A new acrylic ester polymer YWB-7 resin was prepared and characterized. The properties of YWB-7 resin were compared with those of the commercial Amberlite XAD-7, Diaion HP2MG and hypercrosslinked macroporous polymer N...A new acrylic ester polymer YWB-7 resin was prepared and characterized. The properties of YWB-7 resin were compared with those of the commercial Amberlite XAD-7, Diaion HP2MG and hypercrosslinked macroporous polymer NDA-150 resins. Both surface area and micropore area of YWB-7 resin were bigger than those of XAD-7 resin and HP2MG resin. The YWB-7 resin was successfully employed to recycle 5-sodiosulfoisophthalic acids （SIPA） from its solutions with and without methanol.展开更多
Poly（vinylpyridine） WH-225 resin was prepared and characterized. Compared with the commercial hypercrosslinked adsorbent NDA-100 and macroporous adsorbent XAD-4 resins, the newly synthesized poly（vinylpyridine） WH...Poly（vinylpyridine） WH-225 resin was prepared and characterized. Compared with the commercial hypercrosslinked adsorbent NDA-100 and macroporous adsorbent XAD-4 resins, the newly synthesized poly（vinylpyridine） WH-225 resin exhibited the highest adsorption capacity toward SIPA from aqueous solution.展开更多
It has been demonstrated that single nucleotide polymorphisms(SNPs)of SIPA1(signal-induced proliferation associated gene 1)are associated with metastatic efficiency in both human and rodents.The purpose of this study ...It has been demonstrated that single nucleotide polymorphisms(SNPs)of SIPA1(signal-induced proliferation associated gene 1)are associated with metastatic efficiency in both human and rodents.The purpose of this study was to determine whether SIPA1545 C>T polymorphism was associated with overall survival in patients with metastatic breast cancer.In this study,SIPA1545 C>T polymorphism was detected in 185 metastatic breast cancer patients using polymerase chain reaction-restriction fragment length polymorphism assay(PCR-RFLP).Survival curves for patients with SIPA1545 C>T polymorphism was compared using the Kaplan-Meier method with log-rank tests.We found that SIPA1545 C>T polymorphism was significantly associated with survival in 185 patients with metastatic breast cancer.Patients with SIPA1545 T/T genotype had a significantly worse overall survival(OS)than did patients with C/T or C/C genotype(50.0%vs.62.9%,P=0.042).Moreover,in multivariate analysis,as compared with the C/C or C/T genotype,the T/T genotype remained an independent unfavorable prognostic marker of OS in this cohort(hazard ratio[HR]=2.16;95%CI=1.12–4.15;P=0.022).Our findings indicate that metastatic breast cancer patients with SIPA1545 T/T genotype have a poorer survival compared to patients with C/C or C/T genotype.展开更多
文摘A new acrylic ester polymer YWB-7 resin was prepared and characterized. The properties of YWB-7 resin were compared with those of the commercial Amberlite XAD-7, Diaion HP2MG and hypercrosslinked macroporous polymer NDA-150 resins. Both surface area and micropore area of YWB-7 resin were bigger than those of XAD-7 resin and HP2MG resin. The YWB-7 resin was successfully employed to recycle 5-sodiosulfoisophthalic acids （SIPA） from its solutions with and without methanol.
基金the National Natural Science Foundation of P.R.China(No.50578073)863 Project(2006AA06Z383)for financial support.
文摘Poly（vinylpyridine） WH-225 resin was prepared and characterized. Compared with the commercial hypercrosslinked adsorbent NDA-100 and macroporous adsorbent XAD-4 resins, the newly synthesized poly（vinylpyridine） WH-225 resin exhibited the highest adsorption capacity toward SIPA from aqueous solution.
基金This study was supported by the Program for Breast Cancer Tissue Bank of Beijing,and a grant from the National Natural Science Foundation of China(Grant No.30973436).
文摘It has been demonstrated that single nucleotide polymorphisms(SNPs)of SIPA1(signal-induced proliferation associated gene 1)are associated with metastatic efficiency in both human and rodents.The purpose of this study was to determine whether SIPA1545 C>T polymorphism was associated with overall survival in patients with metastatic breast cancer.In this study,SIPA1545 C>T polymorphism was detected in 185 metastatic breast cancer patients using polymerase chain reaction-restriction fragment length polymorphism assay(PCR-RFLP).Survival curves for patients with SIPA1545 C>T polymorphism was compared using the Kaplan-Meier method with log-rank tests.We found that SIPA1545 C>T polymorphism was significantly associated with survival in 185 patients with metastatic breast cancer.Patients with SIPA1545 T/T genotype had a significantly worse overall survival(OS)than did patients with C/T or C/C genotype(50.0%vs.62.9%,P=0.042).Moreover,in multivariate analysis,as compared with the C/C or C/T genotype,the T/T genotype remained an independent unfavorable prognostic marker of OS in this cohort(hazard ratio[HR]=2.16;95%CI=1.12–4.15;P=0.022).Our findings indicate that metastatic breast cancer patients with SIPA1545 T/T genotype have a poorer survival compared to patients with C/C or C/T genotype.
