Effect of Cognitive Behavioral Intervention on Plasma Cortisol in Patients with Breast Cancer PTSD

Objective: To investigate the effect of cognitive behavioral intervention on plasma cortisol in patients with breast cancer PTSD before surgery. Methods: SCL-90, EPQ-N and cognitive behavior intervention were performed on 30 patients with PTSD, 30 patients without PTSD and 30 normal subjects, and their fasting blood was collected to analyze cortisol in the morning. Results: The scores of SCL-90 and EPQ-N in patients with breast cancer PTSD were significantly higher than those in non-PTSD patients and normal subjects (P < 0.01). After cognitive behavioral intervention, the plasma cortisol level of breast cancer PTSD patients was significantly decreased (P Conclusion: Compared with non-PTSD breast cancer patients and normal control group, breast cancer PTSD patients had more serious psychological problems, worse emotional stability and higher plasma cortisol level. Cognitive-behavioral intervention can effectively reduce plasma cortisol levels in breast cancer patients with PTSD.

Effects of comprehensive nursing with cognitive behavioral therapy in orthodontic osteodilated arch treatment

BACKGROUND This work explored the effects of cognitive behavior therapy(CBT)-based comprehensive nursing intervention(CNI)mode in arch expansion to treat patients with orthodontic osteodilated arch(OOA).AIM To explore the application effect of CBT-based CNI model in orthodontic expansion arch treatment.METHODS Using convenient sampling method,81 patients with OOA were selected and rolled into a control group(Ctrl group,40 cases)and an observation group(Obs group,41 cases).During the treatment,patients in the Ctrl group received routine nursing intervention mode,and the those in the Obs group received CBT mode on the basis of this.Before and after intervention,the incidence of oral mucositis,the mastery rate of correct arch expansion method,self-rating anxiety scale score,soft scale index,and plaque index were compared for patients in different groups.In addition,satisfaction and complications were comparatively analyzed.RESULTS Incidence of oral mucositis in the Obs group was lower(14.6%vs 38.5%),and the mastery rate of correct arch expansion method was obviously higher(90.2%vs 55.0%)was obviously higher(all P<0.05).Meanwhile,the soft scale index and plaque index in the Obs group were much lower(P<0.05).The compliance(90.24%)and satisfaction(95.12%)in the Obs group were greatly higher(P<0.05).CONCLUSION The CBT-based CNI mode greatly improved the mastery rate of correct arch expansion method during arch expansion in treating patients with OOA and enhanced the therapeutic effect of arch expansion and the oral health of patients,improving the patient compliance.

Effect of cognitive behavioral group therapy on rehabilitation of community patients with schizophrenia:A short-term randomized control trial

BACKGROUND The efficacy of cognitive behavioral group therapy(CBGT)for cognitive dysfunction and negative symptoms of schizophrenia is established,but more evidence is required.AIM To assess the effectiveness of CBGT combined with mental health education as a treatment for schizophrenia compared with mental health education alone.METHODS In all,120 schizophrenia out-patients were randomized into CBGT combined with mental health education or single mental health education.The primary outcomes were positive and negative symptoms,cognitive function,excitatory factor,anxiety and depression symptom improvements on the positive and negative syndrome scale score.Secondary outcome measures included social function and drug compliance.RESULTS There were significant differences between CBGT combined with mental health education and single mental health education on measures of positive and negative symptoms,cognitive functions,excitatory factor,anxiety and depression symptoms,and social functions.No other significant difference in outcomes was observed.CONCLUSION CBGT combined with mental health education may be relevant beneficial treatment method in reducing symptoms,cognitive and social functions of patients with schizophrenia.

Effect of Montessori method on the cognitive and behavioral intervention of senile dementia patients:a meta-analysis

Background:To evaluate the effect of Montessori method on cognitive and behavioral function in patients with senile dementia by meta-analysis.Methods:The randomized controlled trials of the effect of Montessori method on cognitive and behavioral functions of Alzheimer’s patients in PubMed,Cochrane Library,Web of Science,Excerpt Medica Database,The Cumulative Index to Nursing&Allied Health Literature,Chinese BioMedical Literature Database,China National Knowledge Infrastructure,Weipu Information Chinese Periodical Service Platformdatabase and Wanfang database were searched by computer,and the references of relevant literatures were traced.Two researchers independently conducted literature screening,data extraction,evaluation and inclusion in the literature,using RevMan 5.4.1 software for meta-analysis.Results:A total of 11 literatures were included and 936 patients were enrolled.Meta analysis shows that compared with routine nursing,Montessori method is helpful to improve the overall cognitive function(standardized mean difference=1.53,95%confidence interval(1.32,1.73),P<0.01),activities of daily living and reduce the incidence of adverse events(relative risk=0.37,95%confidence interval(0.21,0.63),P<0.01)in patients with Alzheimer’s disease.Conclusion:Montessori method is helpful to improve the overall cognitive function,activities of daily living and reduce the incidence of adverse events in patients with senile dementia.Affected by the included study,it still needs to be confirmed by multi center and large sample randomized controlled study.

Effectiveness of cognitive behavior therapy for sleep disturbance and glycemic control in persons with type 2 diabetes mellitus:A community-based randomized controlled trial in China

BACKGROUND Poor sleep quality is a common clinical feature in patients with type 2 diabetes mellitus(T2DM),and often negatively related with glycemic control.Cognitive behavioral therapy(CBT)may improve sleep quality and reduce blood sugar levels in patients with T2DM.However,it is not entirely clear whether CBT delivered by general practitioners is effective for poor sleep quality in T2DM patients in community settings.AIM To test the effect of CBT delivered by general practitioners in improving sleep quality and reducing glycemic levels in patients with T2DM in community.METHODS A cluster randomized controlled trial was conducted from September 2018 to October 2019 in communities of China.Overall 1033 persons with T2DM and poor sleep quality received CBT plus usual care or usual care.Glycosylated hemoglobin A1c(HbAlc)and sleep quality[Pittsburgh Sleep Quality Index(PSQI)]were assessed.Repeated measures analysis of variance and generalized linear mixed effects models were used to estimate the intervention effects on hemoglobin A1c and sleep quality.RESULTS The CBT group had 0.64,0.50,and 0.9 lower PSQI scores than the control group at 2 mo,6 mo,and 12 mo,respectively.The CBT group showed 0.17 and 0.43 lower HbAlc values than the control group at 6 mo and 12 mo.The intervention on meanΔHbAlc values was significant at 12 mo(t=3.68,P<0.01)and that meanΔPSQI scores were closely related toΔHbAlc values(t=7.02,P<0.01).Intentionto-treat analysis for primary and secondary outcomes showed identical results with completed samples.No adverse events were reported.CONCLUSION CBT delivered by general practitioners,as an effective and practical method,could reduce glycemic levels and improve sleep quality for patients with T2DM in community.

Components of complex interventions for healthcare: A narrative synthesis of qualitative studies

Objective:Qualitative research on therapeutic components is necessary to evaluate the efficacy of complex interventions in healthcare.As few qualitative syntheses have been conducted,this study aimed to derive a new conceptual framework for understanding the components of complex interventions and provide evidence for the implementation and evaluation of complex healthcare interventions.Methods:A systematic search of seven databases was conducted to identify qualitative studies that explored components of complex healthcare interventions.Meta-ethnography was used to analyze the data and thematic analysis was used to build the conceptual framework.Results:Of the 35 included studies,most complex interventions were non-pharmacological,with cancer accounting for 22%,mental health for 14%,and stroke for 8%.Half of the studies were conducted in the United Kingdom.Three main categories emerged:what should healthcare workers do?what qualifications should they have?and what should patients do?Five main themes were identified:psychological,biological,cognitive and behavioral,environmental,and social support.Conclusion:This analysis provides a reference for designing components of complex interventions in further studies.

Early psychological interventions for psychosis

The manuscript correspond to an editorial in order to assess the most important and effective interventions for people with psychosis in the early stages.

Effect of distinct psychological interventions on changes in selfreported distress,depression and loneliness among older adults during COVID-19

BACKGROUND Older adults have been considered a primary at-risk population during the coronavirus disease 2019(COVID-19)pandemic,and many efforts have been and still are directed toward supporting them and enhancing their capacity to cope with the pandemic.Evidence shows that by enhancing proactive coping abilities through psychological interventions,in which cognitive-behavioral and mindfulness techniques are taught and practiced effectively,these interventions have supported older adults throughout the pandemic.However,the underlying mechanisms by which specific intervention components affect various mental states such as distress,depression and loneliness among older adults remain unclear and warrant investigation.AIM To determine the effect of an intervention using cognitive-behavioral and mindfulness techniques on changes in distress,depression and loneliness.METHODS We performed a secondary analysis on data from a previous study in which community-dwelling older adults attended a short-term,internet-based intervention during the first COVID-19 wave in Israel.The intervention included seven sessions during which various cognitive-behavioral and mindfulness techniques were learned and practiced.In-session changes in psychological distress were measured using the Subjective Units of Distress Scale(SUDS),which participants rated at the beginning and end of each session.Participants also filled out questionnaires that evaluated levels of depression[Patient Health Questionnaire(PHQ-9)]and loneliness(UCLA loneliness Scale)prior to and after the entire intervention process.The effect of in-session changes in the SUDS on changes in post-intervention depression and loneliness levels were assessed,as a proxy for distinct technique effectiveness.RESULTS The findings indicated in-session differences in terms of a decrease in psychological distress(SUDS).Sessions that included relaxation exercises and guided imagery,as well as sessions that included cognitive restructuring and mindfulness meditation,demonstrated the largest decreases in in-session psychological distress(≥35%).Two multivariate regression models,one for levels of post-intervention depression(PHQ-9 score)and the other for levels of post-intervention loneliness(UCLA loneliness score),were fitted.The results revealed two statistically significant explanatory variables for depression:The SUDS difference for sessions in which cognitive restructuring and mindfulness meditation were practiced,beta=-0.25,95%CI:-1.23 to-0.1,and the pre-intervention level of depression,beta=0.62,95%CI:0.37-0.75.The second model for loneliness revealed only one significant explanatory variable:The SUDS difference for sessions in which relaxation and guided imagery were practiced,beta=0.41,95%CI:0.14-0.65.CONCLUSION Different psychological techniques seem to have different effects on distress,loneliness and depression.Understanding the pathways by which distinct techniques affect negative mental symptoms has implications for future intervention design.

认知行为干预对上消化道早癌行内镜下黏膜剥离术患者的效果研究

目的探讨基于人文关怀理念的认知行为干预对上消化道早癌患者疼痛、心理和康复效果的影响。方法选择196例上消化道早期癌症行内镜下黏膜剥离术(ESD)患者,随机分为对照组和观察组,每组98例。对照组给予上消化道早癌ESD知识宣教,观察组在此基础上给予基于人文关怀理念的认知行为干预。比较2组康复情况、疼痛视觉模拟评分法(VAS)评分、焦虑自评量表(SAS)评分、一般自我效能感量表(GSES)评分、术后并发症。结果观察组的术后肛门排气时间、术后首次排便时间和术后住院时间为(24.67±8.25)h、(43.90±10.27)h、(9.38±2.02)d,分别短于对照组的(27.83±9.40)h、(50.03±12.85)h、(10.26±2.37)d;手术24、48、72 h后观察组VAS评分为(2.63±0.67)、(1.84±0.52)、(1.33±0.38)分,分别低于对照组的(2.89±0.70)、(2.06±0.58)、(1.47±0.42)分;观察组干预后SAS评分为(38.73±7.40)分,低于对照组的(42.05±8.01)分;观察组干预后的GSES评分为(31.53±6.27)分,高于对照组的(29.28±5.96)分,差异均有统计学意义(P<0.05)。2组总并发症发生率比较,差异无统计学意义(P>0.05)。结论对上消化道早癌患者实施基于人文关怀理念的认知行为干预可减轻疼痛和焦虑情绪,促进患者快速康复。

体操游戏干预促进幼儿自我控制和运动协调能力的实验研究

目的:检验体操游戏干预对幼儿自我控制、运动协调的影响。方法:以杭州市某幼儿园两个园区的114名3~5岁幼儿为实验对象(其中实验组58人),采用准实验不等同比较组前后测设计,对实验组进行为期10周、每周2次、每次20~30 min的体操游戏干预,同时对照组进行户外身体活动,干预前后测量幼儿的认知自控、行为自控和运动协调能力。结果:2(时间)×2(实验处理)重复测量方差分析显示,认知自控的交互作用显著(F=6.72,P<0.05,η_(p)^(2)=0.064),行为自控的变化不具有统计学意义(F=0.15,P>0.05,η_(p)^(2)=0.002);精细动作、运动协调总分的交互作用非常显著(F_(精细动作)=12.48,P<0.001,η_(p)^(2)=0.11;F_(运动协调总分)=10.76,P<0.001,η_(p)^(2)=0.099),定位和抓取的交互作用显著(F=5.93,P<0.05,η_(p)^(2)=0.057),动静态平衡的变化不具有统计学意义(F=1.10,P>0.05,η_(p)^(2)=0.011)。结论:体操游戏干预能够促进幼儿认知自我控制和运动协调能力及精细动作、手眼协调能力的发展。

ESPCS干预对髋关节置换术患者疾病认知能力及健康行为的护理效果观察

目的探讨ESPCS护理干预对髋关节置换术患者疾病认知能力及健康行为的影响。方法选取2022年5月—2023年5月湖北省十堰市太和医院骨科收治的髋关节置换术患者96例为研究对象。按照组间基本特征具有可比性的原则将患者分为观察组和对照组,每组48例,对照组行常规护理,观察组实施ESPCS护理干预,内容包括讲解(explanation,E)、模拟(simulation,S)、练习(practice,P)、沟通(communication,C)、支持(support,S),比较两组患者干预前后疾病认知能力、健康行为、髋关节康复与活动度情况及生活质量改善情况。结果干预前,两组患者疾病认知能力总评分及髋关节疾病机制、髋关节置换术治疗原理、髋关节置换术后并发症预防、髋关节术后护理措施评分比较差异无统计学意义(P>0.05);干预后,观察组疾病认知能力总评分及髋关节疾病机制、髋关节置换术治疗原理、髋关节置换术后并发症预防、髋关节术后护理措施评分高于对照组,组间比较差异有统计学意义(P<0.05)。干预前,两组患者健康促进生活方式量表(HPLP-Ⅱ)总评分及各维度评分比较差异无统计学意义(P>0.05);干预后,观察组HPLP-Ⅱ总评分及相关维度评分高于对照组,组间比较差异有统计学意义(P<0.05)。干预前,两组患者髋关节功能评分(HHS)评分及髋外展角、髋后伸角、髋前屈角比较差异无统计学意义(P>0.05);干预后,观察组HHS评分高于对照组,髋外展角、髋后伸角、髋前屈角大于对照组,组间比较差异有统计学意义(P<0.05)。干预前,两组患者生活质量综合评定量表(GQOL-74)各维度评分比较差异无统计学意义(P>0.05);干预后,观察组GQOL-74各维度评分高于对照组,组间比较差异有统计学意义(P<0.05)。结论对髋关节置换术患者实施ESPCS护理干预,可有助于患者疾病认知能力及健康行为提升,从而有效改善患者髋关节功能,提升患者生活质量。

认知行为干预对固定矫正器正畸患者心理负担和自护能力的影响

目的:探讨认知行为干预对固定矫正器正畸患者心理负担和自护能力的影响。方法:选取2020年1月-2021年1月某院收治的90例固定矫正器正畸患者为研究对象,按照入院先后分为对照组和观察组,每组各45例;对照组采取常规干预,观察组采取认知行为干预;对比两组治疗依从性,干预前后心理负担[汉密尔顿焦虑自评量表(HAMA)、汉密尔顿抑郁自评量表(HAMD)]、舒适度和疼痛情况[Kolcaba简化舒适状况量表、视觉模拟评分法(VAS)]、自护能力[自我护理能力量表(ESCA)]及自我效能[口腔保健自我效能量表(SESS)]。结果:两组治疗依从性比较,观察组高于对照组(χ^(2)=5.404,P<0.05)。干预后,两组HAMA、HAMD评分均下降(P<0.05),且观察组均低于对照组(t=-8.993,-7.187;P<0.05);干预后,两组Kolcaba量表评分均升高(P<0.05),且观察组均高于对照组(t=10.804,P<0.05);两组VAS评分均降低(P<0.05),且观察组均低于对照组(t=-15.429,P<0.05);干预后,两组自我概念、健康知识水平、自我护理技能、自我护理责任感及ESCA量表总分均高于干预前(P<0.05),且观察组均高于对照组(t=6.692,3.663,5.640,5.183;P<0.05);干预后,两组口腔就诊、正确刷牙、平衡饮食得分均高于干预前(P<0.05),且观察组均高于对照组(t=4.295,7.013,7.427;P<0.05)。结论:对固定矫正器正畸患者采用认知行为干预效果显著,可提高治疗依从性,减轻心理负担,缓解疼痛,提高舒适度、自护能力和口腔保健自我效能。

认知行为干预对不同认知功能状态老年人营养改善效果的影响

目的分析对住院老年人进行认知行为干预对其营养状态的改善效果。方法以我院2014~2017年住院离退休干部400例为研究对象,按随机数字表法分为对照组和观察组各200例,评估不同老年人的认知功能状态,再展开不同的护理方案,对照组进行常规干预,观察组在此基础上加强认知行为干预,比较两组的精神状态、日常生活活动能力、认知功能和生活质量。结果干预后,观察组简易状态检查量表(MMSE)、日常生活能力量表(ADL)、蒙特利尔认知评估量表(MoCA)、健康状况调查问卷(SF-6)评分均高于对照组,差异有统计学意义(P<0.05)。结论认知行为干预是一种有效的方法来改善老年人的营养状况,提升患者自我认知,减少疾病的风险。

认知行为治疗联合积极心理干预对酒精使用障碍伴抑郁患者的效果

目的探究认知行为治疗(CBT)联合积极心理干预对酒精使用障碍(AUD)伴抑郁患者酒精戒断反应、负性情绪以及复饮情况的影响。方法将184例AUD伴抑郁患者按照随机数字表法分为对照组和研究组,各92例。对照组患者给予常规药物治疗,研究组患者在对照组基础上给予CBT联合积极心理干预。比较治疗前后两组患者修订版临床酒精戒断症状评定量表(CIWAAr)、宾夕法尼亚酒精渴求量表(PACS)、汉密顿焦虑量表(HAMA)、汉密顿抑郁量表(HAMD)、药物成瘾者生存质量测定量表(QOL-DA)评分,并随访半年统计两组患者的复饮情况。结果对照组脱落2例,研究组脱落0例,最终对照组纳入90例,研究组纳入92例。治疗后,两组患者CIWA-Ar、PACS、HAMA、HAMD评分均低于治疗前,且研究组低于对照组(P<0.01)。治疗后,两组患者QOL-DA各维度评分均高于治疗前,且研究组高于对照组(P<0.01)。随访8周、16周、24周,研究组患者复饮率均低于对照组(P<0.05)。结论对AUD伴抑郁患者在常规药物治疗的基础上给予CBT联合积极心理干预,可有效帮助患者戒断酒精依赖,减轻其负性情绪,降低复饮率,改善生存质量。

标准认知行为干预对中青年乳腺癌化疗患者心理状态的影响

目的:探讨标准认知行为干预对中青年乳腺癌化疗患者心理状态的影响。方法:选取2022年3月—2023年3月期间在南通大学附属医院进行化疗的乳腺癌患者作为本次研究对象,其中符合纳入标准的患者共计150例。通过随机数表法将其分为对照组和实验组,对照组采用常规护理方法,实验组采用标准认知行为干预。比较两组患者的焦虑、抑郁心理评分和生存质量评分。结果:实验组的焦虑、抑郁评分优于对照组(P<0.05)。实验组生存质量评分优于对照组(P<0.05)。结论:标准认知行为干预对中青年乳腺癌化疗患者心理状态治疗效果明显,具有较好的临床应用价值。

认知行为干预对功能性大便失禁患者焦虑和抑郁状态的影响

目的探讨认知行为干预替代常规护理方法对功能性大便失禁患者焦虑及抑郁情绪心理状态的影响。方法将该院2021年6月至2022年6月收治的40例功能性大便失禁患者按随机数字表法分为对照组和观察组,每组20例。2组患者均给予常规治疗(盆底肌训练+触发电刺激训练),对照组患者予以常规护理,观察组患者予以认知行为干预,观察4周。比较2组患者干预前后临床疗效、Wexner克利夫兰肛门失禁评分、焦虑自评量表、抑郁自评量表。结果观察组总有效率[90.0%(18/20)]高于对照组[75.0%(15/20)],差异有统计学意义(χ^(2)=3.491,P<0.05)。干预后2组患者Wexner克利夫兰肛门失禁评分、焦虑自评量表评分、抑郁自评量表评分均较干预前降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。结论通过认知行为干预可以明显缓解功能性大便失禁患者的焦虑和抑郁状态,从而增强治疗效果,对患者的恢复也有积极影响。

无痛理念下认知行为模式干预对食管癌术后患者疼痛程度和心理状态的影响

目的探讨无痛理念下认知行为模式干预对食管癌术后患者疼痛程度和心理状态的影响。方法依据干预方法的不同将107例食管癌患者分为无痛组(n=56)和常规组(n=51),常规组患者接受常规干预,无痛组患者接受无痛理念下认知行为模式干预。比较两组患者疼痛程度[视觉模拟评分法(VAS)、疼痛分级指数(PR)]、负性情绪[焦虑自评量表(SAS)、抑郁自评量表(SDS)]、自我管理能力[自我管理能力量表(SMS)]、生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]和并发症发生情况。结果干预后,两组患者VAS、PR、SAS、SDS评分均低于本组干预前,无痛组患者VAS、PR、SAS、SDS评分均低于常规组,差异均有统计学意义(P﹤0.05)。干预后,两组患者SMS各维度评分及总分均高于本组干预前,无痛组患者SMS各维度评分及总分均高于常规组,差异均有统计学意义(P﹤0.05)。干预后,两组患者EORTC QLQ-C30各维度评分均高于本组干预前,无痛组患者EORTC QLQ-C30各维度评分均高于常规组,差异均有统计学意义(P﹤0.05)。无痛组患者的并发症总发生率为7.14%,低于常规组患者的23.53%,差异有统计学意义(P﹤0.05)。结论无痛理念下认知行为模式干预可有效缓解食管癌患者术后疼痛程度,减轻焦虑和抑郁情绪,强化自我管理能力,提高生活质量,从而降低并发症发生率。

五行音乐疗法联合认知行为干预对脑卒中患者康复期的影响

目的 探讨中医五行音乐疗法联合认知行为干预对脑卒中患者运动功能、日常生活能力及心理状态的影响。方法选取2021年7月—2022年12月在南昌某三甲医院康复科住院的首发脑卒中患者80例,采用随机数字表法分为对照组和试验组,各40例。两组患者都行脑卒中常规康复护理,试验组加用中医五行音乐疗法联合认知行为干预,比较两组运动功能评分[Fugl-Meyer运动功能评估量表(FMA)评分]、日常生活能力量表(ADL)评分、心理状态评分[汉密尔顿抑郁量表(HAMD)评分]。结果 入院干预4、8周后,两组FMA评分、ADL评分、HAMD评分比较,差异均有统计学意义(P<0.05);不同时间、不同组别及时间-组别交互差异均有统计学意义(P<0.05)。结论 在常规康复护理的基础上行中医五行音乐联合认知行为干预,有利于改善脑卒中患者的运动功能和日常生活能力,消除其一些不良心理状态,值得临床推广应用。

认知行为干预用于慢性阻塞性肺疾病护理效果分析

目的探讨认知行为干预用于慢性阻塞性肺疾病护理的效果。方法选取医院2022年12月至2023年12月收治的慢性阻塞性肺疾病患者130例,采用AB球方法分为观察组和对照组,各65例。对照组患者实施常规护理,观察组患者在此基础上融入认知行为干预。结果观察组患者的汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)评分均显著低于对照组,治疗依从性显著高于对照组(P<0.05)。结论认知行为干预用于慢性阻塞性肺疾病护理的效果良好,可显著改善患者的心理健康,提升依从性。

个性化护理结合认知行为干预对2型糖尿病肥胖女性糖脂代谢、焦虑、抑郁及生活质量的影响

目的分析个性化护理结合认知行为干预对2型糖尿病肥胖女性糖脂代谢、焦虑、抑郁及生活质量的影响。方法选取2022年2月—2024年2月潍坊市益都中心医院收治的128例2型糖尿病肥胖女性患者为研究对象,按护理方法不同分为对照组(n=64)和观察组(n=64),对照组开展常规护理,观察组采用个性化护理结合认知行为干预,比较两组血糖指标、心理状态评分、生活质量评分、护理依从性。结果护理后,观察组空腹血糖、餐后2 h血糖水平、焦虑、抑郁评分均低于对照组,护理依从性、生活质量评分均高于对照组,差异有统计学意义(P均<0.05)。结论2型糖尿病肥胖女性应用个性化护理结合认知行为干预的效果确切,可改善患者的糖脂代谢水平、焦虑、抑郁情绪及生活质量。