Trs77886248Crs77263459Ars6734630 increased risk of ESCC,while Trs4664229Grs4556933Trs77886248Crs77263459Ars6734630 was associated with lower susceptibility to ESCC.CONCLUSION ACVR1C rs4556933 and rs77886248 SNPs were associated with the susceptibility to ESCC,which could provide a potential target for early diagnosis and treatment of ESCC in Chinese Han population.
文摘The Burris Gravity MeterTM manufactured by ZLS Corporation, Austin/Texas, USA, is based on the in- vention of L^R (L. LaCoste and A. Romberg): The ZLS (zero-length spring). A digital feedback system (range of about 50 mGal) is used to null the beam. Now, more than 120 gravity meters of this make exist worldwide and are used successfully in exploration, volcanology, geodetic work and surveying. The sensor is made of the well-known (L&R) metal-alloy zero-length spring providing a low drift characteristic. The drifts observed are comparable to L&R gravimeters and are less than 0.3 mGal per month, which is much lower than the drifts known for the fused quartz sensors. The dial is calibrated every 50 regal over the entire 7000 mGal meter range. Since the gravity value is determined at these points, there are no periodic errors. By a fourth heater circuit temperature effects are totally avoided. The gravity meter is controlled via Bluetoothce either to a handheld computer (tablet) or a notebook computer. The feedback responds with high stability and accuracy. The hulling of the beam is controlled by the UltraGravTM control system which incorporates an inherently linear PWM (pulse-width modulated) electrostatic feedback system. In order to improve the handling of the gravimeter we have developed two Windows based programs: AGESfield for single measurements and AGEScont for continuous readings.
基金supported by the DOE ASR program(Grant No.DESC008468)
文摘The planetary boundary layer turbulence and moist convection parameterizations have been modified recently in the NASA Goddard Institute for Space Studies (GISS) Model E2 atmospheric general circulation model (GCM; post-CMIP5, hereafter P5). In this study, single column model (SCM_P5) simulated cloud fractions (CFs), cloud liquid water paths (LWPs) and precipitation were compared with Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) groundbased observations made during the period 2002-08. CMIP5 SCM simulations and GCM outputs over the ARM SGP region were also used in the comparison to identify whether the causes of cloud and precipitation biases resulted from either the physical parameterization or the dynamic scheme. The comparison showed that the CMIP5 SCM has difficulties in simulating the vertical structure and seasonal variation of low-level clouds. The new scheme implemented in the turbulence parameterization led to significantly improved cloud simulations in P5. It was found that the SCM is sensitive to the relaxation time scale. When the relaxation time increased from 3 to 24 h, SCM_P5-simulated CFs and LWPs showed a moderate increase (10%-20%) but precipitation increased significantly (56%), which agreed better with observations despite the less accurate atmospheric state. Annual averages among the GCM and SCM simulations were almost the same, but their respective seasonal variations were out of phase. This suggests that the same physical cloud parameterization can generate similar statistical results over a long time period, but different dynamics drive the differences in seasonal variations. This study can potentially provide guidance for the further development of the GISS model.
基金Project supported by the National Natural Science Foundation of China (Grant Nos 60578018 and 10434080)the State Key Research Program of China (Grant No 2006CB921102)+2 种基金the Program for New Century Excellent Talents of the Education Ministry, China (Grant No NCET-07-0524)the Specialized Research Fund for the Doctoral Program of China (Grant No 20070108003)the Natural Science Foundation of Shanxi Province, China (Grant No 2007011003)
文摘Single caesium atoms in a large-magnetic-gradient vapour-cell magneto-optical trap have been identified. The trapping of individual atoms is marked by the steps in fluorescence signal corresponding to the capture or loss of single atoms. The typical magnetic gradient is about 29 mT/cm, which evidently reduces the capture rate of magneto-optical trap.
基金funded by the Korea Meteorological Administration Research and Development Program (Grant No.CATER 2012-7080)a National Research Foundation of Korea (NRF) grant funded by the Korean government (MEST) (Grant No.2012R1A1A2002983)the Global Ph.D. Fellowship program sponsored by the National Research Foundation of Korea
文摘The vertical distribution of single scattering albedos (SSAs) of Asian dust mixed with pollutants was derived using the multi-wavelength Raman lidar observation system at Gwangju (35.10°N,126.53°E).Vertical profiles of both backscatter and extinction coefficients for dust and non-dust aerosols were extracted from a mixed Asian dust plume using the depolarization ratio from lidar observations.Vertical profiles of backscatter and extinction coefficients of non-dust particles were input into an inversion algorithm to retrieve the SSAs of non-dust aerosols.Atmospheric aerosol layers at different heights had different light-absorbing characteristics.The SSAs of non-dust particles at each height varied with aerosol type,which was either urban/industrial pollutants from China transported over long distances at high altitude,or regional/local pollutants from the Korean peninsula.Taking advantage of independent profiles of SSAs of non-dust particles,vertical profiles of SSAs of Asian dust mixed with pollutants were estimated for the first time,with a new approach suggested in this study using an empirical determination of the SSA of pure dust.The SSAs of the Asian dust-pollutants mixture within the planetary boundary layer (PBL) were in the range 0.88-0.91,while the values above the PBL were in the range 0.76-0.87,with a very low mean value of 0.76 ± 0.05.The total mixed dust plume SSAs in each aerosol layer were integrated over height for comparison with results from the Aerosol Robotics Network (AERONET) measurements.Values of SSA retrieved from lidar observations of 0.92 ± 0.01 were in good agreement with the results from AERONET measurements.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 60876007 and 10974165)the Research Program of Xiamen Municipal Science and Technology Bureau,China (Grant No. 2006AA03Z110)
文摘This paper studies the exciton-longitudinal-optical-phonon coupling in InGaN/GaN single quantum wells with various cap layer thicknesses by low temperature photoluminescence (PL) measurements. With increasing cap layer thickness, the PL peak energy shifts to lower energy and the coupling strength between the exciton and longitudinal- optical (LO) phonon, described by Huang-Rhys factor, increases remarkably due to an enhancement of the internal electric field. With increasing excitation intensity, the zero-phonon peak shows a blueshift and the Huang-Rhys factor decreases. These results reveal that there is a large built-in electric field in the well layer and the exciton-LO-phonon coupling is strongly affected by the thickness of the cap layer.
基金Major Unified Construction Project of Petro China(2019-40210-000020-02)。
文摘Since the oil production of single well in water flooding reservoir varies greatly and is hard to predict, an oil production prediction method of single well based on temporal convolutional network(TCN) is proposed and verified. This method is started from data processing, the correspondence between water injectors and oil producers is determined according to the influence radius of the water injectors, the influence degree of a water injector on an oil producer in the month concerned is added as a model feature, and a Random Forest(RF) model is built to fill the dynamic data of water flooding. The single well history is divided into 4 stages according to its water cut, that is, low water cut, middle water cut, high water cut and extra-high water cut stages. In each stage, a TCN based prediction model is established, hyperparameters of the model are optimized by the Sparrow Search Algorithm(SSA). Finally, the models of the 4 stages are integrated into one whole-life model of the well for production prediction. The application of this method in Daqing Oilfield, NE China shows that:(1) Compared with conventional data processing methods, the data obtained by this processing method are more close to the actual production, and the data set obtained is more authentic and complete.(2) The TCN model has higher prediction accuracy than other 11 models such as Long Short Term Memory(LSTM).(3) Compared with the conventional full-life-cycle models, the model of integrated stages can significantly reduce the error of production prediction.
基金support from Horizon 2020 program within the ITN FlowcampDZ acknowledges funding from the Wohl Foundation for research for the promotion of UK-Israel research cooperationDZ acknowledges funding from Israel Ministry of Energy(grant#220-11-047).
文摘Utilizing supported single atoms as catalysts presents an opportunity to reduce the usage of critical raw materials such as platinum,which are essential for electrochemical reactions such as hydrogen oxidation reaction(HOR).Herein,we describe the synthesis of a Pt single electrocatalyst inside single-walled carbon nanotubes(SWCNTs)via a redox reaction.Characterizations via electron microscopy,X-ray photoelectron microscopy,and X-ray absorption spectroscopy show the single-atom nature of the Pt.The electrochemical behavior of the sample to hydrogen and oxygen was investigated using the advanced floating electrode technique,which minimizes mass transport limitations and gives a thorough insight into the activity of the electrocatalyst.The single-atom samples showed higher HOR activity than state-of-the-art 30%Pt/C while almost no oxygen reduction reaction activity in the proton exchange membrane fuel cell operating range.The selective activity toward HOR arose as the main fingerprint of the catalyst confinement in the SWCNTs.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11574362,61210014,and 11374340the Innovative Clean-Energy Research and Application Program of Beijing Municipal Science and Technology Commission under Grant No Z151100003515001
文摘The resonant excitation is used to generate photo-excited carriers in quantum wells to observe the process of the carriers transportation by comparing the photoluminescence results between quantum wells with and without a p-n junction. It is observed directly in experiment that most of the photo-excited carriers in quantum wells with a p-n junction escape from quantum wells and form photoeurrent rather than relax to the ground state of the quantum wells. The photo absorption coei^cient of multiple quantum wells is also enhanced by a p-n junction. The results pave a novel way for solar cells and photodetectors making use of low-dimensional structure.
基金support from the Shenzhen Science and Technology Program(No.KQTD20190929173914967,ZDSYS20220527171401003,and JCYJ20200109110416441).
文摘Single-atom catalysts(SACs)have gained substantial attention because of their exceptional catalytic properties.However,the high surface energy limits their synthesis,thus creating significant challenges for further development.In the last few years,metal–organic frameworks(MOFs)have received significant consideration as ideal candidates for synthesizing SACs due to their tailorable chemistry,tunable morphologies,high porosity,and chemical/thermal stability.From this perspective,this review thoroughly summarizes the previously reported methods and possible future approaches for constructing MOF-based(MOF-derived-supported and MOF-supported)SACs.Then,MOF-based SAC's identification techniques are briefly assessed to understand their coordination environments,local electronic structures,spatial distributions,and catalytic/electrochemical reaction mechanisms.This review systematically highlights several photocatalytic and electrocatalytic applications of MOF-based SACs for energy conversion and storage,including hydrogen evolution reactions,oxygen evolution reactions,O_(2)/CO_(2)/N_(2) reduction reactions,fuel cells,and rechargeable batteries.Some light is also shed on the future development of this highly exciting field by highlighting the advantages and limitations of MOF-based SACs.
文摘In this paper, a regression method of estimation has been used to derive the mean estimate of the survey variable using simple random sampling without replacement in the presence of observational errors. Two covariates were used and a case where the observational errors were in both the survey variable and the covariates was considered. The inclusion of observational errors was due to the fact that data collected through surveys are often not free from errors that occur during observation. These errors can occur due to over-reporting, under-reporting, memory failure by the respondents or use of imprecise tools of data collection. The expression of mean squared error (MSE) based on the obtained estimator has been derived to the first degree of approximation. The results of a simulation study show that the derived modified regression mean estimator under observational errors is more efficient than the mean per unit estimator and some other existing estimators. The proposed estimator can therefore be used in estimating a finite population mean, while considering observational errors that may occur during a study.
基金Project supported by the State Key Program of the National Natural Science Foundation of China (Grant No. 60836004)Innovation Foundation for Postgraduate of Hunan Province,China (Grant No. CX2011B026)
文摘This paper investigates the temperature dependence of single-event transients(SETs) in 90-nm complementary metat-oxide semiconductor(CMOS) dual-well and triple-well negative metal-oxide semiconductor field-effect transistors(NMOSFETs).Technology computer-aided design(TCAD) three-dimensional(3D) simulations show that the drain current pulse duration increases from 85 ps to 245 ps for triple-well but only increases from 65 ps to 98 ps for dual-well when the temperature increases from-55℃ to 125℃,which is closely correlated with the NMOSFET sources.This reveals that the pulse width increases with temperature in dual-well due to the weakening of the anti-amplification bipolar effect while increases with temperature in triple-well due to the enhancement of the bipolar amplification.
文摘The dynamic behaviors of the keyhole and weld pool are coupled together in plasma arc welding, and the geometric variations of both the keyhole and the weld pool determine the weld quality. It is of great significance to simultaneously sense and monitor the keyhole and the weld pool behaviors by using a single low-cost vision sensor in plasma arc welding process. In this study, the keyhole and weld pool were observed and measured under different levels of welding current by using the near infrared sensing technology and the charge coupled device (CCD) sensing system. The shapes and relative position of weld pool and keyhole under different conditions were compared and analyzed. The observation results lay solid foundation for controlling weld quality and understanding the underlying process mechanisms.
基金The author would like to thank Jani Y Perdomo Garces for her efforts checking grammar and spelling.
文摘As life expectancy increases,heart conditions,and especially acute coronary syndromes(ACS),are becoming a greater health issue.[1-3]Accordingly,the number of elderly patients in registries of myocardial infarction,is increasingly growing.[4,5]However,elderly patients are less likely to be treated with invasive strategy compared to younger patients,despite their intrinsic greater risk.[6,7]Several reports have described how quality initiatives improve treatment of ST elevation myocardial infarction(STEMI).
基金Project supported by the National High Technology Research and Development Program of China (Grant No.2007AA03Z403)the National Natural Science Foundation of China (Grant Nos.61076013 and 60776042)the National Basic Research Program of China (Grant No.2006CB921607)
文摘The influence of the width of a lattice-matched A10.82In0.18N/GaN single quantum well (SQW) on the absorption coefficients and wavelength of the intersubband transition (ISBT) has been investigated by solving the Schr5dinger and Poisson equations self-consistently. The wavelength of 1-2 ISBT increases with L, the thickness of the single quantum well, ranging from 2.88 ~m to 3.59 ~.m. The absorption coefficients of 1-2 ISBT increase with L at first and then decrease with L, with a maximum when L is equal to 2.6 nm. The wavelength of 1-3 ISBT decreases with L at first and then increases with L, with a minimum when L is equal to 4 nm, ranging from approximately 2.03 p^m to near 2.11 p.m. The absorption coefficients of 1-3 ISBT decrease with L. The results indicate that mid-infrared can be realized by the A10.s2In0.1sN/GaN SQW. In addition, the wavelength and absorption coefficients of ISBT can be adjusted by changing the width of the SQW.
基金supported by the Gudong Oil Production Plant of Shengli Oilfield Subsidiary Company,China Postdoctoral Science Foundation(Project 2013M530681)Hubei Province Natural Science Foundation(Project 2013CFB394)
文摘Traditional fluid production profile logging is not usually suitable for heavy-viscous crude oil wells.Biodegradation of heavy oil can lead to the loss of n-alkanes,and the use of chromatogram fingerprint techniques in studying the production contributions of single layers in heavy oil commingled wells has limitations.However,aromatic compounds are relatively well preserved.We took the heavy oil commingled wells of small layers NG55 and NG61 in the ninth area of the Gudong oil field as examples.Based on the principle of chromatography,the whole-oil GC-MS was used,and the aromatic parameters which have a strongly linear relationship with the ratio of mixed two end member oils were verified and selected in laboratory.Studies showed that the ratio of (1,4,6-+ 2,3,6-trimethylnaphthalene) to 1,2,5-trimethylnaphthalene has a strongly linear relationship with the ratio of the mixed two end member oils (R2=0.992).The oil contributions from single layers NG55 and NG61 in six commingled heavy oil wells were calculated using established charts and this relationship.The calculated results are consistent with the results of long period dynamic monitoring and logging interpretation in the study area and can provide a scientific basis for monitoring production performance and hierarchical management of reservoirs.The study provides a new geochemical method for calculation of the contributions of single layers in heavy oil commingled wells when conventional fluid production profile logging is not suitable.
基金funded by National Natural Science Foundation of China, grant numbers 62335006, 62274014, 62235016, 61734006, 61835011, 61991430funded by Key Program of the Chinese Academy of Sciences, grant numbers XDB43000000, QYZDJSSW-JSC027Beijing Municipal Science & Technology Commission, grant number Z221100002722018
文摘We demonstrated a scheme of phase-locked terahertz quantum cascade lasers(THz QCLs)array,with a single-mode pulse power of 108 mW at 13 K.The device utilizes a Talbot cavity to achieve phase locking among five ridge lasers with first-order buried distributed feedback(DFB)grating,resulting in nearly five times amplification of the single-mode power.Due to the optimum length of Talbot cavity depends on wavelength,the combination of Talbot cavity with the DFB grating leads to better power amplification than the combination with multimode Fabry-Perot(F-P)cavities.The Talbot cavity facet reflects light back to the ridge array direction and achieves self-imaging in the array,enabling phase-locked operation of ridges.We set the spacing between adjacent elements to be 220μm,much larger than the free-space wavelength,ensuring the operation of the fundamental supermode throughout the laser's dynamic range and obtaining a high-brightness far-field distribution.This scheme provides a new approach for enhancing the single-mode power of THz QCLs.
基金support from the European Space Agency(ESA)PRODEX(PROgramme de Développement d’Expériences scientifiques)Project mission(No.PEA4000134960)Partial funding was provided by the Romanian Ministry of Research,Innovation and Digitalization under Romanian National Core Program LAPLAS VII(Contract No.30N/2023)+2 种基金the Belgian Solar-Terrestrial Centre of Excellencesupported by the project Belgian Research Action through Interdisciplinary Networks(BRAIN-BE)2.0(Grant No.B2/223/P1/PLATINUM)funded by the Belgian Office for Research(BELSPO)partially supported by a grant from the Romanian Ministry of Education and Research(CNCS-UEFISCDI,Project No.PN-III-P1-1.1TE-2021-0102)。
文摘We derived the properties of the terrestrial magnetopause(MP)from two modeling approaches,one global–fluid,the other local–kinetic,and compared the results with data collected in situ by the Magnetospheric Multiscale 2(MMS2)spacecraft.We used global magnetohydrodynamic(MHD)simulations of the Earth’s magnetosphere(publicly available from the NASA-CCMC[National Aeronautics and Space Administration–Community Coordinated Modeling Center])and local Vlasov equilibrium models(based on kinetic models for tangential discontinuities)to extract spatial profiles of the plasma and field variables at the Earth’s MP.The global MHD simulations used initial solar wind conditions extracted from the OMNI database at the time epoch when the MMS2 observes the MP.The kinetic Vlasov model used asymptotic boundary conditions derived from the same in situ MMS measurements upstream or downstream of the MP.The global MHD simulations provide a three-dimensional image of the magnetosphere at the time when the MMS2 crosses the MP.The Vlasov model provides a one-dimensional local view of the MP derived from first principles of kinetic theory.The MMS2 experimental data also serve as a reference for comparing and validating the numerical simulations and modeling.We found that the MP transition layer formed in global MHD simulations was generally localized closer to the Earth(roughly by one Earth radius)from the position of the real MP observed by the MMS.We also found that the global MHD simulations overestimated the thickness of the MP transition by one order of magnitude for three analyzed variables:magnetic field,density,and tangential speed.The MP thickness derived from the local Vlasov equilibrium was consistent with observations for all three of these variables.The overestimation of density in the Vlasov equilibrium was reduced compared with the global MHD solutions.We discuss our results in the context of future SMILE(Solar wind Magnetosphere Ionosphere Link Explorer)campaigns for observing the Earth’s MP.