Background:Prolonged sitting and reduced physical activity lead to low energy expenditures.However,little is known about the joint impact of daily sitting time and physical activity on body fat distribution.We investi...Background:Prolonged sitting and reduced physical activity lead to low energy expenditures.However,little is known about the joint impact of daily sitting time and physical activity on body fat distribution.We investigated the independent and joint associations of daily sitting time and physical activity with body fat among adults.Methods:This was a cross-sectional analysis of U.S.nationally representative data from the National Health and Nutrition Examination Survey2011-2018 among adults aged 20 years or older.Daily sitting time and leisure-time physical activity(LTPA)were self-reported using the Global Physical Activity Questionnaire.Body fat(total and trunk fat percentage)was determined via dual X-ray absorptiometry.Results:Among 10,808 adults,about 54.6%spent 6 h/day or more sitting;more than one-half reported no LTPA(inactive)or less than 150 min/week LTPA(insufficiently active)with only 43.3%reported 150 min/week or more LTPA(active)in the past week.After fully adjusting for sociodemographic data,lifestyle behaviors,and chronic conditions,prolonged sitting time and low levels of LTPA were associated with higher total and trunk fat percentages in both sexes.When stratifying by LTPA,the association between daily sitting time and body fat appeared to be stronger in those who were inactive/insuufficiently active.In the joint analyses,inactive/insuufficiently active adults who reported sitting more than 8 h/day had the highest total(female:3.99%(95%confidence interval(95%CI):3.09%-4.88%);male:3.79%(95%CI:2.75%-4.82%))and trunk body fat percentages(female:4.21%(95%CI:3.09%-5.32%);male:4.07%(95%CI:2.95%-5.19%))when compared with those who were active and sitting less than 4 h/day.Conclusion:Prolonged daily sitting time was associated with increased body fat among U.S.adults.The higher body fat associated with 6 h/day sitting may not be offset by achieving recommended levels of physical activity.展开更多
Do you spend many hours of the day siting?When you sit,you use less energy than you do when you are active.Siting toomuch hurts yourback,and it's bad for your heart it causes you to gain weight and may even increa...Do you spend many hours of the day siting?When you sit,you use less energy than you do when you are active.Siting toomuch hurts yourback,and it's bad for your heart it causes you to gain weight and may even increase your risk of cancer.How can you avoid siting too much?Every 30minutes,move and stretch.Better on thephone orwatch TV.展开更多
Purpose:This quasi-experimental study examined the impact of height-adjustable desks in combination with prompts to break up prolonged sitting time during class time and identified social and motivational factors asso...Purpose:This quasi-experimental study examined the impact of height-adjustable desks in combination with prompts to break up prolonged sitting time during class time and identified social and motivational factors associated with breaking up sitting time among adolescents.Teachers’perceptions of strategies were also examined.Methods:Over 17 weeks,1 classroom in a government secondary school in Melbourne,Australia,was equipped with 27 height-adjustable desks and prompts(posters and desk stickers)to break up classroom sitting time.Teachers received professional development in the use of the desks and prompts.One group of adolescents(n=55)had 2-5 lessons/week using the height-adjustable desks in an intervention classroom,and a comparison group matched by year level and subject(n=50)was taught in traditional“seated”classrooms.Adolescents wore an activPAL monitor at baseline(T0),4 weeks(T1),and 17 weeks(T2)and completed a survey at T0 and T2.Six teachers participated in interviews at T2.Effect sizes were calculated(d).Results:Linear mixed models found that,compared to the traditional“seated”classrooms,the adolescents in the intervention classroom had significantly lower sitting time(T1:-9.7 min/lesson,d=-0.96;T2:-6.7 min/lesson,d=-0.70)and time spent in sitting bouts>15 min(T2:-11.2 min/lesson,d=-0.62),and had significantly higher standing time(T1:7.3 min/lesson,d=0.84;T2:5.8 min/lesson,d=0.91),number of breaks from sitting(T1:1.3 breaks/lesson,d=0.49;T2:1.8 breaks/lesson,d=0.67),and stepping time(T1:2.5 min/lesson,d=0.66).Intervention classroom adolescents reported greater habit strength(d=0.58),self-efficacy for breaking up sitting time(d=0.75),and indicated that having a teacher/classmate remind them to stand as helpful(d=0.50).Conclusion:This intervention shows promise for targeting sitting behaviors in the classroom and indicates that incorporating social and motivational strategies may further enhance outcomes.展开更多
Objective: To observe the effect of lumbar spinal point injection on sitting function in children with cerebral palsy. Method: Sixty-two children with post-confirmed cerebral palsy were randomly divided into control g...Objective: To observe the effect of lumbar spinal point injection on sitting function in children with cerebral palsy. Method: Sixty-two children with post-confirmed cerebral palsy were randomly divided into control group and treatment group, 31 each. The control group was given conventional rehabilitation treatment, and the treatment group was given lumbar chiropspinal acupoint injection on the basis of the treatment method of the control group. After 3 consecutive courses of treatment, the sitting score of the two groups before and after treatment (GMFM88) was used to evaluate the sitting score before and after treatment. Outcome: Before treatment, the two groups were evaluated and the differences were not statistically significant (p > 0.05), which was comparable. The two groups (GMFM88) after treatment had significantly increased the differential values, and the difference was statistically significant compared with the same group before treatment (p Conclusion: Conventional rehabilitation combined with lumbar spinal point injection can effectively improve the sitting motor function of children with cerebral palsy.展开更多
Situs inversus totalis(SIT)is a rare homozygous recessive disease caused by the mutation in PKD1L1,which is required for normal interaction with PKD2 and leads to different complications such as respiratory disorders,...Situs inversus totalis(SIT)is a rare homozygous recessive disease caused by the mutation in PKD1L1,which is required for normal interaction with PKD2 and leads to different complications such as respiratory disorders,brain disorders and even obesity.The present study was designed to find out the mutational effect on the binding of PKD2 with mutated PKD1L1,which leads to SIT.The three-dimensional(3D)structure of wild type and mutated PKD1L1 was predicted with>90%confidence using different online tools.The different online tools that were employed were SWISS-MODEL,Phyre2(normal&intensive)and i-TASSER.To compute the physiochemical properties of PKD1L1(wild&mutated)and PKD2 in silico approaches were employed using the ExPASy ProtParam tool.Physicochemical properties such as molecular weight,isoelectric point,the total number of negatively and positively charged residues,extinction coefficient,half-life,instability and aliphatic index,grand average of hydropathicity,and amino acid percentage were calculated.A lot of variability was observed in these parameters among PKD1L1 and PKD2,which accounted for diversification in their functional properties.The theoretical pI points showed that PKD1L1(whole)is more basic with 6.64 pI compared to its first chain TOPO_DOM(amino acids from 1–1748)has a pI of 5.62 which means it is basic while PKD2 have the lowest pI point of 5.34.Docking was performed using the PatchDock and ClusPro online tools.展开更多
Most of the previous studies on the vibration ride comfort of the human-vehicle system were focused only on one or two aspects of the investigation. A hybrid approach which integrates all kinds of investigation method...Most of the previous studies on the vibration ride comfort of the human-vehicle system were focused only on one or two aspects of the investigation. A hybrid approach which integrates all kinds of investigation methods in real environment and virtual environment is described. The real experimental environment includes the WBV(whole body vibration) test, questionnaires for human subjective sensation and motion capture. The virtual experimental environment includes the theoretical calculation on simplified 5-DOF human body vibration model, the vibration simulation and analysis within ADAMS/VibrationTM module, and the digital human biomechanics and occupational health analysis in Jack software. While the real experimental environment provides realistic and accurate test results, it also serves as core and validation for the virtual experimental environment. The virtual experimental environment takes full advantages of current available vibration simulation and digital human modelling software, and makes it possible to evaluate the sitting posture comfort in a human-vehicle system with various human anthropometric parameters. How this digital evaluation system for car seat comfort design is fitted in the Industry 4.0 framework is also proposed.展开更多
The classification of sitting issues is investigated since detailed state classification for humanoid robots plays a key role in the practical application of humanoid robots, particularly for the humanoid robots doing...The classification of sitting issues is investigated since detailed state classification for humanoid robots plays a key role in the practical application of humanoid robots, particularly for the humanoid robots doing complicated tasks. This paper presents the concept, the characteristics tree, and the prototype of the humanoid robot SJTU-HR1. The basic states lbr humanoid robots are proposed, including lying, sitting, standing, and handstanding. Moreover, the sitting states are classified into several states from the viewpoint of topology. The Gy (generalized function) set theory is applied to achieve the kinematic characteristics of the interested end-effectors of the humanoid robot SJTU-HR1. Finally, the results indicate that a large number of the sitting states can be represented by the meaningful notations systematically. Furthermore, the one-to-one correspondence between the state and kinematic characteristics of the interested end-effectors of the SJTU-HR 1 leads to deeper insight into the capabilities of the humanoid robot SJTU-HR1.展开更多
Background: Prolonged sitting is a risk factor for low-back pain. The primary purpose of this study is to determine if prolonged active sitting will result in increased trunk motion. Methods: Fifteen healthy female ...Background: Prolonged sitting is a risk factor for low-back pain. The primary purpose of this study is to determine if prolonged active sitting will result in increased trunk motion. Methods: Fifteen healthy female participants volunteered to sit for 30 vain on each of three surfaces including an air-cushion, a stability ball, and a hard surface. Trunk motion was monitored using a Vicon motion capture system, and foot center of pressure was collected with two AMTI force plates. Results: Our findings indicated that the average speed of the trunk center of mass significantly increased with seating surface compliance. There were significant differences in fight and left foot centers of pressure in the antero-posterior direction between the ball and air-cushion conditions and the ball and chair conditions. Conclusion: Active sitting results in increased trunk motion and could have a positive effect on low-back health.展开更多
Background:As sedentary behavior is a global health issue,there is a need for methods of self-reported sitting assessment.The accuracy and reliability of these methods should also be tested in various populations and ...Background:As sedentary behavior is a global health issue,there is a need for methods of self-reported sitting assessment.The accuracy and reliability of these methods should also be tested in various populations and different cultural contexts.This study examined the validity of longterm and short-term recall of occupational sitting time in Finnish and Chinese subgroups.Methods:Two cohort groups of office-based workers(58.6%female,age range 2267 years)participated:a Finnish group(FIN,n=34)and a Chinese group(CHI,n=36).Long-term(past 3-month sitting)and short-term(daily sitting assessed on 5 consecutive days)single-item measures were used to assess self-reported occupational sitting time.Values from each participant were compared to objectively measured occupational sitting time assessed via thigh-mounted accelerometers,with Spearman’s rho(r)used to assess validity and the Bland-Altman method used to evaluate agreement.Coefficients of variation depicted day-to-day variability of time spent on sitting at work.Results:In the total study sample,the results showed that both long-term and short-term recall correlated with accelerometer-derived sitting time(r=0.532,95%confidence intervals(CI):0.3360.684,p<0.001;r=0.533,95%CI:0.4490.607,p<0.001,respectively).Compared to objectively measured sitting time,self-reported occupational sitting time was 2.4%(95%CI:0.5%to 5.3%,p=0.091)and 2.2%(95%CI:0.7%3.6%,p=0.005)greater for long-term and short-term recall,respectively.The agreement level was within the range21.2%to 25.9%for long-term recall,and24.2%to 28.5%for short-term recall.During a 5-day work week,day-to-day variation of sitting time was 9.4%§11.4%according to short-term recall and 10.4%§8.4%according to accelerometry-derived occupational sitting time.Conclusion:Overall,both long-term and short-term self-reported instruments provide acceptable measures of occupational sitting time in an office-based workplace,but their utility at the individual level is limited due to large variability.展开更多
Background:While the relationship between sedentary time and adiposity markers may be independent of moderate-to-vigorous intensity physical activity(MVPA) among adolescents,little is known about the role of light-int...Background:While the relationship between sedentary time and adiposity markers may be independent of moderate-to-vigorous intensity physical activity(MVPA) among adolescents,little is known about the role of light-intensity physical activity(LIPA) in this relationship.The aim of this cross-sectional study was to examine whether device-measured LIPA and MVPA moderate the associations between objectively measured sitting time and adiposity markers(body mass index(BMI)) and waist circumference(WC)) among adolescents.Methods:This study included accelerometer and inclinometer data obtained from 219 adolescents(age=14.9±1.6 years,mean± SD),collected during 2014 and 2015 in Melbourne,Australia.ActiGraph GT3 X accelerometers were used to determine time spent in total-LIPA(101 counts/min to 3.99 metabolic equivalents(METs)) was dichotomized into low-LIPA(101-799 counts/min) and high LIPA(800 counts/min to 3.99 METs),and MVPA(> 4 METs).The average time spent sitting was obtained from activPAL inclinometers.Anthropometric measures were assessed by trained staff.Interactions between sitting and total-LIPA,low-LIPA,high-LIPA,and MVPA on BMI z-score(zBMI) and WC z-score(zWC),respectively,were examined using linear regression,adjusting for age and sex;and moderation by total-LIPA,low-LIPA,high-LIPA,and MVPA were examined by adding interaction terms.Significant interaction effects were probed by comparing associations at the mean and at 1 SD below and above the mean.Results:Total-LIPA significantly moderated the association between sitting time and zBMI,and low-LIPA significantly moderated the association between sitting time and zBMI and zWC.No other associations were found for total-LIPA,high-LIPA,or MVPA.Specifically,at high levels of total-LIPA(+1 SD),there is a negative association between sitting time and zBMI.In addition,at high levels of low-LIPA(+1 SD),there is a negative association between sitting time and zBMI and zWC.Conclusion:Associations between sitting and adiposity depended on time spent in total-LIPA and low-LIPA,but not high-LIPA or MVPA.Results suggest that increasing time spent in LIP A may provide protection from the deleterious effects of sitting on adiposity markers among adolescents.Experimental evidence is needed to support these conclusions.展开更多
In this paper,the author introduced her clinical observation and main points ofoperation on sitting still of Qigong plus blood pricking therapy founded by herself for treatment of 21cases of Aids.Results showed that t...In this paper,the author introduced her clinical observation and main points ofoperation on sitting still of Qigong plus blood pricking therapy founded by herself for treatment of 21cases of Aids.Results showed that this therapy had actions in clearing away heat and toxic materials,strengthenign the body resistance to eliminate pathogenic factors and enhancing the immune functionand the ability against diseases of the human body which played important roles in controlling syrup-toms of patients with Aids and prolonging their life span.展开更多
Cerebral disorders are often associated with disturbance of consciousness. Since the latter could alter the prognosis of physical function, early improvement of consciousness level is important. The present study test...Cerebral disorders are often associated with disturbance of consciousness. Since the latter could alter the prognosis of physical function, early improvement of consciousness level is important. The present study tested the hypothesis that sitting position improves disturbances of consciousness in patients with cerebral disorders. The subjects were 17 patients with cerebral disorders and disturbances of consciousness. The consciousness level was evaluated in supine position and following a change to sitting position. The consciousness level was evaluated by the Glasgow Coma Scale (GCS). The total, eye opening, and motor GCS scores were significantly higher in the sitting position compared with the supine position. In conclusions, changing from supine to sitting position improves consciousness level in patients with cerebral disorders.展开更多
Context: Atrial septal defect may rarely be associated with other cardiac diseases such as arrhythmia, and may require additional intervention. Case report: A 16-year-old boy presented with effort dyspnea, tiredness, ...Context: Atrial septal defect may rarely be associated with other cardiac diseases such as arrhythmia, and may require additional intervention. Case report: A 16-year-old boy presented with effort dyspnea, tiredness, and fatigue. The electrocardiograph revealed right bundle branch block, atrioventricular block, and left axis deviation. Ostium secundum type of atrial septal defect was detected by transthoracic echocardiography and was confirmed by transesophageal echocardiography. The patient was advised to undergo percutaneous device closure. Permanent pacemaker implantation was also suggested considering the risk of fatal arrhythmias associated with atrioventricular block. Consequently, patient underwent percutaneous atrial septal defect closure and implantation of pacemaker in a single sitting. Both the procedures were successful, after which the patient showed remarkable symptomatic improvement. Conclusion: In atrial septal defect patients with unexplained atrioventricular block, closure of atrial septal defect and implantation of pacemaker in single sitting appear to be an attractive modality.展开更多
Purpose:This study aimed to evaluate the effectiveness of physical activity(PA)interrupting prolonged sitting(PS)on postprandial glycemia and insulin responses among adults.Methods:PubMed,EMBASE,Cochrane Library,Web o...Purpose:This study aimed to evaluate the effectiveness of physical activity(PA)interrupting prolonged sitting(PS)on postprandial glycemia and insulin responses among adults.Methods:PubMed,EMBASE,Cochrane Library,Web of Science,CINAHL,PsycINFO,and the China National Knowledge Infrastructure databases were searched through September 30,2020.Randomized controlled trials(RCTs)that examined the effect of all forms of PA interrupting PS on postprandial glycemia and/or insulin responses among adults without chronic diseases were included in this study.The risk of bias of included studies was evaluated based on the Cochrane tool.A network meta-analysis was performed to estimate the summary standardized mean differences(SMDs)with 95%confidence intervals(95%CIs)with random effects.Results:Thirty crossover RCTs were included in our review.These RCTs included 9 types of interventions that interrupted PS.When compared to PS by itself,light-intensity PA intermittent interrupting(LPA-INT)PS and moderate-intensity PA intermittent interrupting(MPA-INT)PS significantly lowered postprandial glycemia(SMD=-0.46,95%CI:-0.70 to-0.21;SMD=-0.69,95%CI:-1.00 to-0.37,respectively)and significantly reduced postprandial insulin response(SMD=-0.46,95%CI:-0.66 to-0.26;SMD=-0.47,95%CI:-0.77 to-0.17,respectively).Results of the clustered ranking plot indicated that MPA-INT was the most effective intervention in lowering postprandial glycemia and insulin responses.Conclusion:Replacing PS with MPA-INT or LPA-INT has a positive effect in reducing postprandial glycemia and insulin responses,with MPA-INT being the optimal intervention strategy.展开更多
The purpose of this cross-sectional study was to investigate the reliability and validity of two sitting balance tests, namely limits of stability test (LOS) and sequential weight shifting test (SWS) in stroke survivo...The purpose of this cross-sectional study was to investigate the reliability and validity of two sitting balance tests, namely limits of stability test (LOS) and sequential weight shifting test (SWS) in stroke survivors. Eleven community-dwelling stroke survivors with onset for at least two years (mean time since stroke = 8.0 years (SD 4.0)) and fifteen healthy subjects were recruited. Reaction time, maximum excursion, directional control of LOS, and total movement time and directional control of SWS were measured. Modified Function Reach Test (MFRT) and Trunk Impairment Scale (TIS) were also conducted to correlate with LOS and SWS. Result demonstrated excellent test-retest reliability in reaction time (ICC [3,8] = 0.760) and maximum excursion (ICC [3,8] = 0.929) of LOS and total movement time of SWS (ICC [3,3] = 0.864) in stroke survivors. Known groups validity was only shown in reaction time of LOS (p = 0.039) between the two groups. Reaction time of LOS of stroke subjects was significantly correlated with MFRT (r = −0.684, p = 0.020), while directional control of LOS was significantly correlated with the dynamic sitting balance score (r = 0.846, p = 0.001) and total score (r = 0.817, p = 0.002) of TIS. For SWS, total movement time was significantly correlated with dynamic sitting balance score of TIS (r = −0.654, p = 0.029). In conclusion, moderate to excellent test-retest reliability was found in LOS and SWS tests in stroke survivors. The convergence and discrimination perspectives of construct validity were established. Further study with a larger sample size and in a frailer stroke population is warranted.展开更多
Pressure ulcers are a common complication among wheelchair-bound population. They are resulted from prolonged exposure to high pressure, which restricts blood flow and leads to tissue necrosis. In this work, a continu...Pressure ulcers are a common complication among wheelchair-bound population. They are resulted from prolonged exposure to high pressure, which restricts blood flow and leads to tissue necrosis. In this work, a continuous pressure monitoring system is developed for pressure ulcer prevention. The system consists of 64 pressure sensors on a 40×50 cm2 sheet. Real time pressure data and corresponding maps are displayed on a computer simultaneously. Furthermore, a posture detection procedure is proposed for sitting posture identification. Having information about the patient’s postural history, caregivers are capable of a better decision about repositioning and treating the patient.展开更多
Flexible pressure monitoring device can help correct the sitting posture and prevent health problems(e.g.,deformity of spinal column and musculoskeletal disease).Currently,most measurement systems hinder their wide ap...Flexible pressure monitoring device can help correct the sitting posture and prevent health problems(e.g.,deformity of spinal column and musculoskeletal disease).Currently,most measurement systems hinder their wide applications owing to the high cost or low accuracy.In this study,a flexible sitting pressure measurement system was proposed based on a textile-based capacitive pressure sensor array in order to measure sitting pressure distribution simply and conveniently.The capacitive pressure sensor array is sandwich structure composed of a high-density sponge layer and two electrode array fabrics,which possesses high resolution(2.26 sensors/cm2),high sensitivity(0.701 kPa-1)and fast response(≤35 ms).It is worth noting that the raw materials of the sensing fabric include commercialized copper sheets and polyester yarns.The as-prepared pressure measurement system can accurately measure the pressure distribution nephogram for sitting posture analysis.The sitting pressure of 10 volunteers was measured and six types of posture were distinguished clearly.展开更多
文摘Background:Prolonged sitting and reduced physical activity lead to low energy expenditures.However,little is known about the joint impact of daily sitting time and physical activity on body fat distribution.We investigated the independent and joint associations of daily sitting time and physical activity with body fat among adults.Methods:This was a cross-sectional analysis of U.S.nationally representative data from the National Health and Nutrition Examination Survey2011-2018 among adults aged 20 years or older.Daily sitting time and leisure-time physical activity(LTPA)were self-reported using the Global Physical Activity Questionnaire.Body fat(total and trunk fat percentage)was determined via dual X-ray absorptiometry.Results:Among 10,808 adults,about 54.6%spent 6 h/day or more sitting;more than one-half reported no LTPA(inactive)or less than 150 min/week LTPA(insufficiently active)with only 43.3%reported 150 min/week or more LTPA(active)in the past week.After fully adjusting for sociodemographic data,lifestyle behaviors,and chronic conditions,prolonged sitting time and low levels of LTPA were associated with higher total and trunk fat percentages in both sexes.When stratifying by LTPA,the association between daily sitting time and body fat appeared to be stronger in those who were inactive/insuufficiently active.In the joint analyses,inactive/insuufficiently active adults who reported sitting more than 8 h/day had the highest total(female:3.99%(95%confidence interval(95%CI):3.09%-4.88%);male:3.79%(95%CI:2.75%-4.82%))and trunk body fat percentages(female:4.21%(95%CI:3.09%-5.32%);male:4.07%(95%CI:2.95%-5.19%))when compared with those who were active and sitting less than 4 h/day.Conclusion:Prolonged daily sitting time was associated with increased body fat among U.S.adults.The higher body fat associated with 6 h/day sitting may not be offset by achieving recommended levels of physical activity.
文摘Do you spend many hours of the day siting?When you sit,you use less energy than you do when you are active.Siting toomuch hurts yourback,and it's bad for your heart it causes you to gain weight and may even increase your risk of cancer.How can you avoid siting too much?Every 30minutes,move and stretch.Better on thephone orwatch TV.
基金This study has received a seed funding from Deakin University’s School of Exercise and Nutrition Sciences(2015)BS was supported by funding from a National Health and Medical Research Council(NHMRC)Centre of Research Excellence(APP1057608)+2 种基金AMCA was supported by a Deakin University Postgraduate Research Scholarship(DUPRS).AT was supported by a National Heart Foundation of Australia Future Leader Fellowship award(Award ID 100046)during this studyDWD is supported by an NHMRC Senior Research Fellowship(APP1078360)and by the Victorian Government’s Operational Infrastructure Support ProgramLA is supported by an Alfred Deakin Postdoctoral Research Fellowship.JS was supported by an NHMRC Principal Research Fellowship(APP1026216)during this research.The authors are grateful to the principal,teachers,and adolescents for their participation in this study。
文摘Purpose:This quasi-experimental study examined the impact of height-adjustable desks in combination with prompts to break up prolonged sitting time during class time and identified social and motivational factors associated with breaking up sitting time among adolescents.Teachers’perceptions of strategies were also examined.Methods:Over 17 weeks,1 classroom in a government secondary school in Melbourne,Australia,was equipped with 27 height-adjustable desks and prompts(posters and desk stickers)to break up classroom sitting time.Teachers received professional development in the use of the desks and prompts.One group of adolescents(n=55)had 2-5 lessons/week using the height-adjustable desks in an intervention classroom,and a comparison group matched by year level and subject(n=50)was taught in traditional“seated”classrooms.Adolescents wore an activPAL monitor at baseline(T0),4 weeks(T1),and 17 weeks(T2)and completed a survey at T0 and T2.Six teachers participated in interviews at T2.Effect sizes were calculated(d).Results:Linear mixed models found that,compared to the traditional“seated”classrooms,the adolescents in the intervention classroom had significantly lower sitting time(T1:-9.7 min/lesson,d=-0.96;T2:-6.7 min/lesson,d=-0.70)and time spent in sitting bouts>15 min(T2:-11.2 min/lesson,d=-0.62),and had significantly higher standing time(T1:7.3 min/lesson,d=0.84;T2:5.8 min/lesson,d=0.91),number of breaks from sitting(T1:1.3 breaks/lesson,d=0.49;T2:1.8 breaks/lesson,d=0.67),and stepping time(T1:2.5 min/lesson,d=0.66).Intervention classroom adolescents reported greater habit strength(d=0.58),self-efficacy for breaking up sitting time(d=0.75),and indicated that having a teacher/classmate remind them to stand as helpful(d=0.50).Conclusion:This intervention shows promise for targeting sitting behaviors in the classroom and indicates that incorporating social and motivational strategies may further enhance outcomes.
文摘Objective: To observe the effect of lumbar spinal point injection on sitting function in children with cerebral palsy. Method: Sixty-two children with post-confirmed cerebral palsy were randomly divided into control group and treatment group, 31 each. The control group was given conventional rehabilitation treatment, and the treatment group was given lumbar chiropspinal acupoint injection on the basis of the treatment method of the control group. After 3 consecutive courses of treatment, the sitting score of the two groups before and after treatment (GMFM88) was used to evaluate the sitting score before and after treatment. Outcome: Before treatment, the two groups were evaluated and the differences were not statistically significant (p > 0.05), which was comparable. The two groups (GMFM88) after treatment had significantly increased the differential values, and the difference was statistically significant compared with the same group before treatment (p Conclusion: Conventional rehabilitation combined with lumbar spinal point injection can effectively improve the sitting motor function of children with cerebral palsy.
文摘Situs inversus totalis(SIT)is a rare homozygous recessive disease caused by the mutation in PKD1L1,which is required for normal interaction with PKD2 and leads to different complications such as respiratory disorders,brain disorders and even obesity.The present study was designed to find out the mutational effect on the binding of PKD2 with mutated PKD1L1,which leads to SIT.The three-dimensional(3D)structure of wild type and mutated PKD1L1 was predicted with>90%confidence using different online tools.The different online tools that were employed were SWISS-MODEL,Phyre2(normal&intensive)and i-TASSER.To compute the physiochemical properties of PKD1L1(wild&mutated)and PKD2 in silico approaches were employed using the ExPASy ProtParam tool.Physicochemical properties such as molecular weight,isoelectric point,the total number of negatively and positively charged residues,extinction coefficient,half-life,instability and aliphatic index,grand average of hydropathicity,and amino acid percentage were calculated.A lot of variability was observed in these parameters among PKD1L1 and PKD2,which accounted for diversification in their functional properties.The theoretical pI points showed that PKD1L1(whole)is more basic with 6.64 pI compared to its first chain TOPO_DOM(amino acids from 1–1748)has a pI of 5.62 which means it is basic while PKD2 have the lowest pI point of 5.34.Docking was performed using the PatchDock and ClusPro online tools.
基金Supported by National Natural Science Foundation of China(Grant No.51465056)Xinjiang Provincial Natural Science Foundation of China(Grant No.2015211C265)Xinjiang University Ph D Start-up Funds,China
文摘Most of the previous studies on the vibration ride comfort of the human-vehicle system were focused only on one or two aspects of the investigation. A hybrid approach which integrates all kinds of investigation methods in real environment and virtual environment is described. The real experimental environment includes the WBV(whole body vibration) test, questionnaires for human subjective sensation and motion capture. The virtual experimental environment includes the theoretical calculation on simplified 5-DOF human body vibration model, the vibration simulation and analysis within ADAMS/VibrationTM module, and the digital human biomechanics and occupational health analysis in Jack software. While the real experimental environment provides realistic and accurate test results, it also serves as core and validation for the virtual experimental environment. The virtual experimental environment takes full advantages of current available vibration simulation and digital human modelling software, and makes it possible to evaluate the sitting posture comfort in a human-vehicle system with various human anthropometric parameters. How this digital evaluation system for car seat comfort design is fitted in the Industry 4.0 framework is also proposed.
基金Acknowledgement This work was supported by the National Basic Research Program of China (2006CB705402), the Na- tional Natural Science Foundation of China (30770538, 50821003), and the Joint Research Fund for Overseas Natural Science of China.
文摘The classification of sitting issues is investigated since detailed state classification for humanoid robots plays a key role in the practical application of humanoid robots, particularly for the humanoid robots doing complicated tasks. This paper presents the concept, the characteristics tree, and the prototype of the humanoid robot SJTU-HR1. The basic states lbr humanoid robots are proposed, including lying, sitting, standing, and handstanding. Moreover, the sitting states are classified into several states from the viewpoint of topology. The Gy (generalized function) set theory is applied to achieve the kinematic characteristics of the interested end-effectors of the humanoid robot SJTU-HR1. Finally, the results indicate that a large number of the sitting states can be represented by the meaningful notations systematically. Furthermore, the one-to-one correspondence between the state and kinematic characteristics of the interested end-effectors of the SJTU-HR 1 leads to deeper insight into the capabilities of the humanoid robot SJTU-HR1.
文摘Background: Prolonged sitting is a risk factor for low-back pain. The primary purpose of this study is to determine if prolonged active sitting will result in increased trunk motion. Methods: Fifteen healthy female participants volunteered to sit for 30 vain on each of three surfaces including an air-cushion, a stability ball, and a hard surface. Trunk motion was monitored using a Vicon motion capture system, and foot center of pressure was collected with two AMTI force plates. Results: Our findings indicated that the average speed of the trunk center of mass significantly increased with seating surface compliance. There were significant differences in fight and left foot centers of pressure in the antero-posterior direction between the ball and air-cushion conditions and the ball and chair conditions. Conclusion: Active sitting results in increased trunk motion and could have a positive effect on low-back health.
基金supported by the China Scholarship Council(No.201206320092),China.
文摘Background:As sedentary behavior is a global health issue,there is a need for methods of self-reported sitting assessment.The accuracy and reliability of these methods should also be tested in various populations and different cultural contexts.This study examined the validity of longterm and short-term recall of occupational sitting time in Finnish and Chinese subgroups.Methods:Two cohort groups of office-based workers(58.6%female,age range 2267 years)participated:a Finnish group(FIN,n=34)and a Chinese group(CHI,n=36).Long-term(past 3-month sitting)and short-term(daily sitting assessed on 5 consecutive days)single-item measures were used to assess self-reported occupational sitting time.Values from each participant were compared to objectively measured occupational sitting time assessed via thigh-mounted accelerometers,with Spearman’s rho(r)used to assess validity and the Bland-Altman method used to evaluate agreement.Coefficients of variation depicted day-to-day variability of time spent on sitting at work.Results:In the total study sample,the results showed that both long-term and short-term recall correlated with accelerometer-derived sitting time(r=0.532,95%confidence intervals(CI):0.3360.684,p<0.001;r=0.533,95%CI:0.4490.607,p<0.001,respectively).Compared to objectively measured sitting time,self-reported occupational sitting time was 2.4%(95%CI:0.5%to 5.3%,p=0.091)and 2.2%(95%CI:0.7%3.6%,p=0.005)greater for long-term and short-term recall,respectively.The agreement level was within the range21.2%to 25.9%for long-term recall,and24.2%to 28.5%for short-term recall.During a 5-day work week,day-to-day variation of sitting time was 9.4%§11.4%according to short-term recall and 10.4%§8.4%according to accelerometry-derived occupational sitting time.Conclusion:Overall,both long-term and short-term self-reported instruments provide acceptable measures of occupational sitting time in an office-based workplace,but their utility at the individual level is limited due to large variability.
基金funded by the National Institutes for Health (NIH) (R01 HL 111378)AMCA is supported by a Deakin University Postgraduate Research Scholarship (DUPRS)+5 种基金JS was supported by a NHMRC Principal Research Fellowship (APP1026216) during this researchDWD is supported by an NHMRC Senior Research Fellowship (APP1078360)the Victorian Government’s Operational Infrastructure Support ProgramLA is supported by an Alfred Deakin Postdoctoral Research Fellowshipsupported by a National Heart Foundation of Australia Future Leader Fellowship (Award ID 100046) during this researchJS,DWD,and AT received funding support from an NHMRC Centre for Research Excellence Grant (APP1057608)。
文摘Background:While the relationship between sedentary time and adiposity markers may be independent of moderate-to-vigorous intensity physical activity(MVPA) among adolescents,little is known about the role of light-intensity physical activity(LIPA) in this relationship.The aim of this cross-sectional study was to examine whether device-measured LIPA and MVPA moderate the associations between objectively measured sitting time and adiposity markers(body mass index(BMI)) and waist circumference(WC)) among adolescents.Methods:This study included accelerometer and inclinometer data obtained from 219 adolescents(age=14.9±1.6 years,mean± SD),collected during 2014 and 2015 in Melbourne,Australia.ActiGraph GT3 X accelerometers were used to determine time spent in total-LIPA(101 counts/min to 3.99 metabolic equivalents(METs)) was dichotomized into low-LIPA(101-799 counts/min) and high LIPA(800 counts/min to 3.99 METs),and MVPA(> 4 METs).The average time spent sitting was obtained from activPAL inclinometers.Anthropometric measures were assessed by trained staff.Interactions between sitting and total-LIPA,low-LIPA,high-LIPA,and MVPA on BMI z-score(zBMI) and WC z-score(zWC),respectively,were examined using linear regression,adjusting for age and sex;and moderation by total-LIPA,low-LIPA,high-LIPA,and MVPA were examined by adding interaction terms.Significant interaction effects were probed by comparing associations at the mean and at 1 SD below and above the mean.Results:Total-LIPA significantly moderated the association between sitting time and zBMI,and low-LIPA significantly moderated the association between sitting time and zBMI and zWC.No other associations were found for total-LIPA,high-LIPA,or MVPA.Specifically,at high levels of total-LIPA(+1 SD),there is a negative association between sitting time and zBMI.In addition,at high levels of low-LIPA(+1 SD),there is a negative association between sitting time and zBMI and zWC.Conclusion:Associations between sitting and adiposity depended on time spent in total-LIPA and low-LIPA,but not high-LIPA or MVPA.Results suggest that increasing time spent in LIP A may provide protection from the deleterious effects of sitting on adiposity markers among adolescents.Experimental evidence is needed to support these conclusions.
文摘In this paper,the author introduced her clinical observation and main points ofoperation on sitting still of Qigong plus blood pricking therapy founded by herself for treatment of 21cases of Aids.Results showed that this therapy had actions in clearing away heat and toxic materials,strengthenign the body resistance to eliminate pathogenic factors and enhancing the immune functionand the ability against diseases of the human body which played important roles in controlling syrup-toms of patients with Aids and prolonging their life span.
文摘Cerebral disorders are often associated with disturbance of consciousness. Since the latter could alter the prognosis of physical function, early improvement of consciousness level is important. The present study tested the hypothesis that sitting position improves disturbances of consciousness in patients with cerebral disorders. The subjects were 17 patients with cerebral disorders and disturbances of consciousness. The consciousness level was evaluated in supine position and following a change to sitting position. The consciousness level was evaluated by the Glasgow Coma Scale (GCS). The total, eye opening, and motor GCS scores were significantly higher in the sitting position compared with the supine position. In conclusions, changing from supine to sitting position improves consciousness level in patients with cerebral disorders.
文摘Context: Atrial septal defect may rarely be associated with other cardiac diseases such as arrhythmia, and may require additional intervention. Case report: A 16-year-old boy presented with effort dyspnea, tiredness, and fatigue. The electrocardiograph revealed right bundle branch block, atrioventricular block, and left axis deviation. Ostium secundum type of atrial septal defect was detected by transthoracic echocardiography and was confirmed by transesophageal echocardiography. The patient was advised to undergo percutaneous device closure. Permanent pacemaker implantation was also suggested considering the risk of fatal arrhythmias associated with atrioventricular block. Consequently, patient underwent percutaneous atrial septal defect closure and implantation of pacemaker in a single sitting. Both the procedures were successful, after which the patient showed remarkable symptomatic improvement. Conclusion: In atrial septal defect patients with unexplained atrioventricular block, closure of atrial septal defect and implantation of pacemaker in single sitting appear to be an attractive modality.
基金supported by grants to MQ from the National Key Research and Development Program of China (2020YFC2003301 and 2020YFC2007005)National Natural Science Foundation of China (81703252)+1 种基金Shanghai Committee of Science and Technology of China(19080503000)HW from the Public Welfare Technology Project of the Zhejiang Science Department(LGF18H170006)
文摘Purpose:This study aimed to evaluate the effectiveness of physical activity(PA)interrupting prolonged sitting(PS)on postprandial glycemia and insulin responses among adults.Methods:PubMed,EMBASE,Cochrane Library,Web of Science,CINAHL,PsycINFO,and the China National Knowledge Infrastructure databases were searched through September 30,2020.Randomized controlled trials(RCTs)that examined the effect of all forms of PA interrupting PS on postprandial glycemia and/or insulin responses among adults without chronic diseases were included in this study.The risk of bias of included studies was evaluated based on the Cochrane tool.A network meta-analysis was performed to estimate the summary standardized mean differences(SMDs)with 95%confidence intervals(95%CIs)with random effects.Results:Thirty crossover RCTs were included in our review.These RCTs included 9 types of interventions that interrupted PS.When compared to PS by itself,light-intensity PA intermittent interrupting(LPA-INT)PS and moderate-intensity PA intermittent interrupting(MPA-INT)PS significantly lowered postprandial glycemia(SMD=-0.46,95%CI:-0.70 to-0.21;SMD=-0.69,95%CI:-1.00 to-0.37,respectively)and significantly reduced postprandial insulin response(SMD=-0.46,95%CI:-0.66 to-0.26;SMD=-0.47,95%CI:-0.77 to-0.17,respectively).Results of the clustered ranking plot indicated that MPA-INT was the most effective intervention in lowering postprandial glycemia and insulin responses.Conclusion:Replacing PS with MPA-INT or LPA-INT has a positive effect in reducing postprandial glycemia and insulin responses,with MPA-INT being the optimal intervention strategy.
文摘The purpose of this cross-sectional study was to investigate the reliability and validity of two sitting balance tests, namely limits of stability test (LOS) and sequential weight shifting test (SWS) in stroke survivors. Eleven community-dwelling stroke survivors with onset for at least two years (mean time since stroke = 8.0 years (SD 4.0)) and fifteen healthy subjects were recruited. Reaction time, maximum excursion, directional control of LOS, and total movement time and directional control of SWS were measured. Modified Function Reach Test (MFRT) and Trunk Impairment Scale (TIS) were also conducted to correlate with LOS and SWS. Result demonstrated excellent test-retest reliability in reaction time (ICC [3,8] = 0.760) and maximum excursion (ICC [3,8] = 0.929) of LOS and total movement time of SWS (ICC [3,3] = 0.864) in stroke survivors. Known groups validity was only shown in reaction time of LOS (p = 0.039) between the two groups. Reaction time of LOS of stroke subjects was significantly correlated with MFRT (r = −0.684, p = 0.020), while directional control of LOS was significantly correlated with the dynamic sitting balance score (r = 0.846, p = 0.001) and total score (r = 0.817, p = 0.002) of TIS. For SWS, total movement time was significantly correlated with dynamic sitting balance score of TIS (r = −0.654, p = 0.029). In conclusion, moderate to excellent test-retest reliability was found in LOS and SWS tests in stroke survivors. The convergence and discrimination perspectives of construct validity were established. Further study with a larger sample size and in a frailer stroke population is warranted.
文摘Pressure ulcers are a common complication among wheelchair-bound population. They are resulted from prolonged exposure to high pressure, which restricts blood flow and leads to tissue necrosis. In this work, a continuous pressure monitoring system is developed for pressure ulcer prevention. The system consists of 64 pressure sensors on a 40×50 cm2 sheet. Real time pressure data and corresponding maps are displayed on a computer simultaneously. Furthermore, a posture detection procedure is proposed for sitting posture identification. Having information about the patient’s postural history, caregivers are capable of a better decision about repositioning and treating the patient.
基金Fundamental Research Fund for the Central Universities,China(Nos.2232020G-01 and 19D110106)Young Elite Scientists Sponsorship Program by China Association for Science and Technology,China(No.2017QNRC001)Graduate Student Innovation Fund of Donghua University,China(No.20D310111)。
文摘Flexible pressure monitoring device can help correct the sitting posture and prevent health problems(e.g.,deformity of spinal column and musculoskeletal disease).Currently,most measurement systems hinder their wide applications owing to the high cost or low accuracy.In this study,a flexible sitting pressure measurement system was proposed based on a textile-based capacitive pressure sensor array in order to measure sitting pressure distribution simply and conveniently.The capacitive pressure sensor array is sandwich structure composed of a high-density sponge layer and two electrode array fabrics,which possesses high resolution(2.26 sensors/cm2),high sensitivity(0.701 kPa-1)and fast response(≤35 ms).It is worth noting that the raw materials of the sensing fabric include commercialized copper sheets and polyester yarns.The as-prepared pressure measurement system can accurately measure the pressure distribution nephogram for sitting posture analysis.The sitting pressure of 10 volunteers was measured and six types of posture were distinguished clearly.