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To Investigate the Effect of Using Ethanol Containing Wipes in Collecting Blood for the Measurement of Alcohol Concentration
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作者 Takami Nakao Atsushi Nitta +3 位作者 Hiroshi Nishioka Munehiro Katagi Noriko Tsuda Yasuhide Kitazawa 《Pharmacology & Pharmacy》 2021年第10期208-218,共11页
<span style="font-family:""><span style="font-family:Verdana;">This study was aimed to establish whether the skin preparation using ethanol-containing skin antiseptics causes ethan... <span style="font-family:""><span style="font-family:Verdana;">This study was aimed to establish whether the skin preparation using ethanol-containing skin antiseptics causes ethanol contamination through blood collection. Venous blood was collected from 40 healthy volunteers according to the national guidelines for blood sampling, with four sequential procedures as follows: 1) collecting blood immediately (within 5 seconds) after cleaning the skin with an individually packaged type of ethanol-containing wipe, 2) collecting blood 1 minute after cleaning the skin with an individually packaged type of ethanol-containing wipe, 3) collecting immediately (within 5 seconds) after cleaning the skin with a traditional cleaning method (thoroughly ethanol-impregnated wipe, and 4) collecting 1 minute after cleaning the skin with a traditional cleaning method. Each sequential procedure was p</span><span style="font-family:Verdana;">erformed with and without the ethanol-containing wipe used for sk</span><span style="font-family:Verdana;">in cleaning on the puncture site on their right and left arms at the time the needle was withdrawn, respectively. The collected specimens were subjected to the determination of ethanol by using headspace gas chromatography-mass spectrometry. In every 80 blood specimens obtained from 40 participants, ethanol was undetectable (<0.001 mg/mL). This study demonstrates that disinfection using ethanol-containing skin antiseptics is unlikely to cause ethanol contamination through blood collection regardless of skin preparation technique according to the guidelines for blood sampling. This may have implications in forensic science. 展开更多
关键词 Blood Alcohol Content skin antiseptic Contamination of Ethanol
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